Clinical trials: Acute Cardiac Syndrome
Acute Coronary Syndrome, Acute Myocardial Infarction
Comparison Between Ticagrelor Versus Very Low Dose Rivaroxaban With Clopidogrel
A total of 50 participants diagnosed with ACS (group A ticagrelor 180mg/d, n=25), group B (clopidogrel 75mg + rivaroxaban 5mg/ d, n=25)) were consecutively enrolled and treated with study drugs on top of aspirin (100mg/d) for 1…
- Conditions
- Acute Coronary Syndrome, Acute Myocardial Infarction, Unstable Angina
- Trial name
- NCT03481257
- Where
- South Korea
- Volunteers
- 56 people
- Sponsor
- Seoul National University Hospital
Cardiology, Acute Coronary Syndrome
Echocardiography by Non-cardiologist in Early Management of Patients With Chest Pain
The aim of the study is to find out the benefit of echocardiography, which is performed by a physican without a cardiological or radiological specialty.
- Conditions
- Cardiology, Acute Coronary Syndrome, Echocardiography
- Trial name
- ENDEMIC (NCT05306730)
- Testing
- ECHOcardiography, Point-of-Care UZ
- Volunteers
- 430 people
- Sponsor
- University of Defence, Faculty of Military Health Sciences
Acute Coronary Syndrome, Coronary Stent Occlusion
Perioperative Management of Patients With Coronary Stents Undergoing Noncardiac Surgery
The purpose of this study is to evaluate and monitor perioperative management of patients with coronary stents undergoing noncardiac surgery.
- Conditions
- Acute Coronary Syndrome, Coronary Stent Occlusion, Surgery
- Trial name
- RegistStents (NCT01171612)
- Where
- 13 sites in Spain
- Volunteers
- 483 people
- Sponsor
- Corporacion Parc Tauli
A Total of 234 Patients With Acute Coronary Syndrome Who Will Undergo OPCAB.
Impact of High-dose Pretreatment of Rosuvastatin in Patients With Acute Coronary Syndrome Following Off-pump Coronary Artery Bypass: Results From the HIROP-ACS (HIgh-dose Pretreatment of Rosuvastatin During Off-Pump Coronary Bypass in Acute Coronary Syndrome) Study
Periprocedural treatment with high-dose statins is known to have cardioprotective and pleiotropic effects, such as anti-thrombotic and anti-inflammatory actions.
- Trial name
- NCT01971606
- Testing
- Rosuvastatin
- Where
- South Korea
- Volunteers
- 234 people
- Sponsor
- Yonsei University
High Grade Obstructive NSTE-ACS
Infrasensor for Early Detection of a High-grade Obstructive NSTE-ACS
The objective of this prospective, cross-sectional, multicenter pivotal trial study is to validate Infrasensor's clinical performance for the detection of high grade obstructive NSTE-ACS.
- Trial name
- NCT07464704
- Where
- 6 sites in United States
- Volunteers
- 350 people
- Sponsor
- Remote Cardiac Enablement
Chest Pain, Emergency Medicine
A Study to Assess the Accuracy of Magnetocardiography (MCG) to Diagnose True Ischemia in Patients With Chest Pain in the ED
The purpose of the research is to see if patients that come to the Emergency Department with chest pain can be more accurately and more quickly diagnosed by magnetocardiography (MCG) to see if their chest pain is caused by…
- Trial name
- MCG (NCT05809648)
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Mayo Clinic
Acute Myocardial Infarction
Does Heme Oxygenase-1 Induction Ameliorate Cardiac Injury After Myocardial Infarction?
Rationale: A safety and dose defining study in which the investigators hypothesize that in patients with acute coronary syndrome without ST-elevation (NSTEMI) treatment with heme arginate results in better clinical outcome by…
- Trial name
- HAEM (NCT00483587)
- Testing
- Heme arginate
- Where
- Netherlands
- Volunteers
- 15 people
- Sponsor
- University Medical Center Groningen
Myocardial Infarction, Acute Coronary Syndrome
HeartHome: A Nurse-Driven, Home-Based Cardiac Rehabilitation Program
The purpose of this implementation trial is to execute a nurse-led, home-based cardiac rehabilitation (HBCR) program, evaluate the program's impact on patient outcomes over 6 months; and compare outcomes of HeartHome (HH)…
- Conditions
- Myocardial Infarction, Acute Coronary Syndrome, ST-segment Elevation Myocardial Infarction (STEMI), Non-ST-Segment Elevation Myocardial Infarction (NSTEMI)
- Trial name
- NCT04131816
- Testing
- HeartHome
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of North Carolina, Chapel Hill
Acute Coronary Syndrome, Acute Myocardial Infarction
ShorT and OPtimal Duration of Dual AntiPlatelet Therapy-2 Study for the Patients With ACS
The purpose of this study is to evaluate the safety of reducing dual antiplatelet therapy (DAPT) duration to 1 month after implantation of the everolimus-eluting cobalt-chromium stent (CoCr-EES) under the setting of acute…
- Conditions
- Acute Coronary Syndrome, Acute Myocardial Infarction, Coronary Artery Disease, Percutaneous Coronary Intervention
- Trial name
- STOPDAPT-2 ACS (NCT03462498)
- Testing
- 1-months DAPT, 12-month DAPT
- Where
- Japan
- Volunteers
- 3,008 people
- Sponsor
- Kyoto University, Graduate School of Medicine
Coronary Artery Disease, Myocardial Infarction
Barts Sex-CAD Database - Sex Hormones and Inflammatory Status in Coronary Artery Disease
There is a lack of understanding of how Coronary Artery Disease (CAD) - meaning the blocking or furring up of the arteries of the heart - starts and progresses in women.
- Conditions
- Coronary Artery Disease, Myocardial Infarction, Acute Coronary Syndrome, Atherosclerosis
- Trial name
- NCT06327984
- Where
- United Kingdom
- Volunteers
- 6,000 people
- Sponsor
- Queen Mary University of London
Acute Coronary Syndrome
Healthy Heart Habits-2
Sixty adults who have experienced acute coronary syndrome within the past 2-12 months from three states (Rhode Island, North Carolina, Minnesota) will be randomized to either (1) a coaching program for depressed mood and health…
- Trial name
- HHH-2 (NCT06440278)
- Testing
- Behavioral Activation for Health and Depression (BA-HD), Enhanced Usual Care
- Where
- 3 sites in United States
- Volunteers
- 39 people
- Sponsor
- The Miriam Hospital
Emergencies, Heart Failure
The Use of a Monitoring Device by General Practitioners During Out-of-hours Care
All calls that end up on the out-of-hours general practitioners' service (OHGPS), which contain a demand for an urgent home visit, are passed on to the on-call general practitioner (GP).
- Conditions
- Emergencies, Heart Failure, Pulmonary Embolism, Acute Exacerbation of Chronic Obstructive Pulmonary Disease
- Trial name
- NCT05222711
- Testing
- Use of the PICO(TM) monitoring device
- Where
- Belgium
- Volunteers
- 866 people
- Sponsor
- KU Leuven
Acute Coronary Syndromes
A Study of Apixaban in Patients With Atrial Fibrillation, Not Caused by a Heart Valve Problem, Who Are at Risk for Thrombosis (Blood Clots) Due to Having Had a Recent Coronary Event, Such as a Heart Attack or a Procedure to Open the Vessels of the Heart
The purpose of this study is to determine if Apixaban is safer than a Vitamin K Antagonist given for 6 months in terms of bleeding in patients with an irregular heart beat (atrial fibrillation) and a recent heart attack or a…
- Trial name
- NCT02415400
- Testing
- Apixaban, vitamin K antagonist, Acetylsalicylic acid
- Where
- 626 sites in United States, Argentina and 35 more
- Volunteers
- 4,614 people
- Sponsor
- Bristol-Myers Squibb
Smoking Cessation, Acute Coronary Syndrome
Post Acute Coronary Event Smoking Study
Smoking and depressed mood are both predictive of mortality following Acute Coronary Syndrome. However, to date, no counseling treatment has been designed to target smoking cessation and manage mood in this population.
- Trial name
- PACES (NCT01964898)
- Testing
- Behavioral Activation (BA), Standard Smoking Cessation Counseling, Nicotine patch
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- The Miriam Hospital
Coronary Artery Disease, Myocardial Ischemia
Drug-Coated Balloon vs. Drug-Eluting Stent for Clinical Outcomes in Patients With Large Coronary Artery Disease
Prospective, randomised, open-label, international multicenter trial to evaluate the safety and efficacy of drug-coated balloon (DCB) treatment compared to drug-eluting stenting (DES) in patients with large coronary artery…
- Conditions
- Coronary Artery Disease, Myocardial Ischemia, Acute Coronary Syndrome, Coronary Stenosis
- Trial name
- REVERSE (NCT05846893)
- Testing
- SeQuent® Please NEO drug-coated balloon catheter, Current-generation drug-eluting stent
- Where
- 21 sites in Malaysia, Singapore and 2 more
- Volunteers
- 1,436 people
- Sponsor
- B. Braun Medical Industries Sdn. Bhd.
Antiplatelet Therapy, Coronary Artery Disease
LOwer Maintenance Dose TICagrelor in Acute Coronary Syndrome Patients Undergoing Percutaneous Coronary Intervention
The hypothesis in this study was that ticagrelor switched to 60 mg after 1 month of standard dose, with antiplatelet activity that is not inferior to the standard dose and better than 75 mg clopidogrel for patients with ACS after…
- Conditions
- Antiplatelet Therapy, Coronary Artery Disease, Percutaneous Coronary Intervention
- Trial name
- LOTIC (NCT04060914)
- Testing
- Ticagrelor 90mg, Ticagrelor 90mg/60mg, Clopidogrel 75mg
- Where
- China
- Volunteers
- 225 people
- Sponsor
- Beijing Anzhen Hospital
Coronary Artery Disease
Fenoldopam for Prevention of Acute Kidney Injury
Patients with acute coronary syndromes (ACS) are at increased risk for acute kidney injury (AKI) when they undergo urgent/emergency coronary angiography.
- Trial name
- FANCY (NCT01690832)
- Testing
- standard saline infusion, fenoldopam infusion
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- University of Roma La Sapienza
Acute Coronary Syndrome
OPT-CAD Score GUIded Dual ANtiplatelet De-esCalation Time
Monotherapy with a P2Y12 inhibitor after a minimum period of DAPT following percutaneous coronary intervention (PCI) is an emerging de-escalation antiplatelet strategy in recent years.
- Trial name
- OPT-GUIDNACE (NCT06216821)
- Testing
- standard DAPT, OPT-CAD score guided DAPT de-escalation
- Where
- China
- Volunteers
- 3,490 people
- Sponsor
- Shenyang Northern Hospital
Cardiovascular Diseases, Acute Coronary Syndrome
The IndONEsia ICCU Registry: a Multicenter Cohort of Intensive Cardiovascular Care Units Patients in Indonesia
Patients in the Intensive Cardiovascular Care Unit (ICCU) often present with cardiovascular disease (CVD) issues accompanied by various non-cardiovascular conditions.
- Conditions
- Cardiovascular Diseases, Acute Coronary Syndrome, Heart Failure, Heart Disease, Coronary
- Trial name
- NCT06265714
- Where
- 9 sites in Indonesia
- Volunteers
- 12,950 people
- Sponsor
- Universitas Indonesia
Acute Coronary Syndrome
Harmonizing Optimal Strategy for Treatment of Coronary Artery Diseases Trial - Comparison of REDUCTION of PrasugrEl Dose & POLYmer TECHnology in ACS Patients (HOST REDUCE POLYTECH RCT Trial)
Study objectives 1. To compare the safety and long-term efficacy of coronary stenting with biostable polymer drug-eluting stent (Promus PremierTM, Xience Alpine®, Resolute Onyx®) with biodegradable polymer drug-eluting stent…
- Trial name
- NCT02193971
- Testing
- BS-DES (Biostable polymer drug-eluting stent), BD-DES (Biodegradable polymer drug-eluting stent), Prasugrel 5mg
- Where
- South Korea
- Volunteers
- 3,429 people
- Sponsor
- Seoul National University Hospital
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.