Clinical trials: Acute Cardiac Syndrome
Cardiac Rehabilitation, Acute Coronary Syndrome
Using a Connected Application to Maintain Physical Activity After Cardiac Rehabilitation
Maintaining physical activity after cardiac rehabilitation has a major role in disease progression and patient prognosis. 6 months after the cardiac rehabilitation, we find during a nursing interview that many patients do not…
- Conditions
- Cardiac Rehabilitation, Acute Coronary Syndrome, Heart Failure
- Trial name
- APA&CO2 (NCT05646849)
- Testing
- Connected application
- Where
- France
- Volunteers
- 208 people
- Sponsor
- University Hospital, Angers
Acute Coronary Syndrome
FRANCIS-ACS Trial: A Study of the Safety and Efficacy of A 002 in Subjects With Acute Coronary Syndromes
The objective of this study is to evaluate the safety and efficacy of A 002 when added to high dose atorvastatin in subjects with an acute coronary syndrome (ACS)
- Trial name
- FRANCIS-ACS (NCT00743925)
- Testing
- Varespladib Methyl (A-002)
- Where
- 44 sites in Georgia, Russia and 1 more
- Volunteers
- 625 people
- Sponsor
- Anthera Pharmaceuticals
Lung Neoplasms, Respiratory Failure
Clearance Of Mucus In Stents (COMIS)
The goal of this clinical research study is to compare the effects of sodium bicarbonate to normal saline when used for clearing mucus blockage in patients with airway stents.
- Conditions
- Lung Neoplasms, Respiratory Failure, Pneumonia, Acute Coronary Syndromes
- Trial name
- NCT01370278
- Testing
- Normal Saline, Sodium Bicarbonate
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Chest Pain, Acute Coronary Syndrome
Dexmedetomidine for Reversal of Cocaine's Effects on the Heart
This study will use myocardial contrast echocardiography performed during a continuous intravenous infusion of Definity microbubbles (Perflutren lipid microbubbles) to determine if dexmedetomidine (an intravenous central…
- Trial name
- NCT01927640
- Testing
- Dexmedetomidine, Normal Saline, Intranasal cocaine
- Where
- United States
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Acute Coronary Syndrome
Antiplatelet Therapy in Acute Coronary Syndrome(ACS). Safety and Efficacy of Switching Antiplatelet
This study aims to describe antiplatelet therapy in ACS in Andalusia and make an assessment of efficacy and safety of hospital use Prasugrel / ticagrelor vs.
- Trial name
- NCT02500290
- Where
- 8 sites in Spain
- Volunteers
- 2,000 people
- Sponsor
- Fundación Pública Andaluza Progreso y Salud
Coronary Artery Disease, Acute Coronary Syndrome
Τicagrelor Versus Prasugrel in Diabetic Patients: a Pharmacodynamic Study
This is a prospective, randomized, single-center, single blind, investigator initiated, two period study of crossover design. Diabetic patients with Acute Coronary Syndrome (ACS), treated with oral and/or parenteral hypoglycaemic…
- Trial name
- NCT01642940
- Testing
- Prasugrel, Ticagrelor
- Where
- Greece
- Volunteers
- 30 people
- Sponsor
- University of Patras
Severe Sepsis, Cardiac Arrest
Examination of the Impact of Better Surveillance and Communication of Patient Deterioration on Patient Related Outcomes
A hospitals manual method of patient monitoring will be implemented in an automated system and supported by an early patient deterioration detection for timely escalation.
- Conditions
- Severe Sepsis, Cardiac Arrest, Respiratory Failure
- Trial name
- NCT01692847
- Where
- United Kingdom
- Volunteers
- 678 people
- Sponsor
- Philips Healthcare
Acute Coronary Syndrome
Diagnostic Value of Heart-Fatty Acid Binding Protein and Ischemia Modified Albumin as Biochemical Markers on Non ST Segment Elevation Acute Coronary Syndrome at the Emergency Room.
Early diagnostic of non ST elevation coronary syndrome in patients admitted to the emergency room is difficult. Two news biochemical markers have been assessed and studies have suggested that heart fatty binding protein and…
- Trial name
- NCT00714298
- Testing
- Measure of Initial heart fatty acid binding protein and ischemia modified albumin
- Where
- France
- Volunteers
- 700 people
- Sponsor
- University Hospital, Toulouse
Acute Coronary Syndromes
Pain Relief of Metoprolol Versus Metoprolol Plus Morphine in Acute Chest Pain
The primary aim was to evaluate the relief of chest pain during the first 30 minutes among patients who received metoprolol alone as compared with metoprolol plus morphine
- Trial name
- NCT00718406
- Testing
- Metoprolol, metoprolol plus morphine
- Where
- Sweden
- Sponsor
- Sahlgrenska University Hospital
Acute Coronary Syndrome
"Me and My Heart" Study
An electronic device application (APP) "Mein Herz und ich" has been developed specifically for acute coronary syndrome (ACS) patients who are prescribed to Brilique (ticagrelor) to increase adherence to treatment (medication and…
- Trial name
- eMocial (NCT02615704)
- Testing
- Active group with MEMS, Active group without MEMS, Control group with MEMS
- Where
- 31 sites in Germany
- Volunteers
- 677 people
- Sponsor
- AstraZeneca
Obstructive Sleep Apnea of Adult, Acute Coronary Syndrome
OSA-ACS Project: Association of OSA and CPAP Therapy With Outcomes in ACS Patients
Obstructive sleep apnea (OSA) is an increasingly common chronic disorder in adults that has been strongly associated with various forms of cardiovascular disease.
- Trial name
- NCT03362385
- Testing
- Patients with OSA based on sleep study, Patients without OSA based on sleep study
- Where
- China
- Volunteers
- 2,160 people
- Sponsor
- Beijing Anzhen Hospital
Ischemic Heart Disease
GENOSS Coronary Stent Clinical Trial
This study aims to evaluate the efficacy and safety of abluminal biodegradable polymer ultrathin sirolimus-eluting stent (Genoss stent) as compared with a durable-polymer everolimus-eluting stent (Xience stent) in patients with…
- Trial name
- NCT05444452
- Testing
- Implanatation of Genoss DES sirolimus-eluting coronary system, Implanatation of Xience DES everolimus-eluting coronary system
- Where
- South Korea
- Volunteers
- 850 people
- Sponsor
- Samsung Medical Center
Acute Coronary Syndrome, Depression
The Impact of Depression and/or Anxiety on PCI Patients
The purpose of this study is to evaluate how depression and/or anxiety could effect the prognosis of the patients post-ACS after PCI.
- Conditions
- Acute Coronary Syndrome, Depression, Anxiety
- Trial name
- NCT03057691
- Testing
- antidepressive and anti-anxiety therapy
- Where
- China
- Volunteers
- 5,000 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Patients With Acute Coronary Syndrome
Air Pollution, Inflammation and Acute Coronary Syndrome
The objectives of this study are: 1) To determine whether patients with acute coronary syndrome, the level of environmental exposure to particulate air pollutants in the week prior to admission, are related to concentrations of…
- Trial name
- AIRACOS (NCT01799148)
- Testing
- Particulate air pollutants
- Where
- Spain
- Volunteers
- 307 people
- Sponsor
- Fundación Canaria Rafael Clavijo para la Investigación Biomédica
Acute Coronary Syndrome, Myocardial Infarction (MI)
Clinical Echocardiography and S' Wave for Early Recognition of Acute Coronary Syndrome in the Emergency Department, A Prospective Study
The goal of this prospective observational study is to assess the diagnostic accuracy of the tissue Doppler imaging (TDI) S' wave in detecting acute coronary syndrome (ACS) in adult patients presenting to the emergency department…
- Conditions
- Acute Coronary Syndrome, Myocardial Infarction (MI), Non-ST Elevation Myocardial Infarction, Unstable Angina
- Trial name
- CLEAR_ECHO (NCT06860997)
- Testing
- Tissue Doppler Imaging (TDI) S' Wave Echocardiography
- Where
- Belgium
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Acute Coronary Syndrome
Comparison of High and Moderate Intensity Statins in Achieving the Target LDL-C Level After Acute Coronary Syndrome
This study evaluates the effectiveness of high- and moderate-intensity statins in achieving target low-density lipoprotein cholesterol (LDL-C) levels in patients with acute coronary syndrome (ACS).
- Trial name
- NCT06782243
- Testing
- Moderate-Intensity Statins, High-Intensity Statins
- Where
- Pakistan
- Volunteers
- 190 people
- Sponsor
- Khyber Medical University Peshawar
Acute Coronary Syndrome, Myocardial Infarction
Future Optimal Research and Care Evaluation
Rationale: Acute coronary syndrome (ACS) is the leading cause of death worldwide. To improve cardiovascular care, research is needed.
- Trial name
- FORCE-ACS (NCT03823547)
- Where
- 4 sites in Netherlands
- Volunteers
- 99,999 people
- Sponsor
- J.M. ten Berg
Cardiovascular Diseases, Acute Coronary Syndrome
In-Hospital Wearable-Based Monitoring Versus Standard Care in Cardiovascular Disease (INSPIRE)
Patients hospitalized with cardiovascular disease require timely detection of clinical deterioration to prevent adverse outcomes.
- Conditions
- Cardiovascular Diseases, Acute Coronary Syndrome, Heart Failure, Cardiac Arrhythmia
- Trial name
- NCT07622485
- Testing
- thynC Inpatient Monitoring System
- Where
- South Korea
- Volunteers
- 1,500 people
- Sponsor
- Yonsei University
Unstable Angina, Coronary Atherosclerosis
Serp-1 for the Treatment of Acute Coronary Syndrome
Males and females aged 18-80 years who present with ACS (unstable angina and non ST-elevation MI) defined as one or more episodes of angina lasting at least 5 minutes in the last 24 hours before admission and greater than 0.05 mV…
- Conditions
- Unstable Angina, Coronary Atherosclerosis, Coronary Restenosis
- Trial name
- NCT00243308
- Testing
- Serine proteinase-1 (Serp-1)
- Where
- 8 sites in United States, Canada
- Volunteers
- 72 people
- Sponsor
- Viron Therapeutics Inc
Acute Coronary Syndrome
Direct Angioplasty for Non ST Elevation Acute Coronary Events: DANCE Pilot Study
This is a pilot feasibility study to evaluate if patients with ST depression Acute Coronary Syndrome who are taken directly to the catheter laboratory for angiogram and angioplasty +/- stents will fare better that patients who…
- Trial name
- DANCE (NCT01172990)
- Testing
- Immediate Invasive Management, Conventional Management
- Where
- United Kingdom
- Volunteers
- 108 people
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
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