Clinical trials: Acute Cardiac Syndrome
Cardiovascular Complications, Myocardial Infarction
Ankle-Brachial Index Estimating Cardiac Complications After Surgery
Introduction: Patients undergoing noncardiac surgery are at increased risk of cardiovascular complications. The development of methods that can accurately predict the occurrence of these events is of critical importance and large…
- Conditions
- Cardiovascular Complications, Myocardial Infarction, Acute Coronary Syndromes
- Trial name
- ABRACOS (NCT01452282)
- Where
- Brazil
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
ACS - Acute Coronary Syndrome, Oncology
The BRAvAdO Registry
The BRAVADO Registry pretends to identify stratification, diagnosis, total atherosclerotic burden and treatment approaches in oncologic patients with Acute Coronary Syndrome (ACS) and identify strategies to improve health care…
- Trial name
- BRAvAdO (NCT04222608)
- Where
- Brazil
- Volunteers
- 600 people
- Sponsor
- University of Sao Paulo General Hospital
Coronary Artery Disease, Acute Coronary Syndrome
Effect and Efficacy of Onyx™, Zotarolimus-eluting Stent for Coronary Atherosclerosis
The objectives of this study are 1. To establish a prospective registry of the whole patients who received percutaneous coronary intervention with Resolute Onyx™ stent. 2.
- Conditions
- Coronary Artery Disease, Acute Coronary Syndrome, Myocardial Infarction, Angina Pectoris
- Trial name
- HOST-ONYX (NCT03151018)
- Testing
- Resolute Onyx
- Where
- 16 sites in South Korea
- Volunteers
- 4,000 people
- Sponsor
- Seoul National University Hospital
Infarction, Ischemia
CMR in the Assessment of Patient With ACS in the Emergency Room
In this study, we investigate the role of Cardiac Magnetic Resonance Imaging in patients with suspected, but not yet proven, "acute cardiac syndrome ACS".
- Conditions
- Infarction, Ischemia, Magnetic Resonance Imaging
- Trial name
- NCT00564382
- Testing
- Cardiac magnetic Resonance study
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- University of Calgary
Coronary Disease, Angina, Stable
Registry of RESOLUTE-ONYX™ Zotarolimus-eluting Stent Utilization in Percutaneous Small Vessel Coronary Interventionism.
DESIGN: Prospective, single-arm, multicenter, observational, prospective registry of the use of the RESOLUTE-ONYX™ zotarolimus-eluting stent in percutaneous coronary intervention in small vessels.
- Conditions
- Coronary Disease, Angina, Stable, Ischemia, Acute Coronary Syndrome
- Trial name
- Disco-9 (NCT04785846)
- Testing
- Percutaneous Coronary Intervention
- Where
- 15 sites in Spain
- Volunteers
- 307 people
- Sponsor
- Fundación Investigación Sanitaria en León
Cardiac Rehabilitation, Acute Coronary Syndrome
Mobile Tele-Monitoring Guided Cardiac Rehabilitation in Post-Acute Coronary Syndrome Patients
Cardiac rehabilitation (CR) programmes are effective measures to reduce recurrent ischemic events in post-acute coronary syndrome (ACS) patients.
- Trial name
- REHAB+ (NCT05207072)
- Where
- 4 sites in Netherlands, Spain
- Volunteers
- 900 people
- Sponsor
- Maastricht University
Coronary Artery Disease
Pre-hOspital Evaluation of Chest Pain Patients With sUspected Non ST-segment eLevation myocARdial Infarction Using the HEART-score With a Troponin Point-of-care Test
Overcrowding in the emergency department is an increasing problem in hospitals worldwide. Point-of-care Troponin (POC cTn) testing combined with a well investigated risk stratification tool (HEART-score) used in the ambulance may…
- Trial name
- POPular HEART (NCT04851418)
- Testing
- Possible NSTE-ACS
- Where
- 2 sites in Netherlands
- Volunteers
- 650 people
- Sponsor
- St. Antonius Hospital
Acute Coronary Syndrome, Myocardial Infarction
Cardiac Structure, Function, and Clinical Manifestations in MINOCA
The purpose of this study is to improve the differential diagnosis and clinical outcomes of acute coronary syndrome with non-obstructive coronary arteries, to investigate the relationship between the structural and functional…
- Trial name
- MINOCA (NCT03572023)
- Testing
- Integrative characterization of MINOCA patients, Characterization of MI patients with coronary obstruction
- Where
- Russia
- Volunteers
- 80 people
- Sponsor
- Tomsk National Research Medical Center of the Russian Academy of Sciences
Tako-Tsubo Cardiomyopathy, Stress-induced Cardiomyopathy
The TAKO-TSUBO And Cancer Registry
Prospective, multicenter, observational registry collecting data from subjects with Tako-Tsubo (stress-induced) cardiomyopathy (TTC).
- Conditions
- Tako-Tsubo Cardiomyopathy, Stress-induced Cardiomyopathy, Acute Coronary Syndrome
- Trial name
- TTAC (NCT01944826)
- Testing
- Registry of patients with Tako-Tsubo cardiomyopathy
- Where
- Germany
- Volunteers
- 800 people
- Sponsor
- Deutsches Herzzentrum Muenchen
Acute Myocardial Infarction, Acute Coronary Syndrome
Use of High Sensitivity Cardiac Troponin In Ruling Out Emergency Patients With Acute Myocardial Injury and Infarction
Examine the analytical and clinical performance of Atellica IM TnIH assay for the diagnosis and rule out of acute myocardial injury and myocardial infarction in patients presenting to the emergency department in whom serial cTnI…
- Trial name
- SAFETY (NCT04280926)
- Testing
- Cardiac Troponin Testing
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Fred Apple
Acute Coronary Syndrome, Myocardial Infarction
Efficacy of Preoperative Electrocardiography
A preoperative electrocardiogram (ECG) is nearly routinely performed by anesthesiologists in elderly non-cardiac surgery patients as part of pre-anesthesia evaluation.
- Conditions
- Acute Coronary Syndrome, Myocardial Infarction, Cardiac Arrest
- Trial name
- NCT00928460
- Testing
- Removal of preoperative electrocardiogram
- Where
- Netherlands
- Sponsor
- UMC Utrecht
Delirium
Incidence and Prognostic Value of Delirium in Patients With Acute Coronary Syndromes
The Purpose of this study is to evaluate the incidence of delirium in patients with acute coronary syndromes admitted to a Intensive Care Unit Patients.
- Trial name
- NCT02356523
- Testing
- Confusion Assessment Method
- Where
- Italy
- Volunteers
- 700 people
- Sponsor
- Ospedale San Donato
Symptomatic Decompensated Congestive Heart Failure, Congestive Heart Failure in Acute Coronary Syndrome
A Study Comparing Blood Flow and Clinical and Safety Effects of the Addition of Natrecor (Nesiritide), Placebo or Intravenous Nitroglycerin to Standard Care for the Treatment of Worsening Congestive Heart Failure.
The purpose of this study is to compare the hemodynamic (blood flow) and clinical effects of the study drug, Natrecor (nesiritide, a recombinant form of the natural human peptide normally secreted by the heart in response to…
- Trial name
- NCT00270374
- Testing
- nesiritide
- Volunteers
- 498 people
- Sponsor
- Scios, Inc.
Acute Coronary Syndrome
Treatment With Adenosine Diphosphate (ADP) Receptor Inhibitors: Longitudinal Assessment of Treatment Patterns and Events After Acute Coronary Syndrome
The TReatment with ADP receptor iNhibitorS: Longitudinal Assessment of Treatment Patterns and Events after Acute Coronary Syndrome (TRANSLATE-ACS) study is a prospective, observational longitudinal study to evaluate the real…
- Trial name
- TRANSLATE-ACS (NCT01088503)
- Testing
- ADP receptor inhibitors
- Where
- 186 sites in United States, Puerto Rico
- Volunteers
- 12,227 people
- Sponsor
- Eli Lilly and Company
Acute Coronary Syndrome, Coronary Artery Disease
Salts of Clopidogrel: Investigation to ENsure Clinical Equivalence
Clopidogrel besylate (CB) is not differentiated relative to the orignal clopidogrel hydrogen sulfate (CHS) in the pharmacokinetics and in antiplatelet potency in healthy volunteers.
- Conditions
- Acute Coronary Syndrome, Coronary Artery Disease, Ischemic Stroke, Peripheral Artery Disease
- Trial name
- SCIENCE (NCT02126982)
- Where
- Greece
- Volunteers
- 1,500 people
- Sponsor
- University of Ioannina
Arrhythmia, Acute Kidney Injuries
This is an Observational Study That Aims to Demonstrate Postoperative Risk Factors in Pediatric Cardiac Surgery
This retrospective observational study aims to identify risk factors for postoperative complications in children undergoing cardiac surgery at a tertiary hospital in Brazil.
- Conditions
- Arrhythmia, Acute Kidney Injuries, Sepsis, Pneumopathy
- Trial name
- PEDS-CARE (NCT06985082)
- Testing
- THERE IS NOT A INTERVENTION
- Volunteers
- 310 people
- Sponsor
- Instituto de Cardiologia do Rio Grande do Sul
Respiratory Distress Syndrome
Effect of Different Ventilatory Strategies on Cardiac Function in Patients With Acute Respiratory Failure
Mechanical ventilation with low tidal volume (about 6 ml.kg-1) reduces mortality in ALI/ARDS patients respect to high tidal volume ventilation (about 12 ml.kg-1).
- Trial name
- VITALI (NCT00713713)
- Testing
- Mechanical ventilation with low and high tidal volume
- Where
- Italy
- Volunteers
- 16 people
- Sponsor
- Fondazione Poliambulanza Istituto Ospedaliero
Dyspnea, Acute Heart Failure Syndrome
Precision of IMED-4 Lung Fluid Measurements
The purpose of this study is to determine if IMED-4 recordings have sufficient precision to detect a clinically significant change in lung fluid status in acute heart failure syndrome with pulmonary congestion.
- Conditions
- Dyspnea, Acute Heart Failure Syndrome, Pulmonary Congestion
- Trial name
- NCT02187770
- Testing
- IMED-4
- Where
- 3 sites in United States
- Volunteers
- 46 people
- Sponsor
- Intersection Medical, Inc.
Acute Heart Failure, Acute Coronary Syndrome
Heart Failure-USB: Prediction and Progression
This retrospective cohort study is to identify triggers of heart failure (HF) development and drivers of HF progression as well as the underlying cardiac disease (phenotype) to identify patients at risk and predict the clinical…
- Trial name
- HF-USB (NCT04000061)
- Testing
- medical chart review, data generated by direct IT export
- Where
- Switzerland
- Volunteers
- 6,000 people
- Sponsor
- University Hospital, Basel, Switzerland
Acute Respiratory Distress Syndrome
Evaluation of POC Lung Ultrasound Combined With Pressure-volume Curve to Titration Adjust PEEP for ARDS Lung Recruitment
Using lung ultrasound re-aeration score(LUS-RAS) combined with pressure-volume curve(PVC) adjust maintain positive end-expiratory pressure(PEEP) after recruitment maneuver, to achieve real-time adjustment, reduce…
- Trial name
- NCT03076450
- Testing
- Lung Ultrasound, Maximum Oxygenation
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Shanghai Pudong New Area Gongli Hospital
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