Clinical trials: Acute Cerebrovascular Accident
Hemiplegic Shoulder Pain, Stroke
Stroke Hemiplegic Shoulder Pain: Ultrasound Findings and VAS (Cross-Sectional)
Hemiplegic shoulder pain is a frequent complication after stroke and may be associated with structural abnormalities detectable by musculoskeletal ultrasound.
- Trial name
- NCT07426965
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Ankara Etlik City Hospital
Acute Stroke, Blood Pressure
Blood Pressure Target in Acute Stroke to Reduce hemorrhaGe After Endovascular Therapy
A randomized, multicenter study comparing two strategies: 1 / standard management of systolic blood pressure according to international recommendations (systolic blood pressure <185 mm Hg) versus 2 / intensive blood pressure…
- Conditions
- Acute Stroke, Blood Pressure, Cerebral Hemorrhage
- Trial name
- BP-TARGET (NCT03160677)
- Testing
- Systolic blood pressure target < 130 mm Hg, Systolic blood pressure target < 185 mm Hg
- Where
- 7 sites in France
- Volunteers
- 320 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Stroke, Ischemic
Resistive Diaphragmatic Breathing Exercise With Pursed Lips Breathing Exercise in Sub-acute Stroke Patients
To determine whether resistive diaphragmatic breathing exercise with pursed lips breathing exercise improve pulmonary function in sub-acute ischemic stroke, To determine whether resistive diaphragmatic breathing exercise with…
- Trial name
- NCT06326801
- Testing
- Resistive Diaphragmatic breathing exercise, Diaphragmatic breathing exercise, Conventional stroke physiotherapy
- Where
- Pakistan
- Volunteers
- 27 people
- Sponsor
- Riphah International University
Acute Stroke, Transient Ischemic Attack
Motivational Interviewing for Stroke
Motivational interviewing (MI) is a style of communication designed to elicit a person's own reasons for change to drive commitment toward a goal.
- Trial name
- NCT06195007
- Testing
- Motivational Interview
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of Florida
Acute Brain Injury, Extracorporeal Membrane Oxygenation Complication
ECMO ABI Detection With Hyperfine
The primary objective is to characterize the prevalence and type of ABI following cannulation for pediatric patients who require ECMO support.
- Conditions
- Acute Brain Injury, Extracorporeal Membrane Oxygenation Complication, Hypoxia-Ischemia, Brain, Stroke, Acute
- Trial name
- NCT06469801
- Testing
- Hyperfine
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Children's Mercy Hospital Kansas City
Acute Ischemic Stroke Patients, Large Vessel Occlusion
A Comparison of Cyclic Manual Direct Aspiration Thrombectomy (Plunger Technique) vs. Static Manual Direct Aspiration Thrombectomy for Treatment of Acute Large Vessel Occlusion Stroke
This prospective, randomized controlled trial will compare two manual aspiration techniques for treating acute ischemic stroke due to large vessel occlusion: cyclic aspiration (Plunger technique) and static aspiration.
- Trial name
- Plunger (NCT07231380)
- Testing
- Plunger Technique, Static Manual Aspiration Thrombectomy
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Vanderbilt University Medical Center
Stroke, Cardiovascular, Stroke, Acute
Stroke in Egyptian Clinical REgisTry
This is a multi-institutional registry database for the patients with stroke and cerebrovascular diseases. Stroke is the second leading cause of death in the Egypt.
- Conditions
- Stroke, Cardiovascular, Stroke, Acute, Stroke Hemorrhagic, Stroke Spinal Cord
- Trial name
- SECRET (NCT03723382)
- Testing
- SECRET structured 5 bundles of standard healthcare services
- Where
- Egypt
- Volunteers
- 50,000 people
- Sponsor
- Society of Minimally Invasive Neurological Therapeutic Procedures
Hypothermia, Stroke, Acute
Short-duration Selective Brain Cooling for Patients Undergoing Mechanical Thrombectomy
To determine the efficacy and safety of short-duration intra-artery selective brain cooling in addition to mechanical thrombectomy in patients with acute ischemic stroke.
- Trial name
- NCT03163459
- Testing
- selective brain cooling by cold saline perfusion, mechanical thrombectomy
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Capital Medical University
Acute Cerebrovascular Accident
Effect of Individualized Versus Standard Bp Management During MT for Anterior Ischemic Stroke
DETERMINE is a multicenter, prospective, randomised, open, blinded end-point assessed (PROBE) trial, to evaluate two approaches of blood pressure (BP) management during mechanical thrombectomy for acute ischemic stroke due to an…
- Trial name
- DETERMINE (NCT04352296)
- Testing
- Individualized blood pressure, Standard blood pressure
- Where
- France
- Volunteers
- 433 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Acute Ischemic Stroke, Artificial Intelligence (AI)
AI-Driven CTA Reconstruction for Intracranial LVO
Acute ischemic stroke (AIS) caused by intracranial large vessel occlusion (LVO) in the anterior circulation significantly contributes to stroke-related disability and mortality.
- Conditions
- Acute Ischemic Stroke, Artificial Intelligence (AI), Endovascular Thrombectomy, CT Angiography
- Trial name
- SMART-AI (NCT06645405)
- Testing
- AI algorithm
- Where
- 2 sites in China
- Volunteers
- 174 people
- Sponsor
- Shanghai Jiao Tong University Affiliated Sixth People's Hospital
Acute Ischemic Stroke
Transcranial Ultrasound in Clinical SONothrombolysis
This is a randomized, placebo controlled, parallel group dose escalation trial to evaluate the safety, tolerability, and activity of four sequential dose tiers of MRX-801 and ultrasound as an adjunctive therapy to tissue…
- Trial name
- TUCSON (NCT00504842)
- Testing
- MRX-801
- Where
- 14 sites in United States, France
- Volunteers
- 72 people
- Sponsor
- ImaRx Therapeutics
Acute Ischemic Stroke
Evaluation of Acute Endovascular Treatment in Symptomatic Isolated Cervical Internal Carotid Artery Occlusion (ETICA)
Our main hypothesis is that acute EVT associated with best medical treatment is superior to best medical treatment alone, for improving clinical outcomes at 90 days, in patients with mild or severe acute ischemique stroke and…
- Trial name
- ETICA (NCT05832762)
- Testing
- Endovascular treatment (EVT) + Best medical treatment (BMT), Best medical treatment (BMT)
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Montpellier
Stroke, Ischemic
LOTUS: Global Acute Stroke Study Utilizing Penumbra System
The primary objective of this study is to demonstrate safety and effectiveness of the Penumbra System in a population with acute ischemic stroke (AIS) secondary to intracranial large vessel occlusion (LVO).
- Trial name
- LOTUS (NCT04157270)
- Testing
- Penumbra System
- Where
- 2 sites in United States
- Volunteers
- 23 people
- Sponsor
- Penumbra Inc.
Stroke, Acute, Stroke, Ischemic
Endovascular Treatment With Versus Without Intravenous rhTNK-tPA in Stroke
The purpose of this trial is to investigate whether intravenous rhTNK-tPA prior to endovascular treatment can improve 90-day functional outcome of stroke patients with large vessel occlusion who are thrombolysis-eligible within…
- Trial name
- BRIDGE-TNK (NCT04733742)
- Testing
- rhTNK-tPA, Endovascular treatment
- Where
- 6 sites in China
- Volunteers
- 550 people
- Sponsor
- Xinqiao Hospital of Chongqing
Stroke, Atrial Fibrillation
Clinical Characteristics and Prognosis of Acute Cerebrovascular Events Secondary to Patients Receiving Cardiac Electronic Implants
To investigate the incidence, clinical characteristics and prognosis of acute ischemic and hemorrhagic cerebrovascular disease secondary to the implantation of cardiovascular implantable electronic devices, so as to provide a…
- Conditions
- Stroke, Atrial Fibrillation, Pacemaker
- Trial name
- SOS-CARE (NCT05623527)
- Testing
- cardiac electronic implants
- Where
- China
- Volunteers
- 13,324 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Acute Ischemic Stroke, ICAS - Intracranial Atherosclerosis
BASIS Technique for Endovascular Therapy of Acute Large Vessel Occlusion Strokes Due to Intracranial Atherosclerotic Disease
This study will explore the safety and efficacy of BASIS technology in ICAS-LVO lesions through a multicenter, prospective, registry, observational single-arm study.By registering intraoperative recanalization using this…
- Trial name
- NCT06881420
- Testing
- BASIS technique
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Fujian Medical University Union Hospital
Ischemic Stroke
Efficacy of Colchicine in Preventing Recurrent Stroke in the Patients With Acute Atherothrombotic Ischemic Stroke During Hospitalization
This study is two-center, prospective, randomized, open-label, controlled, investigator-sponsored study that aims to investigate the efficacy of low-dose colchicine in preventing recurrent stroke in the patients with acute…
- Trial name
- COLCHIDA (NCT06102720)
- Testing
- Colchicine, Clopidogrel
- Where
- 2 sites in Russia
- Volunteers
- 200 people
- Sponsor
- Mikhail Zykov
Acute Ischemic Stroke
The Efficacy and Safety of HRS-4029 in Acute Ischemic Stroke Patients
This trial will evaluate the efficacy and safety of HRS-4029 compared with placebo in participants with acute ischemic stroke (AIS).
- Trial name
- NCT07739160
- Testing
- HRS-4029
- Where
- China
- Volunteers
- 340 people
- Sponsor
- Beijing Suncadia Pharmaceuticals Co., Ltd
Stroke
Cord Blood Infusion for Ischemic Stroke
This is a phase one study investigating the safety of a single, intravenous infusion of banked allogeneic umbilical cord blood in subjects following an acute ischemic stroke.
- Trial name
- NCT02397018
- Testing
- allogeneic umbilical cord blood
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- Joanne Kurtzberg, MD
Acute Ischemic Stroke
Angong Niuhuang Pills With Different Bovine Bezoar Formulation Sources in the Treatment of AIS
This study is a single-center, open-label, controlled clinical trial that prospectively enrolls 100 participants (40 in the Z11020076 group, 40 in the Z20063878 group, and 20 in the blank control group) to collect clinical data…
- Trial name
- NCT06883110
- Testing
- Z11020076, Z20063878
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Tongji Hospital
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