Clinical trials: Acute Cerebrovascular Accident
Functionality, Spasticity, Muscle
Dry Needling in Stroke in Sub-Acute Phase to Improve Upper Limb
A single-center, observational, prospective, two dynamic cohorts study with before-after design. Group 1: Treatment with 6 sessions using dry needling with DNHS® (Dry Needling for Hypertonicity and Spasticity) on the spastic…
- Conditions
- Functionality, Spasticity, Muscle, Quality of Life
- Trial name
- NCT03462693
- Testing
- Dry needling
- Where
- Spain
- Volunteers
- 123 people
- Sponsor
- Guadarrama Hospital
Large Vessel Occlusion, Stroke Acute
Rescue Stenting and Intravenous Thrombolysis In Patients With Large Vessel Ischemic Stroke
Intravenous thrombolysis (IVT) and mechanical thrombectomy (MT) are the standard of care for treating selected patients with acute large-vessel occlusion stroke (LVOS).
- Conditions
- Large Vessel Occlusion, Stroke Acute, Thrombolysis, Rescue Stenting
- Trial name
- STARS (NCT06727006)
- Where
- 7 sites in Italy
- Volunteers
- 400 people
- Sponsor
- ASST Santi Paolo e Carlo
Acute Ischemic Stroke
Imaging Guided Patient Selection for Interventional Revascularization Therapy
The primary objective of this clinical evaluation is to determine the safety and effectiveness of the Penumbra System in a stroke cohort who presents within 8 hours from symptom and with a known core infarct volume at admission.
- Trial name
- START (NCT00963989)
- Testing
- Penumbra System
- Where
- United States
- Volunteers
- 146 people
- Sponsor
- Penumbra Inc.
Ischemic Stroke, Acute Coronary Syndrome
Comparative Study of Arterial Properties After an Ischaemic Stroke or an Acute Coronary Syndrome
A pilot, prospective, comparative study. To include both male and female patients who have presented an ischaemic stroke (full stroke or TIA) or an ACS, 5 to 30 days prior to inclusion.
- Conditions
- Ischemic Stroke, Acute Coronary Syndrome, Obstructive Sleep Apnea Syndrome
- Trial name
- AVC/SCA (NCT00926874)
- Where
- France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Grenoble
Acute Ischemic Stroke From Large Vessel Occlusion
HBO After Thrombectomy for AIS With LVO
The purpose of this RCT trial is to evaluate whether the sequential hyperbaric oxygen therapy can improve the 90-day functional outcome in patients with acute large vessel occlusion ischemic stroke after endovascular treatment.
- Trial name
- NCT07626450
- Testing
- Hyperbaric oxygen therapy plus standard medical treatment, Standard medical treatment
- Where
- China
- Volunteers
- 420 people
- Sponsor
- Beijing Tiantan Hospital
Stroke, Acute, Gait, Hemiplegic
Biomarkers of Independent Walking Post-Stroke
Prediction of walking recovery after stroke can inform patient-centered care and support discharge planning. The accuracy of current prediction models is limited, however, due to small study designs and narrow predictors…
- Trial name
- NCT05004389
- Testing
- MRI, blood draw, Clinical assessments
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of Vermont
Brain Infarction, Cerebral Ischemia
Intravenous Ancrod for the Treatment of Acute Ischemic Stroke Within 6 Hours After Onset of Symptoms
Treatment of acute stroke is still difficult and the only specific drug approved (rtPA) can only be administered if treatment starts within 3 hours after onset of symptoms.
- Conditions
- Brain Infarction, Cerebral Ischemia, Acute Stroke
- Trial name
- NCT00343174
- Testing
- Ancrod
- Sponsor
- Heidelberg University
Acute Ischemic Stroke, Stroke Recrudescence
Multilevel System Intervention Based on Information Platform to Reduce Ischemic Stroke Recurrence Rate
A prospective, multicenter and cluster randomised controlled trial will be conducted, using hospital as randomisation unit. Hospitals in Zhejiang Province, China, will be randomised into two arms (1:1): an intervention arm and a…
- Conditions
- Acute Ischemic Stroke, Stroke Recrudescence, Quality Improvement
- Trial name
- NCT05852080
- Testing
- multilevel system intervention based on information platform
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Sub-acute Stroke
Using Immersive Virtual Reality for the Upper Limb Rehabilitation of Post-stroke Subjects
Stroke produces brain damages that results in sensory, motor, and cognitive impairments which reduce the patient's quality of life and social participation.
- Trial name
- NCT06892886
- Testing
- Virtual Reality
- Where
- Italy
- Volunteers
- 48 people
- Sponsor
- University Hospital of Ferrara
Ischemic Stroke
Efficacy and Safety of LongShengZhi Capsule on Functional Recovery After Acute Ischaemic Stroke (LONGAN)
The aim of the study is to determine if LongShengZhi Capsule is effective and safe in patients with ischemic stroke in comparison to placebo.
- Trial name
- NCT05277311
- Testing
- LongShengZhi capsule
- Volunteers
- 1,376 people
- Sponsor
- Dongzhimen Hospital, Beijing
Ischemic Stroke
Safety of Transmucosal Capsaicin Sphenopalatine Ganglion Stimulation in Acute Ischemic Stroke
This study will evaluate the safety and tolerability of a dissolvable oral film containing a very small dose of capsaicin (the compound that produces the "hot" sensation in chili peppers) in adults with acute ischemic stroke.
- Trial name
- Cap-SPGAS (NCT07406971)
- Testing
- Capsaicin Transmucosal Oral Film
- Where
- Mexico
- Volunteers
- 46 people
- Sponsor
- Instituto Mexicano del Seguro Social
Stroke, Acute
Stroke and Rehabilitation in North of Norway and Central Denmark
Post-stroke prospective multicenter cohort study. The objectives of the study was to compare functioning and health related quality of life in the two study regions, in relation to known predictors and to differences in…
- Trial name
- NCT03948906
- Volunteers
- 815 people
- Sponsor
- University Hospital of North Norway
Stroke, Acute, Intracranial Hemorrhages
Safety, Tolerability and Pharmacokinetics of Y-2(Edaravone And Borneol) Sublingual Tablet
The primary objective is to evaluate the safety and tolerability of single ascending dose of Y-2 sublingual tablets in healthy male and female adult subjects.
- Trial name
- NCT03495206
- Testing
- Y-2(Edaravone And Borneol) Sublingual Tablet
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Yantai YenePharma Co., Ltd.
Stroke, Stroke, Acute
Gut Microbiota in Acute Stroke Patients
This study is to find out the significance of gut-microbiota in acute stroke patients, including their neurological, radiological outcomes as well as their stroke mechanisms.
- Conditions
- Stroke, Stroke, Acute, Stroke, Ischemic, Microbiome
- Trial name
- NCT03934021
- Where
- Hong Kong
- Volunteers
- 120 people
- Sponsor
- Chinese University of Hong Kong
Acute Stroke
Safety and Efficacy of Glibenclamide Combined With Rt-PA in Acute Cerebral Embolism
This study is designed to evaluate the safety and efficacy of oral glibenclamide in acute ischemic stroke patients who under intravenous rt-PA thrombolysis.
- Trial name
- SE-GRACE (NCT03284463)
- Testing
- Glibenclamide
- Where
- 8 sites in China
- Volunteers
- 306 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Cerebral Small Vessel Disease, Ischemic Stroke
Treatment of Acute Ischemic Stroke With Edaravone Dexborneol Sublingual Tablets in Small Vessel Disease
This study is a multicenter, randomized, double-blind, placebo-controlled trial designed to evaluate the efficacy and safety of Edaravone Dexborneol Sublingual Tablets in patients with acute ischemic stroke due to small vessel…
- Trial name
- TASTE-SVD (NCT06674460)
- Testing
- Edaravone Dexborneol Sublingual Tablets
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Peking Union Medical College Hospital
Stroke Acute
NeVa Retrospective Comparative SR Study
To compare safety and effectiveness of NeVa Stent Retriever (SR) to Control SR in the treatment of stroke caused by large vessel occlusion.
- Trial name
- NITRO (NCT06964724)
- Testing
- Mechanical thrombectomy
- Where
- 5 sites in Argentina, Belgium and 3 more
- Volunteers
- 800 people
- Sponsor
- Vesalio
Acute Ischemic Stroke
Tenecteplase Reperfusion Therapy in Acute Ischemic Cerebrovascular Events-Ⅱ
A Phase Ⅲ, Multicenter, Prospective, Randomized, Open Label, Blinded-endpoint (PROBE) Controlled Trial of Recombinant Human TNK Tissue-type Plasminogen Activator (rhTNK-tPA) for Injection Versus Alteplase for Acute Ischemic…
- Trial name
- TRACEⅡ (NCT04797013)
- Testing
- rt-PA, rhTNK-tPA
- Where
- 61 sites in China
- Volunteers
- 1,430 people
- Sponsor
- Beijing Tiantan Hospital
Stroke, Acute, Venous Thromboembolism
GEKO Venous Thromboembolism Prevention Study
This multicentre, randomised geko™ venous thromboembolism (VTE) prevention study will prospectively collect clinical data on VTE occurrences in immobile patients after stroke, who will be randomised, on a 1:1 allocation, to…
- Conditions
- Stroke, Acute, Venous Thromboembolism, Deep Vein Thrombosis, Pulmonary Embolism
- Trial name
- NCT05476913
- Testing
- geko™ device
- Where
- 18 sites in United Kingdom
- Volunteers
- 1,200 people
- Sponsor
- Firstkind Ltd
Stroke, Acute Ischemic Stroke
Intravenous Thrombolysis in Acute Ischemic Stroke with Active Cancer
The primary hypothesis being tested in this trial is that ischemic stroke patients with active cancer will have improved clinical outcomes when given intravenous thrombolysis compared to standard care.
- Trial name
- NCT06841965
- Testing
- Intravenous thrombolysis
- Volunteers
- 280 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.