Clinical trials: Acute Cerebrovascular Accident
Stroke, Post-Stroke Cognitive Impairment
Immune-Inflammatory Biomarkers in Predicting Early Cognitive Impairment in Adults With Acute Basal Ganglionic Stroke
Post-stroke cognitive impairment (PSCI) is a common and disabling complication that affects memory, thinking, and daily functioning after a stroke.
- Conditions
- Stroke, Post-Stroke Cognitive Impairment, Ischemic Stroke, Intracerebral Hemorrhage
- Trial name
- NCT07837466
- Volunteers
- 100 people
- Sponsor
- Assiut University
Stroke
The Correlation Between the Length of Stay in Post Acute Care(PAC) and General Improvements in Stroke Patients
Post-Acute Care(PAC) had been inaugurated in Taiwan for almost four years and current essays revealed positive effects upon general improvements in stroke patient after PAC training.
- Trial name
- NCT03778905
- Testing
- Rehabilitation
- Where
- Taiwan
- Volunteers
- 305 people
- Sponsor
- Chimei Medical Center
Ischemic Stroke
Predictors and Prognostic Factors on the Acute Ischemic Stroke
Through 5 years continuous observation of acute ischemic stroke patients in Neurology Department of Tongji Hospital, Tongji Medical College of Huazhong University of Science and Technology, clinical data about emergency treatment…
- Trial name
- NCT03122002
- Testing
- Drug Therapy, Routine Blood Test and Image Scan, Intravascular therapy
- Where
- China
- Volunteers
- 1,200 people
- Sponsor
- Tongji Hospital
Stroke Inflammation
Fingolimod in Endovascular Treatment of Ischemic Stroke
Proof-of concept clinical trials have indicated that the sphingosine-1-phosphate receptor modulator fingolimod may be efficacious in attenuating brain inflammation and improving clinical outcomes in patients with acute ischemic…
- Trial name
- NCT04629872
- Testing
- Fingolimod
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Ning Wang, MD., PhD.
Acute Ischemic Stroke
Acute Ischemic Stroke Registry for Endovascular Treatment
The Acute Ischemic Stroke Registry for Endovascular Treatment (AIS-EVT) is an academic, prospective, multicenter, observational registry study.
- Trial name
- NCT05213754
- Testing
- Endovascular Treatment
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Capital Medical University
Ischemic Stroke
Total Posterior-circulation Infarct Volume in Basilar Artery Stroke
Preprocedural predictors of outcome in patients with acute basilar artery occlusion (ABAO) who underwent endovascular treatment (EVT) remain controversial.
- Trial name
- TPCIV-ABAO (NCT04650022)
- Testing
- Mechanical thrombectomy
- Where
- France
- Volunteers
- 110 people
- Sponsor
- University Hospital, Montpellier
Stroke
Study to Enhance Motor Acute Recovery With Intensive Training After Stroke
Stroke often results in limitation of arm movements, from which many people do not fully recover. We believe that early and intensive therapy is important to enhance recovery of arm movements after stroke.
- Trial name
- SMARTS2 (NCT02292251)
- Testing
- Device-assisted therapy, Therapy-based occupational therapy
- Where
- 3 sites in United States, Switzerland
- Volunteers
- 32 people
- Sponsor
- Johns Hopkins University
Acute Stroke
Effect of Music Listening on Stress in Acute Stroke
Investigation on changes in the neurochemical stress parameters in acute stroke. 30 patients are recruited in the stroke unit, blood samples are collected at fixed intervals during the first two days.
- Trial name
- MUKU3-1 (NCT05859841)
- Testing
- Music listening, Control
- Where
- Finland
- Volunteers
- 32 people
- Sponsor
- Turku University Hospital
Stroke, Acute, Stroke
Treatments for Recovery of Hand Function in Acute Stroke Survivors
Impaired hand function is one of the most frequently persisting consequences of stroke. The purpose of this study is to investigate whether two different types of treatment improve recovery of hand function after stroke.
- Conditions
- Stroke, Acute, Stroke, Hemiparesis, Hemiplegia
- Trial name
- NCT00565045
- Testing
- Neuromuscular electrical stimulator
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- MetroHealth Medical Center
Acute Ischemic Stroke
EndovaSCular TreAtment to imProve outcomEs for Medium Vessel Occlusions (ESCAPE-MeVO Trial)
Stroke occurs when a blood clot causes a blockage in a blood vessel (artery) within the brain. This type of stroke is called an ischemic stroke and carries a high risk of disability or death. Stroke must be treated very fast.
- Trial name
- ESCAPE-MeVO (NCT05151172)
- Testing
- endovascular thrombectomy (EVT), Standarad medical care
- Where
- 53 sites in United States, Canada and 2 more
- Volunteers
- 530 people
- Sponsor
- Dr. Michael D Hill
Acute Ischemic Stroke
BXOS110 Injection in the Treatment of Acute Ischaemic Stroke
The purpose of this study was to evaluate the effectiveness of early administration of BXOS110 for injection in reducing overall disability in patients with acute ischaemic stroke.
- Trial name
- NCT06322394
- Testing
- high-dose BXOS110, low-dose BXOS110
- Where
- 24 sites in China
- Volunteers
- 300 people
- Sponsor
- Biocells (Beijing) Biotech Co.,Ltd
Stroke
Edaravone and Argatroban Stroke Therapy Study for Acute Ischemic Stroke
Edaravone, a free radical scavenger, is a novel neuroprotective agent, and argatroban is a selective thrombin inhibitor. Both the drugs were approved by the Japanese Government, and have frequently been used for the treatment of…
- Trial name
- EAST (NCT00153946)
- Testing
- Edaravone
- Where
- Japan
- Volunteers
- 814 people
- Sponsor
- Combination Therapy for Acute Ischemic Stroke Study Group
Acute Ischemic Stroke, Blood Pressure Variability
Blood Pressure Variability and Ischemic Stroke Outcome
The goal of this observational study is to evaluate the role of blood pressure (BPV) variability in patients suffering from acute ischemic stroke. The main questions it aims to answer are: 1.
- Trial name
- BP-VISO (NCT05756257)
- Where
- 3 sites in United States
- Volunteers
- 150 people
- Sponsor
- Yale University
Acute Ischemic Stroke AIS
A Phase IIa Clinical Trial to Evaluate the Efficacy and Safety of Intravenous Infusion of hUC-MSCs in Patients With AIS
This is a Phase IIa clinical trial with a three-arm design that utilizes randomization, double-blinding, and placebo control. The primary objective of this study is to evaluate the efficacy of single and multiple intravenous…
- Trial name
- NCT07084012
- Testing
- hUC-MSCs treatment (high dose), hUC-MSCs treatment (low dose)
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Shenzhen Wingor Biotechnology Co., Ltd.
Cerebral Small Vessel Diseases, Cerebral Small Vessel Ischemic Disease
Testing of a System for Remote Ischemic Conditioning in Cerebral Small Vessel Disease and Pre-hospital Stroke Care
This early phase trial will address the following key objectives: 1. Completion of initial safety and tolerability testing of our viable prototype for remote ischemic conditioning (RIC) with patients with (a) CSVD and (b) acute…
- Conditions
- Cerebral Small Vessel Diseases, Cerebral Small Vessel Ischemic Disease, Ischemic Stroke, Vascular Cognitive Impairment
- Trial name
- TRIC-SVD (NCT05967728)
- Testing
- Remote ischemic conditioning (RIC) progammable device
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- University of Calgary
Dysphagia Following Cerebral Infarction, Dysphagia Following Nontraumatic Intracerebral Hemorrhage
Validation and Reliability Testing of Dysphagia Trained Nurse Assessment
Nurses at Royal Derby Hospital, UK have been trained to use a comprehensive protocol based dysphagia assessment (Dysphagia Trained Nurse Assessment (DTNAx)) to assess all acute stroke patients on admission.
- Trial name
- NCT03700853
- Testing
- Dysphagia Trained Nurse Assessment (DTNAx)
- Where
- United Kingdom
- Volunteers
- 47 people
- Sponsor
- University of Nottingham
Stroke, Stroke, Acute
Evaluation of the Use of the Atalante Exoskeleton in Patients Presenting an Hemiplegia Due to Cerebrovascular Accident
The INSPIRE study is interventional, European, prospective, open, multicentric, each patient being his/her own control. It is conducted to assess the safety and performance of the Atalante exoskeleton system in patients…
- Conditions
- Stroke, Stroke, Acute, Stroke, Subacute, Chronic Stroke
- Trial name
- INSPIRE (NCT04694001)
- Testing
- Use of the Atalante exoskeleton
- Where
- 6 sites in Belgium, France and 1 more
- Volunteers
- 40 people
- Sponsor
- Wandercraft
Stroke, Acute Ischemic Stroke
The MRI-based Evaluation of Safety and Efficacy of EVT and SMT: A Retrospective, Multicenter Study
Acute Basilar Artery Occlusion (ABAO), a condition with a high risk of mortality or disability (up to 80%). The safety and efficacy of endovascular thrombectomy (EVT) in ABAO remains uncertain due to inconsistent evidence from…
- Conditions
- Stroke, Acute Ischemic Stroke, Ischemic Stroke
- Trial name
- NCT06236828
- Testing
- Mechanical Thrombectomy
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Xuanwu Hospital, Beijing
Hemiplegia, Stroke
Mirror vs Virtual Reality Therapy for Upper Extremity Function in Hemiplegic Patients
Upper extremity impairment in hemiplegic patients significantly impacts daily activities and reduces quality of life. Although traditional rehabilitation methods can help, some patients experience limited progress.
- Conditions
- Hemiplegia, Stroke, Upper Extremity Dysfunction
- Trial name
- NCT07018336
- Testing
- Mirror Therapy, Virtual Reality (VR) Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Istinye University
Stroke
Post-marketing Clinical Study of Alteplase for Acute Ischemic Stroke （Japan Alteplase Clinical Trial Ⅱ：J-ACT Ⅱ）
The purpose of this study is to confirm the efficacy and safety of intravenously administered alteplase in patients with acute ischemic stroke based on the rate of recanalization assessed by magnetic resonance angiography (MRA)…
- Trial name
- NCT00412867
- Testing
- Alteplase
- Where
- Japan
- Volunteers
- 58 people
- Sponsor
- Tanabe Pharma Corporation
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