Clinical trials: Acute Cerebrovascular Accident
Stroke, Acute
Thrombectomy In ANdalucia Using Aspiration (TRIANA)
This study aims to compare the efficacy and safety of ADAPT vs Stentriever techique in a multicenter stroke cohort of patients.
- Trial name
- TRIANA (NCT03407092)
- Testing
- ADAPT cohort, Stentriever Cohort
- Where
- Spain
- Volunteers
- 532 people
- Sponsor
- Hospitales Universitarios Virgen del Rocío
Chronic Kidney Disease, Acute Bleeding
The Strategy to Prevent Hemorrhage Associated With Anticoagulation in Renal Disease Management (STOP HARM) Trial
Patients with severe chronic kidney disease (CKD) who develop atrial fibrillation are at high risk for stroke. The use of blood thinking medication in dialysis patients is controversial and warfarin carries a serious risk for…
- Conditions
- Chronic Kidney Disease, Acute Bleeding, Cerebrovascular Stroke
- Trial name
- STOP-HARM (NCT02885545)
- Testing
- Watchman, Continued therapy with the prescribed oral anticoagulant
- Where
- Canada
- Sponsor
- Population Health Research Institute
Stroke
Association of Osmotic Drugs With Clinical Outcomes in Acute Large Hemispheric Infarction
Stroke remains the second leading cause of death worldwide, with 2%-8% of these being large hemispheric infarction (LHI) with an occupying effect and the worst prognosis.
- Trial name
- NCT05914272
- Testing
- Osmotic drugs
- Where
- 19 sites in China
- Volunteers
- 2,592 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Acute Coronary Syndrome
Veliflapon (DG-031)to Prevent Heart Attacks or Stroke in Patients With a History of Heart Attack or Unstable Angina
The purpose of this study is to determine if veliflapon (DG-031)can prevent a heart attack or stroke in African American patients with a history of unstable angina or myocardial infarction.
- Trial name
- NCT00353067
- Testing
- veliflapon (DG-031)
- Where
- 11 sites in United States
- Volunteers
- 3,450 people
- Sponsor
- deCODE genetics
Stroke
Study of the Performance of Stroke Management in the Rhône Area
Acute stroke management represents a true medical emergency that requires prompt diagnosis and urgent treatment. However, only a small percentage of patients access to thrombolysis on time.
- Trial name
- STROKE 69 (NCT02596607)
- Where
- 7 sites in France
- Volunteers
- 3,454 people
- Sponsor
- Hospices Civils de Lyon
Acute Stroke
Intravenous Autologous Bone Marrow-derived Stem Cells Therapy for Patients With Acute Ischemic Stroke
A multi-centric initiative to study safety,feasibility and efficacy of using intravenous autologous bone marrow mononuclear cells(BMMC) in patients with acute ischemic stroke.This phase of study is visualised as phase 2 study and…
- Trial name
- NCT01501773
- Testing
- Autologous bone marrow stem cell
- Where
- 5 sites in India
- Volunteers
- 120 people
- Sponsor
- Manipal Acunova Ltd.
Acute Ischemic Stroke AIS
Exploration of the Efficacy and Mechanism of Galantamine (an Extract From Lycoris Aurea) in Treating Ischemic Stroke
Although mechanical thrombectomy or thrombolytic therapy for large vessels can achieve a revascularization rate (TICI ≥2b) of over 90%, 30-50% of patients still exhibit poor functional outcomes.
- Trial name
- NCT07003386
- Testing
- Galantamine, Standard treatment for acute ischemic stroke
- Where
- China
- Volunteers
- 66 people
- Sponsor
- Shanghai Yueyang Integrated Medicine Hospital
Stroke, Thrombectomy
Results of the Use of Two Stentrievers Simultaneosly Compared With One as a Primary Treatment in Acute Ischemic Stroke
Several studies have demonstrated that simultaneous treatment with two stentrievers (STs) as rescue treatment is very effective, with high recanalization rates even in this group of patients where other revascularization…
- Conditions
- Stroke, Thrombectomy, Arterial Occlusive Diseases
- Trial name
- DIVERSO (NCT05930145)
- Testing
- Double stentriever, Single stentriever
- Where
- 4 sites in Germany, Spain
- Volunteers
- 200 people
- Sponsor
- Fundación EPIC
Acute Ischemic Stroke
Heart Evaluation of Acute Ischemic Stroke With Reperfusion Therapy
Heart Evaluation of Acute ischemic stroke with Reperfusion Therapy (HEART) is a single-center observational registry evaluating the heart of patients hospitalized for acute ischemic stroke with reperfusion therapy.
- Trial name
- HEART (NCT06882577)
- Testing
- observational only- no intervention
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Soochow University
Stroke, Acute
Exploring Motor Learning in Acute Stroke Through Robotics
The acute phase of stroke is characterized by an enhancement of neural plasticity which supports rapid motor recovery. It is unclear whether acute stroke patients can acquire new motor skills with their affected upper limb.
- Trial name
- NCT04171856
- Testing
- REAplan(R)
- Where
- 2 sites in Belgium
- Volunteers
- 245 people, healthy volunteers welcome
- Sponsor
- University Hospital of Mont-Godinne
Ischemic Stroke, Neuromuscular Electrical Stimulation
Neuromuscular Electrical Stimulation in Acute Ischemic Stroke
The purpose of the study is to examine the added effect of NeuroMuscular Electric Stimulation (NMES) in addition to exercise therapy in the acute phase of ischemic stroke.
- Conditions
- Ischemic Stroke, Neuromuscular Electrical Stimulation, Exercise
- Trial name
- NESA (NCT03653312)
- Testing
- NMES
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- Zealand University Hospital
Stroke Acute, Stroke (CVA) or Transient Ischemic Attack
Evaluating the Effect of Nurse-Led Stroke Transitional Care in Tanzania
The goal of this observational study is to assess the effects of nurse-led stroke transitional care in stroke survivors, caregivers and healthcare providers who participate in nurse-led stroke transitional care program to improve…
- Trial name
- NCT07319312
- Testing
- Nurse-led stroke transitional care program
- Where
- Tanzania
- Volunteers
- 130 people
- Sponsor
- Shandong University
Stroke, Acute, Cognitive Dysfunction
Validity and Reliability of a Self-evaluation Tool for Cognitive Deficits in the Acute Stage After Stroke
Cognitive disorders are common early after stroke but can be overseen in patients with mild stroke who seem to be functionally recovered but are at risk to experience difficulties in advanced daily activities affecting social…
- Trial name
- NCT04624529
- Testing
- Self evaluation tool
- Where
- Belgium
- Volunteers
- 44 people
- Sponsor
- KU Leuven
Stroke, Ischemic, Stroke, Acute
Efficacy of Cerebrolysin Treatment as an add-on Therapy to Mechanical Thrombectomy in Acute Ischemic Stroke.
This study is designed to determine the efficacy and safety of Cerebrolysin treatment as an add- on therapy to mechanical thrombectomy (MT) in reducing global disability in subjects with acute ischemic stroke (AIS).
- Conditions
- Stroke, Ischemic, Stroke, Acute, Stroke Sequelae
- Trial name
- NCT04904341
- Testing
- Cerebrolysin
- Where
- Poland
- Volunteers
- 50 people
- Sponsor
- Military Institute od Medicine National Research Institute
Stroke, Spastic Hemiplegia
Robot-assisted Versus Conventional Physical Therapy for Hand in Sub-acute Stroke
This randomized controlled trial aims to compare the effectiveness of robotic-assisted physiotherapy and conventional physiotherapy in improving hand function among patients with sub-acute stroke.
- Conditions
- Stroke, Spastic Hemiplegia, Upper Limb Motor Impairment
- Trial name
- ROCHAS (NCT07615569)
- Testing
- Robotic-Assisted Hand Rehabilitation Therapy, Conventional Physiotherapy
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Montiha Azeem
Ischemic Stroke, Migraine
Sensitivity to Acute Cerebral Ischemia in Migrainers
Sensitivity to Acute Middle cerebral or intracranial Carotid artery Occlusion in MIGrainers (SMCO-MIG) is a prospective multi-center study to determine if migraine induces a faster infarct growth as assessed by initial multimodal…
- Conditions
- Ischemic Stroke, Migraine, Migraine With Aura
- Trial name
- SAMCO-MIG (NCT03301441)
- Testing
- questionnaire ef-ID Migraine
- Where
- France
- Volunteers
- 605 people
- Sponsor
- University Hospital, Montpellier
Type 2 Diabetes, Heart Failure, Reduced Ejection Fraction
Acute and Chronic Effects of Oral Ketones in Subjects With HFrEF and Diabetes
This study will provide insight into whether cardiac function changes with oral Ketone Esters (KE) administered to patients with Type 2 Diabetes Mellitus (T2DM) and Heart failure with reduced ejection fraction (HFrEF).
- Trial name
- NCT06108076
- Testing
- Ketone Monoester (KE)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Acute Ischemic Stroke
Thrombectomy Using Pulsed Aspiration for Reperfusion of Brain Occlusions
The goal of this clinical trials is to demonstrate the safety and effectiveness for the RapidPulseTM Aspiration System in patients experiencing acute ischemic stroke within 8 hours of symptom onset or last seen normal.
- Trial name
- TURBO (NCT06029491)
- Testing
- RapidPulseTM Aspiration System
- Where
- 30 sites in United States, France and 2 more
- Volunteers
- 170 people
- Sponsor
- RapidPulse, Inc
Stroke
Comparative Evaluation of Stroke Triage Algorithms for Emergency Medical Dispatchers
This study will compare the diagnostic accuracy of Card 28 stroke protocol to Card 28 and Cincinnati Stroke Scale, when used by emergency medical dispatchers to interrogate a 911 call suggestive of stroke.
- Trial name
- MeDS (NCT01202318)
- Where
- United States
- Sponsor
- University of California, San Francisco
Acute Ischemic Stroke
Concentric Retriever Device (CRD) in Acute Ischemic Stroke
The primary purpose is to study the safety and effectiveness of the Concentric Retriever Device(CRD)in ischemic stroke patients who undergo clot retrieval with the CRD within 8 hours of stroke symptom onset.
- Trial name
- NCT00203710
- Testing
- Concentric Retriever Device
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Sidney Starkman
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