Clinical trials: Acute Conditions
Acute Myocardial Infarction With ST Elevation
Effect of Glp-1 and Antidiabetic sgLT2 Agents for myoCardial infarcTion and Ultrasensitive Inflammatory Surveillance (GALACTUS Trial)
The primary risk factor for coronary artery disease is atherosclerosis, with inflammation playing a crucial role in the development and progression of this condition.
- Trial name
- GALACTUS (NCT07295223)
- Testing
- Dapagliflozin 10 MG Oral Tablet, Semaglutide (Rybelsus®)
- Where
- Mexico
- Volunteers
- 44 people
- Sponsor
- Instituto Mexicano del Seguro Social
Acute Coronary Syndrome, NSTEMI - Non-ST Segment Elevation MI
Safety of Accelerated Rule-out Protocols in Patients Admitted With Chest Pain to a Crowded Chest Pain Unit (CPU)
The aim of this observational study registry is to assess the safety of a Non-ST-elevation myocardial infarction (STEMI) rapid rule-out strategy as proposed by European Guidelines in patients presenting with suspected acute…
- Trial name
- NCT03111862
- Testing
- NSTEMI Rule-Out according to hs-TnT
- Where
- Germany
- Volunteers
- 3,567 people
- Sponsor
- University Hospital Heidelberg
Hyperglucagonemia, Obesity
Effects of Glucagon Administration on Energy Expenditure
The purpose of this study is to collect data to help researchers better understand the effects of glucagon on the amount of calories burned.
- Trial name
- GLEE (NCT02237053)
- Testing
- Glucagon, Octreotide, Insulin
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- AdventHealth Translational Research Institute
Obese Individuals, Central Adiposity
Post-exercise Blood Pressure With Inorganic Nitrate
This study is examining whether acute inorganic nitrate supplementation in the form of beetroot juice, paired with an acute bout of exercise, affects blood pressure and what is the magnitude of the difference compared to exercise…
- Trial name
- BEET-DOWN (NCT07869472)
- Testing
- Beetroot Juice - Active + Exercise, Beetroot Juice - Active + No exercise
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Acute Coronary Syndrome
Assessment of Biomarkers for Diagnosis in Geriatric Patients
Elderly patients are often admitted to hospital because of chest pain that is atypical for angina pectoris. In case of inconclusive electrocardiograms, determination of troponin is important for the diagnosis of an acute coronary…
- Trial name
- BOSCH1 (NCT01370395)
- Where
- Germany
- Volunteers
- 250 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome, Chronic Myelomonocytic Leukemia
Liposome-encapsulated Daunorubicin-Cytarabine and Gemtuzumab Ozogamicin in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia (AML) or High Risk Myelodysplastic Syndrome
This phase II trial studies the side effects and how well liposome-encapsulated daunorubicin-cytarabine and gemtuzumab ozogamicin work in treating patients with acute myeloid leukemia that has come back (relapsed) or that does…
- Conditions
- Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome, Chronic Myelomonocytic Leukemia, High Risk Myelodysplastic Syndrome, Myelodysplastic Syndrome
- Trial name
- NCT03672539
- Testing
- Gemtuzumab Ozogamicin, Liposome-encapsulated Daunorubicin-Cytarabine, Quality-of-Life Assessment
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- M.D. Anderson Cancer Center
Long Haul COVID, Postural Orthostatic Tachycardia Syndrome
Ivabradine for Long-Term Effects of COVID-19 With POTS Cohort
The purpose of the study is three-fold. The primary aim is to identify the proportion of Long-Haul COVID (LHC) and non-LHC volunteers with relevant symptoms actually have postural orthostatic tachycardia syndrome (POTS).
- Trial name
- COVIVA (NCT05481177)
- Testing
- Ivabradine
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Uniformed Services University of the Health Sciences
Atherosclerosis, Acute-Phase Reaction
Erythrocyte-Mediated Drug Delivery for the Prevention of Stent Restenosis
The purpose of this study is to determine whether erythrocyte mediated dexamethasone delivery reduces circulating inflammatory markers after coronary stent implantation and improves clinical and angiographic outcomes.
- Trial name
- TROY (NCT00484965)
- Testing
- Coronary stenting
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- University of Rome Tor Vergata
Sudden Cardiac Death, Acute Myocardial Infarction
Thrombus and Inflammation Study in Sudden Cardiac DEath
Sudden death is a natural death occurring within one hour after the onset of symptoms. It remains a major public health problem and accounts for 5 to 10 % of the annual total mortality ie about 300.000 in the United States.
- Trial name
- TIDE (NCT00748111)
- Testing
- Blood sample
- Where
- France
- Volunteers
- 380 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Myocardial Infarction
Acute Myocardial Infarction by Penetrating Cardiac Trauma
Patients with a cardiac stab wound could be complicated by a posttraumatic acute myocardial infarction (PAMI). Traditionally, the investigators can explain it by the occlusion of a coronary artery; but the PAMI isn´t constantly…
- Trial name
- NCT01182064
- Where
- Colombia
- Volunteers
- 51 people
- Sponsor
- Universidad de Antioquia
Stroke, Cerebrovascular Disorders
Intra-arterial Thrombolysis for Acute Ischemic Stroke With Medium Vessel Occlusion
Acute ischemic stroke (AIS) due to medium vessel occlusion (MeVO) or severe stenosis poses a significant clinical challenge. Recent large randomized controlled trials, DISTAL and ESCAPE-MeVO, demonstrated no significant benefit…
- Conditions
- Stroke, Cerebrovascular Disorders, Brain Diseases, Nervous System Diseases
- Trial name
- RESCUE MeVO (NCT07185022)
- Testing
- Intra-arterial Thrombolysis, Best Medical Treatment
- Where
- 6 sites in China
- Volunteers
- 282 people
- Sponsor
- The Second Hospital of Anhui Medical University
Gastric Variceal Hemorrhage
N-Butyl-2-Cyanoacrylate Injection Versus Band Ligation for Gastric Variceal Hemorrhage
The purpose of this study was to test the hypothesis by comparing the efficacy of cyanoacrylate injection (GVO) and band ligation (GVL) in the treatment of acute GVH in liver cirrhotic patients with or without concomitant…
- Trial name
- NCT00292331
- Testing
- cyanoacrylate injection to treat gastric variceal hemorrhage
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Acute Respiratory Distress Syndrome, Corona Virus Infection
Knowledge, Attitude and Practice of Dental Students About COVID-19
Coronavirus disease 2019 (abbreviated "COVID- 19") is a pandemic respiratory disease that is caused by a novel coronavirus and was first detected in December 2019 in Wuhan, China.
- Conditions
- Acute Respiratory Distress Syndrome, Corona Virus Infection, Acute Lung Injury, Fever
- Trial name
- NCT04449081
- Testing
- Knowledge, Attitude, Practice, Awareness, Preference
- Where
- Malaysia
- Volunteers
- 215 people, healthy volunteers welcome
- Sponsor
- Melaka Manipal Medical College
Consciousness Disorder
Outcome Prediction in Patients With Acute Disorders of Consciousness
Prior research has indicated a link between outcomes in patients with disorders of consciousness (DOC) and their responses to emotional auditory stimuli.
- Trial name
- NCT04411719
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Zhejiang University
Wound Infection, Abscess
Oritavancin Versus IV Vancomycin for the Treatment of Participants With Acute Bacterial Skin and Skin Structure Infection (SOLO I)
The purpose of this Phase 3 trial was to evaluate the efficacy, safety, and tolerability of oritavancin in acute bacterial skin and skin structure infections (ABSSSIs), including those caused by methicillin-resistant…
- Conditions
- Wound Infection, Abscess, Systemic Inflammation, Cellulitis
- Trial name
- SOLO I (NCT01252719)
- Testing
- Single-Dose IV Oritavancin Diphosphate, IV Vancomycin
- Where
- United States
- Volunteers
- 968 people
- Sponsor
- Melinta Therapeutics, Inc.
Non ST Segment Elevation Myocardial Infarction, Unstable Angina
Patients With High-risk Acute Coronary Syndrome Without ST-segment Elevation
This non-inferiority study aims at comparing Versa® to the reference enoxaparin (Clexane®, Sanofi-Aventis) in patients with high-risk unstable angina and NSTEMI.
- Trial name
- VECOR (NCT01356992)
- Testing
- Enoxaparin
- Where
- 5 sites in Brazil
- Volunteers
- 62 people
- Sponsor
- Eurofarma Laboratorios S.A.
B Acute Lymphoblastic Leukemia, Minimal Residual Disease
Pembrolizumab in Treating Minimal Residual Disease in Patients With Acute Lymphoblastic Leukemia
This phase II trial studies how well pembrolizumab works in treating small amounts of cancer cells that remain after attempts to remove the cancer has been made in patients with acute lymphoblastic leukemia.
- Conditions
- B Acute Lymphoblastic Leukemia, Minimal Residual Disease, Recurrent Acute Lymphoblastic Leukemia, T Acute Lymphoblastic Leukemia
- Trial name
- NCT02767934
- Testing
- Laboratory Biomarker Analysis, Pembrolizumab
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Washington
Arthropathy Shoulder, Pain, Acute
CORA-Q15: Continuous vs. Single-injection Interscalene Block on QoR-15 in Outpatient Rotator Cuff Surgery
The purpose of the study will be to compare the efficacy of single-injection interscalene block versus continuous interscalene block on the quality of recovery in patients undergoing outpatient arthroscopic rotator cuff repair…
- Conditions
- Arthropathy Shoulder, Pain, Acute, Anesthesia
- Trial name
- CORA-Q15 (NCT06754657)
- Testing
- Continuous perineural infusion, Single injection
- Where
- Chile
- Volunteers
- 150 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia
Open-label Clinical Trial to Investigate the Safety and Tolerability of Allogeneic B-cell Concentrates for Immune Reconstitution After Allogeneic Stem Cell Transplantation Measured as Response to a Antedated Single Vaccination
The reconstitution of a functioning immune system after allogeneic stem cell transplantation takes months to years. Particularly memory B-lymphocytes reconstitute poorly with the current conditioning regimes.
- Conditions
- Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Chronic Myeloid Leukemia, Non Hodgkin's Lymphoma
- Trial name
- B-cell therapy (NCT02007811)
- Testing
- allogeneic donor derived B-lymphocytes
- Where
- Germany
- Volunteers
- 15 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Neuromuscular Manifestations
Effects of Static Stretching and Dynamic in Flexibility and Performance: Blind and Randomized Clinical Trial
The purpose of this study is analyze the effects, acute and chronic, static and dynamic stretching on flexibility and neuromuscular and functional performance in active, healthy individuals. Study hypothesis: 1.
- Trial name
- NCT02689544
- Testing
- intervention with static stretching, intervention with Dynamic Stretching, Control
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Germanna de Medeiros Barbosa
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.