Clinical trials: Acute Coronary Event
Acute Myocardial Infarction, Ventricular Tachycardia
Acute Cardiovascular Events Triggered by COVID-19-Related Stress
The current COVID19 pandemic has afflicted almost the whole globe. The stress related to the pandemic, not the direct virus-related injury, can be potentially associated with acute cardiovascular events due to a large list of…
- Conditions
- Acute Myocardial Infarction, Ventricular Tachycardia, Sudden Cardiac Death, Stroke, Acute
- Trial name
- JoCORE (NCT04368637)
- Where
- 5 sites in Jordan
- Volunteers
- 50 people
- Sponsor
- Jordan Collaborating Cardiology Group
Myocardial Ischemia, Acute Coronary Syndrome
Cardiac Rehabilitation for Heart Event Recovery (HER)
The purpose of this study is to compare women's cardiac rehabilitation program adherence across three program models.
- Conditions
- Myocardial Ischemia, Acute Coronary Syndrome, Heart Disease, Coronary Artery Disease
- Trial name
- CR4HER (NCT01019135)
- Testing
- Cardiac Rehabilitation
- Where
- 5 sites in Canada
- Volunteers
- 169 people
- Sponsor
- University Health Network, Toronto
Acute Coronary Syndrome, Myocardial Infarction
Evaluation of Lifestyle Education and Events Via Network Text Messages After Acute Coronary Syndrome
To evaluate the usefulness of telephone text messages (TTM) in the control of risk factors and in the reduction of events in the first year after an ACS (acute coronary syndrome).
- Conditions
- Acute Coronary Syndrome, Myocardial Infarction, Cardiovascular Diseases
- Trial name
- Elena (NCT07331415)
- Testing
- Text messaging and Usual Care, Usual Care
- Where
- Spain
- Volunteers
- 370 people
- Sponsor
- Fundación EPIC
Acute Kidney Injury, Heart Failure
Remote Ischemic Preconditioning for Renal and Cardiac Protection in Congestive Heart Failure (RICH) Trial
This is a prospective, double-blind, sham-controlled, multicenter, randomized clinical trial is to study the effects of remote ischemic preconditioning on contrast-associated acute kidney injury, functional capacity, and major…
- Conditions
- Acute Kidney Injury, Heart Failure, Contrast Induced Nephropathy, Coronary Angiography
- Trial name
- RICH (NCT04982419)
- Testing
- Remote ischemic preconditioning
- Where
- 3 sites in United States
- Volunteers
- 240 people
- Sponsor
- VA Office of Research and Development
Acute Coronary Disease, Angina Unstable
Clopidogrel Optimal Loading Dose Usage to Reduce Recurrent EveNTs/Optimal Antiplatelet Strategy for InterventionS
The purpose of this study is to evaluate whether a higher dosage of clopidogrel with aspirin (two doses) will decrease the risk of ischemic complications (cardiac death (CV death), myocardial infarction (MI), stroke) after a…
- Trial name
- CURRENT/OASIS7 (NCT00335452)
- Testing
- Clopidogrel, acetylsalicyclic acid (ASA)
- Where
- 38 sites in United States, Argentina and 36 more
- Volunteers
- 25,086 people
- Sponsor
- Sanofi
Aortic Dissection Type A, Acute Kidney Injury Cardiac Surgery
Preoperative Ankle-Brachial Index and Renal Adverse Events After Acute Type A Aortic Dissection Surgery
This single-centre retrospective observational cohort study evaluated the association between preoperative cuff-derived ankle-brachial index (ABI) and postoperative acute kidney injury (AKI) in adults undergoing emergency repair…
- Trial name
- NCT07668830
- Testing
- Preoperative Ankle-Brachial Index
- Where
- China
- Volunteers
- 516 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
AKI - Acute Kidney Injury, CABG
Perfusion Related Evaluation of Systemic and Renal Vulnerability to Events in CABG
The goal of this observational study is to learn whether high abdominal pressure or low blood flow pressure to the kidneys is linked to kidney injury after heart surgery.
- Trial name
- PRESERVE-CABG (NCT07085286)
- Testing
- Continous IAP measurement
- Volunteers
- 45 people
- Sponsor
- Medical University of Lublin
PreDiabetes, Acute Myocardial Infarction
Metformin and Prevention of Cardiovascular Events in Patients With Acute Myocardial Infarction and Prediabetes (MIMET)
Prediabetes is associated to an increased risk of cardiovascular disease and mortality. Although metformin can delay progression to diabetes there is a lack of RCTs evaluating the effect of metformin on cardiovascular outcomes.
- Conditions
- PreDiabetes, Acute Myocardial Infarction, Non ST Elevation Myocardial Infarction, ST Elevation Myocardial Infarction
- Trial name
- MIMET (NCT05182970)
- Testing
- Metformin
- Where
- Sweden
- Volunteers
- 5,160 people
- Sponsor
- Karolinska Institutet
Acute Coronary Syndrome, Drug-eluting Stent
The Impact of Early Surgery and Maintenance of Antiplatelet Therapy on Intraoperative Bleeding and Major Adverse Cardiovascular Event After Percutaneous Coronary Intervention
Recent guidelines of the ACC/AHA suggest that elective non-cardiac surgery (NCS) should optimally be delayed one year after percutaneous coronary intervention (PCI) with drug-eluting stent (DES).
- Conditions
- Acute Coronary Syndrome, Drug-eluting Stent, Aspirin
- Trial name
- NCT02941588
- Testing
- Non-cardiac surgery
- Where
- South Korea
- Volunteers
- 1,582 people
- Sponsor
- Seoul National University Hospital
Acute Coronary Syndrome or B Cerebral Infarction Requiring DAPT(Clopidogrel + Aspirin) for at Least 6 Months
An Observational Study to Evaluate the Incidence of MACCE According to Time Interval of Taking Medication in Patients With Acute Coronary Syndrome or Cerebral Infarction Who Received DAPT for the Secondary Prevention and Esomezol Cap for the Prevention of Gastrointestinal Bleeding
This study is to evaluate the incidence rate of Major Adverse CardioCerebrovascular Events(MACCE) in Patients with Acute Coronary Syndrome or Cerebral Infarction Who Received DAPT for the secondary prevention and Esomezol Cap for…
- Trial name
- NCT05487560
- Testing
- Esomezol Cap
- Where
- South Korea
- Volunteers
- 4,133 people
- Sponsor
- Hanmi Pharmaceutical Company Limited
Intradialytic Hypotension, Cardiac Event
BIA Versus Physician Adjustment in Acute Kidney Injury Patients Requiring Renal Replacement Therapy
This study was designed to compare the efficacy of BIA and physician adjustment to prevent intradialytic hypotension in patients with acute kidney injury who received renal replacement therapy.
- Conditions
- Intradialytic Hypotension, Cardiac Event, Renal Insufficiency, Hospital Length of Stay
- Trial name
- NCT03916861
- Testing
- Bioelectrical Impedance Analysis, Physician-guided
- Where
- Thailand
- Volunteers
- 9 people
- Sponsor
- Bangkok Metropolitan Administration Medical College and Vajira Hospital
Acute Coronary Syndrome
Prevention of Cardiovascular Events by Antiplatelet Agents After Acute Coronary Syndrome
Prevention of cardiovascular events by antiplatelet agents after acute coronary syndrome
- Trial name
- AReMIS (NCT01952392)
- Where
- France
- Volunteers
- 4,992 people
- Sponsor
- AstraZeneca
Cardio-Renal Syndrome, Coronary Angiography
Risk Factors and Prognosis of Adverse Cardiovascular and Kidney Events After Coronary Intervention
As a single center, retrospective observation study in Guangdong Institute of Cardiovascular Diseases, this study included the main study population of patients who underwent coronary angiography and / or coronary intervention…
- Conditions
- Cardio-Renal Syndrome, Coronary Angiography, Coronary Artery Disease, Kidney Diseases
- Trial name
- NCT04407936
- Where
- China
- Volunteers
- 88,938 people
- Sponsor
- Guangdong Provincial People's Hospital
Acute Coronary Syndrome
High Sensitive C-reactive Protein to Albumin Ratio in Acute Coronary Syndrome
assess the use of hs- C-reactive protein to albumin ratio (hs-CAR) in prediction of in-hospital short-term major adverse cardiac events (MACEs) in acute coronary syndrome (ACS) patients
- Trial name
- NCT06673381
- Where
- Egypt
- Volunteers
- 240 people
- Sponsor
- Sohag University
Acute Coronary Syndromes, Secondary Prevention
triPle Oral thERapy With Bempedoic Acid vs uSual Care in Early Lipid Management of Patients With acUte coronAry synDromE
Early and intensive LDL-cholesterol (LDL-c) reduction is associated with improved short-term and long-term outcomes. Bempedoic acid is an oral ATP citrate lyase inhibitor that lowers LDL-c upstream of HMG-CoA reductase.
- Conditions
- Acute Coronary Syndromes, Secondary Prevention, Lipids
- Trial name
- PERSUADE (NCT07440381)
- Testing
- Triple oral lipid lowering treatment
- Where
- 35 sites in Italy
- Volunteers
- 600 people
- Sponsor
- Heart Care Foundation
Acute Coronary Syndrome, Myocardial Infarction
An Efficacy and Safety Study for Rivaroxaban in Patients With Acute Coronary Syndrome
The purpose of this study is to determine whether rivaroxaban in addition to standard care reduces the risk of the composite of cardiovascular death, myocardial infarction, or stroke in patients with a recent acute coronary…
- Conditions
- Acute Coronary Syndrome, Myocardial Infarction, Myocardial Ischemia, Unstable Angina
- Trial name
- NCT00809965
- Testing
- Rivaroxaban 2.5 mg, Rivaroxaban 5 mg, Standard of care
- Where
- 556 sites in United States, Argentina and 41 more
- Volunteers
- 15,526 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Non-ST Elevation Myocardial Infarction (NSTEMI), Acute Coronary Syndrome
Left Atrial Strain for Predicting MACE in NSTEMI
This prospective observational study aims to evaluate whether left atrial reservoir strain, measured by two-dimensional speckle tracking echocardiography, independently predicts 6-month major adverse cardiovascular events (MACE)…
- Conditions
- Non-ST Elevation Myocardial Infarction (NSTEMI), Acute Coronary Syndrome, Myocardial Infarction
- Trial name
- NCT07797634
- Volunteers
- 150 people
- Sponsor
- Assiut University
Perioperative Complications, Perioperative/Postoperative Complications
Perioperative Database of Chinese Elderly Patients
The investigators aim to establish a prospective database of perioperative elderly patients from multiple regions and centers. Collected data involves postoperative complications of the central nervous system, cardiovascular…
- Conditions
- Perioperative Complications, Perioperative/Postoperative Complications, Perioperative Adverse Events
- Trial name
- PDCEP (NCT04911530)
- Testing
- no intervention
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Chinese PLA General Hospital
Acute Coronary Syndrome
The Stabilization Of pLaques usIng Darapladib-Thrombolysis In Myocardial Infarction 52 Trial
This study will test whether darapladib can safely lower the chances of having a cardiovascular event (such as a heart attack or urgent coronary revascularization (e.g.
- Trial name
- SOLID-TIMI 52 (NCT01000727)
- Testing
- Darapladib 160 mg, Standard Therapy
- Where
- 914 sites in United States, Argentina and 34 more
- Volunteers
- 13,026 people
- Sponsor
- GlaxoSmithKline
Acute Coronary Syndrome, Percutaneous Coronary Intervention
Effectiveness of Artificial Intelligent Based mHealth System to Reduce ACS Patients Bleeding Events After PCI
The present study was designed to observe the effectiveness of artificial intelligent based mHealth system(Chronic disease management system) to reduce bleeding events in ACS patients undergoing PCI.
- Conditions
- Acute Coronary Syndrome, Percutaneous Coronary Intervention, Bleeding
- Trial name
- NCT03738930
- Testing
- AI based mHealth system
- Where
- China
- Volunteers
- 420 people
- Sponsor
- Chinese PLA General Hospital