Clinical trials: Acute Dyspnea
Dyspnea
Artificial Intelligence to Improve Physicians' Interpretation of Chest X-Rays in Breathless Patients
Identifying the cause of breathlessness in acute patients in the emergency department is critical and challenging. The chest X-ray is central but challenging to read for non-radiologist physicians.
- Trial name
- XRAI (NCT05117320)
- Testing
- AI support
- Where
- Denmark
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Bispebjerg Hospital
Dyspnea
Diagnostic Performance of Chest Computed Tomography Scan in Patients Aged 65 and Over Presenting to Emergency Room With Acute Dyspnea
In acute dyspnea, the use of chest radiography is frequent and not very contributive, especially in the elderly patients. However, early diagnosis of the cause of dyspnea in the ED is associated with a better prognosis, in…
- Trial name
- CT-Dys (NCT06104475)
- Testing
- CT scan
- Where
- France
- Volunteers
- 240 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Dyspnea, Acute Decompensated Heart Failure
Evaluation of Cardiopulmonary Diseases by Ultrasound
Historically, ultrasound imaging of the lung parenchyma has been challenging because of the high total ultrasound energy attenuation and scattering by the air in the lungs.
- Trial name
- NCT02248831
- Testing
- Recording Doppler ultrasound signals noninvasively
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- Echosense Ltd.
Shortness of Breath, Acute Respiratory Failure
Enhanced FoCUS in Patients With Shortness of Breath
Retrospective observational study performed in a internal medicine ward of a French university hospital. Included patients were hospitalized for acute shortness of breath who have benefited from a eFOCUS which was defined as a…
- Trial name
- eFOCUS (NCT05403619)
- Testing
- Diagnostic test
- Where
- France
- Volunteers
- 119 people
- Sponsor
- Nantes University Hospital
Acute Decompensated Heart Failure
Gas Exchange for Predicting Hospital Heart Failure Readmissions
To determine whether, and if so, which gas exchange parameters measured on the Shape-HF Cardiopulmonary Exercise Testing System predict 30 and 180 day re-hospitalization in subjects discharged from hospitalization for an episode…
- Trial name
- NCT01960218
- Where
- 7 sites in United States
- Volunteers
- 120 people
- Sponsor
- Shape Medical Systems, Inc.
Heart Failure, Congestive, Dyspnea
Double Blind Randomized Placebo Controlled Trial of Natrecor in Acute Decompensated Heart Failure With Normal EF
Heart failure (HF) is a disease that is caused by a reduced heart muscle function. Reduced heart muscle function can occur as a consequence of reduced pumping activity from a weak heart muscle or because of a stiff heart muscle.
- Conditions
- Heart Failure, Congestive, Dyspnea, Pulmonary Edema
- Trial name
- NCT00505791
- Testing
- Nesiritide
- Where
- United States
- Sponsor
- University of Medicine and Dentistry of New Jersey
Dyspnea, Chronic Renal Failure
POCUS VS CT in Diagnosis of Acute Dyspnea in Chronic Hemodialysis Patients
Estimate the predictive value of POCUS in diagnosis of different causes of acute dyspnea in hemodialysis patients and compare between POCUS and CT in differentiation the causes of acute dyspnea in those population.
- Trial name
- NCT05729035
- Testing
- POCUS
- Volunteers
- 100 people
- Sponsor
- Randa Ahmed Sarhan
Post-COVID-19 Syndrome, COVID-19
Evaluation of Treatment With Viusid in Post-COVID-19 Syndrome
Reports of long-lasting symptoms of COVID-19 are increasing, but little is known about the prevalence of risk factors or whether it is possible to predict a prolonged course at disease onset.
- Conditions
- Post-COVID-19 Syndrome, COVID-19, Dyspnea, Fatigue
- Trial name
- NCT06437210
- Testing
- Viusid Oral Solution
- Where
- Colombia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Catalysis SL
Acute Lung Injury, Acute Respiratory Distress Syndrome
Timing and Intensity of the Exposures and Attributable Burden of Acute Lung Injury
The purpose of the study is to identify the patients at high risk of developing Acute Lung Injury (ALI) at the time of hospital admission, and before intensive care unit admission.
- Trial name
- LIPS (NCT00980915)
- Where
- United States
- Volunteers
- 6,600 people
- Sponsor
- Mayo Clinic
Chest Pain, Shortness of Breath
ProspEctive First Evaluation in Chest Pain Trial
The purpose of this study is to determine the best initial test in patients admitted to the hospital complaining of chest pain.
- Conditions
- Chest Pain, Shortness of Breath, Suspected Acute Coronary Syndrome
- Trial name
- PERFECT (NCT01604655)
- Testing
- Coronary CT Angiography, Stress Test
- Where
- United States
- Volunteers
- 411 people
- Sponsor
- St. Luke's-Roosevelt Hospital Center
Respiratory Insufficiency
High Flow Nasal Oxygen at Extubation for Adults Requiring a Breathing Tube for Treating Severe Breathing Difficulties
The goal of this feasibility study is to learn whether a new approach to breathing tube removal within the Intensive Care Unit is safe and acceptable to participants who require a breathing tube for the management of severe…
- Trial name
- Pre-SAFEx (NCT05904652)
- Testing
- Fisher and Paykel "HealthCare Airvo™ 3" high flow system, Conventional Oxygen Therapy
- Where
- United Kingdom
- Volunteers
- 2 people
- Sponsor
- NHS Greater Glasgow and Clyde
COVID-19
Pulmonary Rehabilitation in Post-Acute Period of COVID-19 Infection
The aim of this study is to investigate the efficacy of pulmonary rehabilitation(PR) applied in the isolation processes of post-acute patients with mild and moderate symptoms who had positive COVID-19 test on dyspnea,muscle…
- Trial name
- NCT04365738
- Testing
- Rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 270 people
- Sponsor
- Istanbul Bilgi University
Long Covid19
Diaphragm Dysfunction After COVID-19 as Determined by Dynamic Chest Radiography
Dynamic chest radiography (DCR) is a rapid and easily performed technique that captures real-time continuous images of the moving chest.
- Trial name
- DD-COVID-19 (NCT06175455)
- Testing
- dynamic chest radiography
- Where
- China
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Nanfang Hospital, Southern Medical University
Dyspnea and Respiratory Insufficiency in Children
Multidimensional Characterization of Dyspnea in Children
There is no specific tool existing to describe dyspnea in children in a multidimensional way. It has been shown in adult studies that multidimensional dyspnea evaluation scales are well correlated to quality of life and…
- Trial name
- DYSPED (NCT05500833)
- Testing
- Multidimentional observation scale (MDP)
- Where
- France
- Volunteers
- 400 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Asthma Exacerbation
Treatment of Acute Asthma in ER With Combination of Systemic Steroids and Inhaled Steroids
We assume that the combination of systemic steroids and inhaled steroid in the first hour of treatment in the ER will decrease the admission rate and improve faster the pulmonary function.
- Trial name
- NCT00397267
- Testing
- inhalation of corticosteroids
- Where
- Israel
- Volunteers
- 120 people
- Sponsor
- Soroka University Medical Center
Shortness of Breath, Acute Exacerbation
NT-proBNP for Evaluation of the Dyspneic Patient in the Emergency Room and the Medical Ward
The proposed study intends to evaluate the impact of the NT-proBNP assay on the diagnosis of heart failure in patients with dyspnea of unknown etiology presenting to the emergency room and admitted to the medical wards.
- Trial name
- NCT00271128
- Where
- Israel
- Volunteers
- 500 people
- Sponsor
- Hillel Yaffe Medical Center
Acute Myocardial Infarction, Heart Failure
SHORTness of Breath In the Emergency Department (SHORTIE)
SHORTIE is a two-phase study to determine the impact of the Triage Profiler S.O.B. (Shortness Of Breath) Panel on patient management, outcome, and cost.
- Conditions
- Acute Myocardial Infarction, Heart Failure, Pulmonary Embolism
- Trial name
- NCT00206830
- Testing
- Triage Profiler S.O.B. Panel
- Where
- 5 sites in United States
- Volunteers
- 306 people
- Sponsor
- Abbott RDx Cardiometabolic
Pulmonary Complication, Dyspnea
Incentive Spirometry in Non-critically Ill Hospitalized Patients With Acute Respiratory Failure
To evaluate the use of Incentive Spirometry in Non-critically Ill Hospitalized Patients With Shortness of Breath.
- Conditions
- Pulmonary Complication, Dyspnea, Pneumonia, COPD
- Trial name
- NCT02873000
- Testing
- Incentive Spirometry
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Jewish Hospital, Cincinnati, Ohio
Dyspnea, Peripheral Edema
NT-proBNP and New Biomarkers in Patients With Dyspnea and/or Peripheral Edema
The objectives of this study are to: Evaluate the sensitivity and specificity of NT-proBNP (N-terminal prohormone brain natriuretic peptide) and new biomarker measurements for the diagnosis of heart failure in patients with acute…
- Trial name
- MANPRO (NCT00143793)
- Where
- Germany
- Volunteers
- 400 people
- Sponsor
- Universitätsmedizin Mannheim
Acute Dyspnea
Pathway and Urgent caRe of Dyspneic Patient at the Emergency Department in LorrainE District (PURPLE)
This is an observational prospective multicenter study of patients admitted for acute dyspnea in an emergency department of the participating centers in the Lorraine district.
- Trial name
- PURPLE (NCT03194243)
- Where
- 9 sites in France
- Volunteers
- 75,000 people
- Sponsor
- Central Hospital, Nancy, France