Clinical trials: Acute Exacerbation of Chronic Obstructive Pulmonary Disease
COPD Acute Exacerbation
Rademikibart Add-on Treatment of an Acute COPD Exacerbation (Seabreeze STAT COPD)
This is a Phase 2, multicenter study in adult participants with an acute COPD exacerbation and type 2 inflammation
- Trial name
- NCT06940154
- Testing
- Rademikibart in prefilled syringe
- Where
- 52 sites in United States, Argentina and 4 more
- Volunteers
- 159 people
- Sponsor
- Connect Biopharm LLC
COPD
A Study Comparing Doxycycline and Levofloxacin for Treating COPD Exacerbations
This study will include patients with chronic obstructive pulmonary disease (COPD) who present with an acute exacerbation. Participants will be randomly assigned to receive either doxycycline or levofloxacin for 5 days.
- Trial name
- DOLE-COPD (NCT06915688)
- Testing
- Doxycycline, Levofloxacin
- Where
- Pakistan
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- Amina Aslam
Pneumococcal Infections, COPD
Immunization To Prevent Acute COPD Exacerbations
Prospective multicenter observational study, to evaluate the impact of routine clinical practice vaccination with PCV13 on the reduction of the risk of moderate/severe COPD exacerbations
- Trial name
- NCT03276754
- Where
- 11 sites in Spain
- Volunteers
- 530 people
- Sponsor
- Pfizer
Asthma, COPD
Acute Exacerbations Treated With BenRAlizumab (The ABRA Study)
Exacerbations of asthma and COPD are an important cause of hospital admission and the main cause of annual winter bed shortages.
- Trial name
- ABRA (NCT04098718)
- Testing
- Benralizumab, Prednisolone
- Where
- United Kingdom
- Volunteers
- 158 people
- Sponsor
- University of Oxford
Chronic Obstructive Pulmonary Disease
Safety & Efficacy of BCT197A2201 in COPD Patients Presenting With an Exacerbation
This study will assess preliminary parameters of safety and efficacy of a single dose of BCT197 in patients with a Chronic Obstructive Pulmonary Disease (COPD) exacerbation.
- Trial name
- NCT01332097
- Testing
- BCT197, Prednisone
- Where
- 6 sites in Bulgaria, Romania and 1 more
- Volunteers
- 183 people
- Sponsor
- Mereo BioPharma
COPD (Chronic Obstructive Pulmonary Disease), Acute Exacerbation of COPD
Survey on NIV Settings in the Intensive Care Unit for Acute Exacerbation of COPD
Introduction Chronic obstructive pulmonary disease (COPD) is a common condition and the fourth leading cause of death worldwide.
- Conditions
- COPD (Chronic Obstructive Pulmonary Disease), Acute Exacerbation of COPD, Hypercapnic Respiratory Failure, COPD
- Trial name
- NIV-ICU (NCT06888180)
- Testing
- Non interventional study
- Volunteers
- 976 people
- Sponsor
- University Hospital, Caen