Clinical trials: Acute Illness
Altitude Hypoxia
The Physiological Effects of Acute and Ramp Simulated Altitude Exposure During Simulated Flight Tasks
The purpose of this study is to investigate which physiological process that controls normal human body homeostasis is affected by low levels of acute hypoxic exposure and whether there is a difference in those physiological…
- Trial name
- NCT05867719
- Testing
- Hypoxic breathing conditions
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Texas, El Paso
Acute Pancreatitis
An Observational Study of the Role of Intra-abdominal Pressure Monitoring in Patients With Acute Pancreatitis
Acute pancreatitis is a multi-system disease with an unpredictable clinical course and significant morbidity and mortality Approximately 20% of patients develop multi-organ failure requiring management within a critical care…
- Trial name
- NCT01611532
- Where
- United Kingdom
- Volunteers
- 218 people
- Sponsor
- Emma Aitken
Critical Illness
Effectiveness and Safety of an Early Mobilization Protocol in a Pediatric Intensive Care Unit
This study evaluates the safety and effectiveness of an early rehabilitation program in a pediatric intensive care unit (PICU). Half of the participants will receive intensive and frequent an early mobilization program and others…
- Trial name
- NCT04524065
- Testing
- Early rehabilitation protocol for children hospitalized in the PICU
- Where
- South Korea
- Volunteers
- 142 people
- Sponsor
- Samsung Medical Center
Inflammation, Acute Illness
Nicotinamide Riboside in Hospitalized Patients
Patients will receive oral nicotinamide riboside or placebo and clinical and paraclinical outcome will be determined
- Trial name
- NCT04110028
- Testing
- Nicotinamide riboside
- Where
- Norway
- Volunteers
- 57 people
- Sponsor
- Oslo University Hospital
Critical Illness, Brain Injuries
Therapeutic Drug Monitoring of Beta-lactams and Renal Hyperclearance in Patients Admitted to Intensive Care for Acute Brain Injury
Augmented Renal Clearance (ARC), defined as a supraphysiological increase in renal function, is frequently observed in critically ill patients, particularly those with acute brain injury.
- Trial name
- BETALACT-ARC (NCT06999161)
- Where
- France
- Volunteers
- 140 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Hypobaric Hypoxia, Metabolomics
Oxidative Stress in Hypobaric Hypoxia
The trial investigates changes in metabolism during high altitude expedition up to 6865m. A mass-spectrometry based platform is used to detect different oxidative stress related metabolites.
- Conditions
- Hypobaric Hypoxia, Metabolomics, Oxidative Stress, Acute Mountain Sickness
- Trial name
- NCT01436383
- Testing
- Hypoxic exposure
- Where
- Switzerland
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern