Clinical trials: Acute Ischemic Stroke Patients
Ischemic Stroke, Stroke
A Functional MRI Study: Assessing Brain Function in Post Stoke Patients
This is a prospective, single center, observational clinical study containing two cohorts the healthy cohort and post stroke cohort. A total of 13 subjects will be enrolled.
- Conditions
- Ischemic Stroke, Stroke, Acute Ischemic Stroke
- Trial name
- NCT06573840
- Testing
- NeuroGlove
- Volunteers
- healthy volunteers welcome
- Sponsor
- NeuroGlove LLC
Collateral Circulation, Any Site
Intracranial Collaterals in Acute Stroke and Clinical Outcome
Assessment of the evolution of intracranial collaterals and its relationship with functional outcomes in acute ischemic stroke (AIS) patients treated with IV tissue plasminogen activator (tPA).
- Trial name
- NCT03311386
- Testing
- Actilyse
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Assiut University
Cerebral Stroke, Cerebrovascular Accident
Trial and Cost Effectiveness Evaluation of Intra-arterial Thrombectomy in Acute Ischemic Stroke
THRACE is a controled, multicenter and randomized trial. The primary objective of this study is to determine whether a combined approach intravenous thrombolysis (IV) + Mechanical thrombectomy is superior to the reference…
- Trial name
- THRACE (NCT01062698)
- Testing
- Alteplase (rt-PA)/Actilyse, Mechanic thrombectomy (MERCI, PENUMBRA, CATCH, SOLITAIRE)
- Where
- France
- Volunteers
- 412 people
- Sponsor
- Central Hospital, Nancy, France
Acute Ischemic Stroke
Safety Study of Carbamylated Erythropoietin (CEPO) to Treat Patients With Acute Ischemic Stroke
The primary purpose of the study is to determine whether carbamylated erythropoietin (CEPO) is a safe treatment for patients who have suffered an acute ischemic stroke.
- Trial name
- NCT00756249
- Testing
- Lu AA24493 (CEPO)
- Where
- 5 sites in Finland, France and 3 more
- Volunteers
- 16 people
- Sponsor
- H. Lundbeck A/S
Acute Ischemic Stroke
Safety and Preliminary Efficacy of Allogeneic Endothelial Progenitor Cells (EPCs) in Patients With Acute Ischemic Stroke
This is a multicenter, randomized, double-blind, placebo-controlled, dose-Escalation clinical study to investigate the safety and efficacy of EPCs transplantation in Acute ischemic stroke.
- Trial name
- NCT05993884
- Testing
- iEPCs
- Where
- 2 sites in China
- Volunteers
- 27 people
- Sponsor
- Allife Medical Science and Technology Co., Ltd.
Ischemic Stroke, Acute
Innovative Technologies in Restoring Gait and Balance Funtions in Ischemic Stroke Patients at the Inpatient Stage
The scientific hypothesis was based on data on the effectiveness of the usage of robotic mechanotherapy and virtual reality technologies.
- Trial name
- NCT05423626
- Testing
- technologies of robotic mechanotherapy with FES, biofeedback virtual reality technologies
- Where
- Russia
- Volunteers
- 120 people
- Sponsor
- Moscow Scientific and Practical Center of Medical Rehabilitation, Restorative and Sports Medicine
Ischemic Stroke
Improving the Quality of Life of Stroke Patients Using the Armeo Spring Device
The main goal will be to evaluate the effect of improving the quality of movement of the upper limb (using an evaluation exercise in the software of the Armeo Spring device) on the development of the quality of life after stroke…
- Trial name
- NCT05743413
- Testing
- Armeo Spring physiotherapy, Standard physiotherapy
- Where
- Czechia
- Volunteers
- 10 people
- Sponsor
- University Hospital Ostrava
Acute Ischemic Stroke, Mechanical Thrombectomy
Rapid Local Ischemic Postconditioning in Acute Ischemic Stroke
The objective of this clinical trial is to determine whether rapid local ischemic postconditioning (RL-IPostC) is effective in preventing brain edema and safe in acute ischemic stroke (AIS) patients treated with mechanical…
- Conditions
- Acute Ischemic Stroke, Mechanical Thrombectomy, Ischemic Postconditioning, Brain Edema
- Trial name
- RAPID-SAVE (NCT06307743)
- Testing
- rapid local ischemic postconditioning
- Volunteers
- 135 people
- Sponsor
- Shanghai Jiao Tong University Affiliated Sixth People's Hospital
Acute Ischemic Stroke
Platelet Function in Patients With Ischemic Stroke Treated With Anti-thrombotic or Thrombolytic
Acute stroke afflicts nearly 700,000 patients in the US and is the number 3 cause of death. Only 2-9% of this large number is treated with t-PA if they arrive within 4.5 hours.
- Trial name
- NCT05415150
- Testing
- Thrombolytic Agent
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Baylor College of Medicine
Acute Ischemic Stroke
Prospective Registry for Assessment of Acute Ischemic Stroke Patients Treated With Neurothrombectomy Devices in India
PRAAN is a post-market registry designed to collect real-world data associated with the use of Medtronic market release neurothrombectomy devices in acute ischemic stroke (AIS) patients from India.
- Trial name
- PRAAN (NCT05005962)
- Testing
- Neurothrombectomy
- Where
- 14 sites in India
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Medtronic Neurovascular Clinical Affairs
Stroke, Cerebrovascular Stroke
Addressing Real-world Anticoagulant Management Issues in Stroke
The Addressing Real-world Anticoagulant Management Issues in Stroke (ARAMIS) registry is designed to provide important and timely insight into the management of acute stroke patients who are on novel oral anticoagulants in…
- Conditions
- Stroke, Cerebrovascular Stroke, Intracerebral Hemorrhage
- Trial name
- ARAMIS (NCT02478177)
- Where
- United States
- Volunteers
- 6,000 people
- Sponsor
- Duke University
Stroke, Acute, Ischemic Stroke
Rheo-Erythrocrine Dysfunction as a Biomarker for RIC Treatment in Acute Ischemic Stroke
This study aims to investigate whether Remote Ischemic Conditioning (RIC) improves rheo-erythrocrine dysfunction in acute ischemic stroke
- Conditions
- Stroke, Acute, Ischemic Stroke, Cerebrovascular Disorders, Central Nervous System Diseases
- Trial name
- ENOS (NCT04266639)
- Testing
- Remote Ischemic Conditioning
- Where
- Denmark
- Volunteers
- 45 people
- Sponsor
- Grethe Andersen
Large Vessel Occlusion, Stroke Acute
Rescue Stenting and Intravenous Thrombolysis In Patients With Large Vessel Ischemic Stroke
Intravenous thrombolysis (IVT) and mechanical thrombectomy (MT) are the standard of care for treating selected patients with acute large-vessel occlusion stroke (LVOS).
- Conditions
- Large Vessel Occlusion, Stroke Acute, Thrombolysis, Rescue Stenting
- Trial name
- STARS (NCT06727006)
- Where
- 7 sites in Italy
- Volunteers
- 400 people
- Sponsor
- ASST Santi Paolo e Carlo
Acute Ischemic Stroke
Human Placenta-derived 3D Mesenchymal Stem Cells(Guojianqingke)
This is a Phase I/IIa clinical trial evaluating human placental-derived 3D mesenchymal stem cell (MSC) injection in patients with acute ischemic stroke (AIS).
- Trial name
- 3D MSC - QK01 (NCT07635758)
- Testing
- Human Placenta-derived 3D Mesenchymal Stem Cells (Guojiangqingke)
- Where
- China
- Volunteers
- 24 people
- Sponsor
- Chinese PLA General Hospital
Stroke Acute
EnDOvascular Therapy for Late WiNdow IschEmic Stroke Patients Selected bY AutoMatic Plain ComputErized Tomography
The DONE SYMPLE Investigator-initiated phase III prospective, randomized, open-label, blinded endpoint-controlled clinical trial.
- Trial name
- DONE SYMPLE (NCT07001852)
- Testing
- Endovascular Therapy (Mechanical Thrombectomy), Standard Medical Management
- Where
- 2 sites in United States, Armenia
- Volunteers
- 500 people
- Sponsor
- Santiago Ortega Gutierrez
Cardiac Death, Hemorrhage
Efficacy and Safety of BiomatrixTM Stent and 5mg-Maintenance Dose of Prasugrel in Patients With Acute Coronary Syndrome
The purpose of this study is to evaluate the efficacy and safety of 5mg maintenance dose (MD) of prasugrel in patients with acute myocardial infarction (AMI) who underwent percutaneous coronary intervention (PCI) with BiomatrixTM…
- Conditions
- Cardiac Death, Hemorrhage, Cerebrovascular Accident, Myocardial Infarction
- Trial name
- BEAUTY-II (NCT02446730)
- Testing
- BES (biodegradable polymer biolimus-eluting stent), Prasugel, Clopidogrel
- Where
- South Korea
- Volunteers
- 1,400 people, healthy volunteers welcome
- Sponsor
- Chonnam National University Hospital
Acute Ischemic Stroke
A Study of r-PA Treating Patients With Acute Ischemic Stroke（RAISE）
The purpose of this study is to assess the efficacy and safety of recombinant human tissue plasminogen kinase derivatives for injection and alteplase in the treatment of patients with acute ischemic stroke within 4.5 hours.
- Trial name
- NCT05295173
- Testing
- Injection of recombinant human tissue plasminogen kinase derivatives, Recombinant human tissue plasminogen activator
- Where
- 78 sites in China
- Volunteers
- 1,412 people
- Sponsor
- Angde Biotech Pharmaceutical Co., Ltd.
Acute Ischemic Stroke Patients
Hyperglycemia as a Prognostic Factor In Acute Ischemic Stroke Patients
Background: Hyperglycemia is encountered in 20% to 40% of acute stroke patients, with or without a pre-morbid diagnosis of diabetes mellitus.
- Trial name
- NCT04196322
- Testing
- observational study
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Ain Shams University
Acute Stroke
BraiN20® Medical Device in Suspected Acute Stroke Patients
Time is Brain company (http://www.tibtimeisbrain.com/about_us/) developed BraiN20®, a medical device to assess the presence and characteristics of the N20 signal of SEP.
- Trial name
- PROMISE-GLOB (NCT06421337)
- Testing
- BraiN20(R)
- Where
- 3 sites in Spain
- Volunteers
- 500 people
- Sponsor
- Alicia Martínez Piñeiro
Acute Ischemic Stroke
Aureva Transcranial Ultrasound Device With tPA in Patients With Acute Ischemic Stroke
This is a randomized, placebo controlled, double-blind phase 3 clinical study to evaluate the efficacy and safety of transcranial ultrasound (TUS) using the Sonolysis Headframe as an adjunctive therapy to intravenous (IV) tissue…
- Trial name
- TRUST (NCT03519737)
- Testing
- tPA in combination with the Sonolysis Headframe (TUS)
- Where
- 2 sites in United States
- Volunteers
- 596 people
- Sponsor
- Cerevast Medical, Inc.