Clinical trials: Acute Ischemic Stroke Patients
Brain Ischemia
Informative of Surface Electromyography and Prognostic Factors in Assessing the Recovery of Balance and Gait After Stroke
The aim of the biomedical research is to determine the informativeness and prognostic factors of surface electromyography by assessing the probability of recovery of balance and gait parameters in the second stage of…
- Trial name
- NCT04981184
- Testing
- Gait and balance measurement
- Where
- Lithuania
- Volunteers
- 100 people
- Sponsor
- Lithuanian University of Health Sciences
Acute Stroke
Hemodynamic Changes in Acute Ischaemic Stroke Patients
1. To assess Hemodynamic changes in rtPA receiving Acute Ischaemic Stroke patients. 2. To assess the efficacy of rtPA in treatment of Acute Ischaemic Stroke patients. 3.
- Trial name
- NCT05195983
- Volunteers
- 50 people
- Sponsor
- Assiut University
Acute Ischemic Stroke
Dynamic Changes of the Human Microbiome Predict the Risk of Poor Prognosis in Patients With Acute Ischemic Stroke: a Multi-center Study
Recent studies have found a close relationship between acute ischemic stroke(AIS) and gut microbiota, but whether the dynamic changes in human microbiome after stroke can predict poor prognosis of stroke remains unclear.
- Trial name
- NCT04978701
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Stroke, Ischemic
Resistive Diaphragmatic Breathing Exercise With Pursed Lips Breathing Exercise in Sub-acute Stroke Patients
To determine whether resistive diaphragmatic breathing exercise with pursed lips breathing exercise improve pulmonary function in sub-acute ischemic stroke, To determine whether resistive diaphragmatic breathing exercise with…
- Trial name
- NCT06326801
- Testing
- Resistive Diaphragmatic breathing exercise, Diaphragmatic breathing exercise, Conventional stroke physiotherapy
- Where
- Pakistan
- Volunteers
- 27 people
- Sponsor
- Riphah International University
Acute Cerebrovascular Accident, Thrombectomy
Investigation of Brain Blood Flow Changes in Acute Ischemic Stroke Patients After Successful Endovascular Thrombectomy
Introduction: Endovascular thrombectomy (EVT) is an effective treatment strategy to mitigate the ischemic tissue damage caused by the acute cerebral large-vessel occlusion.
- Conditions
- Acute Cerebrovascular Accident, Thrombectomy, Cerebral Revascularization, No Reflow Phenomenon
- Trial name
- RESTORE-AIS (NCT07534319)
- Testing
- No planned intervention
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- University of Zurich
Coronary Artery Disease, Chest Syndrome
CT Stress Myocardial Perfusion, Fractional Flow Reserve and Angiography in Patients With Stable Chest Pain Syndromes
The purpose of the DYNAMITE trial (Dynamic CT stress myocardial perfusion, CT fractional flow reserve (FFR-CT) and coronary CT angiography for optimized treatment strategy in patients with chest pain syndromes) is to determine…
- Conditions
- Coronary Artery Disease, Chest Syndrome, Acute Myocardial Infarction, Heart Failure
- Trial name
- DYNAMITE (NCT04709900)
- Testing
- CT angiography, FFR-CT and stress CT myocardial perfusion
- Where
- Denmark
- Volunteers
- 2,000 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Ischemic Stroke, Cortisol; Hypersecretion
Neuroactive Steroids in Acute Ischemic Stroke
Acute ischemic stroke (AIS) represents an economical challenge for health systems all over the globe. Despite increasing knowledge of the pathophysiology of AIS, there is no satisfactory treatment to revert the resulting brain…
- Trial name
- Cortisol (NCT03242304)
- Testing
- Behavioral tests
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hospital Militar Central, Argentina
Ischemic Stroke, Acute, Ischemic Stroke
A Dose-Response Controlled Trial of Bevifibatide for Acute Ischemic Stroke
BCAIS-I is a single-center, randomized, double-blind, dose-response controlled clinical Trial, to preliminarily explore the efficacy of two different maintenance doses of bevifibatide citrate injection in improving 90-day…
- Conditions
- Ischemic Stroke, Acute, Ischemic Stroke, Cerebral Infarction, Brain Diseases
- Trial name
- BCAIS-I (NCT06712004)
- Testing
- Bevifibatide citrate injection
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Zhujiang Hospital
Acute Ischemic Stroke, Abnormal Glucose Metabolism
Effects of Urinary Kallidinogenase in Acute Ischemic Stroke Patients With Abnormal Glucose Metabolism
Urinary kallidinogenase may assist recovery acute ischemic stroke. This study evaluated the impact of urinary kallidinogenase on NIHSS score, modified Rankin scale (mRS) score and fasting glucose levels in patients with AIS…
- Trial name
- NCT04020666
- Testing
- Urinary Kallidinogenase
- Volunteers
- 113 people
- Sponsor
- The Second Hospital of Hebei Medical University
Stroke, Acute Cerebrovascular Accident
Radiofrequency and Cryoablation of the Posterior Wall of the Left Atrium
Atrial fibrillation (AF) is the cause of 20% of strokes, and the risk of stroke in a person suffering from this arrhythmia increases by 5 times.
- Conditions
- Stroke, Acute Cerebrovascular Accident, Transient Ischemic Attack, Death
- Trial name
- NCT06253000
- Testing
- Cryoablation, Radiofrequency ablation
- Where
- Russia
- Volunteers
- 158 people
- Sponsor
- Bakulev Scientific Center of Cardiovascular Surgery
Stroke
Y-6 Sublingual Tablets for Patients With Acute Ischemic Stroke
This study aims to evaluate the efficacy of Y-6 sublingual tablets in improving microcirculation dysfunction and reducing thrombo-inflammation in patients who had AIS caused by LVO and will receive EVT.
- Trial name
- NCT07040085
- Testing
- Y-6
- Volunteers
- 892 people
- Sponsor
- Beijing Tiantan Hospital
Acute Stroke
Impact of Anesthesia Type on Outcome in Patients With Acute Ischemic Stroke (AIS) Undergoing Endovascular Treatment
Recent observational studies have found an association between general anaesthesia and increased post-operative mortality in acute ischemic stroke patients undergoing endovascular treatment.
- Trial name
- CANVAS (NCT02677415)
- Testing
- Intravenous anesthetics, local anesthesia, Controlled ventilation
- Where
- China
- Volunteers
- 640 people
- Sponsor
- Beijing Tiantan Hospital
Ischemic Stroke
Efficacy and Safety of Mexidol® in Stroke Therapy
The main purpose of the clinical trial is to evaluate the efficacy and safety of Mexidol® in sequential treatment for patients in the acute and early recovery periods of ischemic stroke compared to placebo.
- Trial name
- MIR (NCT06437626)
- Testing
- Mexidol (Ethylmethylhydroxypyridine Succinate)
- Where
- 17 sites in Kazakhstan, Russia and 1 more
- Volunteers
- 304 people
- Sponsor
- Pharmasoft
Atrial Fibrillation, Stroke
China Atrial Fibrillation Screening in Acute Ischemic Stroke Patients
Three purpose of this study: 1. Increase diagnosis rate and formulate the flow of diagnosis and treatment of AF in ischemic stroke patients; 2. Evaluation on specificity and sensitivity of STAF score; 3.
- Trial name
- CRIST (NCT02156765)
- Where
- China
- Volunteers
- 3,000 people
- Sponsor
- yongjun wang
Ischemic Stroke, Acute
MEXIDOL® in the Rehabilitation Treatment of Patients With Acute Cerebral Failure
The use of metabolic modulators creates prospects for increasing the efficiency of the rehabilitation treatment of patients with acute cerebral failure
- Trial name
- NCT06221826
- Testing
- Mexidol
- Where
- Russia
- Volunteers
- 60 people
- Sponsor
- Pharmasoft
Cerebrovascular Accident, Brain Ischemia
A Study of Effectiveness and Safety of Abciximab in Patients With Acute Ischemic Stroke (AbESTT-II)
The purpose of this study is to determine the effectiveness of abciximab in the treatment of acute ischemic stroke.
- Conditions
- Cerebrovascular Accident, Brain Ischemia, Acute Disease
- Trial name
- NCT00073372
- Testing
- Abciximab
- Volunteers
- 808 people
- Sponsor
- Centocor, Inc.
Acute Ischemic Stroke, Cerebral Microbleeds
Intracranial Hemorrhage Risk of Intensive Statin in Acute Ischemic Stroke With Cerebral Microbleeds
This study is the first and largest secondary prevention trial about lipid-lowering therapy for acute ischemic stroke patients at high-risk of intracranial hemorrhage.
- Trial name
- NCT05589454
- Testing
- Atorvastatin Calcium tablets 80mg, Atorvastatin Calcium tablets 20mg
- Where
- 5 sites in China
- Volunteers
- 344 people
- Sponsor
- Sichuan Provincial People's Hospital
Acute Ischemic Stroke
Efficacy and Safety of Home-based Structured Physical Exercise in Patients With Acute Ischemic Stroke
This study is a randomized controlled, open-label, blinded endpoint trial. The investigators aim to assess the efficacy and safety of home-based structured physical exercise in participants with acute ischemic stroke.
- Trial name
- HOPE-STROKE 2 (NCT07271082)
- Testing
- Exercise intervention
- Where
- 6 sites in China
- Volunteers
- 208 people
- Sponsor
- Capital Medical University
Stroke Acute
Study of Inflammatory Cells in the Blood and Cerebral Thrombus of Patients Affected by Cerebral Ischemia
This is an observational, prospective and retrospective, single-center study of thrombotic material and blood samples obtained from patients undergoing mechanical endovascular thrombectomy for ischemic stroke caused by large…
- Trial name
- ClotBioInsight (NCT07033988)
- Where
- Italy
- Volunteers
- 380 people
- Sponsor
- IRCCS San Raffaele
Acute Ischemic Stroke
Acute Subcutaneous SemaglutidE in Acute Ischemic sTroke
Can Semaglutide help reduce the damage caused by a stroke? ASSET trial is a national, multicenter, clinical trial, investigating the safety and efficacy of Semaglutide in non-diabetic patients with acute ischemic stroke.
- Trial name
- ASSET (NCT05630586)
- Testing
- Semaglutide, Standard care
- Where
- Denmark
- Volunteers
- 380 people
- Sponsor
- Aarhus University Hospital