Clinical trials: Acute Ischemic Stroke Patients
TIA, Stroke
Evaluation of the HARM for the Detection of a Cerebral Ischemia in TIA/TNA Patients
The research project investigates the incidence of the hyperintense acute reperfusion marker (HARM) in patients with transient ischemic attack (TIA) or transient neurological attack (TNA).
- Conditions
- TIA, Stroke, Ischemia, Diagnoses Disease
- Trial name
- NCT03555643
- Where
- Germany
- Volunteers
- 96 people
- Sponsor
- Universitätsmedizin Mannheim
Cerebral Ischemia, Cerebral Infarction
Efficacy of Sovateltide (PMZ-1620) in Patients of Acute Ischemic Stroke
In the present prospective, multicentric, randomized, double-blind, parallel, saline-controlled phase II clinical study; the investigators plan to evaluate the efficacy of sovateltide (IRL-1620 or PMZ-1620) therapy along with…
- Conditions
- Cerebral Ischemia, Cerebral Infarction, Stroke, Acute
- Trial name
- NCT04047563
- Testing
- Normal Saline along with standard treatment, PMZ-1620 (sovateltide) along with standard treatment
- Where
- 11 sites in India
- Volunteers
- 158 people
- Sponsor
- Pharmazz, Inc.
Stroke, Acute, Middle Cerebral Artery Stroke
Study of Human Placenta-derived Cells (PDA001) to Evaluate the Safety and Effectiveness for Patients With Ischemic Stroke
The primary objective of the study is to assess the safety and tolerability of Human Placenta-Derived Cells (PDA001) at 3 different dose levels versus placebo (vehicle control) administered intravenously in subjects following…
- Conditions
- Stroke, Acute, Middle Cerebral Artery Stroke, Posterior Cerebral Artery Stroke
- Trial name
- NCT01310114
- Testing
- Human Placenta-Derived Cells PDA001- (cenplacel-L)
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Celularity Incorporated
Acute Ischemic Stroke
An fNIRS Study of Motor Cortical Activation in Stoke Patients
The investigators evaluate the activation and connectivity of patients' motor regions in the acute phase of ischemic stroke by fNIRS.
- Trial name
- NCT05376098
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Xuanwu Hospital, Beijing
Ischemic Stroke, Cortisol; Hypersecretion
Neuroactive Steroids in Acute Ischemic Stroke
Acute ischemic stroke (AIS) represents an economical challenge for health systems all over the globe. Despite increasing knowledge of the pathophysiology of AIS, there is no satisfactory treatment to revert the resulting brain…
- Trial name
- Cortisol (NCT03242304)
- Testing
- Behavioral tests
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hospital Militar Central, Argentina
Ischemic Stroke, Acute
Innovative Technologies in Restoring Gait and Balance Funtions in Ischemic Stroke Patients at the Inpatient Stage
The scientific hypothesis was based on data on the effectiveness of the usage of robotic mechanotherapy and virtual reality technologies.
- Trial name
- NCT05423626
- Testing
- technologies of robotic mechanotherapy with FES, biofeedback virtual reality technologies
- Where
- Russia
- Volunteers
- 120 people
- Sponsor
- Moscow Scientific and Practical Center of Medical Rehabilitation, Restorative and Sports Medicine
Atrial Fibrillation, Stroke
China Atrial Fibrillation Screening in Acute Ischemic Stroke Patients
Three purpose of this study: 1. Increase diagnosis rate and formulate the flow of diagnosis and treatment of AF in ischemic stroke patients; 2. Evaluation on specificity and sensitivity of STAF score; 3.
- Trial name
- CRIST (NCT02156765)
- Where
- China
- Volunteers
- 3,000 people
- Sponsor
- yongjun wang
Acute Ischemic Stroke
Safety Of A Second Dose Of Tenecteplase In Selected Acute Ischemic Stroke Patients Not Responding To The First Dose
In this pilot safety study, the investigators will give a second dose of Intravenous Tenecteplase (IV TNK) to patients receiving the initial TNK dose within 3 hrs of last known normal (LKN), have a baseline National Institutes of…
- Trial name
- DoubleDoseTNK (NCT06801054)
- Testing
- Tenecteplase (TNK) (0.25 mg/kg, to maximum of 25mg)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Memorial Hermann Health System
Ischemic Stroke, Anticoagulant Adverse Reaction
Evaluataion of NOAC Levels in Acute Stroke
Non-vitamin K antagonist oral anticoagulants (NOACs) are recommended over warfarin in preventing stroke and thromboembolism among patients with atrial fibrillation (AF) in several guidelines.
- Trial name
- NCT06144866
- Testing
- Dabigatran, rivaroxaban, apixaban, edoxaban
- Where
- Taiwan
- Volunteers
- 1,000 people
- Sponsor
- National Taiwan University Hospital
Infarction, Middle Cerebral Artery
Study of Autologous Stem Cell Transplantation for Patients With Ischemic Stroke
This is a open label study to assess the safety of autologous bone marrow transplantation in patients with a ischemic stroke in the middle cerebral artery territory within 90 days from symptoms onset.
- Trial name
- NCT00473057
- Testing
- Autologous cell transplantation
- Where
- Brazil
- Volunteers
- 12 people
- Sponsor
- Universidade Federal do Rio de Janeiro
Stroke, Hyperglycemia
Glucose Regulation in Acute Stroke Patients (GRASP) Study
The purpose of this study is to assess the feasibility, safety and preliminary efficacy of the use of insulin infusions as treatment for hyperglycemic acute ischemic stroke patients.
- Trial name
- NCT00282867
- Testing
- IV glucose insulin and potassium, GIK, standard care
- Where
- 2 sites in United States
- Volunteers
- 74 people
- Sponsor
- University of Virginia
Acute Ischemic Stroke
Efficacy and Safety of the KPCXM18 Injection in Patients With Acute Ischemic Stroke
This study is a multicenter, randomized, double-blind, parallel, placebo-controlled trial design to evaluate the efficacy and safety of the KPCXM18 injection at different doses for the treatment of acute ischemic stroke.
- Trial name
- KPCXM18 (NCT07279493)
- Testing
- The KPCXM18 injection
- Where
- 23 sites in China
- Volunteers
- 300 people
- Sponsor
- Kunming Pharmaceuticals, Inc.
Stroke, Ischemic, Stroke, Acute
Comparison Between Unihemispheric and Bihemispheric TCDS in Subacute Ischemic Stroke Patients
This is a randomized clinical trial to study the effect of tDCS in participants with subacute ischemic stroke, the study participants will be randomly assigned into three groups; bihemispheric, unihemispheric and sham group.
- Conditions
- Stroke, Ischemic, Stroke, Acute, Stroke, Lacunar, Hemiparesis
- Trial name
- NCT04770363
- Testing
- Transcranial Direct Current Stimulation (tDCS)
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- Alexandria University
Transient Ischemic Attack
Incidence of Paroxysmal Atrial Fibrillation (AF) in Patients With Acute Ischemic Stroke or Transient Ischemic Attacks (TIAs) by 48 Hours Holter Monitoring
200 patients presenting with symptoms of acute ischemic stroke or transient ischemic attack were included. All patients free of AF on presentation underwent 48 hours Holter monitoring within one week.
- Trial name
- NCT04679987
- Testing
- Holter ECG
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Helwan University
Acute Ischemic Stroke
Prognostic Prediction Model of Patients With AcUte Stroke undeRgoing EndOvascular TheRApy (AURORA)
Stroke is the leading cause of disability-adjusted life years (DALYs) in China, imposing a heavy burden on society and families.
- Trial name
- AURORA (NCT06009315)
- Where
- China
- Volunteers
- 949 people
- Sponsor
- Beijing Tiantan Hospital
Ischemic Stroke, Acute Stroke
The Imperative Trial: Treatment of Acute Ischemic Stroke With the Zoom Reperfusion System
The trial is designed to assess the safety and efficacy of using the Zoom Reperfusion System in subjects diagnosed with acute ischemic stroke and undergoing a thrombectomy procedure within 8 hours of last known well.
- Trial name
- NCT04129125
- Testing
- Zoom Reperfusion System
- Where
- 28 sites in United States
- Volunteers
- 328 people
- Sponsor
- Imperative Care, Inc.
Stroke, Ischemic
Effects of Cognitive Exercises With Sensory Motor Relearning Program on Upper Limb Function in Sub-Acute Stroke Patients
The goal of this clinical trial is to compare the effects of cognitive sensory motor relearning, and sensory-motor relearning program alone on manual ability, sensation, gross and fine movements, and cognition in post-stroke…
- Trial name
- NCT06130891
- Testing
- Cognitive sensory motor relearning, Sensory motor relearning, Motor Relearning
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- Riphah International University
Ischemic Stroke, Covid19
Acute Revascularization Treatment in Ischemic Stroke Patients With COVID-19
Case-series and cohort studies have shown the feasibility of reperfusion therapies in patients with ischemic stroke and COVID-19, but due to the absence of a contemporary control group of non-COVID-19 patients, small sample size…
- Trial name
- NCT04895462
- Where
- Switzerland
- Volunteers
- 15,128 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Respiratory Virus Infection, Stroke
Respiratory Virus Infections in Acutely Hospitalized Adult Patients With Pulmonary and Extrapulmonary Complications
Respiratory virus infections are one of the major causes of hospitalizations, and outbreaks of respiratory virus infection have led to severe economic loss.
- Conditions
- Respiratory Virus Infection, Stroke, Lung Disease, Acute Coronary Syndrome
- Trial name
- NCT03816059
- Testing
- Respiratory virus testing
- Where
- Hong Kong
- Volunteers
- 200 people
- Sponsor
- The University of Hong Kong
Cerebrovascular Accident
Safety Study of a Recombinant Human Plasminogen Activator to Treat Acute Ischemic Stroke.
To evaluate the safety profiles of HTU-PA in patients with acute ischemic stroke.
- Trial name
- NCT00418275
- Testing
- Recombinant Human Plasminogen Activator (HTUPA)
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Global Biotech