Clinical trials: Acute Kidney Injury Following Cardiac Surgery
Acute Kidney Injury, Immune Deficiency
Immunoparalysis in Acute Kidney Injury After Cardiac Surgery
Infection and sepsis are common after acute kidney injury (AKI) and increase mortality. In this study, the investigators will determine whether patients with acute kidney injury after cardiac surgery have immunosuppression as…
- Trial name
- NCT03922958
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Colorado, Denver
Postoperative Acute Kidney Injury
Correlation Between Monitoring Renal Hemodynamics by Esophageal Ultrasound and Acute Kidney Injury After Heart Surgery
Acute kidney injury (AKI) is a common complication of cardiac surgery, which seriously affects the postoperative complication rate and mortality of patients.Acute kidney injury occurs in 5-30% of patients after cardiac surgery…
- Trial name
- NCT03798067
- Volunteers
- 60 people
- Sponsor
- Xuzhou Medical University
Acute Renal Injury
Acute Renal Injury After Major Elective Non-Cardiac Surgery
The study is planned to be a single-center study and includes patients who underwent major surgery within Istanbul University Istanbul Faculty of Medicine with an invasive arterial line.
- Trial name
- NCT04600271
- Testing
- Crystalloid Solutions, Colloid Blood Volume Expanders, blood replacement
- Where
- Turkey (Türkiye)
- Volunteers
- 425 people
- Sponsor
- Istanbul University
Acute Kidney Injury, Acute Renal Failure
Acute Kidney Injury After Cardiac Surgery: Novel Ultrasound Techniques for Prediction of Acute Kidney Injury
Acute Kidney Injury (AKI) is a frequent and important complication to cardiac surgery. This study will evaluate the diagnostic ability of ultrasonographic measures of blood flow in kidneys and liver in predicting AKI after…
- Conditions
- Acute Kidney Injury, Acute Renal Failure, Cardiac Surgery
- Trial name
- NCT03727204
- Testing
- On-pump cardiac surgery
- Where
- 2 sites in Denmark, South Africa
- Volunteers
- 150 people
- Sponsor
- Aarhus University Hospital
Liver Neoplasm, Kidney Injury, Acute
Perioperative Myocardial and Renal Injury in Patients Undergoing Hepatic Resection
Liver surgeries are high risk surgeries that might result in injuries in kidneys and heart. This study was planned to investigate the frequency of these injuries as well as the risk factors for their devolopment and its effect on…
- Conditions
- Liver Neoplasm, Kidney Injury, Acute, Myocardial Injury After Non-Cardiac Surgery
- Trial name
- NCT06775158
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people
- Sponsor
- Istanbul Saglik Bilimleri University
Acute Kidney Injury, Cardiac Surgery
Prediction of Acute Kidney Injury After Cardiac Surgery With Cardiopulmonary Bypass
Acute kidney injury (AKI) is a common and serious complication following cardiac surgery performed under cardiopulmonary bypass and is associated with increased morbidity, mortality, and prolonged hospital stay.
- Conditions
- Acute Kidney Injury, Cardiac Surgery, Cardiopulmonary Bypass Surgery, Cardiac Surgery Associated - Acute Kidney Injury
- Trial name
- AKI-CPB (NCT07343830)
- Where
- Turkey (Türkiye)
- Volunteers
- 455 people
- Sponsor
- Ataturk University
Acute Kidney Injury
Acute Kidney Injury After Cardiac Surgery
The investigators seek to determine whether a reduced preoperative renal functional reserve predicts postoperative acute kidney injury in patients with normal estimated glomerular filtration rates undergoing elective cardiac…
- Trial name
- NCT03457987
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- University of Giessen
Patients Undergoing Valvular Heart Surgery
Relationship Between Postoperative Tempeartive and Acute Kidney Injury
The investigators aimed to identify body temperature trajectory classes based on core temperature changes during the first 12 hours post-surgery and to explore their relationship with postoperative acute kidney injury in patients…
- Trial name
- NCT06647771
- Where
- South Korea
- Volunteers
- 3,274 people
- Sponsor
- Yonsei University
Acute Kidney Injury
Acute Kidney Injury Following Cardiac Surgery
Acute kidney injury (AKI) occurs in approximately one-third of patients undergoing cardiac surgery (CS), and represents one of the most significant negative predictors of patient outcome in this population.
- Trial name
- NCT03102528
- Testing
- No intervention
- Volunteers
- 495 people
- Sponsor
- University of Giessen
Intraoperative Hypotension, Acute Kidney Injury
Non-invasive Measurement of the Hypotension Prediction Index for the Reduction of Intraoperative Hypotension
In order to reduce the incidence of IOH, various goal-directed therapy (GDT) protocols have already been introduced with success regarding the reduction of postoperative AKI and MINS.
- Conditions
- Intraoperative Hypotension, Acute Kidney Injury, Myocardial Injury After Non-cardiac Surgery
- Trial name
- Clearsight (NCT06291714)
- Testing
- GDT-based hemodynamic management based on Clearsight device
- Where
- Germany
- Volunteers
- 150 people
- Sponsor
- University of Giessen
Magnesium Disorder
The Relationship Between Preoperative Levels of Ionized Magnesium and Risk of Acute Kidney Injury After Cardiac Surgery
Detection the relationship between preoperative ionized magnesium levels and the risk of acute kidney injury after cardiac surgery.
- Trial name
- NCT05903677
- Testing
- magnesium levels
- Volunteers
- 50 people
- Sponsor
- Assiut University
Acute Kidney Injury
Goal Direct Therapy to Prevent Acute Kidney Injury
This is an randomised controlled trial to investigate an strategy based in a protocol in prevention of acute kidney injury after cardiac surgery.
- Trial name
- GDT-AKI (NCT02396901)
- Testing
- Goal Direct Therapy
- Volunteers
- 214 people
- Sponsor
- University of Sao Paulo
Cardiac Surgery, Aortocoronary Bypass
Remote Ischemic Preconditioning After Cardiac Surgery
Acute kidney injury (AKI) is a well-recognized complication after cardiac surgery with cardiopulmonary bypass (CPB). The aim of this study is to reduce the incidence of AKI by implementing remote ischemic preconditioning and to…
- Trial name
- RIPCRenal (NCT02997748)
- Testing
- Remote ischemic preconditioning (RIPC)
- Where
- Germany
- Volunteers
- 180 people
- Sponsor
- University Hospital Muenster
Systemic Inflammatory Response Syndrome
INFLACOR - Clinical and Genetic Predictors of Inflammation Related Complications After Heart Surgery
The aim of the study is to evaluate a clinically and economically most effective diagnostic algorithm for prediction of inflammatory response related complications in patients undergoing heart surgery with use of cardiopulmonary…
- Trial name
- INFLACOR (NCT01020409)
- Testing
- cardiac surgery with CPB use
- Where
- Poland
- Volunteers
- 525 people, healthy volunteers welcome
- Sponsor
- Medical University of Gdansk
Cardiac Surgical Procedures, Extracorporeal Circulation; Complications
Acute Kidney Injury After Cardiac Surgery
PrimECC is a colloid priming solution for cardiopulmonary bypass/ extracorporeal circulation (ECC) based on Ringers Lactate, supplmeneted with Dextran 40 and Dextran 1.
- Conditions
- Cardiac Surgical Procedures, Extracorporeal Circulation; Complications, Acute Kidney Injury
- Trial name
- NCT04293744
- Testing
- Colloid priming solution for ECC circuit, Standard priming solution for ECC circuit
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- XVIVO Perfusion
Cardiac Surgical Procedures
Diagnostic Accuracy of Doppler Resistive Indices for Early Diagnosis of Acute Kidney Injury .
To determine if ultrasound measurement of renal and carotid arterial resistive indices are associated with post-cardiac surgery acute kidney injury.
- Trial name
- NCT02580292
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Michigan
Machine Learning, Acute Kidney Injury
Machine Learning Predict Renal Replacement Therapy After Cardiac Surgery
Cardiac surgery-associated acute kidney injury (CSA-AKI) is a major complication which may result in adverse impact on short- and long-term mortality.
- Conditions
- Machine Learning, Acute Kidney Injury, Renal Replacement Therapy, Prediction Models
- Trial name
- NCT04977687
- Where
- China
- Volunteers
- 2,108 people
- Sponsor
- Chinese PLA General Hospital
Acute Kidney Injury
Early Versus Late Renal Replacement Therapy After Cardiac Surgery
The question of timing of initiation of renal replacement therapy (RRT), "early" versus "late", has seldom been the focus of high-quality or rigorous evaluation.
- Trial name
- NCT01961999
- Testing
- Early RRT, Late RRT
- Where
- Italy
- Volunteers
- 1,800 people
- Sponsor
- Ospedali Riuniti Ancona
Kidney Failure, Acute, Acute Kidney Insufficiency
Minocycline to Prevent Acute Kidney Injury After Cardiac Surgery
This study proposes to investigate whether treatment with minocycline pre-operatively in patients with mild to moderate chronic kidney disease undergoing cardiac surgery will reduce the occurence of kidney injury.
- Trial name
- NCT00556491
- Testing
- minocycline
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- Tarek M. El-Achkar
Acute Kidney Injury, Acute Kidney Disease
Effect of CVP and IOH on AKI and AKD
This study was aimed to explore the effect of intraoperative venous congestion and intraoperative hypotension (IOH) on acute adverse kidney events, defined as acute kidney injury (AKI) and acute kidney disease (AKD), after…
- Trial name
- NCT05222074
- Testing
- Venous congestion, Introperation hypotension
- Where
- China
- Volunteers
- 5,127 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University