Clinical trials: Acute Malnutrition
Sickle Cell Disease, Anemia, Sickle Cell
Daily Vitamin D for Sickle-cell Respiratory Complications
This study aims to answer the question whether daily oral vitamin D supplementation can reduce the risk of respiratory or lung complications in children and adolescents with sickle cell disease.
- Conditions
- Sickle Cell Disease, Anemia, Sickle Cell, Anemia, Hemolytic, Congenital, Respiratory Tract Diseases
- Trial name
- ViDAS-2 (NCT04170348)
- Testing
- Daily oral vitamin D3, 3,333 IU, Monthly oral vitamin D3, 100,000 IU
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- Columbia University
Malaria, Diarrhea
Liberia National Community Health Assistant (NCHA) Program and Under-five Mortality
Last Mile Health (LMH) has partnered with the Liberian Ministry of Health (MOH) to support the design and implementation of the National Community Health Assistant Program (NCHAP).
- Conditions
- Malaria, Diarrhea, Acute Respiratory Infection, Malnutrition, Child
- Trial name
- NCT05123378
- Testing
- Liberia National Community Health Assistant Program
- Where
- Liberia
- Volunteers
- 23,702 people, healthy volunteers welcome
- Sponsor
- Last Mile Health
Severe Acute Malnutrition
Rice Bran-based Supplemental Foods for the Treatment of Childhood Malnutrition
The purpose of this study is to assess the efficacy of treating children with severe acute malnutrition (SAM) with a locally produced ready-to-use therapeutic food (RUTF) with or without rice bran.
- Trial name
- NCT05319717
- Testing
- Ready-to-use therapeutic food with heat stabilized rice bran, Ready-to-use therapeutic food (no rice bran)
- Where
- Indonesia
- Volunteers
- 200 people
- Sponsor
- Colorado State University
Diarrhea, Dehydration
Zinc-ORS in Severe and Complicated Acute Diarrhea
Three-hundred-and-fifty-two males aged 1-36 months with acute non-dysenteric diarrhoea and no systemic illness will be enrolled in this clinical trial.
- Trial name
- NCT00370968
- Testing
- Zinc sulphate
- Where
- 2 sites in India
- Volunteers
- 352 people
- Sponsor
- Centre For International Health
Leukemia, Lymphoma
Cyproheptadine Hydrochloride and Nutritional Supplementation in Treating Young Patients With Weight Loss With Cancer
RATIONALE: Cyproheptadine hydrochloride may help improve appetite and lessen weight loss caused by cancer or cancer treatment. It is not yet known whether cyproheptadine hydrochloride is more effective with or without nutritional…
- Conditions
- Leukemia, Lymphoma, Malnutrition, Myelodysplastic Syndromes
- Trial name
- NCT00949117
- Testing
- Ensure, PediaSure, cyproheptadine hydrochloride
- Volunteers
- 9 people
- Sponsor
- University of South Florida
Stroke, Acute, Malnutrition
The Effect of Nutrition Counseling on Nutritional Status in Stroke Patients
The purpose of this study is to investigate the effect of intensive nutrition counseling on nutritional status and functional recovery in stroke patients over the age of 65, compared to standard nutrition counseling.
- Conditions
- Stroke, Acute, Malnutrition, Old Age; Debility
- Trial name
- NCT06208969
- Testing
- intensive nutrition counseling
- Where
- Turkey (Türkiye)
- Volunteers
- 61 people
- Sponsor
- Ege University
Kwashiorkor
The Role of Sulfur Amino Acids in Risk of Kwashiorkor
This observational cross-sectional study is investigating if young children in populations with higher prevalence of kwashiorkor malnutrition have lower dietary sulfur amino acid intake than populations with lower prevalence of…
- Trial name
- NCT03520621
- Testing
- No intervention
- Where
- Democratic Republic of the Congo
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Tufts University
Severe Acute Malnutrition, Moderate Acute Malnutrition
Family Mid-Upper Arm Circumference (MUAC) Follow-up After Recovery From Acute Malnutrition (MODAM-fMUAC)
Protocols for the community-based management of acute malnutrition (CMAM) have not changed significantly for more than 20 years, with relatively complex treatment protocols and persistent supply chain challenges that have limited…
- Trial name
- MODAM-fMUAC (NCT06038071)
- Testing
- nutrition, IYCF, WASH education, scheduled anthropometric screening, family MUAC
- Where
- 3 sites in Ethiopia
- Volunteers
- 3,600 people
- Sponsor
- Action Against Hunger USA
Malnutrition or Risk of Malnutrition, Acute Respiratory Failure
Nutritional Intake in Patients on Noninvasive Ventilation: a Prospective Observational Study
The primary objective is to quantify the caloric and protein intake in adult participants with acute respiratory failure who start a noninvasive ventilation treatment.
- Trial name
- PRO-NUTRINIV (NCT06740981)
- Testing
- Food diary
- Where
- Italy
- Volunteers
- 126 people
- Sponsor
- Università degli Studi del Piemonte Orientale Amedeo Avogadro
Malnutrition; Moderate
Effectiveness, Tolerability and Safety of Three Formulations in Underfives With Moderate Acute Malnutrition
This is a randomized clinical trial aimed at evaluating the effectiveness, tolerability and safety of standardized milk-based formulation, standardized non-milk based formulation and a hospital-based formulation in the management…
- Trial name
- NCT04323059
- Testing
- Standardized milk-based formulation
- Where
- 3 sites in Nigeria
- Volunteers
- 80 people
- Sponsor
- Dr. Ekong E. Udoh
Malnutrition Severe, Vaccination
OptiMAx Will Test Whether SQ-LNS Incentivises Vaccination Uptake in Rural Chad and Niger, With a Cost Effectiveness Analysis. It Will Also Look at Whether Having Received SQ-LNS Before Becoming Malnourished Leads to Better Outcomes for Children Treated Under the OptiMA Protocol.
Malnutrition and infectious disease form a vicious circle, posing a double threat to vulnerable children in low- and middle-income countries.
- Trial name
- OptiMAx (NCT07592260)
- Testing
- small quantity lipid-based supplement (SQ-LNS)
- Where
- 2 sites in Chad, Niger
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Alliance for International Medical Action
Acute Malnutrition in Childhood
Effectiveness of Local Food Solutions for the Prevention of Acute Malnutrition in Tigray, Northern Ethiopia (ELOFSAM)
The lack of diversified and enriched complementary foods is one of the key causes of the high burden of acute malnutrition among 6-23 months old children in Ethiopia.
- Trial name
- ELOFSAM (NCT06103084)
- Testing
- Bahgina, SQLNS
- Where
- Ethiopia
- Volunteers
- 7,530 people, healthy volunteers welcome
- Sponsor
- Mekelle University
Acute Myeloid Leukemia, Leukemia, Myeloid
Studying Malnutrition And Sarcopenia In Older Adults With Acute Myeloid Leukemia
This study will explore how malnutrition (poor nutrition/diet) and sarcopenia (a condition that causes a loss of muscle and bone mass) affects study participants over the age of 60 with acute myeloid leukemia (AML) who will…
- Trial name
- NCT05458258
- Testing
- Bioelectrical Impedence Analysis Device, 6 Minute Walk Test, Computed Tomography Scans to Measure Skeletal Muscular Index
- Where
- United States
- Volunteers
- 239 people
- Sponsor
- University of Chicago
Acute Malnutrition in Childhood, Acute Malnutrition, Severe
The Relapse to Acute Malnutrition Prevention (RAMP) Trial
This individually randomized controlled trial uses a 2x2 factorial design to evaluate the effects of azithromycin and small-quantity lipid-based nutrient supplements (SQ-LNS) on sustained nutritional recovery following initial…
- Trial name
- RAMP (NCT07871955)
- Testing
- Azithromycin, Small-quantity Lipid-based Nutrient Supplements
- Where
- South Sudan
- Volunteers
- 3,750 people
- Sponsor
- Action Against Hunger USA
Acute Lymphoblastic Leukemia, Vitamin d Deficiency
Effect of Supplementation With ω-3 Fatty Acids, Vitamin D and Calcium in Patients With Acute Lymphoblastic Leukemia.
The purpose of this study is to evaluate the efficacy of supplementation with Omega 3, Vitamin D and Calcium, in a cohort of children with ALL undergoing treatment and compare changes in the concentrations of biomarkers of bone…
- Trial name
- NCT05950204
- Testing
- ω-3 polyunsaturated fatty acids (DHA and EPA), Vitamin D (cholecalciferol), Calcium (calcium carbonate)
- Where
- Mexico
- Volunteers
- 40 people
- Sponsor
- Coordinación de Investigación en Salud, Mexico
Clinically Severe Obesity, Metabolic Complications After Jejunoileal Bypass
Laparoscopic Revision of Jejunoileal Bypass to Gastric Bypass
This study objectives are the following. To describe the updated clinical presentation, indications, and multidisciplinary medical management of patients with a failed and/or complicated jejunoileal bypass (JIB).
- Conditions
- Clinically Severe Obesity, Metabolic Complications After Jejunoileal Bypass, Nutritional Complications After Jejunoileal Bypass, Obesity Recidivism
- Trial name
- JIB-to-RYGB (NCT01040533)
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of California, San Francisco
Newborn Resuscitation, Severe Malnutrition
Enhancing Pediatric Acute Care Through Adaptive E-Learning and In-Person Skills Practice in Tanzania
The goal of this clinical trial is to evaluate whether the integration of in-person skills practice (ISP) with an adaptive e-learning platform can improve refresher learning progress (RLP) among healthcare providers in pediatric…
- Conditions
- Newborn Resuscitation, Severe Malnutrition, Severe Malaria, Severe Pneumonia
- Trial name
- PACE (NCT06635733)
- Testing
- Rhapsode Capable™ Platform (Intervention Group), Paper-based ISP (Control Group)
- Where
- Tanzania
- Volunteers
- 100 people
- Sponsor
- Stanford University
Acute Lymphoblastic Leukemia
Nutritional Status in Children With ALL in Guatemala
This study proposes to investigate the association of nutritional status of a children assessed by body mass index (BMI), triceps skinfold thickness (TSFT), and mid upper arm circumference (MUAC), with body composition, measured…
- Trial name
- NCT03471416
- Where
- Guatemala
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Columbia University
Protein Malnutrition
Comparison of Clinical Outcomes According to High-protein Provision in Critically Ill Patients After Abdominal Surgery
Protein malnutrition in critically ill patients is a global concern due to its association with prolonged hospital stays, and higher morbidity rates.
- Trial name
- NCT06458387
- Testing
- Active protein supplementation, Conventional protein supplementation
- Where
- South Korea
- Volunteers
- 152 people
- Sponsor
- Seoul St. Mary's Hospital
Moderate Acute Malnutrition (MAM)
Comparison of Four Different Supplementary Foods in the Treatment of Moderate Acute Malnutrition (MAM) in Children in Sierra Leone: a Cluster-randomised, Controlled Clinical Effectiveness Trial
The objective of this study is to test and compare the effectiveness and cost-effectiveness of four supplementary foods for the treatment of moderate acute malnutrition (MAM) in normal programmatic settings in Sierra Leone.
- Trial name
- NCT02077907
- Testing
- Super Cereal Plus (SC+), Super Cereal (SC), fortified oil, sugar, Plumpy Sup
- Volunteers
- 1,147 people, healthy volunteers welcome
- Sponsor
- Tufts University