Clinical trials: Acute Myocardial Infarction, completed
Myocardial Infarction, Heart Failure
Omega-3 Fatty Acids in Elderly Patients With Acute Myocardial Infarction
The aim of the present study is to investigate the possible effects of supplementation with 1.8 g/day of n-3 polyunsaturated fatty acids on cardiovascular morbidity and mortality during a follow-up period of 2 years in an elderly…
- Conditions
- Myocardial Infarction, Heart Failure, Myocardial Revascularization, Atrial Fibrillation
- Trial name
- OMEMI (NCT01841944)
- Testing
- Pikasol, Corn oil
- Where
- 4 sites in Norway
- Volunteers
- 1,027 people
- Sponsor
- Oslo University Hospital
Acute Myocardial Infarction
A Pilot Study of Transcoronary Myocardial Cooling
Patients with heart attacks caused by blocked coronary arteries are usually treated with a technique called primary angioplasty.
- Trial name
- NCT02312336
- Testing
- Cohort A - Room temperature coronary perfusate, Cohort B - Cooled coronary perfusate
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
Acute ST Elevation Myocardial Infarction
The Efficacy and Safety of rhTNK-tPA in Comparison With Alteplase(Rt-PA) as Fibrinolytic Therapy of Acute STEMI
This study is aiming to test the hypothesis that efficacy of rhTNK-tPA was not inferior to rt-PA with respect to the 30-day MACCE rates after fibrinolytic therapy for STEMI patients.
- Trial name
- NCT02835534
- Testing
- rhTNK-tPA, alteplase
- Where
- China
- Volunteers
- 818 people
- Sponsor
- CSPC Mingfule Pharmaceutical (Guangzhou) Co., Ltd.
Acute Coronary Syndrom, Chronic Obstructive Pulmonary Syndrom
Pneumological Acute Coronary Syndrom (ACS) Phenotyping Aachen
In this open, monocentric, observational study acute coronary syndrom (ACS) patients will be characterized by pneumological examination concerning a concomitant chronic obstructive pulmonary disease (COPD).
- Trial name
- PAPA (NCT02587481)
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- RWTH Aachen University
Acute Myocardial Infarction
The Prognosis of Acute Myocardial Infarction
This study aims to establish a registry and surveillance system for acute myocardial infarction (AMI) patients in Xinjiang, focusing on collecting comprehensive information including basic patient demographics, patient…
- Trial name
- AMI-COPS (NCT02737956)
- Where
- China
- Volunteers
- 7,350 people
- Sponsor
- Xinjiang Medical University
Myocardial Infarction
Safety of TG100-115 for Heart Attack Treated With Angioplasty
TG100-115 is able to reduce the size of heart attacks in pre-clinical models. The hypothesis of this study is that TG100-115 can be given safely to patients who suffer a heart attack and undergo angioplasty to restore blood flow.
- Trial name
- NCT00103350
- Testing
- TG100-115
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- TargeGen
Myocardial Injury
Prospective Trial: Acute Myocardial Injury After Radical Prostatectomy
This prospective observational study investigates the incidence of acute myocardial injury after radical prostatectomy for prostate cancer.
- Trial name
- NCT06273735
- Testing
- Pre- and postoperative determination of troponin as part of the study and 24-month FU survey
- Where
- Germany
- Volunteers
- 1,000 people
- Sponsor
- Martini-Klinik am UKE GmbH
Acute Coronary Syndrome, Myocardial Infarction
High-Sensitivity Cardiac Troponin On Presentation to Rule Out Myocardial Infarction
Patients with suspected acute coronary syndrome account for a tenth of all presentations to the Emergency Department and up to 40 per cent of unplanned hospital admissions.
- Trial name
- HiSTORIC (NCT03005158)
- Testing
- Validation Phase, Randomization Phase, Implementation Phase
- Volunteers
- 31,492 people
- Sponsor
- University of Edinburgh
Myocardial Infarction
Effects of Early Statin Treatment After Acute Myocardial Infarction (AMI) in Japanese Patients
Statins have been shown to prevent coronary artery disease and to preserve left ventricular function in dilated cardiomyopathy. The investigators hypothesized that the early use of statins would reduce cardiovascular events…
- Trial name
- NCT00128024
- Testing
- lipid-lowering treatment
- Where
- Japan
- Volunteers
- 460 people
- Sponsor
- Kumamoto University
Acute Coronary Syndrome
A Comparison of Ticagrelor (AZD6140) and Clopidogrel in Patients With Acute Coronary Syndrome
Ticagrelor is a new, reversible binding, anti-platelet medication. Anti-platelet medications work to prevent the formation of blood clots.
- Trial name
- PLATO (NCT00391872)
- Testing
- Ticagrelor, Clopidogrel
- Where
- 672 sites in United States, Argentina and 42 more
- Volunteers
- 18,624 people
- Sponsor
- AstraZeneca
Acute Coronary Syndrome
Fondaparinux Trial With Unfractionated Heparin (UFH) During Revascularization in Acute Coronary Syndromes (ACS)
The purpose of this study is to compare the safety of two different dose regimens of unfractionated heparin (UFH) during a percutaneous coronary intervention (PCI) procedure in patients with UA (unstable angina)/NSTEMI (non ST…
- Trial name
- FUTURA/OASIS 8 (NCT00790907)
- Testing
- fondaparinux background and standard dose UFH, Fondaparinux background and low dose heparin, Open label fondaparinux
- Where
- 203 sites in United States, Argentina and 16 more
- Volunteers
- 3,235 people
- Sponsor
- GlaxoSmithKline
Acute Myocardial Infarction
Phase 1 Study of Potential Anti-Inflammatory Effects of Glucose Control During Acute Myocardial Infarction.
The purpose of this study is to determine if intense control of high glucose levels in patients treated with angioplasty for heart attack has anti-inflammatory and anti-thrombotic effects.
- Trial name
- NCT00209144
- Testing
- Intensive insulin therapy
- Where
- 2 sites in United States
- Volunteers
- 58 people
- Sponsor
- Emory University
Ventricular Septal Rupture, Papillary Muscle Rupture
Mechanical Complications of Acute Myocardial Infarction During COVID-19 Pandemics
The ongoing COVID-19 pandemics has put an overwhelming pressure on the healthcare systems of many European countries. Such a situation has potentially led to delayed and impaired access to appropriate treatment for patients…
- Conditions
- Ventricular Septal Rupture, Papillary Muscle Rupture, Free Wall Rupture, Heart
- Trial name
- CautionCov19 (NCT04813692)
- Testing
- Surgical repair, Percutaneous treatment, Mitral valve surgery
- Where
- Netherlands
- Volunteers
- 130 people
- Sponsor
- Maastricht University Medical Center
Myocardial Infarction
A Study to Investigate the Procoagulant Effect of Tenecteplase (TNK-tPA), Alteplase (Rt-PA) and Streptokinase (SK) Administered to Patients With Acute Myocardial Infarction (AMI)
Primary objective: to evaluate the procoagulant effect of TNK-tPA compared to rt-PA and streptokinase, administered to patients with AMI, by measuring the concentration of TAT at 2 hours after the start of treatment versus…
- Trial name
- NCT02182011
- Testing
- Tenecteplase, Alteplase, Streptokinase
- Volunteers
- 49 people
- Sponsor
- Boehringer Ingelheim
Myocardial Infarction
Antiplatelet Therapy Effect on Extracellular Vesicles in Acute Myocardial Infarction
Platelet activation and aggregation leads to myocardial infarction. Platelet P2Y12 receptors are essential for platelet activation.
- Trial name
- AFFECT EV (NCT02931045)
- Testing
- Ticagrelor, Clopidogrel
- Where
- 2 sites in Netherlands, Poland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Medical University of Warsaw
Acute Myocardial Infarction
Sevoflurane In Acute Myocardial Infarction
Ischemic postconditioning can reduce myocardial injury following myocardial infarction. A potential pharmacological agent is the anesthetic Sevoflurane.
- Trial name
- SIAMI (NCT00971607)
- Testing
- Oxygen + Sevoflurane
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Acute Coronary Syndrome, Contrast-Induced Acute Kidney Injury
Predictors of Contrast-induced Acute Renal Injury in Patients With Acute Coronary Syndrome
This observational study aims to identify predictors of contrast-induced acute kidney injury (CI-AKI) in patients with acute coronary syndrome undergoing percutaneous coronary intervention.
- Trial name
- PC-AKI-ACS (NCT07294911)
- Testing
- Observational data collection
- Where
- Kazakhstan
- Volunteers
- 88 people
- Sponsor
- Karaganda Medical University
Acute Myocardial Infarction
Heartstrong Pilot Program
This is a 6-month pilot study intended to test the effect of financial incentives on improving medication adherence in AMI patients; to test the effect on adherence of removing financial incentives; and to test the effect on the…
- Trial name
- NCT02139202
- Testing
- Social Influence, Electronic Pill Bottles, Financial Incentives
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- University of Pennsylvania
Chest Pain, Acute Myocardial Infarction
Risk Score Alerts for Chest Pain Care
The evaluation of chest pain in the primary care office is a challenging problem, with many patients suffering from missed diagnoses of acute myocardial infarction and many other low risk patients receiving unnecessary…
- Trial name
- NCT00674375
- Testing
- Electronic risk alerts
- Where
- 2 sites in United States
- Volunteers
- 8,000 people
- Sponsor
- Harvard Vanguard Medical Associates
Acute Coronary Syndrome
Re-hospitalized Patients With Acute Coronary Syndrome
The predictors of re-hospitalization of patients with history of acute coronary syndrome
- Trial name
- BoomerangACS (NCT03727984)
- Where
- Turkey (Türkiye)
- Volunteers
- 577 people
- Sponsor
- Cardiovascular Academy Society, Turkey