Clinical trials: Acute Myocardial Infarction, completed
Myocardial Infarction
Safety and Feasibility of Intracoronary Hypothermia in Acute Myocardial Infarction
Hypothermia may reduce infarct size in patients with acute myocardial infarction if provided before reperfusion. Human studies using systemic cooling methods failed to show a reduction in infarction size.
- Trial name
- SINTAMI (NCT02753478)
- Testing
- intracoronary infusion with saline on 22 and 4°C
- Where
- Netherlands
- Volunteers
- 10 people
- Sponsor
- Catharina Ziekenhuis Eindhoven
Myocardial Infarction, STEMI
A Smartphone APPlication for the Transmission of ECGs in the Management of Patients Presenting With Suspected Heart Attacks in the Hamilton, Niagara, Haldimand, and Brant Area
The delivery of timely and appropriate care is crucial for patients with heart attacks. Blocked arteries need immediate intervention to restore blood flow.
- Trial name
- NCT05290389
- Testing
- SMART AMI APPLICATION
- Where
- 17 sites in Canada
- Volunteers
- 260 people
- Sponsor
- McMaster University
Acute Myocardial Infarction, Heart Failure
Prognostic Value of Lung Ultrasound in ST Segment Elevation Acute Myocardial Infarction (LUS-AMI)
The purpose of this study is to asses the prognostic value of lung ultrasound in patients with ST-segment elevation acute myocardial infarction.
- Trial name
- LUS-AMI (NCT04526535)
- Testing
- Lung ultrasound
- Where
- 2 sites in Spain
- Volunteers
- 400 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Acute Myocardial Infarction
Impact of Guidelines on Cardiovascular and Economic Outcomes With Focus on Lipid Lowering Drugs
Methods: All patients <75 years registered in the Swedish Secondary Prevention after Heart Intensive care Admission registry (SEPHIA), will be followed-up within one year post-myocardia infarction (MI).
- Trial name
- GuLLD (NCT02929550)
- Testing
- Well-controlled
- Volunteers
- 5,304 people
- Sponsor
- Karolinska Institutet
Smoking, Myocardial Infarction
Bupropion for Hospitalized Smokers With Acute Cardiovascular Disease
The purpose of the study is to test the efficacy and safety of bupropion SR for smokers hospitalized with acute cardiovascular disease.
- Conditions
- Smoking, Myocardial Infarction, Unstable Angina, Cardiovascular Disease
- Trial name
- NCT00181818
- Testing
- bupropion SR (sustained-release)
- Where
- United States
- Volunteers
- 248 people
- Sponsor
- Massachusetts General Hospital
Acute Coronary Syndrome
Comparison Between the New Highly Sensitive Troponin T and the Conventional Troponin T Test in Elderly Patients
The planned cohort study shall clarify whether the use of biomarkers leads to improved diagnostic assessment of elderly patients.
- Trial name
- BOSCH2 (NCT01370382)
- Where
- Germany
- Volunteers
- 180 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Myocardial Infarction
Myocardial Stem Cell Administration After Acute Myocardial Infarction (MYSTAR) Study
The MYocardial STem cell Administration after acute myocardial infaRction (MYSTAR) study is a multicenter, prospective, randomized, single-blind clinical trial designed to compare the early and late intracoronary or combined…
- Trial name
- MYSTAR (NCT00384982)
- Testing
- Bone marrow-derived stem cells implantation
- Where
- Austria
- Volunteers
- 116 people
- Sponsor
- Medical University of Vienna
Acute Myocardial Infarction, Heart Failure
Anakinra to Prevent Adverse Post-infarction Remodeling (2)
Acute myocardial infarction (AMI) remains a major cause of morbidity and mortality. Many patients die early during the course, and those who survive are at risk for dying late from adverse cardiac remodeling and heart failure.
- Trial name
- VCU-ART2 (NCT01175018)
- Testing
- Anakinra
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Virginia Commonwealth University
Cardiovascular Diseases
A Randomized, Single-blind, Controlled Clinical Study of Cardiomyopeptidin on Improving Ischemia-reperfusion Injury in Patients With Acute ST-segment Elevation Myocardial Infarction After Primary PCI
This study aim to investigate the myocardium protection effect of cardiomyopeptidin in patients undergoing primary PCI for ST-elevation myocardial infarction through myocardial enhanced MRI.
- Trial name
- NCT06155110
- Testing
- cardiomyopeptidin
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Chinese PLA General Hospital
Acute Coronary Syndrome, Myocardial Infarction
RAMP 200 / RAMP Cardiovascular Tests at the Point-of-Care
This clinical investigation is designed to demonstrate the performance characteristics of the RAMP® cardiac tests analyzed on the RAMP® 200 by non-laboratorial Operators at the point-of-care when compared to the results for the…
- Conditions
- Acute Coronary Syndrome, Myocardial Infarction, Heart Failure, Congestive Heart Failure
- Trial name
- C-POC (NCT02191735)
- Testing
- RAMP 200, RAMP Reader
- Where
- 3 sites in United States
- Volunteers
- 719 people
- Sponsor
- Response Biomedical Corp.
Coronary Artery Disease, Acute Coronary Syndromes
Discovery of New Circulating Biomarkers of Coronary Atherosclerosis
The study hypothesis is that differential proteomic techniques can be used to discover new circulating biomarkers of coronary atherosclerosis in the blood of patients suffering from coronary artery disease (either stable or…
- Conditions
- Coronary Artery Disease, Acute Coronary Syndromes, Myocardial Infarction, Atherosclerosis
- Trial name
- NCT00430820
- Testing
- per intervention
- Where
- France
- Volunteers
- 124 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
ST-Elevation Myocardial Infarction
Myocardial Salvage Assessed by Cardiovascular Magnetic Resonance - Impact on Outcome
In acute myocardial infarction cardiovascular magnetic resonance imaging can retrospectively detect the myocardium at risk and the irreversible injury.
- Trial name
- NCT00952224
- Testing
- magnetic resonance imaging
- Where
- Germany
- Volunteers
- 267 people
- Sponsor
- University of Leipzig
Acute Coronary Syndrome
Usefulness of a 2-hour Delta Troponin-I During the ED Identification and Exclusion of Acute Myocardial Infarction
1. In chest pain patients with suspected acute coronary syndrome, a 2-hr delta Troponin-I as measured by the i-STAT immunoassay reliably identifies and excludes an acute myocardial infarction. 2.
- Trial name
- NCT02002546
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Chattanooga-Hamilton County Hospital Authority
Acute Heart Failure, Heart Failure
Dapagliflozin and Effect on Cardiovascular Events in Acute Heart Failure -Thrombolysis in Myocardial Infarction 68 (DAPA ACT HF-TIMI 68)
This is an international, multicenter, parallel-group, randomized, double-blind, placebo-controlled trial in patients who have been stabilized during hospitalization for acute heart failure, evaluating the effect of in-hospital…
- Trial name
- NCT04363697
- Testing
- Dapagliflozin
- Where
- United States
- Volunteers
- 2,401 people
- Sponsor
- The TIMI Study Group
Myocardial Infarction, Unstable Angina
The Impact of Gratitude on Biology and Behavior in Persons With Heart Disease
Overall, the investigators aim to recruit 150 subjects during their hospitalization for an acute coronary syndrome (ACS). At two weeks post-ACS, the investigators will assess levels of gratitude and optimism, draw blood for…
- Trial name
- GRACE (NCT01709669)
- Where
- United States
- Volunteers
- 212 people
- Sponsor
- Massachusetts General Hospital
Acute Coronary Syndrome, Percutaneous Coronary Intervention
A Trial of Trans-radial Versus Trans-femoral Percutaneous Coronary Intervention (PCI) Access Site Approach in Patients With Unstable Angina or Myocardial Infarction Managed With an Invasive Strategy
This is a multi-national, multi-centre, randomized study comparing the trans-radial PCI access strategy and the trans-femoral PCI access strategy in ACS patients with UA or NSTEMI or STEMI planned to be treated with an invasive…
- Trial name
- RIVAL (NCT01014273)
- Testing
- Percutaneous Coronary Intervention
- Where
- Canada
- Volunteers
- 7,021 people
- Sponsor
- Population Health Research Institute
Chest Pain, Coronary Artery Disease
ARgentinean Risk Assessment Registry in ACS; the ARRA-RACS Study
The first aim of this trial is to assess the long-term prognostic value of Omega-3 index, which is a measure of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) relative to other fatty acids in the erythrocyte membrane…
- Conditions
- Chest Pain, Coronary Artery Disease, Unstable Angina Pectoris, Myocardial Infarction
- Trial name
- ARRA-RACS (NCT01377402)
- Where
- 10 sites in Argentina, Norway
- Volunteers
- 982 people
- Sponsor
- Helse Stavanger HF
Familial Hypercholesterolemia, Familial Hypercholesterolemia Due to Genetic Defect of Apolipoprotein B
Advancing Cardiac Care Unit-based Rapid Assessment and Treatment of hypErcholesterolemia
ACCURATE will test the hypothesis that opportunistic genetic testing for Familial Hypercholesterolemia (FH) in patients admitted to hospital with an acute coronary syndrome will increase the diagnosis of FH and will impact…
- Conditions
- Familial Hypercholesterolemia, Familial Hypercholesterolemia Due to Genetic Defect of Apolipoprotein B, Familial Hypercholesterolemia Due to Heterozygous LDL Receptor Mutation, Familial Hypercholesterolemia - Heterozygous
- Trial name
- ACCURATE (NCT05218005)
- Testing
- Research-based genetic test for Familial Hypercholesterolemia
- Where
- 2 sites in Canada
- Volunteers
- 140 people
- Sponsor
- University of British Columbia
Stable Angina, Unstable Angina
Clinical Performance of CRE8 Drug Eluting Stent in All Comer Population
The aim of this study is to evaluate safety and efficacy performances of CRE8 Drug Eluting Stent, in patients comparable to the everyday's clinical practice population, with a specific focus on diabetics, that will be part of a…
- Conditions
- Stable Angina, Unstable Angina, Acute Myocardial Infarction
- Trial name
- PARTICIPATE (NCT01556126)
- Testing
- Amphilimus Eluting Stent (CRE8)
- Where
- 23 sites in Austria, Belgium and 4 more
- Volunteers
- 1,191 people
- Sponsor
- CID - Carbostent & Implantable Devices
ACS, NSTEMI - Non-ST Segment Elevation MI
Prehospital Triage of Patients With Suspected Non-ST-segment Elevation Acute Coronary Syndrome: the TRIAGE-ACS Study
With the Emergency Medical Services (EMS), no prehospital risk stratification and triage is performed for patients suspected of having an Non-ST-segment elevation Acute Coronary Syndrome (NSTE-ACS).
- Conditions
- ACS, NSTEMI - Non-ST Segment Elevation MI, Unstable Angina
- Trial name
- NCT05243485
- Testing
- PreHEART
- Where
- Netherlands
- Volunteers
- 1,071 people
- Sponsor
- Catharina Ziekenhuis Eindhoven