Clinical trials: Acute Myocardial Infarction, completed
ST Elevation Acute Myocardial Infarction
Myocardial Function Recovery Prediction Post Primary PCI Using the Estimate of Myocardial Salvage in Gated SPECT Early After Acute Myocardial Infarction
Our aim was to correlate functional and perfusion abnormalities early post primary percutaneous coronary intervention after acute myocardial infarction in ST elevation myocardial infarction patients to estimate myocardial…
- Trial name
- NCT07568587
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Fayoum University
Coronary Artery Disease, Endothelial NO-synthase
Regulation and Signaling of Red Blood Cell (RBC) Endothelial Nitric Oxide Synthase (eNOS) in Patients With Stable and Unstable Coronary Artery Disease
The aim of this study is measurement of expression and activity of RBC eNOS in different clinical cohorts of patients with coronary artery disease and acute coronary syndrome and to investigate the importance of the NO-stimulated…
- Trial name
- NCT02265016
- Where
- Germany
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Heinrich-Heine University, Duesseldorf
Acute Coronary Syndrome, Non-ST-Elevation Myocardial Infarction
Risk Stratification of Non ST Elevation ACS With Computed Tomographic Angiography (REACT)
The purpose of this project is to examine the effectiveness of computed tomographic angiography (CTA) in patients with non-ST elevation acute coronary syndrome (NSTE-ACS).
- Conditions
- Acute Coronary Syndrome, Non-ST-Elevation Myocardial Infarction, Unstable Angina
- Trial name
- NCT00449826
- Testing
- Computed Tomographic Angiography
- Where
- Canada
- Volunteers
- 107 people
- Sponsor
- Ottawa Heart Institute Research Corporation
Acute Myocardial Infarctus
Safety and Efficacy Study of TRO40303 for Reduction of Reperfusion Injury in Patients Undergoing Percutaneous Coronary Intervention for Acute Myocardial Infarction
Objectives of the phase 2 prospective, multicenter, randomized, double-blind, placebo-controlled study is to assess safety and efficacy of TRO40303 administered just before balloon inflation during percutaneous coronary…
- Trial name
- NCT01374321
- Testing
- TRO40303
- Where
- 11 sites in Denmark, France and 2 more
- Volunteers
- 168 people
- Sponsor
- Hoffmann-La Roche
ST Elevation Myocardial Infarction
Prasugrel vs. Ticagrelor on Myocardial Injury in STEMI
The investigators propose to perform a randomized clinical trial comparing prasugrel vs. ticagrelor in 60 patients with ST elevation acute myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention.
- Trial name
- COMPARE (NCT03435133)
- Testing
- Prasugrel, Ticagrelor
- Where
- Spain
- Volunteers
- 61 people
- Sponsor
- AORTICA Group
Serum Copper, Cardiac Enzymes
Correlation Between Serum Copper and Cardiac Enzymes in Acute Myocardial Infarction
This study aims to investigate the correlation between serum copper levels and cardiac enzymes in patients with acute myocardial infarction (AMI).
- Conditions
- Serum Copper, Cardiac Enzymes, Acute Myocardial Infarction
- Trial name
- NCT07076758
- Testing
- Transthoracic echocardiography
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Sohag University
Acute Myocardial Infarction (AMI), Percutaneous Coronary Intervention (PCI)
A Study on the Development and Application of a Cardiac Rehabilitation Nursing Intervention Protocol for Patients With First-Episode Acute Myocardial Infarction Following PCI, Based on a Socio-Ecological Theory Model
The purpose of this [Study Type: Clinical Trial] is to investigate whether a cardiac rehabilitation nursing intervention based on the socio-ecological model can improve rehabilitation-related outcomes in patients.
- Trial name
- NCT07753915
- Testing
- A Cardiac Rehabilitation Nursing Intervention Program Based on the Social-Ecological Theory Model
- Where
- China
- Volunteers
- 66 people
- Sponsor
- Jinzhou Medical University
Acute Coronary Syndrome, ST Segment Elevation Myocardial Infarction
MAGnesium-based Bioresorbable Scaffold in ST Segment Elevation Myocardial Infarction
This is a prospective, randomized, active control, single-blind, non-inferiority, multicenter clinical trial. 148 subjects will be registered at up to 10 Spanish sites. Subjects will be followed for 5 years.
- Conditions
- Acute Coronary Syndrome, ST Segment Elevation Myocardial Infarction, Stent
- Trial name
- MAGSTEMI (NCT03234348)
- Testing
- Percutaneous coronary intervention
- Where
- 11 sites in Spain
- Volunteers
- 151 people
- Sponsor
- Hospital Clinic of Barcelona
Acute Myocardial Infarction
The STREAM Percutaneous Coronary Intervention Anticoagulant Sub-study
The purpose of this study is to assess the safety and efficacy of Enoxaparin and Unfractionated Heparin in St Elevation Myocardial Infarction patients undergoing primary percutaneous coronary intervention.
- Trial name
- NCT00882635
- Testing
- enoxaparin, Unfractionated heparin
- Where
- 2 sites in Canada
- Volunteers
- 44 people
- Sponsor
- Robert Welsh
Acute Myocardial Infarction: Rehabilitation Phase
Autonomic and Metabolic Response to Cardiac Rehabilitation After Acute MI
Ischemic heart disease remains the leading cause of death in the western world. The beneficial effects of cardiac rehabilitation on the evolution of ischemic heart disease are known, but the effects of rehabilitation on the…
- Trial name
- RIABILITOMICA (NCT06298513)
- Testing
- Cardiac rehabilitation
- Where
- Italy
- Volunteers
- 25 people
- Sponsor
- Istituto Auxologico Italiano
Acute Myocardial Infarction
Application of Index of Microcirculatory Resistance to Evaluate Myocardial Protection After Ischemic Adaptation
To evaluate the protective effect of IPC on the myocardial microcirculation response through IMR and the predictive value of IMR on the degree of myocardial reperfusion and the prognosis of patients.
- Trial name
- NCT04952740
- Testing
- IPC+PCI, No IPC
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Peking University Third Hospital
Acute Coronary Syndrome, Depression
MBCT Delivered Via Group Videoconferencing for ACS Syndrome Patients With Depressive Symptoms
Brief Summary: The aim of this study is to explore the initial feasibility and acceptability of (a) Mindfulness-Based Cognitive Therapy (MBCT) adapted for ACS patients; (b) the group videoconferencing delivery medium; and (c)…
- Conditions
- Acute Coronary Syndrome, Depression, Myocardial Infarction, Unstable Angina
- Trial name
- NCT04231097
- Testing
- MBCT intervention for ACS patients
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Massachusetts General Hospital
Acute Coronary Syndrome, Myocardial Infarction
Myocardial Infarction With Non-obstructive Coronary Arteries in Turkish Population
The objective of this study is to analyze the Demographics, Clinical Profiles, Management, in-Hospital and Long-Term Outcomes of Patients with Acute Coronary Syndrome Syndrome And Myocardial Infarction with Non-obstructive…
- Conditions
- Acute Coronary Syndrome, Myocardial Infarction, Atrial Fibrillation, Diabetes Mellitus
- Trial name
- MINOCA-TR (NCT03364387)
- Where
- Turkey (Türkiye)
- Volunteers
- 16,026 people
- Sponsor
- Cardiovascular Academy Society, Turkey
Stroke, Cardiovascular
Cardiovascular Effects of Acute Exercise Post-Stroke
There is an urgent need to reduce the impact of stroke by promoting optimal rehabilitation strategies that decrease the risk of stroke.
- Trial name
- ACES (NCT03570216)
- Testing
- Cardiopulmonary exercise test, Moderate-intensity continuous exercise, High-intensity interval exercise
- Where
- Canada
- Volunteers
- 4 people
- Sponsor
- McMaster University
Coronary Artery Stent Thrombosis
Platelet Reactivity in Stent Thrombosis Patients
Recent studies have demonstrated a marked interindividual variability of clopidogrel's capacity to inhibit platelet aggregation with a substantial proportion (11-34%) of the patients considered non-responders to clopidogrel…
- Trial name
- MAPCAT (NCT01012544)
- Testing
- Clopidogrel
- Where
- Netherlands
- Volunteers
- 187 people
- Sponsor
- St. Antonius Hospital
STEMI
Randomized Trial of a Quality Improvement Intervention to Decrease D2B Time in Primary PCI for AMI
The primary objective of this study is to assess whether an aggressive quality improvement intervention strategy will decrease time from hospital presentation to first balloon inflation in non-transfer patients with acute ST…
- Trial name
- RAPID-PCI (NCT01625104)
- Testing
- Non Intervention, Agressive Intervention Process Improvement Strategies
- Where
- United States
- Volunteers
- 882 people
- Sponsor
- University of Michigan
STEMI
Cangrelor Following Ticagrelor Loading vs Ticagrelor Loading Alone in STEMI
Platelets and thrombus formation play a key role in the pathogenesis of acute coronary artery occlusion and subsequent myocardial infarction.
- Trial name
- NCT02943369
- Testing
- Ticagrelor 180 mg loading dose, Cangrelor 30 mcg/kg bolus + 4 mcg/kg/min
- Where
- Greece
- Volunteers
- 30 people
- Sponsor
- Attikon Hospital
Acute Myocardial Infarction
Safety and Efficacy of Intracoronary Adult Human Mesenchymal Stem Cells After Acute Myocardial Infarction
Early reperfusion strategies in tandem with remarkable advances in drugs and devices for treating myocardial infarction (MI) have contributed to a reduction in early mortality, but cardiovascular disease remains the leading cause…
- Trial name
- SEED-MSC (NCT01392105)
- Testing
- Mesenchymal stem cell, Control group
- Where
- 3 sites in South Korea
- Volunteers
- 80 people
- Sponsor
- Yonsei University
Acute Myocardial Infarction
Safety and Efficacy of Adipose Derived Regenerative Cells (ADRCs) Delivered Via the Intracoronary Route in the Treatment of Patients With ST-elevation Acute Myocardial Infarction (AMI)
Double blind, prospective, randomized, placebo-controlled Safety and Efficacy trial of ADRCs delivered via the intracoronary route in the treatment of patients with ST-elevation acute myocardial infarction (STEMI).
- Trial name
- ADVANCE (NCT01216995)
- Testing
- Dose A
- Where
- 4 sites in Netherlands, Poland
- Volunteers
- 23 people
- Sponsor
- Cytori Therapeutics
Mild Therapeutic Hypothermia, Cardiogenic Shock
Effect of Mild Therapeutic Hypothermia on the Doses of Vasopressors and Inotropes in Cardiogenic Shock Complicating Acute Myocardial Infarction
The study aimed to assess the effects of mild therapeutic hypothermia (MTH) on vasopressors and inotropes in patients with cardiogenic shock (CS) due to acute myocardial infarction (AMI).
- Conditions
- Mild Therapeutic Hypothermia, Cardiogenic Shock, Acute Myocardial Infarction, Vasopressors
- Trial name
- NCT06947616
- Testing
- Mild therapeutic hypothermia
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University