Clinical trials: Acute Myocardial Infarction, completed
Myocardial Infarction
MiSaver® Stem Cell Treatment for Heart Attack (Acute Myocardial Infarction)
The objective of the present study is to establish the safety and efficacy of MiSaver® Stem Cell Treatment After a Heart Attack (Acute Myocardial Infarction)
- Trial name
- MiSaver® (NCT04050163)
- Testing
- MiSaver®
- Where
- 2 sites in Taiwan
- Volunteers
- 11 people
- Sponsor
- Honya Medical Inc
Pulmonary Disease, Chronic Obstructive
An Observational Study of Beta-Blocker Use in Patients With COPD and Acute MI
The study is a prospective, observational study of patients admitted to the BLOCK COPD network hospitals with acute AMI and Chronic Obstructive Pulmonary Disease (COPD) to determine the prevalence of COPD in patients admitted to…
- Trial name
- BLOCK2 (NCT04717492)
- Testing
- Observational
- Where
- 24 sites in United States
- Volunteers
- 584 people
- Sponsor
- University of Minnesota
Acute Coronary Syndrome
FRANCIS-ACS Trial: A Study of the Safety and Efficacy of A 002 in Subjects With Acute Coronary Syndromes
The objective of this study is to evaluate the safety and efficacy of A 002 when added to high dose atorvastatin in subjects with an acute coronary syndrome (ACS)
- Trial name
- FRANCIS-ACS (NCT00743925)
- Testing
- Varespladib Methyl (A-002)
- Where
- 44 sites in Georgia, Russia and 1 more
- Volunteers
- 625 people
- Sponsor
- Anthera Pharmaceuticals
Diabetes, Hyperglycemia
Intensive Insulin Therapy in Non-diabetic Patients With Acute Myocardial Infarction and Hyperglycaemia
Hyperglycemia at admission has been associated with bad prognosis in patients with acute myocardial infarction (AMI). The clinical benefit of intensive treatment with insulin has been evaluated in diabetic patients admitted to…
- Conditions
- Diabetes, Hyperglycemia, Acute Myocardial Infarction
- Trial name
- INSUCOR (NCT00362778)
- Testing
- Insulin
- Volunteers
- 28 people
- Sponsor
- Hospital Clinic of Barcelona
Acute Myocardial Infarction
Tirofiban Intracoronary Bolus-only Versus Intravenous Bolus Plus Infusion in STEMI Patients
The aim of this randomized trial is to compare the efficacy of high dose tirofiban administered as either an intracoronary bolus alone or as an intravenous bolus followed by a maintenance infusion with respect to microvascular…
- Trial name
- NCT01109134
- Testing
- tirofiban intracoronary bolus-only, tirofiban intravenous bolus plus infusion
- Volunteers
- 49 people
- Sponsor
- Kosuyolu Heart Hospital
Acute Myocardial Infarction
To Evaluate the Efficacy and Safety of Hearticelgram®-AMI in Patients With Acute Myocardial Infarction.
Through the injection of Hearticellgram-AMI into acute myocardial infarction patients who are the primary targets of the drug, long term efficacy in the improvement of the left ventricle ejection fraction upon the first cell…
- Trial name
- NCT01652209
- Testing
- Hearticellgram-AMI
- Where
- 10 sites in South Korea
- Volunteers
- 90 people
- Sponsor
- Pharmicell Co., Ltd.
Myocardial Infarction, Reperfusion Injury
Safety and Effectiveness of Intra-coronary Nitrite in Acute Myocardial Infarction
Despite advances in the treatment of heart attacks the complications and death rates from failure of the heart to pump properly after treatment remain high.
- Conditions
- Myocardial Infarction, Reperfusion Injury, Myocardial Ischemia, Cardiovascular Diseases
- Trial name
- NITRITE-AMI (NCT01584453)
- Testing
- Sodium Nitrite
- Where
- United Kingdom
- Volunteers
- 80 people
- Sponsor
- Barts & The London NHS Trust
Heart Attack, Cardioplegia Solution Adverse Reaction
Combined Use of a Novel Cardioplegic Formula With MPS® Versus Cardioplexol ® in Urgent Isolated CABG Using MiECC in Patients With Recent Acute Myocardial Infarction
The goal of this study is to compare the two cardioplegia solutions (blood cardioplegia by means of MPS ® vs. Cardioplexol ®) regarding perioperative outcome and with special attention to cardiac markers in patients with a recent…
- Conditions
- Heart Attack, Cardioplegia Solution Adverse Reaction, Coronary Artery Bypass Grafting (CABG)
- Trial name
- NCT04309994
- Testing
- Myocardial protection system (MPS), Cardioplexol
- Where
- Switzerland
- Volunteers
- 307 people
- Sponsor
- University Hospital, Basel, Switzerland
Acute Myocardial Infarction
Study for Evaluation of Newly Onset Chest Pain and Rapid Diagnosis of Myocardial Necrosis
This is a national multi-center, prospective surveillance study in patients with suspected acute coronary syndrome. Eligible patients must present to one of the participating Emergency Departments within 24 hours from the time of…
- Trial name
- stenoCARDIA (NCT03227159)
- Volunteers
- 1,818 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Acute Myocardial Infarction
Safety and Efficacy Study of Thymosin Beta 4 in Patients With Acute Myocardial Infarction.Infarction
A multicenter randomized double-blind placebo parallel control design was used in this study.60 subjects eligible for inclusion will be randomly assigned to either a low-dose (0.25ug/kg) medium-dose (0.5ug/kg) high-dose…
- Trial name
- NCT05485818
- Testing
- Low Dose, Middle Dose, High Dose
- Where
- China
- Volunteers
- 62 people
- Sponsor
- Beijing Northland Biotech. Co., Ltd.
Myocardial Infarction, Unstable Angina
The Impact of Gratitude on Biology and Behavior in Persons With Heart Disease
Overall, the investigators aim to recruit 150 subjects during their hospitalization for an acute coronary syndrome (ACS). At two weeks post-ACS, the investigators will assess levels of gratitude and optimism, draw blood for…
- Trial name
- GRACE (NCT01709669)
- Where
- United States
- Volunteers
- 212 people
- Sponsor
- Massachusetts General Hospital
Gender Differences, Adherence, Medication
Gender Differences in Prevention Strategies and Therapeutic Adherence After Acute Myocardial Infarction
PARTICIPANT CENTERS: 25 hospitals managing routinely acute myocardial infarction (AMI) and representing different regions from Spain will be invited to participate.
- Conditions
- Gender Differences, Adherence, Medication, Therapeutic Adherence, Type 1 Acute Myocardial Infarction
- Trial name
- GENAMI (NCT05619601)
- Where
- 25 sites in Spain
- Volunteers
- 530 people
- Sponsor
- Spanish Society of Cardiology
Acute ST Segment Elevation Myocardial Infarction
Platelet Function in Resuscitated Patients
Approx. 65% of resuscitated patients at the intensive care unit for internal medicine are due to myocardial infarction. Almost all patients are initially diagnosed and treated in the cath lab.
- Trial name
- NCT02914795
- Testing
- diagnostic analysis of platelet function
- Where
- Austria
- Volunteers
- 99 people
- Sponsor
- Medical University of Graz
Acute Kidney Injury, Cardiogenic Shock
Acute Kidney Injury in Adult Patients Supported by VA-ECMO
Post-cardiotomy cardiogenic shock (PCCS) occurs in 2-6% of patients undergoing cardiac surgery, and 1% of cardiac surgery patients will require mechanical circulatory support using Veno-Arterial ExtraCorporeal Membrane…
- Trial name
- AKI-ECMO (NCT04082312)
- Testing
- No intervention
- Where
- France
- Volunteers
- 347 people
- Sponsor
- Groupe Hospitalier Pitie-Salpetriere
Acute Myocardial Infarction
Noninvasive Ventilation in Acute Myocardial Infarction
Cardiovascular diseases, especially acute myocardial infarction (AMI), represent the major cause of mortality and morbidity in the world.
- Trial name
- NCT01484795
- Testing
- BILEVEL (Respironics), Continuos positive airway pressure (Respironics)
- Volunteers
- 10 people
- Sponsor
- Centro Universitário Augusto Motta
Chest Pain, Coronary Artery Disease
ARgentinean Risk Assessment Registry in ACS; the ARRA-RACS Study
The first aim of this trial is to assess the long-term prognostic value of Omega-3 index, which is a measure of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) relative to other fatty acids in the erythrocyte membrane…
- Conditions
- Chest Pain, Coronary Artery Disease, Unstable Angina Pectoris, Myocardial Infarction
- Trial name
- ARRA-RACS (NCT01377402)
- Where
- 10 sites in Argentina, Norway
- Volunteers
- 982 people
- Sponsor
- Helse Stavanger HF
STEMI - ST Elevation Myocardial Infarction
A Randomized Comparison of Long-Term Healing Between Biodegradable- Versus Durable-Polymer Everolimus Eluting Stents in STEMI
This study aims to compare the acute thrombogenecity and frequency of neoatherosclerotic lesions and other aspects of long term arterial healing such as the frequency of malapposed and uncovered stent struts at 3 years among…
- Trial name
- CONNECT (NCT03440801)
- Testing
- Synergy, Xience
- Where
- Japan
- Volunteers
- 240 people
- Sponsor
- Tokorozawa Heart Center
Microbial Colonization, Coronary Artery Disease
Effect of Acute Cardiovascular Disease on Microbiome
Atherosclerotic diseases such as coronary artery disease (CAD) and peripheral arterial disease (PAD) are the leading cause of morbidity and mortality in the industrialized world.
- Conditions
- Microbial Colonization, Coronary Artery Disease, Myocardial Infarction, Acute Coronary Syndrome
- Trial name
- MIAMI (NCT05456802)
- Testing
- Standard of care treatment
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- University Hospital, Essen
Periodontitis
Treatment of Periodontal Disease in Patients With Acute Myocardial Infarction
The main objective of this study is to evaluate the effect of treatment periodontal endothelium-dependent artery of the arm in patients with acute myocardial infarction with ST-segment elevation undergoing primary coronary…
- Trial name
- TPAMI (NCT02543502)
- Testing
- periodontal treatment
- Where
- Brazil
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Instituto de Cardiologia do Rio Grande do Sul
Fragility
Intervention in Frailty Versus Usual Care in Frail Patients After an Acute Myocardial Infarction
Frailty has been associated to a worse outcome in acute coronary syndromes, but the best management of frail patients after an acute coronary syndrome remains unknown.
- Trial name
- FRAMIP (NCT02715453)
- Testing
- Intervention on frailty
- Where
- Spain
- Volunteers
- 150 people
- Sponsor
- University of Valencia