Clinical trials: Acute Pain, completed
Cardiac Surgery
Efficacy of Ultrasound Guided PIFB Versus Lidocaine Infusion on Postoperative Pain After Sternotomy
Chronic pain is a common complication after cardiothoracic surgery. The prevalence of post-sternoyomy pain syndrome (PSPS) ranges from 33% to 91%.
- Trial name
- NCT05885230
- Testing
- pecto intercostal fascial block using bupivacaine 0.25%, lidocaine infusion
- Where
- Egypt
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University
Pain, Acute
PENTHROX™ in the Canadian Emergency Department (ED)
This Canadian, multi-centre, prospective, real world study is designed to evaluate the effectiveness of low dose methoxyflurane (MEOF) (PENTHROX™) for the treatment of moderate to severe pain associated with trauma in the…
- Trial name
- ADVANCE-ED (NCT03868436)
- Testing
- Methoxyflurane 3mL
- Where
- 6 sites in Canada
- Volunteers
- 99 people
- Sponsor
- Purdue Pharma, Canada
Acute Dental Pain
Evaluation of the Analgesic Efficacy of the Combination of Dexketoprofen + Paracetamol and the Combination of Naproxen Sodium + Codeine in Patients With Acute Dental Pain
Acute dental pain is one of the most challenging conditions to treat and manage in dental practice. The aim of this study was to compare the efficacy of naproxen sodium + codeine phosphate (550/30 mg) and dexketoprofen trometamol…
- Trial name
- NCT06916234
- Testing
- Dexketoprofen Trometamol + Paracetamol, Naproxen Sodium + Codeine Phosphate
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- ibrahim doğru
Acute Pain
Paravertebral Catheters for Pancreatic Surgery
Design: Level I randomized prospective outcomes study comparing two groups of patients. One group will receive bupivacaine and dilaudid thoracic epidural analgesia (PCA) post-operatively.
- Trial name
- NCT02363777
- Testing
- Epidural, Paravertebral catheters
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Minnesota
Pain, Postoperative, Pain
The Adolescent Surgery Experience: A Mixed Methods Analysis
New chronic pain and opioid use are reported as prevalent among adolescents undergoing major surgery; many unanswered questions remain regarding recovery and the anticipated pain trajectory across procedures and the interaction…
- Conditions
- Pain, Postoperative, Pain, Pain, Acute, Pain, Chronic
- Trial name
- NCT05482919
- Testing
- Baseline Survey, Post Operative Surveys, Qualitative Interviews
- Where
- United States
- Volunteers
- 501 people
- Sponsor
- Children's Hospital of Philadelphia
Adolescent Behavior, Pain, Acute
The Effect of Stress Ball and Breathing Exercises on Reducing Fear and Pain Associated with PCR Testing
The COVID-19 pandemic continues to be one of the longest lasting pandemics experienced in recent times. Although the disease shows symptoms in different ways, the most effective diagnostic method known is the PCR test.
- Trial name
- NCT05250544
- Testing
- control group
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- Karamanoğlu Mehmetbey University
Analgesia, Nerve Blocks
Evaluation of Adjuvant Use in Selective Trunk Block
"Evaluation of the Anesthetic and Analgesic Efficacy of Dexamethasone in Selective Trunk Blocks
- Conditions
- Analgesia, Nerve Blocks, Postoperative Pain, Acute
- Trial name
- NCT06540534
- Testing
- Dexamethasone, kontrol group
- Where
- Turkey (Türkiye)
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Acute Pain
IV Acetaminophen as Adjuvant Analgesic to Hydromorphone - Emergency Department Patients
The goal of this randomized clinical trial is to compare the analgesic efficacy and side effect profile of IV acetaminophen as an analgesic adjunctive medication to IV hydromorphone for the treatment of acute pain experienced by…
- Trial name
- NCT03553498
- Testing
- IV acetaminophen, hydromorphone
- Where
- United States
- Volunteers
- 162 people
- Sponsor
- Albert Einstein College of Medicine
Unstable Angina
MMP Polymorphisms and Acute Coronary Syndromes
Some Matrix Metalloproteases, proteases degrading the extracellular matrix, play a relevant role in structure and stability of atherosclerotic plaques.
- Trial name
- NCT00484406
- Where
- 2 sites in Italy
- Sponsor
- University of Trieste
Anesthesia, Analgesia
Anterior Quadratus Lumborum Block Versus Erector Spina Plane Block in Percutaneous Nephrolithotomy Surgery
In this study, it was aimed to evaluate the effects of anterior quadratus lumborum block (QLB3) and Erector Spina Plane Block (ESPB) on postoperative acute pain scores and opioid consumption in the first 24 hours in Percutaneous…
- Conditions
- Anesthesia, Analgesia, Patient Controlled Analgesia, Quadratus Lumborum Block
- Trial name
- NCT05822492
- Testing
- Group QLB3, Group ESPB, Group Control
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Ondokuz Mayıs University
Covid19
Efficacy of Adaptogens in Patients With Long COVID-19
The aim of this clinical trial of a fixed combination of standardized extracts from Rhodiola rosea roots, Schisandra chinensis berry and Eleutherococcus senticosus root (ADAPT-232) in COVID-19 patients is to demonstrate possible…
- Trial name
- NCT04795557
- Testing
- ADAPT-232 oral solution
- Where
- Georgia
- Volunteers
- 100 people
- Sponsor
- Swedish Herbal Institute AB
Migraine Disorders, Migraine
Treximet (Sumatriptan/Naproxen Sodium), Formerly Known as Trexima, In The Acute Treatment Of Multiple Migraine Attacks
The purpose of this study is to determine the consistency of response for Treximet (sumatriptan/naproxen sodium), formerly known as Trexima, when treating four acute migraine attacks at the mild pain phase and within 1 hour of…
- Trial name
- NCT00240630
- Testing
- sumatriptan succinate/naproxen sodium
- Where
- 50 sites in United States
- Volunteers
- 646 people
- Sponsor
- GlaxoSmithKline
Acute Coronary Syndrome
Fondaparinux Trial With Unfractionated Heparin (UFH) During Revascularization in Acute Coronary Syndromes (ACS)
The purpose of this study is to compare the safety of two different dose regimens of unfractionated heparin (UFH) during a percutaneous coronary intervention (PCI) procedure in patients with UA (unstable angina)/NSTEMI (non ST…
- Trial name
- FUTURA/OASIS 8 (NCT00790907)
- Testing
- fondaparinux background and standard dose UFH, Fondaparinux background and low dose heparin, Open label fondaparinux
- Where
- 203 sites in United States, Argentina and 16 more
- Volunteers
- 3,235 people
- Sponsor
- GlaxoSmithKline
Hip Fractures, Acute Post Operative Pain
PENG vs SIFI Block for Positioning Pain During Spinal Anesthesia
This study aims to compare the effectiveness of preoperative ultrasound-guided suprainguinal fascia iliaca compartment block (SFICB) and pericapsular nerve group block (PENG) in preventing positioning pain during spinal…
- Conditions
- Hip Fractures, Acute Post Operative Pain, Nerve Block, Spinal Anesthesia
- Trial name
- NCT05549011
- Testing
- PENG Block, SIFI compartment block, Numeric Rating Scale
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Low Back Pain
Efficacy of Motor Control and Diathermy Treatment in Acute Low Back Pain
Lumbar pain is considered one of the most frequent health problems faced by human populations on a global scale. This study will be carried out to evaluate the efficiency of motor control treatments combined with diathermy in…
- Trial name
- NCT03386084
- Testing
- microwave diathermy
- Where
- Spain
- Volunteers
- 22 people
- Sponsor
- University of Alcala
Acute Pain
Efficacy of Intravenous (IV) Paracetamol for Treatment of Acute Pain
The purpose of this study is to determine whether Iv paracetamol is as effective as Iv Morphine sulfate on control of the acute pain in Patient with limb trauma.
- Trial name
- NCT01465984
- Testing
- Paracetamol
- Where
- Iran
- Volunteers
- 60 people
- Sponsor
- Tehran University of Medical Sciences
Neck Pain Musculoskeletal, Work Related Musculoskeletal Disorders
Effects of Aerobic and Combined Exercise on Pain and Fatigue in Workers With Chronic Neck Pain
This randomized controlled trial investigated the acute effects of aerobic exercise (AE) and combined aerobic and cervical-upper extremity resistance exercise (CE) on the pressure pain threshold (PPT), pain perception, and…
- Trial name
- EIH-CNNP (NCT07546838)
- Testing
- Aerobic Exercise, Combined Exercise, Informed Control
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people
- Sponsor
- Hacettepe University
Acute Low Back Pain
Nonivamide/Nicoboxil Ointment in Acute Low Back Pain
The aim of this study is to assess the efficacy and tolerability of Nicoboxil/Nonivamide ointment in comparison to Nicoboxil, Nonivamide, and placebo ointments for the treatment of acute low back pain.
- Trial name
- NCT01708915
- Testing
- nicoboxil, nonivamide + nicoboxil (Finalgon), nonivamide
- Where
- 37 sites in Germany
- Volunteers
- 805 people
- Sponsor
- Boehringer Ingelheim
Prematurity, Pain Acute
Pain and Comfort Level During Orogastric Catheter Insertion in Preterms
Purpose of the research: This research was planned to evaluate the effect of breast milk and dextrose application, which are pain relief methods, on the pain and comfort levels of preterm babies who will have an orogastric tube…
- Conditions
- Prematurity, Pain Acute, Comfort, Orogastric Tube Insertion
- Trial name
- OGpreterm (NCT06222047)
- Testing
- breast milk, dextrose
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Dokuz Eylul University
Acute Neck Pain
The Effectiveness and Cost-effectiveness of Motion Style Acupuncture Treatment (MSAT) for Acute Neck Pain: A Multi-center Randomized Controlled Trial
The investigators will evaluate the comparative effectiveness and safety of Motion Style Acupuncture Treatment (MSAT) therapy for acute neck pain compared to acupuncture.
- Trial name
- NCT04539184
- Testing
- Motion Style Acupuncture Treatment (MSAT), Acupuncture
- Where
- 4 sites in South Korea
- Volunteers
- 128 people
- Sponsor
- Jaseng Medical Foundation
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