Clinical trials: Acute Pain, completed
Acute Gouty Arthritis
Efficacy and Safety of Lumiracoxib 400 mg Once Daily in Acute Flares of Gout
This study is designed to develop our understanding of the efficacy and safety of using lumiracoxib in the treatment of patients with acute gout.
- Trial name
- NCT00170781
- Testing
- Lumiracoxib
- Where
- 2 sites in Germany, Switzerland
- Volunteers
- 234 people
- Sponsor
- Novartis
Post-operative Pain
Electronic Visual Analogue Scale in Acute Postoperative Pain
When assessing acute post-operative pain, the validity, reproducibility and reliability of Visual Analogue Scale (VAS) and verbal Numerical Rating Scale (NRS) have been investigated extensively.
- Trial name
- NCT01878903
- Testing
- Electronic VAS
- Where
- China
- Volunteers
- 92 people
- Sponsor
- Cheung Chi Wai
Pain, Chronic, Pain, Acute
Real-World Experience of Athletes Treated With SAM
Low-intensity continuous ultrasound (LICUS) is an FDA-approved bio regenerative technology, applied with a wearable device (SAM, Zetroz Systems LLC) for daily use.
- Conditions
- Pain, Chronic, Pain, Acute, Sport Injury, Soft Tissue Injuries
- Trial name
- NCT04177537
- Testing
- Low Intensity Continuous Ultrasound
- Volunteers
- 15 people
- Sponsor
- ZetrOZ, Inc.
Acute Appendicitis, Abdominal Pain
Diagnostic Performance of Serum Calprotectin in Acute Appendicitis
This prospective observational study evaluated the diagnostic performance of serum calprotectin in patients presenting with acute abdominal pain and suspected acute appendicitis.
- Trial name
- SCP-AA (NCT07643142)
- Testing
- Serum Calprotectin Measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Breast Cancer Surgery, Postoperative Pain, Acute
Chronic Pain in Post-Mastectomy Patients; The Difference Between Pectoral Nerve (PECS I-II) and Erector Spinal Plane (ESP) Blocks
This study looks at two types of injections (called PECS and ESP blocks) to see which one works better for reducing pain after breast cancer surgery (mastectomy).
- Conditions
- Breast Cancer Surgery, Postoperative Pain, Acute, Postoperative Pain, Chronic, Post-mastectomy Pain Syndrome
- Trial name
- NCT06900842
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Hacettepe University
Chronic Pain, Anaesthesia
Comprehensive Pain Programme to Determine Mechanism of Transition of Acute to Chronic Postsurgical Pain
To determine whether central sensitization is a mechanism of CPSP (chronic postsurgical pain) in women who will develop CPSP compared to women with no CPSP after hysterectomy.
- Conditions
- Chronic Pain, Anaesthesia, Genetics Predisposition
- Trial name
- TAHP (NCT02025153)
- Testing
- pain testing
- Where
- Singapore
- Volunteers
- 216 people
- Sponsor
- KK Women's and Children's Hospital
Duloxetine, Magnesium Sulphate
Pain Relieving Potentials of Combination of Oral Duloxetine and Intravenous Magnesium Sulphate in Post Mastectomy Pain
This study aims to evaluate the effect of combined duloxetine and IV Magnesium sulphate to decrease acute and chronic post mastectomy pain.
- Conditions
- Duloxetine, Magnesium Sulphate, Post-mastectomy Pain Syndrome
- Trial name
- NCT06087211
- Testing
- Magnesium sulphate and Duloxetine, Duloxetine
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- National Cancer Institute, Egypt
Hip Fracture
Fascia Iliaca Compartment Blockade as Analgesia for Hip Fractures in the Acute Phase
To evaluate the analgesic potential of an neural blockade (Fascia iliaca compartment) with local anaesthetics in patients with hip fracture immediately after arrival in the emergency department.
- Trial name
- NCT00162630
- Testing
- Fascia Iliaca Compartment Blockade
- Where
- Denmark
- Volunteers
- 48 people
- Sponsor
- Hvidovre University Hospital
Analgesia After ED Discharge for Extremity Injuries
Comparing the Efficacy of Oral Opioids for Outpatient Acute Pain Management After ED Discharge Discharge
There will be 3 randomized, double-blinded clinical trials to help determine which of commonly prescribed oral opioid combination is most effective in managing acute extremity pain after discharge from the adult emergency…
- Trial name
- NCT01402375
- Testing
- Hydrocodone (first trial), Codeine (first trial), Oxycodone (for second trial)
- Where
- United States
- Volunteers
- 720 people
- Sponsor
- Montefiore Medical Center
Sickle Cell Crisis, Acute Pain
Low-dose Ketamine vs Morphine for Vaso-occlusive Crisis in Sicklers
This clinical trial will inform of the role of Low dose ketamine in the acute treatment of severe painful sickle cell crisis in children in a day-case sickle cell centre.
- Trial name
- KEM-VOC (NCT02434939)
- Testing
- Low dose ketamine, Morphine
- Where
- Uganda
- Volunteers
- 240 people
- Sponsor
- Makerere University
Postoperative Pain
Comparison of the Efficacy and Safety of Q8003 Versus Its Individual Components in Bunionectomy Patients
This is a randomized, double-blind, multicenter, fixed dose factorial study of Q8003 12 mg/8 mg and Q8003 6 mg/4 mg versus its individual morphine sulfate and oxycodone hydrochloride components for the management of acute…
- Trial name
- NCT00831051
- Testing
- Q8003, Morphine sulfate, Oxycodone HCl
- Where
- 6 sites in United States
- Volunteers
- 197 people
- Sponsor
- QRxPharma Inc.
Opioid; Intoxication, Perception Disturbance (Acute), Acute Pain
Pupillary Unrest in Ambient Light, and Relationship to Opioid-Induced Respiratory Depression
Volunteers will receive a weight-based opioid (remifentanil) infusion for 10 minutes. In the first run, serial pupillary measurements (pupillary unrest, pupil diameter) will be taken at baseline, and at 2.5-minute intervals…
- Conditions
- Opioid; Intoxication, Perception Disturbance (Acute), Acute Pain, Overdose of Opiate, Respiratory Depression
- Trial name
- NCT04301895
- Testing
- Continuous conversational interaction, Remifentanil infusion
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Musculoskeletal Pain
Altering The Transition From Acute to Chronic Pain (ATTAC-Pain)
The current way that pain is treated after trauma and injury is problematic. Most often pain after trauma is treated with opioids (ex. Percocet® or Vicodin®) or anti-inflammatories (ex. ibuprofen).
- Trial name
- ATTAC-PAIN (NCT03315533)
- Testing
- Duloxetine 30 milligrams (MG), Duloxetine 60 milligrams (MG)
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- Rhode Island Hospital
Low Back Pain
Acupuncture Using Yamamoto's Method for the Treatment of Acute Nonspecific Low Back Pain
The aim of the present study is to assess the effectiveness of acupuncture using Yamamoto's method for the treatment of ANLBP using the following outcomes:pain,functional capacity,quality of life and number of 50 mg sodium…
- Trial name
- ANLBP (NCT01124955)
- Testing
- Acupuncture, Non-penetrating acupuncture
- Where
- 2 sites in Brazil
- Volunteers
- 80 people
- Sponsor
- Federal University of São Paulo
Chest Pain
Copeptin Testing During Pre-hospital Care in the Treatment of Chest Pain Suggestive of Acute Coronary Syndrome
The main objective of our study is to evaluate the diagnostic value of copeptin testing in association with troponin HS testing during pre-hospital care (ambulance care) in the treatment of patients whose pattern of use is the…
- Trial name
- SCA COP (NCT02116426)
- Testing
- Blood work in the ambulance, Blood work upon arrival in the emergency room, Blood work at 3 hours post-arrival in the emergency room
- Where
- 2 sites in France
- Volunteers
- 320 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Pain
A Single-arm Study to Evaluate Safety and Effectiveness of VX-548 for Acute Pain
The purpose of this study is to evaluate the safety and effectiveness of VX-548 in treating acute pain.
- Trial name
- NCT05661734
- Testing
- Suzetrigine
- Where
- 14 sites in United States
- Volunteers
- 258 people
- Sponsor
- Vertex Pharmaceuticals Incorporated
Pain, Postoperative, Spine Injuries and Disorders
An Analysis of the Efficacy of a Pre-Emptive Multimodal Pain Regimen in Reducing Acute Post-Operative Pain and Narcotic Pain Medication Requirements in Spine Surgery
The aim of this study is to investigate the hypothesis that multimodal pain regimen (consisting of acetaminophen, celecoxib, gabapentin, and oxycodone) administered pre-operatively before elective spine surgery significantly…
- Conditions
- Pain, Postoperative, Spine Injuries and Disorders, Narcotic Use
- Trial name
- NCT04522206
- Testing
- Pre-op Multimodal analgesia (MMA) regimen + standard post-op oxycodone
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- NYU Langone Health
Cholecystitis, Cholecystitis, Acute
M-Tapa Block vs External Oblique Intercostal Block for Laparoscopic Cholesistectomy
Ultrasound (US)-guided Modified Perichondral Approach Thoracoabdominal Nerve (M-TAPA) block is a novel block that provides effective analgesia in the anterior and lateral abdominal walls after laparoscopic surgery, and local…
- Trial name
- NCT05502159
- Testing
- M-TAPA, EOB
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Medipol University
Coronary Angiography, Chest Pain
Coronary Computed Tomography for Systematic Triage of Acute Chest Pain Patients to Treatment (CT-STAT)
This is a prospective, randomized multicenter trial comparing MSCT to standard of care (SOC) diagnostic treatment in the triage of Emergency Department (ED) low to intermediate risk chest pain patients.
- Trial name
- CTSTAT (NCT00468325)
- Testing
- Multi-slice computed tomography, Rest-stress Nuclear Myocardial Perfusion Imaging
- Where
- 16 sites in United States
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- Corewell Health East
Chronic Postoperative Pain
Transition From Acute to Chronic Pain After Inguinal Hernia, Hysterectomy and Thoracotomy: Analysis of Risk Factors and Association With Genetic Polymorphisms
The treatment of postoperative pain continues to be inadequate in the investigators practice setting. Inadequate pain treatment not only contributes to postoperative complications in the short term but can also be a factor that…
- Trial name
- NCT01510496
- Testing
- Inguinal herniorraphy., Hysterectomy., Thoracotomy .
- Where
- 26 sites in Spain
- Volunteers
- 3,979 people
- Sponsor
- Fundacion IMIM
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.