Clinical trials: Acute Pain, completed
Chest Pain, ST Elevation Myocardial Infarction
The Accuracy of the Mini RELF Device for the Diagnosis of an Acute Coronary Artery Occlusion.
Patient delay in seeking medical attendance for symptoms of acute ST elevation myocardial infarction (STEMI) is the major obstacle to reduce the current mortality from acute coronary syndromes.
- Trial name
- RELF IIa (NCT02983396)
- Testing
- Diagnostic accuracy of Mini Relf Device
- Where
- 3 sites in Belgium
- Volunteers
- 64 people
- Sponsor
- University Ghent
Nerve Block, Nephrectomy, Analgesia
QLB Versus PVB for Acute Pain and Quality of Recovery After Laparoscopic Partial Nephrectomy
This trial is a prospective, randomized, single-center, open-label, parallel-arm, blinded-analysis trial, the objective of which is to evaluate the effect of transmuscular quadratus lumborum block (TMQLB) in the pain relief and…
- Trial name
- NCT03975296
- Testing
- preoperative single-shot TMQLB, preoperative single-shot TPVB, patient controlled intravenous analgesia(PCIA)
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Cui Xulei
Moderate to Severe Acute Pain
A Study to Evaluate the Efficacy and Safety of HR18042 Tablets in the Treatment of Postoperative Pain of Impacted Tooth.
The purpose of this study was to evaluate the Efficacy and safety of HR18042 tablets for the Treatment of Post-surgical Pain After extraction of impacted tooth, find the optimal dose.
- Trial name
- NCT04812860
- Testing
- HR18042, Tramadol hydrochloride ER
- Where
- China
- Volunteers
- 187 people
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Chest Pain
Chest Pain Triage at ED
CECIDOC is a prospective, monocentric and observational study comparing the diagnostic performance of ECG-base triage to a combination of ECG and cardiovascular risk factors for chest pain triage at ED.
- Trial name
- CECIDOC (NCT03913767)
- Where
- Belgium
- Volunteers
- 500 people
- Sponsor
- Université Catholique de Louvain
Migraine
Efficacy and Tolerability of Rimegepant for the Acute Treatment of Migraine in Adults Unsuitable for Triptan Use
This study is being conducted to evaluate the efficacy and tolerability of rimegepant in a population of adults that are unsuitable for triptan medications due to a previous intolerance, lack of efficacy, or contraindication…
- Trial name
- NCT05509400
- Testing
- Rimegepant
- Where
- 93 sites in United States, Australia and 13 more
- Volunteers
- 813 people
- Sponsor
- Pfizer
Pain Management
IBUPAP Study for Pain Management in Children
Current literature supports ibuprofen and APAP are the most commonly used analgesics in the pediatric ED for acute traumatic/non-traumatic pain.
- Trial name
- NCT03088800
- Testing
- Ibuprofen, APAP
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Antonios Likourezos
Acute Pre and Post Operative Pain
Acute Pain Assessment Using Facial Expression Analysis
Managing pain, which affects 20-50% of the population, is a major issue in daily clinical practice. Evaluation of pain intensity is essential to adapt treatment but as it mainly relies on self-report, this assessment is difficult…
- Trial name
- DEF-I (NCT03957967)
- Testing
- video taken
- Where
- France
- Volunteers
- 1,000 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Low Back Pain, Mechanical, Ibuprofen
"Management of Low Back Pain in the Emergency Department With Different Analgesic Dosages"
The Management of Low Back Pain in the Emergency Department Worldwide, low back pain is one of the most prevalent musculoskeletal disorders, and it constitutes one of the primary complaints in emergency departments.
- Conditions
- Low Back Pain, Mechanical, Ibuprofen, Analgesia, Pain Management
- Trial name
- NCT06064175
- Testing
- Ibuprofen 400 mg, Ibuprofen 800 mg
- Where
- Turkey (Türkiye)
- Volunteers
- 144 people
- Sponsor
- Ankara City Hospital Bilkent
Pain Acute, Acupuncture
Acupuncture for Pain Management During Uterine Aspiration
The proposed study will be a randomized, double blinded, placebo-controlled trial to evaluate the efficacy of auricular acupuncture as adjunct for pain management during abortion.
- Trial name
- NCT03391986
- Testing
- SEIRIN® Pyonex™ Acupuncture Needles, 12 mm Plasters
- Where
- United States
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- Columbia University
Acute Coronary Syndrome, Angina Pectoris, Unstable
Incremental Value of Point of Care H-FABP Testing in Primary Care Patients Suspected of Acute Coronary Syndrome
Rationale: Thoracic complaints, possibly due to a cardiac ischemic cause are a diagnostic challenge in general practice. When an underlying ischemic cardiac condition (AMI (acute myocardial infarction), UAP (unstable angina…
- Conditions
- Acute Coronary Syndrome, Angina Pectoris, Unstable, Angina Pectoris, Stable, Thoracic Diseases
- Trial name
- RAPIDA (NCT01826994)
- Testing
- heart type fatty acid binding protein testing
- Where
- 7 sites in Belgium, Netherlands
- Volunteers
- 303 people
- Sponsor
- Maastricht University Medical Center
Effectiveness of Aromatherapy
Aromatherapy for Management of Pain, Anxiety, and Nausea in the Acute Care Setting
The purpose of this interventional study is to investigate the effects of aromatherapy on an acute care unit and whether it is effective in decreasing physical or emotional stressors that occur as a hospitalized patient.
- Trial name
- NCT06400979
- Testing
- Elequil aromatab
- Where
- United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Postoperative Pain, Acute
The Effect of Local Anesthesia on Postopanalgesia in Patients Using Head Holder
Aim:The head holder used in neurosurgery operations causes pain in patients both peroperatively and postoperatively.Severe pain-related hemodynamic changes are seen in these participants.In our study, the investigators compared…
- Trial name
- NCT07629713
- Testing
- lidocaine was administered subcutaneously at 0.5% concentration., lidocaine was administered subcutaneously at 1% concentration.
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Kocaeli University
Acute Coronary Syndrome
Comparison of MEOPA + Paracetamol Versus Morphine Treatment in Acute Coronary Syndrome Analgesia.
In the management of acute coronary syndromes with ST-segment elevation (STEMI), early analgesia reduces the effects of hyperadrenalism which increases the size of myocardial infarction.
- Trial name
- SCADOLII (NCT02198378)
- Testing
- MEOPA and paracetamol, Morphine
- Where
- 40 sites in France, Reunion
- Volunteers
- 680 people
- Sponsor
- University Hospital, Toulouse
Acute Coronary Disease, Angina Unstable
Clopidogrel Optimal Loading Dose Usage to Reduce Recurrent EveNTs/Optimal Antiplatelet Strategy for InterventionS
The purpose of this study is to evaluate whether a higher dosage of clopidogrel with aspirin (two doses) will decrease the risk of ischemic complications (cardiac death (CV death), myocardial infarction (MI), stroke) after a…
- Trial name
- CURRENT/OASIS7 (NCT00335452)
- Testing
- Clopidogrel, acetylsalicyclic acid (ASA)
- Where
- 38 sites in United States, Argentina and 36 more
- Volunteers
- 25,086 people
- Sponsor
- Sanofi
Low Back Pain
A Comparison of Two Different Methods of Physical Therapy to Treat Acute and Subacute Low Back Pain
Recent research has shown that classifying patients with low back pain into treatment subgroups results in better improvements than treating all patients with low back pain the same.
- Trial name
- NCT02060617
- Testing
- Patient Education, Manual therapy of the thoracolumbosacral spine and hips, Motor control exercises
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Hendricks Regional Health
Acute Pain
Efficacy of Gabapentin vs. Placebo for Adjuvant Pain Control Following Acute Rib Fractures
A Multi-center, Randomized Controlled Trial of the Efficacy of Gabapentin vs. Placebo for Adjutant Pain Control Following Acute Rib Fractures.
- Trial name
- NCT02856750
- Testing
- Gabapentin
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Denver Health and Hospital Authority
Migraine
Efficacy and Safety Study of Rimegepant for the Acute Treatment of Migraine in Japanese Subjects (Japan Only)
This study is being conducted to determine the appropriate dose of rimegepant in Japanese subjects, as well as to evaluate the efficacy, safety, and tolerability of rimegepant in Japanese subjects for the acute treatment of…
- Trial name
- NCT05399459
- Testing
- Rimegepant 25 MG, Rimegepant 75 MG
- Where
- 50 sites in Japan
- Volunteers
- 897 people
- Sponsor
- Pfizer
Acute Low Back Pain
An Educational and Exercise Program as Secondary Prevention of Recurrent Lower Back Pain in Healthcare Workers
At Lyon University Medical Center, back problems are the leading cause of sick leave. The course of lower back pain is usually relatively short (recovery occurs within 4 to 6 weeks in 90% of cases).
- Trial name
- PRESLO (NCT00782925)
- Testing
- educational program, exercise program, Self-led exercises
- Where
- France
- Volunteers
- 351 people
- Sponsor
- Hospices Civils de Lyon
Acute Pain
Acupuncture for Acute and Chronic Pain in Air Force Personnel
The purpose of this project is to conduct a scientifically rigorous investigation of the clinical outcomes, quality of life, and cost associated with the delivery of acupuncture in the treatment of acute and chronic pain in…
- Trial name
- NCT00286390
- Testing
- Acupuncture
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Samueli Institute for Information Biology
Opioid Use, Unspecified
Investigating Interventions to Reduce Residual Opioids in the Home Following Legitimate Opioid Prescribing in Children.
The overall objective of this study is to evaluate strategies to reduce unused opioids prescribed for pediatric acute post-surgical pain management.
- Trial name
- NCT04219397
- Testing
- Medication take back, Medication home disposal
- Where
- 2 sites in United States
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Indiana University
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