Clinical trials: Acute Pain, completed
Acute Otitis Media
Evaluation of Safety and Reduction of Ear Pain in Adults With Acute Otitis Media and Reduction of Ear Pain in Adults With Acute Otitis Media
The purpose of this study is to evaluate the Safety and Reduction of Ear Pain in Adults with Acute Otitis Media.
- Trial name
- NCT03766373
- Testing
- Drug: OP0201 20mg
- Where
- 2 sites in United States
- Volunteers
- 24 people
- Sponsor
- Novus Therapeutics, Inc
Laparoscopic Renal Surgery, Pain Management
Quadratus Lumborum Block : Effect on Acute Pain and Quality of Recovery After Laparoscopic Renal Surgery
This prospective, randomized study,control study aims to compare the analgesic effect,opioids consumption,quality of recovery,length of hospital stay and incidence of chronic pain,et al.
- Conditions
- Laparoscopic Renal Surgery, Pain Management, Nerve Block
- Trial name
- NCT02841982
- Testing
- single-injection QLB(quadratus lumborum block), Philip CX50 Ultrasound Scanner, PAJUNK StimuLong
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Cui Xulei
Rib Fracture
Ibuprofen Versus Dexketoprofen in Rib Fractures
The purpose of this study is to compare the pain-relieving effects of two different nonsteroidal anti-inflammatory drugs (NSAIDs), intravenous ibuprofen and intravenous dexketoprofen, in adults who present to the emergency…
- Trial name
- NCT07859631
- Testing
- Ibuprofen 800 mg, Dexketoprofen 50 mg
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people
- Sponsor
- Ankara City Hospital Bilkent
Brain and Central Nervous System Tumors, Chronic Myeloproliferative Disorders
Opioid Titration Order Sheet or Standard Care in Treating Patients With Cancer Pain
RATIONALE: An Opioid Titration Order Sheet that allows healthcare providers to adjust the dose and schedule of pain medication may help improve pain treatment for patients with cancer.
- Conditions
- Brain and Central Nervous System Tumors, Chronic Myeloproliferative Disorders, Leukemia, Lymphoma
- Trial name
- NCT00666211
- Testing
- educational intervention, Titrated pain management, questionnaire administration
- Where
- 11 sites in United States
- Volunteers
- 98 people
- Sponsor
- Vanderbilt-Ingram Cancer Center
Pain
Hydrocodone/Acetaminophen for Acute Pain Following Third Molar Tooth Extraction
The purpose of this study was to evaluate analgesic efficacy and safety of hydrocodone/acetaminophen compared to placebo in moderate to severe pain following molar extraction.
- Trial name
- NCT00935311
- Testing
- ABT-712 Extended-release, Hydrocodone/Acetaminophen Immediate-release
- Where
- 3 sites in United States
- Volunteers
- 122 people
- Sponsor
- AbbVie (prior sponsor, Abbott)
Restenosis, Stable Angina Pectoris
Intracoronary Stenting and Angiographic Results: Optimizing Treatment of Drug Eluting Stent In-Stent Restenosis 4
The purpose of the study is to determine whether scoring balloon (SCB) plus paclitaxel-coated balloon (PCB) is superior to PCB alone for the treatment of restenosis within "limus"-eluting stents (LES)
- Conditions
- Restenosis, Stable Angina Pectoris, Acute Coronary Syndrome
- Trial name
- ISAR-DESIRE 4 (NCT01632371)
- Testing
- Paclitaxel Eluting Balloon + Scoring Balloon, Paclitaxel Eluting Balloon
- Where
- 2 sites in Germany
- Volunteers
- 252 people
- Sponsor
- Deutsches Herzzentrum Muenchen
Acute Coronary Syndrome, Acute Myocardial Infarction
Comparison Between Ticagrelor Versus Very Low Dose Rivaroxaban With Clopidogrel
A total of 50 participants diagnosed with ACS (group A ticagrelor 180mg/d, n=25), group B (clopidogrel 75mg + rivaroxaban 5mg/ d, n=25)) were consecutively enrolled and treated with study drugs on top of aspirin (100mg/d) for 1…
- Conditions
- Acute Coronary Syndrome, Acute Myocardial Infarction, Unstable Angina
- Trial name
- NCT03481257
- Where
- South Korea
- Volunteers
- 56 people
- Sponsor
- Seoul National University Hospital
Pain, Acute, Opioid Use
Femoral Triangle Block With Popliteal Plexus Block Versus Femoral Triangle Block Versus Adductor Canal Block for TKA
In this study we wish to investigate the analgesic effect 3 different nerve block regimes in patients following primary total knee arthroplasty (TKA).
- Conditions
- Pain, Acute, Opioid Use, Analgesia
- Trial name
- NCT04854395
- Testing
- Marcain 5 mg/ml
- Where
- Denmark
- Volunteers
- 165 people
- Sponsor
- Regionshospitalet Silkeborg
Acute Pain, Bunion
Study of Wafermine™ for Post-bunionectomy or Abdominoplasty Pain
This study evaluates the safety and effectiveness of Wafermine™ for post-bunionectomy or post-abdominoplasty pain over a 24 hours period.
- Conditions
- Acute Pain, Bunion, Abdominoplasty
- Trial name
- NCT03246971
- Testing
- Wafermine™ 50 mg, Wafermine™ 75 mg, Wafermine™ 25 mg
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- iX Biopharma Ltd.
Thromboembolism
Michelangelo - Oasis 5
Study Objectives PRIMARY OBJECTIVE: To evaluate whether fondaparinux is at least as effective as or superior to enoxaparin in preventing death, myocardial infarction or refactory ischemia up to Day 9 in the acute treatment of…
- Trial name
- NCT00139815
- Testing
- Fondaparinux, enoxaparin
- Volunteers
- 20,078 people
- Sponsor
- GlaxoSmithKline
Low Back Pain
Effectiveness of Transcutaneous Electrical Nerve Stimulation in Patients With Acute Low Back Pain
Introduction: Low back pain is one of the most common complaints in doctors' offices, and acute low back pain is characterized by episodes of pain with less than three weeks duration.
- Trial name
- NCT02427425
- Testing
- TENS
- Volunteers
- 71 people
- Sponsor
- Federal University of São Paulo
Neck Pain
Acute Effects of Action Observation on Neck Pain
This study aims to assess the immediate effects of action observation therapy on the cervical muscles' strength, pain intensity, tactile acuity and pain pressure threshold in individuals with chronic nonspecific neck pain.
- Trial name
- NCT05078489
- Testing
- Action-observation therapy
- Where
- Portugal
- Volunteers
- 60 people
- Sponsor
- Aveiro University
Pain, Acute
Analgesic Effects of Cannabidiol for Simple Tooth Extractions in Dental Patients
The purpose of this study is to evaluate the analgesic effects of cannabidiol for patients who have undergone simple tooth extraction.
- Trial name
- SWAP (NCT04271917)
- Testing
- cannabidiol, acetaminophen 500mg and ibuprofen 200mg combo
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- University of Tennessee
Pain, Head, Pain, Acute
Single-Dose Bioavailability Study of Two Formulations of Ibuprofen and Pseudoephedrine Hydrochloride Tablets
Evaluation of the comparative bioavailability between two oral formulations containing ibuprofen 200 mg and pseudoephedrine 30 mg after a single dose in healthy subjects under fasting conditions.
- Conditions
- Pain, Head, Pain, Acute, Pain, Back, Fever
- Trial name
- NCT03429738
- Testing
- Ibuprofen/Pseudoephedrine HCl 200/30 mg Film-Coated Tablets, RhinAdvil Rhume 200 mg/30 mg Film-Coated Tablets
- Where
- Canada
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Institut für Pharmakologie und Präventive Medizin
Multiple Trauma, Acute Pain Due to Trauma
Evaluation of Effect of Intravenous Morphine vs Intravenous Ibuprofen and Acetaminophen vs Intravenous Ibuprofen
Pain is an inseparable symptom of fractures and is the most important and common symptom that brings patients to medical centers; Therefore, paying attention to pain and its control is very important in the examination and…
- Trial name
- NCT05630222
- Testing
- Ibuprofen 800 mg, Morphine Sulfate, Ibuprofen 400 mg plus Acetaminophen 1000 mg
- Where
- Iran
- Volunteers
- 150 people
- Sponsor
- Isfahan University of Medical Sciences
Peritonitis; Acute, Acute Appendicitis
Retrospective Comparison Between AirSeal® and Standard Insufflation in Appendicular Peritonitis
The AirSeal System Valve-less Trocar is known to decrease postoperative pain, consumption of analgesics, operating time, and length of stay in adults during robotic and laparoscopic procedures.
- Conditions
- Peritonitis; Acute, Acute Appendicitis, Postoperative Pain, Laparoscopy
- Trial name
- APPAS (NCT06734494)
- Testing
- Laparoscopic appendectomy Laparoscopic appendectomy with Airseal or with standard insufflation
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Destinval Christelle
Chest Pain Syndrome
Comprehensive Cardiothoracic Dual Source CT for the Early Triage of Patients With Acute Chest Pain
The purpose of this research is to determine the efficiency of a single dual source computed tomography (CT-DSCT) protocol to establish or exclude acute coronary syndrome (ACS), pulmonary embolism (PE) or aortic dissection (AD)…
- Trial name
- CAPTURE (NCT01067456)
- Testing
- Comprehensive Cardiothoracic CT arm
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- Massachusetts General Hospital
Vertebral Fracture, Osteoporotic Fractures
CCEF in the Treatment of Acute VFFs: Randomized Controlled Trial
in recent years the search for therapeutic protocols that could enhance the VFFs healing, thus reducing bed rest-related complications and improving the quality of life of osteoporotic patients.
- Trial name
- NCT05803681
- Testing
- Capacitive Coupled Electric Fields (CCEF), Calssic clinical protocol
- Volunteers
- 70 people
- Sponsor
- University of Bari Aldo Moro
Pain
Acute Pain Study Following Bunionectomy
The primary purpose of this study was to evaluate analgesic efficacy and safety of hydrocodone/acetaminophen extended release compared to placebo in the treatment of moderate to severe pain following bunionectomy.
- Trial name
- NCT01333722
- Testing
- Hydrocodone/Acetaminophen Extended Release
- Where
- 3 sites in United States
- Volunteers
- 100 people
- Sponsor
- AbbVie (prior sponsor, Abbott)
Acute Pain Due to Trauma
Paracetamol Vs Caffeine Vs Codeine in the Management of Post Traumatic Pain in Emergencies
The purpose of this study is to: Compare the effect of paracetamol alone against Paracetamol+Codeine association against the association of paracetamol + Cafeine in the treatment of post-traumatic acute pain of the limbs.
- Trial name
- NCT05229965
- Testing
- Paracetamol, Paracetamol Codeine, Paracetamol caféine
- Where
- Tunisia
- Volunteers
- 1,500 people
- Sponsor
- University of Monastir
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