Clinical trials: Acute Pain, completed
Postoperative Pain, Acute, Postoperative Nausea and Vomiting
The Impact of Breath Exercise Training on Postoperative Pain, Anxiety, and Nausea-Vomiting in General Surgery Patients
This study was conducted to determine the effect of breath exercise on post-operative anxiety level, pain, and nausea-vomiting after general surgery. This was a randomized, controlled experimental study.
- Conditions
- Postoperative Pain, Acute, Postoperative Nausea and Vomiting, Patient Relations, Nurse
- Trial name
- NCT06546514
- Testing
- Breath Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 149 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Fibromyalgia
Acute Effects of Exercise in Women With Fibromyalgia (FM)
The investigators previous studies of aerobic exercise in women with fibromyalgia (FM) have shown that exercise improves body functions and/or symptom severity in most patients, but not in all.
- Trial name
- NCT01592916
- Where
- Sweden
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Göteborg University
Primary Dysmenorrhea
Virtual Reality-Based Relaxation and Exergaming vs. Traditional Relaxation for Primer Dysmenorrhea
The goal of this clinical trial is to investigate the acute effects of virtual reality-based relaxation (immersive VR relaxation) and exergaming (non-immersive VR) compared to traditional Jacobson's relaxation on symptoms of…
- Trial name
- NCT06728306
- Testing
- Immersive Virtual Reality-Based Relaxation, Non-immersive VR-Based Exergaming, Jacobson's Relaxation
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 43 people
- Sponsor
- Trakya University
Laparoscopic Cholecystectomy, Pain
A Randomized, Double-Blind Study of the Efficacy and Safety of Valdecoxib Compared to Placebo for Treatment of Post- Cholecystectomy Surgery Pain
To evaluate the analgesic efficacy, general safety, and effects on health outcome measures and opioid-related symptoms of 2 valdecoxib dosing regimens compared with placebo in patients with moderate or severe pain following…
- Trial name
- NCT00661635
- Testing
- valdecoxib
- Where
- 65 sites in United States
- Volunteers
- 490 people
- Sponsor
- Pfizer
Refeeding Syndrome, Acute Abdomen
Refeeding Like Syndrome in Acute Disease
The refeeding syndrome has been reported without any evidence of prolopnged semistarvation, thus being different from the traditional disease.
- Trial name
- RLS (NCT04966780)
- Testing
- acute abdominal surgery
- Where
- Denmark
- Volunteers
- 48 people
- Sponsor
- Jens Rikardt Andersen
Pain, Acute
Impact of Vitamin C on Pain Detection and Tolerance Threshold
Non-opioid treatments are increasingly sought after for managing acute pain. Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) (e.g., Advil, Motrin, Naproxen) combined with acetaminophen (e.g., Tylenol) have become an alternative…
- Trial name
- NCT06971315
- Testing
- Vitamin C
- Where
- Canada
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal
Breast Cancer, Acute Postoperative Pain
Combined PECS II and Transversus Plane Blocks Versus Erector Spinae Block in Modified Radical Mastectomy
The aim of this study is to compare the total morphine consumption in the first 24 hour postoperative between combined modified pectoralis block (PECS II) and transversus plane block versus erector spinae block in modified…
- Trial name
- NCT03903224
- Testing
- Combined Modified Pectoralis and Transversus Plane Blocks, Erector Spinae block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Breast Cancer
Effect of a Topical Ketamine on Acute and Chronic Pain, Dose Finding
The aim of this study is to investigate the effect of addition of different doses of Ketamine locally in acute and chronic post-mastectomy pain after breast cancer surgery and on the probability of developing chronic…
- Trial name
- NCT03165149
- Testing
- group (A), group (B), group (c)
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Assiut University
Coronary Stenosis, Acute Coronary Syndrome
Multiomics and Imaging-based Assessment of Vulnerable Coronary Plaques in Acute Coronary Syndromes
The aim of Multiplaque clinical study is to assess the vulnerability degree of the atheromatous plaques, before and after a myocardial infarction (MI), based on multiomics analysis, associated with invasive and non-invasive data.
- Conditions
- Coronary Stenosis, Acute Coronary Syndrome, Acute Myocardial Infarction, Atheromatous Plaques
- Trial name
- MultiPlaque (NCT03391908)
- Testing
- cardiac imaging tests
- Where
- Romania
- Volunteers
- 100 people
- Sponsor
- Cardio Med Medical Center
Pain, Acute
Controlled Study to Assess the Efficacy and Safety of S-Ibuprofen Topical Gel 5% (AP0302) in the Treatment of DOMS
Phase 2 study designed to evaluated analgesic efficacy and safety of S-Ibuprofen Topical Gel 5%
- Trial name
- NCT03852459
- Testing
- S-Ibuprofen, Vehicle
- Where
- United States
- Volunteers
- 251 people, healthy volunteers welcome
- Sponsor
- Aponia Laboratories, Inc.
Acute Coronary Syndrome, Pulmonary Embolism
Prehospital Translation of Chest Pain Tools
Decision aids such as the HEART Pathway, Emergency Department Assessment of Chest Pain Score (EDACS), Revised Geneva Score and PERC Score have similar ability to accurately risk stratify Emergency Department (ED) patients with…
- Trial name
- RESCUE (NCT03494556)
- Testing
- Data Collection
- Where
- 2 sites in United States
- Volunteers
- 365 people
- Sponsor
- Wake Forest University Health Sciences
Cholecystitis, Gall Stone Pancreatitis
Randomized Control Trial of Intraperitoneal Bupivacaine During Cholecystectomy
Laparoscopic cholecystectomy (removal of the gall bladder via 'keyhole surgery') is a common procedure. This can be performed as an emergency operation when a patient has a complication of gall stones such as acute inflammation…
- Trial name
- NCT01528722
- Testing
- Bupivacaine, Normal saline
- Where
- United Kingdom
- Volunteers
- 42 people
- Sponsor
- University Hospitals Coventry and Warwickshire NHS Trust
Post Operative Pain, Acute, Chronic Post Surgical Pain
Continuous Epidural With Dexmedetomidine Adjuvant in Gynecologic Laparotomy
The goal of this clinical trial is to learn if adding a medication called dexmedetomidine to an epidural block works better than a standard epidural to control pain in women undergoing gynecologic laparotomy (abdominal surgery).
- Conditions
- Post Operative Pain, Acute, Chronic Post Surgical Pain, Gynecologic Disease
- Trial name
- NCT07292324
- Testing
- Dexmedetomidine & Bupivacaine., Bupivacain
- Where
- Indonesia
- Volunteers
- 62 people
- Sponsor
- Udayana University
Fracture, Pain
Racial and Ethnic Disparities in Acute Pain Control
We aim to compare pain management among three groups of ethnic disparity (ED) patients, Hispanics, non-Hispanic Blacks, non-Hispanic Whites, and assess whether the observed association between pain management and race/ethnicity…
- Trial name
- NCT00115180
- Testing
- No intervention
- Where
- 2 sites in United States
- Volunteers
- 285 people
- Sponsor
- Agency for Healthcare Research and Quality (AHRQ)
Hemophilia
Resistance Training With Blood Flow Restriction in Hemophilia
The main objectives of this study are to evaluate safety and chronic effects of a low-load resistance exercise intervention (elbow flexions and extensions, and knee extensions) with blood flow restriction in people with…
- Trial name
- HemoBFR (NCT05568524)
- Testing
- BFRT, Control
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- University of Valencia
Vitamin C, Post-mastectomy Pain Syndrome
Vitamin C on Acute and Chronic Post Mastectomy Pain
This prospective randomized double-blinded controlled study will be conducted to evaluate the effect of perioperative vitamin C on acute and chronic post mastectomy pain after breast cancer surgery
- Trial name
- NCT05770596
- Testing
- vitamin C group
- Where
- Egypt
- Volunteers
- 204 people
- Sponsor
- Tanta University
Acute Pain
A Study of Cebranopadol for the Treatment of Acute Pain After Abdominoplasty
The purpose of this study is to evaluate the efficacy and safety of Cebranopadol for acute pain after a Abdominoplasty.
- Trial name
- ALLEVIATE1 (NCT06545097)
- Testing
- Cebranopadol 400 ug, Cebranopadol 200 ug
- Where
- 4 sites in United States
- Volunteers
- 279 people
- Sponsor
- Tris Pharma, Inc.
Carotidynia
Medical Imaging Characteristics of Patient With Unclassified Acute Cervical Pain
Some cases of acute antero-lateral cervical pain cannot be accurately classified by medical imaging (ultrasound and/or magnetic resonance imaging and/or CT-scan) : imaging rules out carotid dissection, carotid occlusion or…
- Trial name
- RetroTIPIC (NCT03690882)
- Testing
- systematic review of medical imaging
- Where
- France
- Volunteers
- 47 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Acute Pain
Psychosocial Support for Pre-operative Pain and Distress
The purpose of this randomized study is to determine the impact of three different types of psychosocial support delivered by mental health professionals to pre-operative joint replacement patients.
- Trial name
- Mind-Body JRA (NCT03665727)
- Testing
- Mindfulness, Suggestion, Psychoeducation
- Where
- United States
- Volunteers
- 727 people
- Sponsor
- University of Utah
Acute Pain
A Study of Cebranopadol for the Treatment of Acute Pain After Bunionectomy
The purpose of this study is to evaluate the efficacy and safety of Cebranopadol for acute pain after a bunionectomy.
- Trial name
- ALLEVIATE2 (NCT06423703)
- Testing
- Cebranopadol, Oxycodone IR
- Where
- 10 sites in United States
- Volunteers
- 240 people
- Sponsor
- Tris Pharma, Inc.