Clinical trials: Acute Pain, completed
Pain Threshold, Pain Tolerance
Acute Effects of LLLT on Pain Threshold and Pain Tolerance
Pain is defined by the International Association for the Study of Pain as "an unpleasant sensory and emotional experience associated with, or resembling that associated with, actual or potential tissue damage." Low-Level Laser…
- Conditions
- Pain Threshold, Pain Tolerance, Acute Pain, Low-level Laser Therapy
- Trial name
- NCT07422272
- Testing
- Low-Level Laser Therapy (LLLT)
- Where
- Cyprus
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- European University of Lefke
Healthy Volunteers Are Studied
Pain Sensitivity in Acute Inflammatory Pain
Pain is a complex experience influenced by gender and genetics, and, by psychosocial and sensory experiences. Pain sensitivity is thus highly variable between individuals.
- Trial name
- PASORI (NCT01345877)
- Testing
- first degree cutaneous burn injury
- Where
- Denmark
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Acute Dental Pain
Evaluation of the Analgesic Efficacy of the Combination of Dexketoprofen + Paracetamol and the Combination of Naproxen Sodium + Codeine in Patients With Acute Dental Pain
Acute dental pain is one of the most challenging conditions to treat and manage in dental practice. The aim of this study was to compare the efficacy of naproxen sodium + codeine phosphate (550/30 mg) and dexketoprofen trometamol…
- Trial name
- NCT06916234
- Testing
- Dexketoprofen Trometamol + Paracetamol, Naproxen Sodium + Codeine Phosphate
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- ibrahim doğru
Acute Coronary Syndrome
A Comparison of Ticagrelor (AZD6140) and Clopidogrel in Patients With Acute Coronary Syndrome
Ticagrelor is a new, reversible binding, anti-platelet medication. Anti-platelet medications work to prevent the formation of blood clots.
- Trial name
- PLATO (NCT00391872)
- Testing
- Ticagrelor, Clopidogrel
- Where
- 672 sites in United States, Argentina and 42 more
- Volunteers
- 18,624 people
- Sponsor
- AstraZeneca
Chronic Pain, Musculoskeletal Pain
Bonipar for Acute and Chronic Musculoskeletal Pain
This study is a non-inferiority study comparing efficacy and onset of action between the herbal extracts topical solution, Bonipar, and diclofenac sodium topical solution, diclofenac topical solution 1.5%.
- Trial name
- NCT03471507
- Testing
- Bonipar, Diclofenac sodium topical solution 1.5%
- Where
- United States
- Volunteers
- 164 people
- Sponsor
- Winston Parris, MD
Pain, Acute, Pain, Chronic
The Impact of Music on Nociceptive Processing
The investigators are studying the ways that different music may change pain perception
- Conditions
- Pain, Acute, Pain, Chronic, Anxiety, Anxiety Disorders
- Trial name
- NCT04087564
- Testing
- music intervention
- Where
- United States
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Low Back Pain
The Efficacy of Dexketoprofen And Methylprednisolone in the Acute Low Back Pain
Many methods have been used in to treat low back pain. In this study, we aimed to investigate the efficacy of dexketoprofen alone and in combination with methylprednisolone in the treatment of low back pain in the emergency…
- Trial name
- Pain (NCT06932367)
- Testing
- Dexketoprofen (KETAVEL 50 mg/2 ml), Methylprednisolone (Corticosteroid)
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Ali Gur
Opioid Use, Acute Pain
Appropriate Opioid Quantities for Acute Pain - Pharmacist Study
Prescription opioids contribute to opioid related deaths, overdose and addiction. Unused prescribed opioids are not routinely being stored or disposed of appropriately and their availability is associated with harms.
- Trial name
- NCT04484610
- Testing
- Pharmacist Practice Change to Dispense Appropriate Opioid Quantities for Acute Pain
- Where
- Canada
- Volunteers
- 205 people
- Sponsor
- Centre for Addiction and Mental Health
Acute Pain Management, Gynecologic Surgical Procedures
Comparison of Quadratus Lumborum Block Types in Open Gynecologic Surgery
This study was conducted to evaluate the effectiveness of Quadratus Lumborum Type 1 and Type 2 blocks on postoperative acute pain in gynecological operations performed with a Pfannenstiel incision.
- Conditions
- Acute Pain Management, Gynecologic Surgical Procedures, Quadratus Lumborum Block
- Trial name
- NCT07395440
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Ankara Etlik City Hospital
Acute Pain, Hysteroscopy
Virtual Reality and Outpatient Hysteroscopy
TITLE Virtual Reality (VR) as a Distraction technique for management of acute pain at Outpatient Hysteroscopy DESIGN Randomised Control Trial (RCT) with Mixed methods - Qualitative and quantitative AIMS To study the role of…
- Trial name
- VISTA (NCT03699280)
- Testing
- Virtual Reality
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Imperial College London
Long COVID, Pain
Pain Relief With Integrative Medicine (PRIMe)?: Feasibility of Acupuncture for Long COVID
The goal of this preliminary study is to test methods and procedures to be used in a fully-powered trial to evaluate acupuncture treatment effectiveness.
- Trial name
- NCT06476496
- Testing
- Acupuncture
- Where
- United States
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- University of Washington
Cholecystitis
Harmonic in Laparoscopic Cholecystectomy for Acute Cholecystitis
In the developmental stage of laparoscopic cholecystectomy it was considered 'unsafe' or 'technically difficult' to perform laparoscopic cholecystectomy for acute cholecystitis.
- Trial name
- HAC (NCT00746850)
- Testing
- early LC within 72 hours after the diagnosis with H (Harmonic), early LC within 72 hours after the diagnosis with MD (Monopolar Diathermy)
- Where
- Italy
- Volunteers
- 42 people
- Sponsor
- University of Bologna
Acute Back Pain
Phase 3 Study to Evaluate the Efficacy and Safety of DW-1030 and Eperisone HCl in Acute Back Pain Patients
The purpose of this clinical study is to determine whether or not DW-1030 is not inferior to eperisone HCl in efficacy and safety.
- Trial name
- NCT02040415
- Testing
- DW-1030(eperisone HCl) 75mg, Myonal Tab.(eperisone HCl) 50mg
- Volunteers
- 242 people
- Sponsor
- Daewon Pharmaceutical Co., Ltd.
Microbial Substitution, Tryptophan Metabolism Alterations
Impact of Gut Microbiota and Tryptophan Metabolites on Acute Pain in Lumbar Disc Herniation Surgery Patients
It is well-established that the gut microbiota plays a crucial role in various pain mechanisms, including visceral pain, inflammatory pain, headache, neuropathic pain, and opioid tolerance.
- Conditions
- Microbial Substitution, Tryptophan Metabolism Alterations, Postoperative Pain, Acute
- Trial name
- NCT06502223
- Testing
- Pain Perception in Patients Undergoing Lumbar Disc Herniation Surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 37 people
- Sponsor
- Dokuz Eylul University
Acute Postoperative Pain, Chronic Postoperative Pain
Menstrual Phase and Postoperative Pain
Fluctuations of female sex hormones during the menstrual cycle influence pain perception. Endogenous pain is pronounced in the follicular phase of the menstrual cycle.
- Trial name
- NCT02137135
- Testing
- HAD scale, The SF 12 test, Visual analogue score
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Stable Angina, Acute Coronary Syndrome
Novasight Hybrid Intravascular Ultrasound and Optical Coherence Tomography System (IVUS OCT)
Collection of coronary images with a hybrid IVUS OCT system.
- Trial name
- NCT03484975
- Testing
- Observation group
- Where
- Canada
- Volunteers
- 23 people
- Sponsor
- Conavi
Pain, Acute, Analgesia
Preanesthetic Analgesia/Nociception Index (ANI) and Propofol Injection Pain
Recently, Analgesia Nociception Index (ANI) has been evaluated for objectively measuring peri-operative pain and to guide intra-operative opioid administration during various surgeries.
- Conditions
- Pain, Acute, Analgesia, Nociceptive Pain
- Trial name
- NCT05049577
- Testing
- Analgesia/Nociception Index (ANI)
- Where
- South Korea
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Wonkwang University Hospital
Acute Pain
Intranasal Ketorolac for Postsurgical Pain in Dental Implant Patients
The surgical placement of dental implants is presently a common procedure performed by oral surgeons, periodontists, and general dentists.
- Trial name
- NCT01490931
- Testing
- Ketorolac Nasal Spray
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Hersh, Elliot V., DMD, MS, PhD
Pain Sensation, Hyperalgesia
Pain Response to Cannabidiol in Induced Acute Nociceptive Pain, Allodynia and Hyperalgesia By Using a Model Mimicking Acute Pain in Healthy Adults
This study is to investigate the effect of CBD on acute pain in healthy volunteers in a well-established acute pain model.
- Conditions
- Pain Sensation, Hyperalgesia, Allodynia
- Trial name
- CANAB I (NCT03985995)
- Testing
- CBD 800 mg p.o
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Acute Postoperative Pain
Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Profile of HYR-PB21 in Healthy Volunteers
This study is the first time into human study (FTIH) for HYR-PB21 for injection. The study will evaluate the safety, pharmacokinetics (PK) and pharmacodynamics (PD) of single ascending and single subcutaneous dose of HYR-PB21 for…
- Trial name
- NCT04169256
- Testing
- HYR-PB21, Liposomal bupivacaine, Normal Saline
- Where
- Australia
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Fruithy Medical Pty Ltd
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