Clinical trials: Acute Pain, completed
Pain, Acute, Cognition
Effects of Acute Pain on Cognitive Performance in Young Adults
The effects of pain on cognitive performance have not been thoroughly investigated. Broadly, the purpose of this research is to investigate the effects of acute pain on performance of a variety of cognitive performance measures.
- Trial name
- NCT05625776
- Testing
- pain delivery with capsaicin and heat, distractor delivery with sensory TENS
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Delaware
Osteoarthritis, Rheumatoid Arthritis
A Phase 1 Clinical Trial to Evaluate the Safety and Pharmacokinetic Characteristics of DW1809-T2
Randomized, Open-label, Oral, Single-dose, two-Sequence, four-Period, crossover study
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Back Pain, Acute Upper Respiratory Tract Infection
- Trial name
- NCT05214690
- Testing
- DW1809-T2, DW1809-1
- Where
- South Korea
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Daewon Pharmaceutical Co., Ltd.
Acute Pain, Regional Anesthesia
EOIB for Laparoscopic Sleeve Gastrectomy
n obese patients, adequate pain relief in the postoperative period is a crucial parameter that affects patient comfort and hospital stay.
- Conditions
- Acute Pain, Regional Anesthesia, Morbid Obesity
- Trial name
- NCT07101835
- Testing
- Bilateral ultrasound guided external oblique intercostal block (EOIB), ıv morphine PCA
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Ondokuz Mayıs University
Musculoskeletal Pain, Analgesia
Intramuscular Ketorolac at Two Single-Dose Regimens
The purpose of this study was to evaluate a single 15 mg intramuscular (IM) dose of ketorolac for analgesic non-inferiority versus a single 60 mg IM dose for the treatment of acute MSK pain in a military emergency department (ED)…
- Conditions
- Musculoskeletal Pain, Analgesia, Adverse Event
- Trial name
- NCT04763876
- Testing
- Ketorolac Injection 15 mg, Ketorolac Injection 60 mg
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- William Beaumont Army Medical Center
Major Depressive Disorder
A Study in Depression and Associated Painful Physical Symptoms
The purpose of this study is to find out if 60 mg of duloxetine given once a day by mouth for 8 weeks to patients diagnosed with major depressive disorder, who also report associated painful physical symptoms, is better than…
- Trial name
- NCT01070329
- Testing
- Duloxetine
- Where
- 34 sites in United States, Puerto Rico
- Volunteers
- 527 people
- Sponsor
- Eli Lilly and Company
Acute Pain, Chronic Pain
Ketamine as Adjunctive Analgesic With Bupivacaine in Paravertebral Analgesia for Breast Cancer Surgery
This study aims to investigate the safety and the analgesic efficacy of adding Ketamine to bupivacaine 0.25% in thoracic PVB in patients undergoing modified radical mastectomy.
- Trial name
- NCT02462681
- Testing
- paravertebral block
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Assiut University
Pain, Postoperative
Efficacy and Safety of Intranasal Morphine for Pain After Elective Orthopedic Surgery
Multiple-center, multiple-dose, randomized, double-blind, six-arm, active- and placebo-controlled study in patients with moderate to severe post-surgical pain from elective orthopedic surgery with safety observed for a total of…
- Trial name
- NCT00390039
- Testing
- Intranasal Morphine, IV morphine
- Where
- 7 sites in United States
- Volunteers
- 256 people
- Sponsor
- Javelin Pharmaceuticals
Postoperative Pain
Auricular Acupuncture for Pain Relief After Ambulatory Knee Arthroscopy
The aim was to investigate whether auricular acupuncture is superior to sham acupuncture in relief of acute postoperative pain and in reduction of analgesics consumption on demand and their side effects in patients after…
- Trial name
- NCT00233857
- Testing
- Auricular acupuncture
- Where
- Germany
- Volunteers
- 120 people
- Sponsor
- University Medicine Greifswald
Infusion, Dexmedetomidine
Infusion of Dexmedetomidine Versus Lidocaine in Management of Acute Postoperative Pain After Modified Radical Mastectomy
This study aims to compare the effect of intraoperative intravenous infusion of dexmedetomidine and lidocaine in the management of acute postoperative pain after mastectomy.
- Conditions
- Infusion, Dexmedetomidine, Lidocaine, Acute
- Trial name
- NCT06974656
- Testing
- Dexmedetomidine, Lidocaine
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Low Back Pain, Medicine, Korean Traditional
The Effectiveness and Safety of T-MSAT on Inpatients With Acute Low Back Pain Caused by Traffic Accidents : A Randomized Controlled Trial
This study is a single blind, randomized controlled trial. condition/disease: acute low-back pain treatment/intervention: Motion Style Acupuncture Treatment using Traction (T-MSAT)
- Trial name
- NCT04554446
- Testing
- T-MSAT(Motion style acupuncture treatment using traction), Korean medicine treatment
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Jaseng Medical Foundation
Breast Cancer, Mastectomy
Music Intervention for Preoperative Anxiety and Acute Pain Among Mastectomy Patients
Anxiety is a common thing that patients experience when they are preparing to have a surgery. When this anxiety is not properly treated, the patients tend to consume more drugs in the operating room and it also cause their pain…
- Conditions
- Breast Cancer, Mastectomy, Pain, Postoperative
- Trial name
- NCT04824183
- Testing
- Music intervention
- Where
- 3 sites in Malawi, Nigeria
- Volunteers
- 36 people
- Sponsor
- Chinese University of Hong Kong
Participants With Acute Moderate to Severe Pain Following Abdominal Surgery
Efficacy and Safety of Intravenous Meloxicam in Subjects With Moderate-to-severe Pain Following Abdominal Surgery
This study aims to evaluate the analgesic efficacy and safety of meloxicam injection in subjects with moderate-to-severe pain following abdominal surgery.
- Trial name
- NCT06904248
- Testing
- Meloxicam Injection, Sodium Chloride Injection
- Where
- 18 sites in China
- Volunteers
- 224 people
- Sponsor
- Yangtze River Pharmaceutical Group Co., Ltd.
Acute Pain
Evaluation of a New Pain Management Protocol Involving Intranasal Sufentanil in the Emergency Room.
Until now, the Mulhouse emergency department used a protocol for severe pain based on morphine titration. In order to relieve patients' pain more quickly, a new protocol was implemented based on the use of intranasal sufentanil.
- Trial name
- SUURGE (NCT05498831)
- Testing
- Pain assessment at 15 minutes, 30 minutes, 60 minutes, 120 minutes after initial assessment by the triage nurse
- Where
- France
- Volunteers
- 245 people
- Sponsor
- Groupe Hospitalier de la Region de Mulhouse et Sud Alsace
Pain, Acute, Itch
The Effect of Halophyte-based Cream on Pain and Itch
In this study the investigators wish to investigate whether halophyte-based cream applied to the skin can reduce itch applied by means of small needles from the plant mucuna pruriens (also called cowhage) or by histamine (an…
- Trial name
- NCT04635254
- Testing
- Halophites-based cream 24 hours, Halophites-based cream 48 hours, Vehicle cream 24 hours
- Where
- Denmark
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Acute Pain Due to Trauma, Analgesia
Timecost of Intranasal Versus Intravenous Analgesia in Traumatic Pain
Prehospital treatment of acute traumatic pain is common in military practice. Analgesics are usually administered intravenously (IV).
- Trial name
- NCT06351137
- Testing
- Intravenous administration, Intranasal administration
- Where
- Netherlands
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Migraine, Pain
Nitrous Oxide for Acute Migraine Pain in the Emergency Room (ED)
BACKGROUND Migraine headaches account for 8-18% of all headaches seen in pediatric emergency rooms. Standard treatment includes IV pain medications, anti-emetics, and IV fluids.
- Trial name
- NCT01287052
- Testing
- Nitrous Oxide
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Children's Hospitals and Clinics of Minnesota
Pain, Nausea
A Double-Blind, Randomized, Active- and Placebo-Controlled, Multiple-Dose Multi-Center Phase 3 Study of the Safety and Efficacy of CL-108 in the Treatment of Moderate to Severe Acute Pain and Opioid-Induced Nausea and Vomiting (OINV)
The objectives of this study are to compare the occurrence and severity of opioid-induced nausea and vomiting (OINV) associated with CL-108 to Norco®, and to demonstrate the efficacy of CL-108 when compared to placebo for the…
- Conditions
- Pain, Nausea, Vomiting
- Trial name
- NCT02462811
- Testing
- CL-108 (hydrocodone 7.5 mg, acetaminophen 325 mg, promethazine 12.5 mg), Norco (hyrdocodone 7,5 mg, acetaminophen 325 mg)
- Where
- United States
- Volunteers
- 552 people
- Sponsor
- Joseph Hazelton
Pain, Postoperative, Pain, Acute
Comparison of Quadratus Lumborum Intramuscular and Transmuscular in Postoperative Pain
Acute pain is reported in approximately 80% of patients undergoing postoperative care for various types of surgical procedures in the United States.
- Conditions
- Pain, Postoperative, Pain, Acute, Cesarean Section Complications
- Trial name
- NCT05005871
- Testing
- Quadratus lumborum block after C-section surgery as postoperative pain management
- Where
- Indonesia
- Volunteers
- 48 people
- Sponsor
- Udayana University
Acute Low Back Pain
An Educational and Exercise Program as Secondary Prevention of Recurrent Lower Back Pain in Healthcare Workers
At Lyon University Medical Center, back problems are the leading cause of sick leave. The course of lower back pain is usually relatively short (recovery occurs within 4 to 6 weeks in 90% of cases).
- Trial name
- PRESLO (NCT00782925)
- Testing
- educational program, exercise program, Self-led exercises
- Where
- France
- Volunteers
- 351 people
- Sponsor
- Hospices Civils de Lyon
Pain, Acute, Anesthesia, Local
Variable Perception of Cutaneous Stimulation
Perception of cutaneous sensory stimulation shows a large range of variability across multiple populations. Understanding this variability is critical to medical practice as interpretation of discomfort and pain is critical to…
- Conditions
- Pain, Acute, Anesthesia, Local, Dermatology/Skin - Other
- Trial name
- NCT03467685
- Testing
- Vibratory Anesthetic Device (VAD)
- Where
- United States
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh