Clinical trials: Acute Pain, completed
Pain, Acute, Pain, Chest
Transversus Thoracic Muscle Plane Block for Open Heart Surgery
Poststernotomy pain is a complication of cardiac surgery. Poorly controlled pain is associated with myocardial ischemia, cardiac arrhythmias, hypercoagulability, pulmonary complications, and increased rates of delirium and wound…
- Trial name
- TTMP (NCT04094532)
- Testing
- Bupivacaine, Saline
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Ataturk University
Postoperative, Acute Pain
TEAS-induced Analgesia: Dual vs Single Acupoints
The purpose of this study is to evaluate the effects of transcutaneous electric acupoint stimulation(TEAS) at single acupoint or dual acupoints on opioid consumption and postoperative pain in patients undergoing radical mastectomy
- Conditions
- Postoperative, Acute Pain, Chronic Pain
- Trial name
- TADS (NCT02543580)
- Testing
- transcutaneous electric acupoint stimulation, electrode attached but no stimulation
- Where
- China
- Volunteers
- 153 people
- Sponsor
- Xijing Hospital
Neck Pain, Myofascial Pain Syndrome
ACUTE EFFECT OF DIAPHRAGMATIC BREATHING ON POSTOPERATIVE UPPER TRAPEZIUS PAIN
This randomized controlled trial aims to investigate the acute effects of diaphragmatic breathing exercises added to soft tissue mobilization and percussive therapy on pain intensity, functional disability, and pressure pain…
- Conditions
- Neck Pain, Myofascial Pain Syndrome, Work-Related Musculoskeletal Disorders
- Trial name
- TRAP-BREATHE (NCT07634588)
- Testing
- Diaphragmatic Breathing Exercise, Soft Tissue Mobilization, Percussive Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people
- Sponsor
- Istanbul Aydın University
Virtual Reality, Acute Postoperative Pain
Effect of Virtual Reality on Patients With Acute Pain After Thoracoscopic Surgery
Immersive virtual reality (VR) as a non-pharmaceutical technology may deliver effective behavioral therapies for postsurgical patients with acute pain.
- Conditions
- Virtual Reality, Acute Postoperative Pain, Thoracic Surgery, Video-Assisted
- Trial name
- NCT05926817
- Testing
- QTC-VR headsets
- Where
- China
- Volunteers
- 61 people
- Sponsor
- Tianjin Medical University
Other Acute Postoperative Pain
Study of Diclofenac Capsules to Treat Pain Following Bunionectomy
The purpose of this study is to determine whether Diclofenac [Test] Capsules are safe and effective for the treatment of bunionectomy pain.
- Trial name
- NCT01462435
- Testing
- Diclofenac Test (lower dose), Diclofenac Test (upper dose), Celecoxib
- Where
- 4 sites in United States
- Volunteers
- 428 people
- Sponsor
- Iroko Pharmaceuticals, LLC
Acute Coronary Syndrome, Non-ST Elevation (NSTEMI) Myocardial Infarction
An Efficacy and Outcome Study of Supplemental Oxygen Treatment in Patients With Suspected Myocardial Infarction
The use of supplemental oxygen in the setting of suspected acute myocardial infarction (AMI) is manifested in international treatment guidelines and established in prehospital and hospital clinical routine throughout the world.
- Conditions
- Acute Coronary Syndrome, Non-ST Elevation (NSTEMI) Myocardial Infarction, Acute ST Segment Elevation Myocardial Infarction, Angina, Unstable
- Trial name
- DETO2X-AMI (NCT01787110)
- Testing
- Oxygen
- Where
- 34 sites in Sweden
- Volunteers
- 6,629 people
- Sponsor
- Karolinska Institutet
Pain, Postoperative
Single Dose Preoperative Gabapentin Use in Minimally Invasive Hysterectomy for Acute Pain Management
The purpose of the investigators' study is to assess the efficacy of a single dose of preoperative gabapentin within an enhanced recovery after surgery protocol in acute postoperative pain reduction for women undergoing a…
- Trial name
- NCT02703259
- Testing
- Gabapentin, Acetaminophen, Celecoxib
- Where
- United States
- Volunteers
- 137 people, healthy volunteers welcome
- Sponsor
- Christiana Care Health Services
Chronic Postoperative Pain
Transition From Acute to Chronic Pain After Inguinal Hernia, Hysterectomy and Thoracotomy: Analysis of Risk Factors and Association With Genetic Polymorphisms
The treatment of postoperative pain continues to be inadequate in the investigators practice setting. Inadequate pain treatment not only contributes to postoperative complications in the short term but can also be a factor that…
- Trial name
- NCT01510496
- Testing
- Inguinal herniorraphy., Hysterectomy., Thoracotomy .
- Where
- 26 sites in Spain
- Volunteers
- 3,979 people
- Sponsor
- Fundacion IMIM
Knee Arthroscopy Surgery, Knee Acute and Chronic Pain
Arthroscopic Infrapatellar Fat Pad Release and Mesenchymal Stem Cell Mobilization
This prospective, single-center, paired-sample clinical laboratory study evaluated whether controlled mechanical release of the infrapatellar fat pad during knee arthroscopy increases the number of intra-articular cells with a…
- Conditions
- Knee Arthroscopy Surgery, Knee Acute and Chronic Pain, Meniscal Tears
- Trial name
- IP-MSC-RELEASE (NCT07736716)
- Testing
- Controlled Mechanical Release of the Infrapatellar Fat Pad
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Ankara City Hospital Bilkent
Hip Fractures, Acute Pain
PENG Block for Traumatic Hip Fracture in the Emergency Department
The study is a multicenter single-blinded randomized comparative trial. Adult patients older than 20 years of age presenting with acute hip fracture in emergency department between January 1st, 2021 and December 31st, 2021 will…
- Conditions
- Hip Fractures, Acute Pain, Emergency Department
- Trial name
- NCT04997785
- Testing
- Ultrasound-guided Pericapsular Nerve Group (PENG) Block
- Where
- Taiwan
- Volunteers
- 65 people
- Sponsor
- Dalin Tzu Chi General Hospital
Pain, Acute
Bupivacaine vs Oxybuprocaine Topical Anesthesia in IVI
comparing two local anaesthetic agents, Bupivacaine 0.5% versus Oxybuprocaine used topically to provide surface anaesthesia before IVI procedures.
- Trial name
- NCT05069350
- Testing
- bupivacaine 0.5% and oxubuprocaine
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Research Institute of Ophthalmology, Egypt
Pain
Pharmacokinetics & Safety of Diclofenac Potassium Oral Solution in Ped. Subjects (2-12 Yrs) With Mild-Mod. Acute Pain
As part of the Pediatric Research Equity Act (PREA) commitment, the objectives of the study are to characterize the pharmacokinetic (PK) profile and to determine the safety and tolerability of diclofenac potassium oral solution…
- Trial name
- NCT02287350
- Testing
- diclofenac potassium oral solution
- Where
- 5 sites in United States
- Volunteers
- 51 people
- Sponsor
- Depomed
Pain
Comparative Efficacy of 4 Oral Analgesics
The purpose of this study is to perform a randomized, double blind 4-arm clinical trial of the comparative efficacy of 4 oral analgesics in the initial management of acute musculoskeletal extremity pain presenting to the ED.
- Trial name
- NCT02455518
- Testing
- Oxycodone/acetaminophen, Hydrocodone/acetaminophen, Codeine/acetaminophen
- Where
- United States
- Volunteers
- 416 people
- Sponsor
- Montefiore Medical Center
Opioid Use, Opioid Prescribing
Variation in Opioid Prescribing and Use for Acute Pain in Diverse Populations
This study will characterize patient pain and opioid use after an initial opioid prescription for acute pain.
- Trial name
- NCT04509115
- Testing
- Short-acting opioid prescription for acute pain
- Where
- 5 sites in United States
- Volunteers
- 1,709 people
- Sponsor
- Yale University
Pain, Acute
Lidocaine Before Esophageal Manometry and Ambulatory pH Monitoring
A randomized controlled trial comparing esophageal manometry and ambulatory pH monitoring test tolerance in the presence versus in the absence of topical lidocaine.
- Trial name
- NCT03967197
- Testing
- Saline spray, Lidocaine Hydrochloride
- Where
- Canada
- Volunteers
- 304 people, healthy volunteers welcome
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Pain, Nausea
A Controlled Study to Determine the Efficacy and Safety of CL-108 5 mg for Acute Pain and the Prevention of OINV
To determine the analgesic efficacy of CL-108 5 mg by comparison with placebo and the anti-emetic efficacy of CL-108 5 mg by comparison with hydrocodone 5 mg/acetaminophen 325 mg.
- Conditions
- Pain, Nausea, Vomiting
- Trial name
- NCT03657810
- Testing
- CL-108 5 mg, Norco
- Where
- 5 sites in United States
- Volunteers
- 349 people
- Sponsor
- Charleston Laboratories, Inc
Hallux Valgus
A Study to Evaluate the Effectiveness and Safety of Tapentadol (CG5503) in the Treatment of Acute Pain From Bunionectomy Compared With Placebo
The purpose of this study is to evaluate the analgesic efficacy and safety of tapentadol immediate-release (IR [CG5503]) for use in the relief of moderate to severe acute pain, compared with placebo, in adult Taiwanese patients…
- Trial name
- NCT01813890
- Testing
- Tapentadol IR 50 mg, Tapentadol IR 75 mg
- Where
- 3 sites in Taiwan
- Volunteers
- 60 people
- Sponsor
- Janssen-Cilag International NV
Pain Management
Analgesic Efficacy of (MSIR)/Acetaminophen vs. Oxycodone/Acetaminophen (Percocet)
Oxycodone and Hydrocodone are the most commonly used oral opioid analgesics in the emergency department and in outpatient settings.
- Trial name
- NCT03088826
- Testing
- Morphine Sulfate, Oxycodone, Acetaminophen
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Antonios Likourezos
Pain, Postoperative, Acute Pain
The Effects of Body Mass Index on Thoracic Paravertebral Block Analgesia
Obesity has become one of the world's leading health problems. It is known that obesity causes many diseases and negatively affects the quality of life.
- Conditions
- Pain, Postoperative, Acute Pain, Thoracic Paravertebral Block, Body Mass Index
- Trial name
- NCT05357976
- Testing
- Thoracic Paravertebral Block
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Ankara City Hospital Bilkent
Unstable Angina, Myocardial Infarction
Early Versus Delayed Timing of Intervention in Patients With Acute Coronary Syndromes
The timing of intervention study is a prospective, randomized, international, multicentre comparison of the relative efficacy, safety, and cost effectiveness of a management strategy of coronary angiography and intervention…
- Trial name
- TIMACS (NCT00552513)
- Testing
- Early Coronary Intervention, Delayed Coronary Intervention
- Where
- Canada
- Volunteers
- 3,031 people
- Sponsor
- Population Health Research Institute
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