Clinical trials: Acute Pain, completed
Anesthesiology, Orthopedic
PO Pain Management With Extended-release Dinalbuphine Sebacate in Patients Undergoing Arthroscopic Shoulder Surgery
Postoperative pain is common, and the pain intensity can be moderate to severe depending on the site of surgery during the first few days after surgery, and an estimated 15% to 45% experience chronic postsurgical pain.
- Trial name
- NCT05115955
- Testing
- DS group, Control group
- Where
- Taiwan
- Volunteers
- 76 people
- Sponsor
- Tri-Service General Hospital (TSGH)
Neuropathy, Digestive Cancer System
Prevention of Oxaliplatin-induced Neuropathic Pain by a Specific Diet
Use lay language. Oxaliplatin is a reference anticancer drug in the treatment of colorectal cancer. However, its use is hampered by a specific neurotoxicity, which is characterized by acute thermal hypersensitivity, notably to…
- Trial name
- NEUROXAPOL (NCT01775449)
- Testing
- Polyamines depleted diet, associating Polydol® cans and predefined menus low in polyamines
- Where
- France
- Volunteers
- 80 people
- Sponsor
- University Hospital, Clermont-Ferrand
Lordosis, Low Back Pain
Comparing the Effects of Muscle Energy Technique Versus Myofascial Mobilization in Managing Sub-acute Low Back Pain
Institute for Clinical Systems Improvement (ICSI) defines sub-acute low back pain as low back pain lasting between 4 and 12 weeks.
- Trial name
- NCT05428280
- Testing
- Physiotherapy, Muscle Energy technique, Myofacial mobilization
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Dow University of Health Sciences
Lower Abdominal Pain, Right Iliac Fossa Pain
Non Operative Treatment for Acute Appendicitis
Case control studies that randomly assign patients to either surgical or non-surgical treatment yield a relapse rate of approximately 14% at one year.
- Conditions
- Lower Abdominal Pain, Right Iliac Fossa Pain, Acute Appendicitis
- Trial name
- NOTA (NCT01096927)
- Testing
- Amoxicillin and Clavulanic Acid
- Where
- Italy
- Volunteers
- 160 people
- Sponsor
- Maggiore Bellaria Hospital, Bologna
Musculoskeletal Chest Pain, Non-cardiac Chest Pain
Treatment Study Comparing Manual Treatment or Advice in Acute, Musculoskeletal Chest Pain
Acute chest pain is a common cause of hospital admission. Active approaches are directed towards diagnosis and treatment of potentially life threatening conditions, especially acute coronary syndrome and coronary artery disease.
- Conditions
- Musculoskeletal Chest Pain, Non-cardiac Chest Pain, Undiagnosed Chest Pain
- Trial name
- CARPA (NCT00462241)
- Testing
- chiropractic treatment, Self-management
- Where
- Denmark
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Clinical Locomotion Science
Cephalalgia
Protocol to Ease Acute Cephalalgia in Emergency-department
The purpose of this study is to determine if the use of a therapeutic and global protocol to relieve cephalalgia is helpful in the emergency department of Grenoble University Hospital.
- Trial name
- PEACE (NCT02236442)
- Testing
- Recommendation to use global headache treatment protocol
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Grenoble
Sphenopalatine Ganglion Nerve Block
Sphenopalatine Ganglion Block Study
The goal of this clinical trial is to compare the administration and dosage of bupivacaine for sphenopalatine ganglion (SPG) nerve block.
- Trial name
- NCT05707754
- Testing
- Bupivacaine, angiocatheter
- Where
- United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Acute Traumatic Pain
Morphine-Midazolam in Pre-hospital Traumatic Patients With Severe Acute Pain
Administration of midazolam with morphine in patients with severe acute pain is a routine practice in the management of pre- and post-operative patients but has not been evaluated in pre-hospital setting.
- Trial name
- Morphine-Mida (NCT01731184)
- Testing
- Midazolam
- Where
- 4 sites in France
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier de Cornouaille
Pain, Acute, Acute Pain
Open-label, Crossover, Food Effect Study to Evaluate CT-044 in Healthy Human Volunteers
This open-label study will be conducted to assess the bioavailability and PK of oral single doses of CT-044 following administration with and without food and to evaluate the safety and tolerability of CT-044 when given with and…
- Conditions
- Pain, Acute, Acute Pain, Surgery, Neuropathy
- Trial name
- NCT04252833
- Testing
- CT-044
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Lotus Clinical Research, LLC
Acute Otitis Externa
A Phase III Study of an Otic Formulation in Acute Otitis Externa
The purpose of this study is to determine if an otic formulation is safe and effective for the treatment of acute otitis externa (AOE).
- Trial name
- NCT00750633
- Testing
- Moxidex otic solution, Moxifloxacin otic solution, Dexamethasone phosphate otic solution
- Volunteers
- 990 people
- Sponsor
- Alcon Research
Muscle Soreness, Muscle Weakness
Lumbosacral Muscle Sensitivity & Pressure Pain Threshold After Kettlebell Swings
The primary purpose of the study is to assess the muscle contractility and sensitivity of lumbar erector spinae, biceps femoris, and gluteus maximus short-term response to Tabata kettlebell swing protocol.
- Conditions
- Muscle Soreness, Muscle Weakness, Muscle Tenderness
- Trial name
- NCT05607212
- Testing
- Kettlebell Swing, Isometric Hold, Control
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Central Florida
Chemotherapeutic Agent Toxicity, Neurotoxicity
Acute Pain Caused by Paclitaxel in Patients With Cancer
RATIONALE: Gathering information over time from patients receiving paclitaxel for cancer may help doctors learn more about pain caused by paclitaxel and plan the best treatment.
- Conditions
- Chemotherapeutic Agent Toxicity, Neurotoxicity, Pain, Unspecified Adult Solid Tumor, Protocol Specific
- Trial name
- NCT00860041
- Testing
- pain questionnaires
- Where
- 279 sites in United States
- Volunteers
- 306 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Low Back Pain
Randomized, Double Blind, Multicenter Study of the Safety and Efficacy of Valdecoxib 40 mg Once Daily Compared With Diclofenac 75 mg Twice Daily in Acute Low Back Pain
The pain relief, safety, and tolerability of valdecoxib 40 mg once daily compared with diclofenac 75 mg twice daily for acute low back pain was studied.
- Trial name
- NCT00649610
- Testing
- valdecoxib, diclofenac
- Where
- 29 sites in Argentina, Brazil and 7 more
- Volunteers
- 340 people
- Sponsor
- Pfizer
Acute Low Back Pain, Physical Activity
Acute Low Back Pain: Causes, Mechanisms, Treatment and Followup
The purpose of this study is to investigate acute low back pain, its origin, mechanisms, the cause of pain, evaluation of treatments and development.
- Trial name
- ALBP (NCT02517762)
- Testing
- Physical activity
- Volunteers
- 99 people
- Sponsor
- Göteborg University
Pain
Optimal Dose of i.v Oxycodone for Postoperative Pain
Postoperative pain control is required after major abdominal surgery, including laparoscopic colorectal surgery. Intravenous oxycodone is widely used for postoperative acute pain control mainly in Europe.
- Trial name
- NCT02732262
- Testing
- Oxycodone, 1.00 mg dose, Oxycodone, 0.03 mg/kg dose, Oxycodone, 0.02 mg/kg dose
- Where
- South Korea
- Volunteers
- 134 people
- Sponsor
- Seoul National University Hospital
Acute Coronary Syndrome, Chest Pain
Database of Patients Undergoing Cardiac Computed Tomographic Angiography at William Beaumont Hospital (CT DATABASE)
The purpose of the study is to establish an overarching database of information containing historical, demographical, clinical, and intermediate and long-term outcome data from all William Beaumont Hospital (WBH) patients…
- Trial name
- CTDATABASE (NCT00922662)
- Where
- United States
- Volunteers
- 10,000 people
- Sponsor
- Kavitha Chinnaiyan
Acute Otitis Media
Phase 3 Study to Compare the Efficacy and Safety of AR01 to a Placebo Solution for Relief of Pain in Acute Otitis Media
Children ages 2 months to less than 19 years old, who have been diagnosed with a middle ear infection may receive either medicated ear drops (AR01) or glycerin (placebo) ear drops.
- Trial name
- AR01006 (NCT02044341)
- Testing
- AR01, Glycerin ear drops
- Where
- 29 sites in United States
- Volunteers
- 304 people
- Sponsor
- Arbor Pharmaceuticals, Inc.
Peritonitis; Acute, Acute Appendicitis
Retrospective Comparison Between AirSeal® and Standard Insufflation in Appendicular Peritonitis
The AirSeal System Valve-less Trocar is known to decrease postoperative pain, consumption of analgesics, operating time, and length of stay in adults during robotic and laparoscopic procedures.
- Conditions
- Peritonitis; Acute, Acute Appendicitis, Postoperative Pain, Laparoscopy
- Trial name
- APPAS (NCT06734494)
- Testing
- Laparoscopic appendectomy Laparoscopic appendectomy with Airseal or with standard insufflation
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Destinval Christelle
Anesthesia, Consensus Development
Anesthesia Core Quality Metrics Consensus Delphi Study
To develop a ranked list of up to 20 metrics, which can be used to evaluate the quality of anesthesia, perioperative care, and acute pain management for adult inpatient non-cardiac surgical patients for use in quality improvement…
- Trial name
- NCT05386082
- Testing
- Modified Delphi process
- Where
- 3 sites in Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Acute Coronary Syndrome, Acute Chest Pain
Better Evaluation of Acute Chest Pain With Computed Tomography Angiography
The purpose of this study is to determine whether cardiac CT can improve triage of acute chest pain patients in the emergency department.
- Trial name
- BEACON (NCT01413282)
- Testing
- Cardiac CT
- Where
- Netherlands
- Volunteers
- 500 people
- Sponsor
- Erasmus Medical Center
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