Clinical trials: Acute Pain, completed
Virtual Reality, Pain, Acute
Virtual Reality on Pain, Fear, and Emotional Appearance During Phlebotomy in Pediatric Hematology and Oncology Patients
In this study, the effect of virtual reality, which is one of the pain relief methods, on the pain, fear and emotional appearance associated with the procedure, was evaluated in children aged 4-12 years who will undergo…
- Conditions
- Virtual Reality, Pain, Acute, Pediatric Cancer
- Trial name
- VR-PHO (NCT05675358)
- Testing
- Virtual Reality
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 69 people
- Sponsor
- Dokuz Eylul University
Pain, Acute
Tap Block vs Peritoneal Infiltration After Major Gynecological Surgeries
It is a randomized controlled trial to determine the total tramadol consumption after major gynecological studies. Intervention groups include TAP block or local infiltration by the surgeon.
- Trial name
- NCT04037878
- Testing
- Transversus Abdominis Plane Block(TAP Block), Intra-peritoneal infiltration, PCIA Tramadol
- Where
- Pakistan
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Pain, Acute, Fear Anxiety
The Effect of Helfer Skin Tap Technique on Pain, Fear, and Anxiety in Children Undergoing Intramuscular Injection
The aim of this study was to examine the effect of the Helfer Skin Tapping technique on pain, fear, and anxiety in children who received intramuscular injections.
- Conditions
- Pain, Acute, Fear Anxiety, Child, Only, Injection Site
- Trial name
- NCT05250804
- Testing
- Helfer Skin Tap Technique
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Aylin Kurt
Acute Otitis Externa
A Phase III Study of an Otic Formulation in Acute Otitis Externa
The purpose of this study is to determine if an otic formulation is safe and effective for the treatment of acute otitis externa (AOE).
- Trial name
- NCT00750633
- Testing
- Moxidex otic solution, Moxifloxacin otic solution, Dexamethasone phosphate otic solution
- Volunteers
- 990 people
- Sponsor
- Alcon Research
Abdominal Pain
Sublingual Analgesia for Acute Abdominal Pain in Children
Acute abdominal pain is a frequent symptom in children admitted to the emergency department . In the past the fear of masking a surgical condition has justified withholding analgesia in patients with acute abdominal pain.
- Trial name
- NCT02465255
- Testing
- Ketorolac, Tramadol, Acetaminophen
- Where
- Italy
- Volunteers
- 210 people
- Sponsor
- IRCCS Burlo Garofolo
Acute Pain, Neck Pain
Effect of Biofreeze® Versus Placebo on Acute Neck Pain, Disability, and Range of Motion
The purpose of this study to compare the effect of Biofreeze® versus a Placebo on neck pain, disability, fear avoidance, and range of motion prior to and following cervical manipulation over the course of one week among patients…
- Trial name
- NCT03157349
- Testing
- Biofreeze
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- Sport and Spine Rehab Clinical Research Foundation
Hyperalgesia, Pain Response
Interaction Between NGF and Acute Exercise-induced Ischemia
The purpose of this study is to investigate pain evoked responses and facilitation of NGF-induced mechanical muscle hyperalgesia over time following an acute exercised-induced ischemic condition in a NGF-sensitized muscle.
- Conditions
- Hyperalgesia, Pain Response, Healthy Subjects
- Trial name
- NCT03470038
- Testing
- NGF, Isotonic saline
- Where
- Denmark
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Migraine
Efficacy & Safety Of Zomig Nasal Spray For Acute Migraine Treatment In Subjects 6 To 11 Years, With OLE
To evaluate the efficacy and safety of zolmitriptan nasal spray (ZNS) in the acute treatment of migraine headache in subjects ages 6 to 11 years. Part 1: Approximately 20 weeks (includes screening and double-blind treatment).
- Trial name
- NCT03275922
- Testing
- ZNS
- Where
- 47 sites in United States
- Volunteers
- 374 people
- Sponsor
- Impax Laboratories, LLC
Myocardial Injury After Non-cardiac Surgery, Abdomen, Acute
Troponin I Level and Mortality in Acute Abdominal Surgery
The goal of this prospective cohort study is to estimate the incidence of myocardial injury after non-cardiac surgery (MINS) in patients undergoing acute high-risk abdominal surgery.
- Trial name
- NCT05933837
- Testing
- Troponin I
- Where
- Denmark
- Volunteers
- 341 people
- Sponsor
- Nordsjaellands Hospital
Acute Pain
Improving Parental Soothing by Video
This study sets out to compare the effectiveness of a parent pain management coaching video that is 5-minutes in length. The investigators will be comparing an active-video to a placebo-video of equal length (and identical…
- Trial name
- NCT01826383
- Testing
- Active-Video
- Where
- 2 sites in Canada
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- York University
Pain
A Study Comparing Vicodin® CR and NORCO® to Placebo in Subjects With Acute Pain Following Bunionectomy
The purpose of this study is to evaluate the effectiveness (level of pain control) and safety of the administration of Extended Release Hydrocodone/Acetaminophen and Immediate Release Hydrocodone/Acetaminophen with placebo over a…
- Trial name
- NCT00404222
- Testing
- Hydrocodone/Acetaminophen Extended-Release, Hydrocodone/Acetaminophen Immediate Release (NORCO®)
- Volunteers
- 90 people
- Sponsor
- Abbott
Pain
A Study to Evaluate a Fixed Combination of Acetaminophen/Naproxen Sodium in Acute Postoperative Pain Following Bunionectomy
The purpose of this study is to evaluate effectiveness of a fixed combination of acetaminophen/naproxen sodium compared with placebo for reduction of pain when administered as multiple doses over a 48-hour period.
- Trial name
- NCT05868122
- Testing
- Acetaminophen/Naproxen Sodium Fixed Combination
- Where
- 4 sites in United States
- Volunteers
- 143 people
- Sponsor
- Johnson & Johnson Consumer Inc. (J&JCI)
Acute Pain
Intranasal Ketorolac for Postsurgical Pain in Dental Implant Patients
The surgical placement of dental implants is presently a common procedure performed by oral surgeons, periodontists, and general dentists.
- Trial name
- NCT01490931
- Testing
- Ketorolac Nasal Spray
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Hersh, Elliot V., DMD, MS, PhD
Chest Pain
Copeptin and Acute Coronary Syndrome Without ST-segment Elevation
The purpose of this study is to determine whether the combination of copeptine and troponin adds diagnosis information to that provided by troponin alone or the combination of troponin and myoglobin.
- Trial name
- NCT01334645
- Testing
- Copeptin
- Where
- France
- Volunteers
- 134 people
- Sponsor
- University Hospital, Clermont-Ferrand
Pain
Optimal Dose of i.v Oxycodone for Postoperative Pain
Postoperative pain control is required after major abdominal surgery, including laparoscopic colorectal surgery. Intravenous oxycodone is widely used for postoperative acute pain control mainly in Europe.
- Trial name
- NCT02732262
- Testing
- Oxycodone, 1.00 mg dose, Oxycodone, 0.03 mg/kg dose, Oxycodone, 0.02 mg/kg dose
- Where
- South Korea
- Volunteers
- 134 people
- Sponsor
- Seoul National University Hospital
Delirium in the Intensive Care Unit, Sleep Quality in Adult ICU Patients
Virtual Reality to Reduce Anxiety, Agitation and Delirium in Critically Ill Patients
This is a pilot feasibility study examining the use of immersive virtual reality (VR) in adult intensive care unit (ICU) patients.
- Conditions
- Delirium in the Intensive Care Unit, Sleep Quality in Adult ICU Patients, Agitation Associated With Critical Illness, Anxiety Acute
- Trial name
- NCT07649876
- Testing
- Virtual reality (VR) therapy
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Low Back Pain
Lumbar Manipulation and Exercise for the Treatment of Acute Low Back Pain in Adolescents
The purpose of this study is to determine if the addition of lumbar manipulation will improve function, decrease pain, and recurrence in adolescents with low back pain.
- Trial name
- NCT02111278
- Testing
- Lumbar Manipulation, Physical Therapy
- Where
- 3 sites in United States
- Volunteers
- 35 people
- Sponsor
- Nationwide Children's Hospital
Asthma Attack, Asthma in Children
The Effect of Nebulization Positions in Asthmatic Children
The purpose of this study was to establish the effect on pulse rate, oxygen saturation, respiratory rate, pain and anxiety levels of Fowler's and the forward-leaning positions during nebulization in children experiencing asthma…
- Conditions
- Asthma Attack, Asthma in Children, Asthma Acute, Asthma
- Trial name
- NCT05318885
- Testing
- A Randomized Controlled Study
- Where
- Turkey (Türkiye)
- Volunteers
- 86 people
- Sponsor
- Istanbul University - Cerrahpasa
Pain, Acute, Anesthesia
Pupillary Dilation Reflex Assessment for Intraoperative Analgesic Titration.
In this double blinded randomized controlled study, the pupillary dilation reflex is used for as a nociceptive indicator for opioid administration during elective surgery under general anesthesia.
- Trial name
- PUP-AIT (NCT03248908)
- Testing
- Pupillary dilation reflex, Standard of care
- Where
- Belgium
- Volunteers
- 120 people
- Sponsor
- University Hospital, Antwerp
Acute Pain
OMT vs. Standard Therapy in the Management of Acute Neck and Low Back Pain in the Emergency Department
Patients 18 to 65 years old who present within 72 hours of onset pain will be considered for study enrollment. Patients with the acute musculoskeletal low back or neck pain based on ED history and structural physical exam will be…
- Trial name
- NCT06987578
- Testing
- OMT vs. Ibruprofen
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- St. Joseph's Regional Medical Center, New Jersey
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