Clinical trials: Acute Pain Management
Cardiology, Acute Coronary Syndrome
Echocardiography by Non-cardiologist in Early Management of Patients With Chest Pain
The aim of the study is to find out the benefit of echocardiography, which is performed by a physican without a cardiological or radiological specialty.
- Conditions
- Cardiology, Acute Coronary Syndrome, Echocardiography
- Trial name
- ENDEMIC (NCT05306730)
- Testing
- ECHOcardiography, Point-of-Care UZ
- Volunteers
- 430 people
- Sponsor
- University of Defence, Faculty of Military Health Sciences
Pain, Acute
Comparison of Low-dose Ketamine to Opioids in the Management of Acute Pain in Patients Presenting to the Emergency Department With Long Bone Fractures
The purpose of this study is to establish the feasibility of initiating a ketamine pain control protocol in the emergency department for the treatment of acute pain in patients with long bone fractures and to compare the efficacy…
- Trial name
- NCT04061330
- Testing
- Ketamine, Morphine
- Where
- United States
- Sponsor
- The University of Texas Health Science Center, Houston
Trauma, Acute Pain
Magnesium Infusion for Pain Management in Critically Ill Trauma Patients
Magnesium is a naturally occurring mineral that is important for your body and brain. Magnesium sulfate (study drug) is a medication containing magnesium that is commonly used to improve low blood levels of magnesium.
- Trial name
- NCT04166877
- Testing
- Magnesium Sulfate in Parenteral Dosage Form
- Where
- United States
- Volunteers
- 156 people
- Sponsor
- University of California, Davis
Sickle Cell Disease (SCD), Sickle Cell Disease Vaso-occlusive Crisis
Buprenorphine for the Management of Pain in Children With Sickle Cell Disease
The goal of this clinical trial is to learn whether a single dose of buccal buprenorphine (BELBUCA) is safe when used in place and/or with full agonist opioids that would otherwise be started during a sickle cell pain crisis…
- Conditions
- Sickle Cell Disease (SCD), Sickle Cell Disease Vaso-occlusive Crisis, Sickle Cell Anemia Crisis, Sickle Cell Anemia in Children
- Trial name
- NCT07799571
- Testing
- Buprenorphine Buccal Film [Belbuca]
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Natasha Archer
Rib Fractures, Rib Trauma
PVB vs Ketamine/Lidocaine in Rib Fracture Patients
Rib fractures are a common admission to the trauma service. The mainstay of treatment is pain control to improve respiratory effort in order to offset the risk of pneumonia and mechanical ventilation.
- Conditions
- Rib Fractures, Rib Trauma, Rib Fracture Multiple, Pain, Acute
- Trial name
- NCT04413799
- Testing
- lidocaine, ketamine intravenous infusion, paravertebral block with ropivicaine
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- George Washington University
Knee Disease, Arthritis Knee
Intraosseous Morphine in Primary TKA
The research team wants to investigate if an intraosseous injection (directly into the bone marrow) of morphine during primary total knee replacement helps with post-operative pain following primary total knee replacement…
- Conditions
- Knee Disease, Arthritis Knee, Pain, Acute
- Trial name
- NCT04388111
- Testing
- Morphine
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- The Methodist Hospital Research Institute
Analgesia, Pain, Acute
Duration of Analgesia With Dexmedetomidine and Ropivacaine in Brachial Plexus Block
This is a prospective, randomized, double blind study of adding dexmedetomidine to ropivacaine for Brachial plexus block and assessing the analgesia with VAS pain scales(0-10), Satisfaction scale by VAS scale(0-10) and time to…
- Conditions
- Analgesia, Pain, Acute, Peripheral Nerve Block
- Trial name
- NCT03385967
- Testing
- Dexmedetomidine, ropivacaine
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Florida
Pain, Acute, Trauma Injury
Use of Penthrox in Extra-hospital Traumatology
In pre-hospital settings, the administration of analgesics is often delayed because of difficult patient access (incarceration), difficulty finding a venous pathway or patient refusal.
- Conditions
- Pain, Acute, Trauma Injury, Pain Management
- Trial name
- UPETEH (NCT03537001)
- Testing
- Penthrox
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Tours
Pain, Postoperative
Scheduled or as Needed Pain Regimen?
The aim of this study is to determine feasibility of a randomized controlled trial and estimates of efficacy for pain control of a scheduled pain regimen versus an as needed pain regimen for participants undergoing same day…
- Trial name
- NCT06495632
- Testing
- Motrin and narcotic
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Cape Fear Valley Health System
Acute Pain, Anxiety
MOLI Technique and Virtual Reality Versus Conventional Venipuncture for Pain and Anxiety in Children
Venipuncture is one of the most frequent and distressing invasive procedures in paediatric care. Both immersive virtual reality (VR) and structured breathing-based active distraction have been proposed as effective…
- Conditions
- Acute Pain, Anxiety, Pain, Procedural, Phlebotomy
- Trial name
- MOLIVeR (NCT07878117)
- Testing
- Conventional venipuncture technique, MOLI technique, Meta Quest 3 with Fruit Ninja VR
- Where
- Spain
- Volunteers
- 201 people
- Sponsor
- José Luis Cobo Sánchez
Acute Pain Due to Trauma
Sublingual Versus Endovenous Fentanyl for Pain Treatment in Trauma Patients in the Emergency Room
The purpose of this study is to determine the non-inferiority of the efficacy of sublingual given fentanyl versus endovenous given fentanyl for patients in the emergency departement.
- Trial name
- NCT03080324
- Testing
- Fentanyl sublingual, Fentanyl ev
- Where
- Italy
- Volunteers
- 108 people
- Sponsor
- Azienda Sanitaria dell'Alto Adige
Postoperative Pain, Analgesia
Perioperative Multimodal Analgesia Protocol for Supratentorial Craniotomy
Supratentorial craniotomy is one of the most common neurosurgical procedures, with severe perioperative pain. Inadequate perioperative pain relief has been associated with increased blood pressure and intracranial pressure…
- Conditions
- Postoperative Pain, Analgesia, Supratentorial Brain Tumor
- Trial name
- NCT06406829
- Testing
- Dexmedetomidine, Normal saline, Local analgesic techniques
- Volunteers
- 2,000 people
- Sponsor
- Beijing Tiantan Hospital
Lower Abdominal Pain, Right Iliac Fossa Pain
Non Operative Treatment for Acute Appendicitis
Case control studies that randomly assign patients to either surgical or non-surgical treatment yield a relapse rate of approximately 14% at one year.
- Conditions
- Lower Abdominal Pain, Right Iliac Fossa Pain, Acute Appendicitis
- Trial name
- NOTA (NCT01096927)
- Testing
- Amoxicillin and Clavulanic Acid
- Where
- Italy
- Volunteers
- 160 people
- Sponsor
- Maggiore Bellaria Hospital, Bologna
Urodynamics, Acute Urinary Retention
Effects of Thoracic Epidural Anesthesia on Lower Urinary Tract Function
Acute urinary retention is one of the most common complications after surgery and anesthesia. Overfilling the bladder can stretch and damage the detrusor muscle, leading to atony of the bladder.
- Trial name
- NCT00790231
- Testing
- urodynamic procedure
- Where
- Switzerland
- Volunteers
- 32 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Breast Cancer, Acute Postoperative Pain
Combined PECS II and Transversus Plane Blocks Versus Erector Spinae Block in Modified Radical Mastectomy
The aim of this study is to compare the total morphine consumption in the first 24 hour postoperative between combined modified pectoralis block (PECS II) and transversus plane block versus erector spinae block in modified…
- Trial name
- NCT03903224
- Testing
- Combined Modified Pectoralis and Transversus Plane Blocks, Erector Spinae block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Total Abdominal Hysterectomy ,Pain , Acute Postoperative,Gabapentin , Celecoxib
Preoperative Analgesia in Non-gynecological Cancerous Women Who Underwent Elective Total Abdominal Hysterectomy
Comparison of effectiveness of preoperative Gabapentin with Celecoxib in reducing acute postoperative pain in abdominal hysterectomy, A randomized double blind controlled trial
- Trial name
- NCT03672162
- Testing
- Total abdominal hysterectomy
- Where
- Thailand
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand
Cardiovascular Surgical Procedures, Pain, Postoperative
Fascial Plane Blocks and Quality of Recovery in Cardiac Surgery
In this randomized trial, the investigators will test the hypothesis that combining regional analgesia techniques-which have the potential to improve the quality of postoperative recovery following median sternotomy-with PIFB…
- Conditions
- Cardiovascular Surgical Procedures, Pain, Postoperative, Cardiovascular Diseases
- Trial name
- NCT07557108
- Testing
- Ultrasound-Guided Pectointercostal Fascial Plane Block, Ultrasound-Guided Rectus Sheath Block, Ultrasound-Guided Recto-Intercostal Fascial Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 123 people
- Sponsor
- Ordu University
Labor Pain, Pain, Postoperative
Spinal Analgesia as Fast Track Painless Labor
The purpose of this prospective, randomized, and controlled trial was to compare the efficacy of single-shot spinal analgesia to typical conventional treatments (continuous epidural analgesia and spinal-epidural combination) in…
- Conditions
- Labor Pain, Pain, Postoperative, Pain, Acute
- Trial name
- NCT05271760
- Testing
- Single-shot spinal analgesia, Continuous epidural analgesia, Combined spinal-epidural analgesia
- Where
- Saudi Arabia
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Prince Sattam Bin Abdulaziz University
Pain, Postoperative
Reducing Opioid Use and Misuse After Wisdom Molar Extractions
Reducing opioid prescription related use and misuse is a major focus for countering the national epidemic of opioid overdose and death.
- Trial name
- NCT04414917
- Testing
- Twin block, iPill dispenser
- Where
- United States
- Volunteers
- 133 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Elderly, Older Adults
The PAINFREE Initiative, a Stepped Wedge Cluster Randomized Trial
The PAINFREE (Improving PAIN control following FRactures; towards an Elder-friendly Emergency department) Initiative is a patient-centered multifaceted intervention which aims to improve pain management in patients 75 years and…
- Conditions
- Elderly, Older Adults, Bone Fracture, Emergency Department
- Trial name
- PAINFREE (NCT03082417)
- Testing
- Implementation
- Where
- Canada
- Volunteers
- 1,375 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre