Clinical trials: Acute Pancreatitis
Acute Pancreatitis
Use of Patient-Controlled Analgesia in Acute Pancreatitis
Acute pancreatitis (AP) represents a critical health concern nationwide, with estimated 274,000 admissions annually and at a cost of 2.6 billion dollars.
- Trial name
- PCA-AP (NCT04816877)
- Testing
- Opioid
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Beth Israel Deaconess Medical Center
Pancreatitis Relapsing
Simvastatin in the Prevention of Recurrent Pancreatitis
Recurrent acute pancreatitis and recurrent relapses of inflammation in chronic pancreatitis are an important problem. In some cases, prevention of these acute flares of inflammation is not possible.
- Trial name
- SIMBA-16 (NCT04021498)
- Testing
- Simvastatin 40mg
- Where
- Spain
- Volunteers
- 83 people
- Sponsor
- Enrique de-Madaria
Acute Pancreatitis, Complication
Rectal Indomethacin as Early Treatment for Acute Pancreatitis (INDOMAP Trial)
Acute pancreatitis (AP) is an inflammatory condition of the pancreas following the activated pancreatic enzymes induced by varied causes, with or without other organ(s) dysfunction.
- Conditions
- Acute Pancreatitis, Complication, Mortality Rate, Organ Failure, Multiple
- Trial name
- INDOMAP (NCT03547232)
- Testing
- Indomethacin SR
- Where
- 17 sites in China
- Volunteers
- 1,504 people
- Sponsor
- Peking Union Medical College Hospital
Acute Pancreatitis, Acute Pancreatic Necrosis
coMpliAnce With evideNce-based cliniCal Guidelines in the managemenT of Acute biliaRy pancreAtitis
Acute pancreatitis (AP) is an inflammatory disease of the pancreas, most commonly caused by gallstones, or excessive use of alcohol. It represents a management challenge and a significant healthcare burden.
- Conditions
- Acute Pancreatitis, Acute Pancreatic Necrosis, Acute Pancreatitis Due to Gallstones, Acute Pancreatic Fluid Collection
- Trial name
- MANCTRA-1 (NCT04747990)
- Testing
- Early Definitive Treatment
- Where
- 3 sites in Italy, Spain
- Volunteers
- 600 people
- Sponsor
- University of Cagliari
Pancreatitis, Acute
A Long-term Safety Follow-up Study of SCM-AGH in Patients Who Completed SCM-APT2001 Study
This is a long-term safety follow-up study of the Phase I/IIa multicenter study of SCM-AGH in subjects with moderate to severe acute pancreatitis.
- Trial name
- NCT05955235
- Testing
- Not Applicable(Observation Study)
- Where
- 6 sites in South Korea
- Volunteers
- 42 people
- Sponsor
- SCM Lifescience Co., LTD.
Acute Pancreatitis
Neutrophil/Lymphocyte Ratio in Acute Pancreatitis
Acute pancreatitis (AP) is a disease characterized by dysfunction of pancreatic acinar cells, improper activation of trypsin, and subsequent destruction of pancreatic self-defense mechanisms, further exacerbating injury and…
- Trial name
- NCT05859633
- Testing
- Neutrophil/Lymphocyte Ratio in acute pancreatitis
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University
Acute Pancreatitis (AP), Hypertriglyceridemia Acute Pancreatitis
Multicenter Prospective Cohort Study of Hypertriglyceridemia Acute Pancreatitis
Hypertriglyceridemia-associated acute pancreatitis (HTG-AP) is the second leading cause in China and is receiving increasing global attention.
- Trial name
- NCT06976099
- Where
- 12 sites in China
- Volunteers
- 1,000 people
- Sponsor
- Peking Union Medical College Hospital
Pancreatitis
Acute Pancreatitis: Study of Possible Etiologies and Risk Factors Affecting Outcome
This study is to assess the frequency of different etiologies of acute pancreatitis in our locality \& assess the effect of different risk factors on outcome of the patients.
- Trial name
- NCT03601325
- Where
- Egypt
- Volunteers
- 300 people
- Sponsor
- Assiut University
Acute Pancreatitis, Pancreatic Pseudocyst
Registry of Patients Undergoing Endoscopic Management of Pancreatic Fluid Collections
Acute pancreatitis is one of the most common gastrointestinal disorders requiring hospitalization worldwide. Pancreatic fluid collections can occur as a consequence of acute and chronic pancreatitis and can result in significant…
- Conditions
- Acute Pancreatitis, Pancreatic Pseudocyst, Pancreatic Necrosis
- Trial name
- NCT06179459
- Testing
- Endoscopic management of pancreatic fluid collections
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Orlando Health, Inc.
Acute Pancreatitis
Thoracic Ultrasound on Acute Pancreatitis
Authors design a prospective, longitudinal, descriptive study to identify the findings of thoracic point-of-care ultrasound in patients with acute pancreatitis.
- Trial name
- ECOPANC (NCT04033549)
- Where
- Mexico
- Volunteers
- 49 people
- Sponsor
- Hospital Universitario Dr. Jose E. Gonzalez
Cholecystectomy, Gallbladder
EUS-Guided Gallbladder Drainage Versus Conservative Management in Patients Unfit for Surgery After a Biliary Event Without Cholecystitis. DRECON Study
Cholecystectomy is considered the standard definitive treatment after an acute biliary event (biliary colic, acute pancreatitis, cholangitis, or choledocholithiasis).
- Conditions
- Cholecystectomy, Gallbladder, Endoscopic Ultrasound (EUS), Cholelithiasis
- Trial name
- DRECON (NCT07655778)
- Testing
- EUS-guided gallbladder drainage (EUS-GBD), Conservative management (CM)
- Volunteers
- 110 people
- Sponsor
- Hospital Mutua de Terrassa
Acute Pancreatitis
Enhanced Recovery in Acute Pancreatitis
Prospective randomized-controlled trial evaluating impact of enhanced recovery protocol compared to standard care for recovery of patients with acute pancreatitis.
- Trial name
- ASERT (NCT02813876)
- Testing
- Enhanced recovery protocol
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Kaiser Permanente
Acute Pancreatitis, Artificial Intelligence
Artificial Intelligence Prediction for the Severity of Acute Pancreatitis
The incidence of acute pancreatitis (AP) is increasing nowadays. The diagnosis of AP is defined according to Atlanta criteria with the presence of two of the following 3 findings; a) characteristic abdominal pain b) amylase and…
- Conditions
- Acute Pancreatitis, Artificial Intelligence, Outcome, Fatal
- Trial name
- NCT04735055
- Where
- Turkey (Türkiye)
- Volunteers
- 1,334 people
- Sponsor
- Bezmialem Vakif University
Acute Pancreatitis
Prophylactic Tributyrin Supplementation in Acute Pancreatitis
The goal of this clinical trial is to investigate the possible effects of tributyrin supplementation in patients with a first episode of acute pancreatitis.
- Trial name
- PARROT (NCT06147635)
- Testing
- Micro-encapsulated granules of tributyrin (intervention)
- Where
- 2 sites in Netherlands
- Volunteers
- 92 people
- Sponsor
- St. Antonius Hospital
Recurrent Acute Pancreatitis
ERCP in Idiopathic Recurrent Acute Pancreatitis
The therapeutic impact of ERCP with sphincterotomy in the management of patients with idiopathic recurrent acute pancreatitis (RAP) needs further study.
- Trial name
- NCT01583517
- Testing
- Biliary sphincterotomy, Pancreatobiliary sphincterotomy
- Where
- United States
- Volunteers
- 89 people
- Sponsor
- Indiana University
Acute Pancreatitis, Obesity
The Course of Acute Pancreatitis in Patients With Different BMI Groups
In obese (OB) patients, the presence of an increased inflammatory state in the body due to the increase in abdominal adipose tissue and increase in the frequency of gallstones and lipid levels are expected to increase the…
- Conditions
- Acute Pancreatitis, Obesity, Body Weight
- Trial name
- NCT04901949
- Where
- Turkey (Türkiye)
- Volunteers
- 1,334 people
- Sponsor
- Bezmialem Vakif University
Pancreatitis
Phosphate in Acute Pancreatitis
The goal of this study is to learn if phosphate administration works to treat acute pancreatitis in adults presenting to the emergency department at Duke University Hospital.
- Trial name
- PPP (NCT07681050)
- Testing
- Sodium Phosphate, Potassium Phosphate
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Duke University
Severe Acute Pancreatitis Patients
Early Rehabilitation for Severe Acute Pancreatitis (ERN-SAP)
This prospective, randomized controlled trial investigates the efficacy of a structured early rehabilitation nursing (ERN) program compared to usual care in patients with severe acute pancreatitis (SAP).
- Trial name
- NCT07109921
- Testing
- Structured Early Rehabilitation Nursing Program, Usual Care
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Sixth Hospital of Wuhan, Affiliated Hospital of Jianghan University
Acute Pancreatitis
Evaluation of Intravenous Fluid Therapy Within Dallas Acute Pancreatitis Protocol
Acute pancreatitis (AP) is a common disease of the gastrointestinal tract that can result in emotional, physical, and financial burdens on the patient.
- Trial name
- NCT06223594
- Testing
- Intravenous Fluid Therapy
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Methodist Health System
Acute Gallstone Pancreatitis
The Effect of Gallstone Characteristics for the Severity of Gallstone Pancreatitis
The purpose of this study was to determine the effect of gallstone characteristics for the severity of acute gallstone pancreatitis (GSP)
- Trial name
- NCT05498961
- Testing
- Gallstone characteristics
- Where
- China
- Volunteers
- 301 people
- Sponsor
- Hepatopancreatobiliary Surgery Institute of Gansu Province