Clinical trials: Acute Pancreatitis (AP), open to volunteers
Acute Pancreatitis (AP)
Endoscopic Pancreatic Duct Stent Placement Versus Conventional Approach in the Treatment of Early Phase Acute Pancreatitis
The planned multicenter randomized study is aimed to assess the efficacy and safety of endoscopic pancreatic duct stenting in adult patients with acute pancreatitis.
- Trial name
- NCT07093996
- Testing
- Endoscopic pancreatic duct stent placement, Conventional treatment of acute pancreatitis in early phase
- Where
- 7 sites in China, Russia
- Volunteers
- 200 people
- Sponsor
- Almazov National Medical Research Centre
Organ Dysfunction, Organ Support
Thoracic Epidural Analgesia for Acute Pancreatitis With Early Organ Dysfunction
Acute pancreatitis may cause early respiratory, cardiovascular, or renal dysfunction and may require intensive care and organ support.
- Conditions
- Organ Dysfunction, Organ Support, Acute Pancreatitis (AP)
- Trial name
- TEA-APOD (NCT07697690)
- Testing
- Thoracic Epidural Analgesia With Ropivacaine, conventional analgesia
- Volunteers
- 150 people
- Sponsor
- First People's Hospital of Chenzhou
Acute Pancreatitis (AP), Thrombotic Disorders
Retrospective Analysis of Acute Pancreatitis After Percutaneous Mechanical Thrombectomy In Treatment Of Thrombotic Disorders
Acute pancreatitis is a rare complication after percutaneous mechanical thrombectomy in treatment of thrombotic disorders. The objectives of this study include: (1) Determine the incidence and severity of acute pancreatitis after…
- Trial name
- NCT07450898
- Where
- China
- Volunteers
- 10 people
- Sponsor
- RenJi Hospital
Acute Pancreatitis (AP), Acute Pancreatitis With Infected Necrosis
Comparison of MIPPED-C and Surgical Necrosectomy in Pancreatic Necrosis Outcomes
This study is a retrospective, single-center, pre-post controlled clinical study. Patients (n=48) who underwent the MIPPED-C surgical procedure after January 1, 2019 were designated as the treatment group.
- Trial name
- NCT07097753
- Where
- China
- Volunteers
- 144 people
- Sponsor
- Ruijin Hospital
Acute Pancreatitis (AP)
Stroke Volume-based Fluid Resuscitation in AP
The SUSTAIN Trial is a randomized control trial that allows for the control of aggressive hydration that is currently used in an inpatient setting, which can result is fluid overload in certain patients.
- Trial name
- SUSTAIN (NCT07756476)
- Testing
- Lactated Ringer's, Lactated Ringers Stroke Volume Based Dosing
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- University of Southern California
Acute Pancreatitis (AP), Severe Acute Pancreatitis
Bowel Sound in Predicting the Severity of Acute Pancreatitis: Protocol of a Prospective, Multi-center Study
Introduction: Acute pancreatitis (AP) is a common condition, with 20% of cases progressing to severe acute pancreatitis (SAP), which is associated with a poor prognosis.
- Trial name
- NCT06867120
- Where
- China
- Volunteers
- 352 people
- Sponsor
- Peking Union Medical College Hospital
Pancreatitis, Chronic Pancreatitis
Varenicline for Smoking Cessation in Pancreatitis
This study will look at how safe and how effective varenicline, a commonly used medication for smoking cessation, is in helping patients with pancreatitis stop smoking cigarettes.
- Conditions
- Pancreatitis, Chronic Pancreatitis, Acute Pancreatitis (AP), Recurrent Acute Pancreatitis
- Trial name
- NCT07874841
- Testing
- Varenicline (VAR)
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Mayo Clinic
Acute Pancreatitis (AP), Inflammatory Indices
Utilization of CBC-Derived Inflammatory Indices in Assessing Severity and Prognosis of Acute Pancreatitis.
Utilization of CBC-Derived Inflammatory Indices in Assessing Severity and Prognosis of Acute Pancreatitis.
- Trial name
- NCT07233551
- Testing
- CBC derived inflammatory indices
- Volunteers
- 100 people
- Sponsor
- Assiut University
Pancreatic Cancer, Diagnose Disease
AI-Powered Precision Decision-Making for Pancreatic Diseases
This multicenter clinical trial evaluates an artificial intelligence (AI) system designed to assist in the diagnosis and management of pancreatic diseases.
- Conditions
- Pancreatic Cancer, Diagnose Disease, IPMN, Pancreatic, Pancreatic Cystic Lesions
- Trial name
- NCT07439757
- Testing
- Diagnosis by Artificial Intelligence model
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Changhai Hospital
Acute Pancreatitis (AP), Enhancing Enteral Nutrition Tolerance
Evaluating RELiZORB Use for the Treatment of Feeding Intolerance in Adults With Moderate to Severe Acute Pancreatitis
The goal of this study is to learn if Relizorb, a fat-digesting enzyme, can improve tolerance of tube feeds in adult patients with moderate to severe pancreatitis.
- Trial name
- NCT07583342
- Testing
- RELiZORB digestive enzyme (immobilized lipase) cartridge
- Where
- 5 sites in United States
- Volunteers
- 15 people
- Sponsor
- Northwell Health
Acute Pancreatitis (AP), Acute Pancreatic Fluid Collection
Dextran 40 Plus Ringer's Lactate Vs. Ringer's Lactate Alone for Fluid Resuscitation in Acute Pancreatitis
This clinical trial aims to learn if a combination of Dextran 40 and Ringer's lactate solution can improve fluid resuscitation in mild and moderate acute pancreatitis (AP) and prevent complications.
- Conditions
- Acute Pancreatitis (AP), Acute Pancreatic Fluid Collection, Fluid Resuscitation
- Trial name
- NCT06835023
- Testing
- Ringer lactate (RLS), Dextran+Ringer Lactat(D+RLS)
- Where
- Romania
- Volunteers
- 100 people
- Sponsor
- Satu Mare County Emergency Hospital
Acute Pancreatitis (AP)
Heparin to Prevent Organ Failure in Acute Pancreatitis
This clinical trial is designed to evaluate whether adding a standard blood-thinning medication, Unfractionated Heparin, to standard hospital care can help prevent severe organ failure in patients admitted with acute…
- Trial name
- NCT07609771
- Testing
- Unfractionated heparin, Standard supportive care
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Allied Hospital Faisalabad
Acute Pancreatitis (AP)
A Trial of the Arctx Cool Catheter in Acute Pancreatitis
Researchers will compare people who get the ACC Set plus standard of care to people who get standard of care alone. This will show whether adding the ACC Set helps.
- Trial name
- CHILL-AP (NCT07698119)
- Testing
- Treatment, Control
- Volunteers
- 200 people
- Sponsor
- Arctx Medical, Inc.
Acute Pancreatitis (AP)
ENDoscopic Assessment in Acute PANcreatitis Study (ENDOPAN Study)
This is a prospective observational cohort study designed to evaluate early upper gastrointestinal endoscopic findings in adult patients hospitalized with acute pancreatitis.
- Trial name
- NCT07714850
- Where
- Poland
- Volunteers
- 200 people
- Sponsor
- Jan Kochanowski University
Acute Pancreatitis
iMmune SignAtures and Clinical outComes in AP
The MoSAIC study is a prospective, observational study designed to develop an early prediction tool for severe acute pancreatitis (SAP) and define a distinct immunologic profile compared to moderate acute pancreatitis (MAP).
- Trial name
- MoSAIC (NCT05878236)
- Testing
- CyTOF Analysis
- Where
- 5 sites in United States
- Volunteers
- 198 people
- Sponsor
- Ohio State University
Acute Pancreatitis (AP), Hypertriglyceridemia Acute Pancreatitis
Multicenter Prospective Cohort Study of Hypertriglyceridemia Acute Pancreatitis
Hypertriglyceridemia-associated acute pancreatitis (HTG-AP) is the second leading cause in China and is receiving increasing global attention.
- Trial name
- NCT06976099
- Where
- 12 sites in China
- Volunteers
- 1,000 people
- Sponsor
- Peking Union Medical College Hospital
Exocrine Pancreatic Insufficiency
Pancreatic Enzyme Replacement Therapy for Acute Pancreatitis-Associated Exocrine Pancreatic Insufficiency
This study aims to evaluate if a 6-month course of pancrelipase (CREON) treatment improves symptoms of exocrine pancreatic insufficiency (EPI) after an attack of acute pancreatitis.
- Trial name
- PERT-AP (NCT06477159)
- Testing
- Pancrelipase Capsules
- Where
- 6 sites in United States
- Volunteers
- 30 people
- Sponsor
- Ohio State University
Walled Off Pancreatic Necrosis, Acute Pancreatitis (AP)
Nasojejunal Feeding Versus Oral Feeding Following Endoscopic Drainage of Walled Off Pancreatic Necrosis
The goal of this randomized control trial is to assess whether nasojejunal feed is better than oral nutrition in patients who are undergoing endoscopic cystogastrostomy of walled off necrosis following acute pancreatitis.
- Conditions
- Walled Off Pancreatic Necrosis, Acute Pancreatitis (AP), Endoscopic Ultrasound-Guided Drainage
- Trial name
- NCT07395778
- Testing
- endoscopic ultrasonography guided cystogastrostomy
- Where
- India
- Volunteers
- 50 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Acute Pancreatitis Necrotizing, Nutrition Assessment
PERT in Acute Necrotizing Pancreatitis
In this multicenter, double blinded, placebo-controlled, 1:1 parallel group RCT, we propose to evaluate the impact of pancreatic exocrine replacement therapy on patients with acute necrotizing pancreatitis (ANP).
- Trial name
- PERT-ANP (NCT07211568)
- Testing
- Pancreatic Enzyme Replacement Therapy
- Volunteers
- 188 people
- Sponsor
- Asian Institute of Gastroenterology, India
Post ERCP Pancreatitis, Acute Pancreatitis (AP)
Cold Water Papillary Irrigation Plus Rectal NSAIDs vs Rectal NSAIDs Alone for Post-ERCP Pancreatitis (COLD)
Post-ERCP pancreatitis is the most frequent complication of endoscopic retrograde cholangiopancreatography (ERCP). Rectal non-steroidal anti-inflammatory drugs (NSAIDs) are the current standard prophylaxis.
- Trial name
- COLDHUVN (NCT07885852)
- Testing
- Cold water irrigation of the papilla, Rectal NSAID (diclofenac 100 mg)
- Where
- Spain
- Volunteers
- 250 people
- Sponsor
- University Hospital Virgen de las Nieves