Clinical trials: Acute Peritonitis
Appendicolith, Appendicitis
Laparoscopic Appendectomy Performed by Junior SUrgeonS: Impact of 3D Visualization on Surgical Outcome
Laparoscopy has revolutionized the approach to a number of surgical problems causing a re-evaluation of several clinical strategies.
- Conditions
- Appendicolith, Appendicitis, Appendicitis With Perforation, Appendicitis Peritonitis
- Trial name
- LAPSUS (NCT03770897)
- Testing
- 3D Laparoscopic Appendectomy, 2D Laparoscopic Appendectomy
- Where
- Italy
- Volunteers
- 128 people
- Sponsor
- Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
Acute Peritonitis, Abdominal Sepsis
Physiologic Indicators for Prognosis in Abdominal Sepsis Study
Early detection and timely therapeutic intervention can improve the prognosis of patients with sepsis. However, early diagnosis of sepsis can be difficult; because determining which patients presenting with signs of infection…
- Trial name
- PIPAS (NCT03408600)
- Testing
- Management
- Where
- Italy
- Volunteers
- 4,000 people
- Sponsor
- World Society of Emergency Surgery
Appendicitis Acute, Appendicitis
Safety & Feasibility of PERIsign System in Demonstrating Involuntary Muscle Defense as a Sign of Peritonitis in Subjects With Appendicitis
This will be an explorative, proof-of-principle, open, multi-center investigation. The investigation aims to investigate the safety of the PERIsign system and the ability of physicians to differentiate between healthy individuals…
- Conditions
- Appendicitis Acute, Appendicitis, Abdominal Pain, Peritonitis
- Trial name
- PeriSaFe01 (NCT06296953)
- Testing
- PERIsign examination
- Where
- 2 sites in Sweden
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- STB INN AB
Acute Abdomen, Bowel Obstruction
The Best Care for Abdominal Emergencies Study
This is a single-centre retrospective cohort study utilising electronic hospital records. The aim of this study is to improve care for all patients with an intestinal emergency, irrespective of whether they have surgery or not.
- Conditions
- Acute Abdomen, Bowel Obstruction, Bowel; Ischemic, Acute, Bowel Perforated
- Trial name
- BCAE (NCT04577339)
- Testing
- Laparotomy or laparoscopy
- Where
- United Kingdom
- Volunteers
- 2,500 people
- Sponsor
- Portsmouth Hospitals NHS Trust
Acute Kidney Injury, Peritonitis
Phase 3 Study of Reltecimod vs Placebo in Patients With Sepsis-associated Acute Kidney Injury
Phase 3 multicenter study to be conducted in up to 90 qualified participating sites globally to assess the efficacy and safety of Reltecimod vs placebo in patients with sepsis-associated Stage 2/3 AKI.
- Conditions
- Acute Kidney Injury, Peritonitis, Necrotizing Soft Tissue Infection
- Trial name
- NCT03403751
- Testing
- Reltecimod 0.5 mg/kg
- Where
- 56 sites in United States, France
- Volunteers
- 58 people
- Sponsor
- Atox Bio Ltd
Peritonitis
Clinical Relevance of the Reverse Lipopolysaccharide Transport Pathway in Patients With Acute Peritonitis
When there is infection in the intra-abdominal area, bacteria secrete toxins that are absorbed by the peritoneum. These toxins then bind to lipoproteins (which carry cholesterol in the blood) and are eliminated by the liver.
- Trial name
- LIPS (NCT04126577)
- Testing
- blood samples
- Where
- France
- Volunteers
- 27 people
- Sponsor
- Centre Hospitalier Universitaire Dijon