Clinical trials: Acute Physical Exercise
Chronic Obstructive Pulmonary Disease
Smart Telehealth Exercise Intervention to Reduce COPD Readmissions
This is a prospective randomized controlled study to test the hypothesis that neuromuscular electrical stimulation (NMES) and remote pulmonary rehabilitation at home offered via a smart technology, called Smart TeleHealth…
- Trial name
- NCT03089853
- Testing
- Neuromuscular electrical stimulation (NMES)
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University of Alabama at Birmingham
Hypertension, Pulmonary, Altitude Sickness
Efficacy Study of Riociguat and Its Effects on Exercise Performance and Pulmonary Artery Pressure at High Altitude
During ascent to high altitude there is a physiologic response to hypoxia that results in an elevated pulmonary arterial pressure associated with decreased exercise performance, altitude-induced pulmonary hypertension, and high…
- Trial name
- NCT02024386
- Testing
- Riociguat
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Richard Moon
Glucose Metabolism, High Altitude
High Altitude and Exogenous Carbohydrate Oxidation
Recent studies have reported that oxidation of exogenous carbohydrate is reduced under acute hypobaric hypoxic (high altitude; HA) conditions compared to normoxia (sea level; SL) in native lowlanders.
- Trial name
- NCT03851744
- Testing
- Sea Level, High Altitude
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- United States Army Research Institute of Environmental Medicine
B Precursor Type Acute Leukemia
Improving Diet and Exercise in Acute Lymphoblastic Leukemia (IDEAL Weight in ALL)
This study tests the ability of a focused dietary, exercise, and activity intervention to reduce fat gain during induction therapy for childhood acute lymphoblastic leukemia to improve disease response and reduce toxicity.
- Trial name
- NCT02708108
- Testing
- Dietary Intervention, Activity and Exercise Intervention
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Children's Hospital Los Angeles
Acute Deep Vein Thrombosis
Role of a Novel Exercise Program to Prevent Post-thrombotic Syndrome
Despite standard care, 25%-50% of patients with clots in the deep veins of the arms and legs progress to chronic post-clot problems resulting in significant disability, loss of productivity, and healthcare costs.
- Trial name
- EFFORT2 (NCT02148029)
- Testing
- Exercise, Standard Care
- Where
- United States
- Volunteers
- 107 people
- Sponsor
- VA Office of Research and Development
Acute Myeloid Leukemia
Acute Myeloid Leukaemia (AML) Patients Undergoing Induction Chemotherapy
Fatigue, reduced quality of life and declines in physical function are common in patients undergoing chemotherapy for acute myeloid leukaemia (AML).
- Trial name
- NCT01170598
- Testing
- Exercise
- Where
- Canada
- Volunteers
- 35 people
- Sponsor
- Toronto Rehabilitation Institute
Spinal Cord Injury
Acute Effect of Ventilatory Support During Exercise in Spinal Cord Injury
The investigators have an existing exercise program (N>70) with a unique population of individuals with spinal cord injury (SCI) who have been enrolled in Functional Electrical Stimulation - Rowing Training (FES-RT) for at least…
- Trial name
- NIV-Ex-CS (NCT03267212)
- Testing
- Non-invasive ventilation(NIV), Functional Electrical Stimulation Row Training (FESRT)
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Spaulding Rehabilitation Hospital
Prostate Cancer
Acute Effects of Exercise on the Cortical Silent Period in Prostate Cancer Patients
In Canadian men, prostate cancer (PCa) is the most prevalent form of cancer and the third leading cause of cancer-related death.
- Trial name
- NCT01715064
- Testing
- Exercise
- Where
- Canada
- Volunteers
- 36 people
- Sponsor
- University of Guelph-Humber
Endothelial Dysfunction
The Effects of Resveratrol and Acute Exercise on Endothelial Function in Postmenopausal Women
This pilot study plans to learn more about the aging of blood vessels and arteries in women. As women age and go through menopause, their risk for cardiovascular disease increases.
- Trial name
- NCT02256540
- Testing
- Climara, Resveratrol
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Acute Myocardial Infarction
Effects of Cardiac Rehabilitation on High Mobility Group Box-1 Levels After Acute Myocardial Infarction
This purpose of this study is to examine the relationship between HMGB-1 and postinfarction predictors of outcome such as cardiopulmonary and echocardiographic parameters before and after a 6-month exercise-based cardiac…
- Trial name
- NCT00755131
- Testing
- Exercise-based Cardiac Rehabilitation program
- Where
- Italy
- Volunteers
- 75 people
- Sponsor
- Federico II University
Insulin, Exercise
Safety and Efficacy of Combining Intranasal Insulin & Acute Exercise
To determine if physical activity engagement alters the dose-response profile and safety of administration of insulin into the intranasal mucosa.
- Trial name
- NCT04292535
- Testing
- 20 IU NovoLog Insulin aspart into the intranasal mucosa, 40 IU NovoLog Insulin aspart into the intranasal mucosa, 60 IU NovoLog Insulin aspart into the intranasal mucosa
- Where
- United States
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Michigan State University
Breast Cancer
Acute Exercise Cardioprotection From Doxorubicin
In rodents, a single bout of exercise prior to injection of a chemotherapy agent used to treat breast cancer prevents or attenuates a number of markers of cardiac injury.
- Trial name
- NCT02006979
- Testing
- exercise
- Where
- Canada
- Volunteers
- 27 people
- Sponsor
- University of British Columbia
Congenital Heart Disease
Acute Effects of Inhaled Treprostinil in Fontan Patients
In this pilot study investigators propose to explore the effects of a locally delivered inhaled pulmonary vasodilator (inhaled treprostinil) on exercise performance, pulmonary blood flow, venous pressure response and vascular…
- Trial name
- NCT02769624
- Testing
- Treprostinil
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Heart Disease, Heart Failure With Preserved Ejection Fraction
Acute Effects of Inorganic Nitrite on Cardiovascular Hemodynamics in Heart Failure With Preserved Ejection Fraction
Heart failure with preserved ejection fraction (HFpEF) is a major public health problem that has no proven effective treatment. This study assessed the effects of acute nitrite administration on resting and exercise hemodynamics…
- Conditions
- Heart Disease, Heart Failure With Preserved Ejection Fraction, Exercise Intolerance, Pulmonary Hypertension
- Trial name
- NCT01932606
- Testing
- Nitrite
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Barry Borlaug
Osteoporosis, Aging
Exercise Mode and Acute Bone Resorption
Endurance exercise is often recommended to improve cardiometabolic health and maintain bone health throughout life and to prevent osteoporotic fracture.
- Trial name
- NCT04815824
- Testing
- Exercise Mode
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Stroke
A Study in Chinese Patients to Compare How Tenecteplase and Alteplase Given After a Stroke Improve Recovering of Physical Activity
This study is open to Chinese adults who had an ischaemic stroke, which means that blood vessels in the brain are blocked. To resolve blood clots, people in the study get either tenecteplase or alteplase within 4 hours and 30…
- Trial name
- ORIGINAL (NCT04915729)
- Testing
- tenecteplase, alteplase
- Where
- 55 sites in China
- Volunteers
- 1,489 people
- Sponsor
- Boehringer Ingelheim
Heart Failure
Acute Effects of Beet Juice Consumption on Exercise Capacity in Heart Failure
The purpose of this project will be to determine whether consumption of beet juice concentrate prior to exercise may acutely improve exercise tolerance in patients with heart failure.
- Trial name
- NCT01946542
- Testing
- beet juice concentrate
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Jason Allen, Ph.D.
Aging
Sex Differences in Vascular Responses to Exercise
A key early event in cardiovascular disease development is endothelial dysfunction, characterized by impaired flow-mediated dilation.
- Trial name
- NCT04128215
- Testing
- Control Period, Exercise Period
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Florida
Eating Disorders
Response to Acute Exercise in Eating Disorders
Individuals with eating disorders (ED) represent a high-priority clinical population, with among the highest mortality rates of any psychiatric disorder, and driven exercise (DEx) is a symptom evidenced in up to 80% of those with…
- Trial name
- NCT06213883
- Testing
- Biobehavioral Response to in-lab exposure to physical activity
- Where
- 2 sites in United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Acute Exercise, Heat Exposure
The Influence of Capsaicin Gel During Exercise Within the Heat
The purpose of this study is to examine the human thermoregulatory impact of applying a commercially available capsaicin gel to the skin prior to moderate intensity walking under heated conditions.
- Trial name
- NCT05298202
- Testing
- Capsaicin, Control Gel, Exercise
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Nebraska