Clinical trials: Acute Post-surgical Pain
Analgesia, Acute Pain
Comparison of the Effects of QLB 2 and QLB 3 on Post-operative Analgesia in Cesarean Section Surgery
This study evaluates the post-operative analgesic effects of quadratus lomborum block 2 and 3 (QLB 2, 3) in patients having cesarean section with spinal anesthesia.
- Conditions
- Analgesia, Acute Pain, Chronic Pain
- Trial name
- NCT04364906
- Testing
- Regional anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Ondokuz Mayıs University
Symptomatic Irreversible Pulpitis
Preoperative Acetaminophen- Caffeine- Codeine Combination and Anaesthetic Success in Patients With Acute Pulpitis
The aim of the study is to evaluate the effect of preoperative administration of acetaminophen- codeine -caffeine combination on the success of the inferior alveolar nerve block versus bacetaminophen alone or placebo in patients…
- Trial name
- NCT04202406
- Testing
- Acetaminophen and codeine and caffeine, Acetaminophen
- Where
- Egypt
- Volunteers
- 69 people
- Sponsor
- Cairo University
Unilateral Cataract Extraction, Congenital Cataract
A Randomized Study in Children Ages Birth Through Three Years Undergoing Unilateral Cataract Extraction With or Without Lens Replacement
The purpose of this study is to evaluate the effect of OMS302 compared to phenylephrine when administered in irrigation solution during cataract extraction on intraoperative pupil diameter, acute postoperative pain, and safety in…
- Trial name
- ILR7 (NCT02132312)
- Testing
- OMS302, Phenylephrine HCl
- Where
- 11 sites in United States
- Volunteers
- 78 people
- Sponsor
- Omeros Corporation
Post-surgical Pain, Pain, Acute
Online Psychology Program for Chronic Pain After Surgery
This project will evaluate the feasibility of a new fully self-guided online Acceptance and Commitment Therapy (ACT) program entitled Advancing Online Psychology Tools for the Transitional Pain Service (ADOPT-TPS), developed on…
- Conditions
- Post-surgical Pain, Pain, Acute, Pain, Chronic, Post-Surgical Pain, Chronic
- Trial name
- ADOPT-TPS (NCT06455345)
- Testing
- Self-Guided Online ACT Program, Treatment As Usual
- Where
- 2 sites in Canada
- Volunteers
- 68 people
- Sponsor
- University Health Network, Toronto
Juvenile; Scoliosis, Scoliosis Idiopathic
Digital Health Psychosocial Intervention for Adolescent Spine Surgery Preparation and Recovery
This is a randomized controlled trial to test effectiveness of the SurgeryPal intervention vs. education control to improve acute and chronic pain and health outcomes in youth undergoing major musculoskeletal surgery.
- Conditions
- Juvenile; Scoliosis, Scoliosis Idiopathic, Scoliosis; Adolescence, Scoliosis;Congenital
- Trial name
- SurgeryPal (NCT04637802)
- Testing
- CBT (SurgeryPal), Education
- Where
- United States
- Volunteers
- 433 people
- Sponsor
- Seattle Children's Hospital
Breast Cancer
Pecs II Block and PaB Could be an Alternative in Breast Surgery
The association between ultrasound-guided Pecs II block and parasternal block can represent a valid alternative in the management of acute and postoperative pain syndrome after quadrantectomy with or without axillary dissection.
- Trial name
- NCT02865265
- Testing
- Pecs II and parasternal blocks
- Volunteers
- 180 people
- Sponsor
- Emiliano Petrucci
Cardiac Disease, Analgesia
Parasternal Block for Cardiac Surgery
This study examine the effect of Parasternal Intercostal Nerve Blocks with local anesthetic on pain control in patients undergoing non-emergent cardiac surgery in a prospective controlled trial.
- Conditions
- Cardiac Disease, Analgesia, Acute Pain, Postoperative Pain
- Trial name
- Parasternal (NCT04319588)
- Testing
- Parasternal Block+ Infiltration with local anesthetic of access to thoracic drainage, Infiltration with local anesthetic of access to thoracic drainage
- Where
- Italy
- Volunteers
- 126 people
- Sponsor
- Campus Bio-Medico University
Pain, Postoperative, Pain, Chronic
Naldebain for Pain Control After Bariatric Surgery
Laparoscopic gastric sleeve and bypass surgeries the most common bariatric procedures for weight loss and improved management of metabolic syndromes.
- Conditions
- Pain, Postoperative, Pain, Chronic, Bariatric Surgery, Obesity
- Trial name
- NCT04651361
- Testing
- Dinalbuphine sebacate
- Where
- 2 sites in Taiwan
- Volunteers
- 60 people
- Sponsor
- E-DA Hospital
Perioperative Care, Chronic Post-operative Pain
Optimized Acute Pain Control With Parecoxib in Uniportal Video-assisted Thoracoscopic Surgery.
Chronic pain after thoracic surgery has been a bothering problem since the era of thoracotomy. The prevalence of chronic pain no matter in thoracotomy or video-assisted thoracoscopic surgery is about 30 to 47%.
- Trial name
- NCT05150431
- Testing
- Parecoxib
- Where
- Taiwan
- Volunteers
- 58 people
- Sponsor
- National Taiwan University Hospital
Other Acute Postoperative Pain, Systemic Inflammatory Response Syndrome
Systemic Inflammation Versus Acute Pain in Total Knee Arthroplasty (TKA)
In this study we evaluate if there is a correlation between acute pain and systemic inflammatory markers after total Knee Arthroplasty (TKA).
- Trial name
- NCT01322074
- Where
- Denmark
- Volunteers
- 120 people
- Sponsor
- Hvidovre University Hospital
Acute Pain, Post Operative Pain
Study of MR-107A-02 for the Treatment of Acute Postoperative Pain Following Bunionectomy
MR-107A-02 is being studied to investigate its efficacy and safety for treatment of acute pain after bunionectomy.
- Conditions
- Acute Pain, Post Operative Pain, Pain
- Trial name
- NCT06215820
- Testing
- MR-107A-02, Tramadol, Bunionectomy
- Where
- 15 sites in United States
- Volunteers
- 410 people
- Sponsor
- Viatris Specialty LLC
Esketamine, Pregabalin
Esketamine Combined With Pregabalin on Acute Postoperative Pain in Patients Undergoing Resection of Spinal Neoplasms.
Postsurgical pain is now known to be one of the most common and difficult-to-treat complications of surgery. severe postoperative pain can significantly impair patients' quality of life, social functioning and contribute to…
- Conditions
- Esketamine, Pregabalin, Acute Postoperative Pain, Neurosurgical Procedures
- Trial name
- NCT05096468
- Testing
- S-ketamine and pregabalin
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Beijing Tiantan Hospital
Preemptive Peripheral Nerve Block, Pain, Postoperative
Preemptive Analgesic Effects of Rectus Sheath Block in Laparoscopic Cholecystectomy Patients
The purpose of this study was to investigate the effectiveness of preemptive effect of rectus sheath block (RSB) and intercostal nerve block (ICNB) on postoperative visceral pain in laparoscopic cholecystectomy (LLC).
- Conditions
- Preemptive Peripheral Nerve Block, Pain, Postoperative, Acute Pain
- Trial name
- NCT03413280
- Testing
- Ultrasound guided Rectus sheath block, Intercostal nerve block
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Asan Medical Center
Pain, Acute Postoperative, Trauma Injury
Patient-Titrated Automated Intermittent Boluses of Local Anesthetic vs. a Continuous Infusion Via a Perineural Catheter for Postoperative Analgesia
This will be a randomized comparison of continuous local anesthetic infusion with patient controlled boluses (PCA) to patient-titratable automated boluses with patient controlled boluses (PCA) for both infraclavicular and…
- Trial name
- NCT05091905
- Testing
- Continuous Infusion of ropivacaine 0.2%, Titratable Automated Intermittent Boluses of ropivacaine 0.2%
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of California, San Diego
Postoperative Pain
Effects of Perioperative Intravenous Lidocaine and Ketamine on Acute and Chronic Pain After Open Nephrectomy
Open nephrectomy is one of the most common surgical procedures in urologic practice. Pain after surgery remains a significant clinical problem as it impairs recovery adversely and may lead to the transition to chronic pain.
- Trial name
- NCT02653651
- Testing
- Ketamine, Lidocaine
- Where
- Tunisia
- Volunteers
- 60 people
- Sponsor
- University Tunis El Manar
Acute Postoperative Pain, Chronic Postoperative Pain
Comparison of the Efficacy and Safety of Intravenous Buprenorphine Administered Via PCA System Versus Oxycodone in the Management of Postoperative Pain After Video-Assisted Thoracoscopic Surgery
The goal of this clinical trial is to learn whether intravenous buprenorphine administered via a patient-controlled analgesia (PCA) system provides effective and safer postoperative pain control than intravenous oxycodone PCA in…
- Conditions
- Acute Postoperative Pain, Chronic Postoperative Pain, Toracosurgery, Video-assisted Thoracis Surgery (VATS)
- Trial name
- NCT07434427
- Testing
- Group B (Buprenorphine), Group O (Oxycodone)
- Where
- Poland
- Volunteers
- 200 people
- Sponsor
- Medical University of Silesia
Acute Post Operative Pain, Chronic Post Operative Pain
Combined Use of Naldebain® ER Injection and Precedex® After VATS
The goal of this clinical trial is to investigate the effects of combined use of Naldebain® ER Injection and Precedex® in patients received video-assisted thoracoscopic surgery.
- Conditions
- Acute Post Operative Pain, Chronic Post Operative Pain, Postoperative Complications
- Trial name
- NCT06176222
- Testing
- PRECEDEX INJ★ 2ML, Normal saline
- Where
- Taiwan
- Volunteers
- 70 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Anesthesia, Local, Anesthesia
Regional Anesthesia in Pediatric Orthopaedic Patients
To identify the benefits from regional anesthesia use as pain management in the pediatric population by delineating the differences in efficacy of continuous nerve blockade versus single-shot techniques after pediatric…
- Conditions
- Anesthesia, Local, Anesthesia, Orthopedic Disorder
- Trial name
- NCT04669145
- Testing
- Ropivacaine
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Ochsner Health System
Lung Diseases
The Effectiveness of Acupressure for Managing Postoperative Pain and Anxiety in Patients With Thoracoscopic Surgery
The purpose of this study is to explore the effectiveness of acupressure for managing postoperative pain, anxiety, analgesia consumption, early ambulation, and comfort in patients with thoracoscopic surgery.
- Trial name
- NCT04595253
- Testing
- acupressure
- Where
- Taiwan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Wei-Fen Ma
Pain, Postoperative, Breast Cancer
Using Bupivacaine Locally in the Mastectomy Drains to Control Postoperative Pain
in this study we are investigating the role of instillation of Bupivacaine through surgical drains at the end of mastectomy surgeries in controlling post operative pain and decreasing their pain killers requirement in the early…
- Trial name
- NCT03799757
- Testing
- 40ml of 0.25% bupivacaine, 40ml of 0.9% normal saline
- Where
- Egypt
- Volunteers
- 168 people
- Sponsor
- Alexandria University