Clinical trials: Acute Post-surgical Pain
Nephrectomy
Comparing 3 Different Types of Pain Blocks After Laparoscopic Nephrectomy
All three methods of postoperative analgesia have been shown to decrease postoperative pain control in nephrectomy patients, the three methods have never been compared to each other.
- Trial name
- NCT03581539
- Testing
- Transverses Abdominis Plane (TAP) block, Quadratus Lumborum (QL) block, Surgeon Infiltration using Exparel
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Indiana University
Appendicitis
A Comparison of UGBRS Block and Local Infiltration
In this research study, the investigators are trying to find out which of the two methods of injecting local anesthetics (at the site of the belly button cut or by ultrasound guided rectus sheath block) will provide better pain…
- Trial name
- NCT02352519
- Testing
- UGBRSB, Local Infiltration
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Acute Pain, Pain, Postoperative
Ketamine in Colorectal Surgery
This study will evaluate the effectiveness of ketamine infusions in the management of acute pain following open or laparoscopic colorectal surgery cases.
- Conditions
- Acute Pain, Pain, Postoperative, Colorectal Surgery
- Trial name
- KCRS (NCT02785003)
- Testing
- Ketamine, Acetaminophen, Opioid
- Where
- United States
- Sponsor
- Medical College of Wisconsin
Pain, Acute, Pain, Postoperative
The Impact of Esmolol Administration on Postoperative Recovery
The aim of this study will be to investigate the effect of a continuous infusion of low dose esmolol on intraoperative and postoperative opioid consumption, as well as on postoperative recovery and chronic pain
- Conditions
- Pain, Acute, Pain, Postoperative, Pain, Chronic Post-Surgical, Esmolol
- Trial name
- esmolol (NCT05567822)
- Testing
- Esmolol Hydrochloride, normal saline
- Where
- Greece
- Volunteers
- 70 people
- Sponsor
- Aretaieion University Hospital
Chronic Pain, Anaesthesia
Comprehensive Pain Programme to Determine Mechanism of Transition of Acute to Chronic Postsurgical Pain
To determine whether central sensitization is a mechanism of CPSP (chronic postsurgical pain) in women who will develop CPSP compared to women with no CPSP after hysterectomy.
- Conditions
- Chronic Pain, Anaesthesia, Genetics Predisposition
- Trial name
- TAHP (NCT02025153)
- Testing
- pain testing
- Where
- Singapore
- Volunteers
- 216 people
- Sponsor
- KK Women's and Children's Hospital
Hypertensive Disease, Pain, Postoperative
Effect of Acute Arterial Hypertension on Morphine's Requirements and Postsurgical Pain.
The purpose of this randomized clinical trial is to evaluate the effect of acute arterial hypertension maintained during surgery on morphine's requirements in patients undergoing laparoscopic cholecystectomy
- Trial name
- NCT01897155
- Testing
- SBP 20-30% over baseline, SBP 20-30% under baseline
- Where
- Chile
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidad Catolica de Chile
Pain, Acute, Postoperative Pain
PENG Block With Two Diffirent Volume
Hip fractures are morbid conditions, especially in elderly patients, and their treatment is usually surgical. Pericapsular nerve group block is a newly defined block and targets the hip capsule.
- Conditions
- Pain, Acute, Postoperative Pain, Hip Fractures
- Trial name
- NCT05358587
- Testing
- Ultrasound guided PENG block with 20 mL Local Anesthetic solution, Ultrasound guided PENG block with 30 mL Local Anesthetic solution
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Samsun University
Infrainguinal Peripheral Artery Disease, Peripheral Arterial Disease
Post-Market Registry of AURYON Atherectomy Device in Subjects Affected With Infrainguinal Peripheral Artery Disease
The PATHFINDER Registry is a prospective, non-randomized, single arm, multicenter observational study. This pilot registry is aimed to evaluate the performance (peri-procedural) and clinical outcomes (intermediate and long-term)…
- Conditions
- Infrainguinal Peripheral Artery Disease, Peripheral Arterial Disease, PAD
- Trial name
- PATHFINDER (NCT04229563)
- Testing
- AURYON Atherectomy System
- Where
- 10 sites in United States
- Volunteers
- 102 people
- Sponsor
- Angiodynamics, Inc.
Analgesia, Pain, Postoperative
Comparison Between the Caudal Block and Other Methods of Postoperative Pain Relief in Children Undergoing Circumcision
Prospective, randomized, case-controlled trial study. Observation post-operatively: Aims: This study aimed to compare the effectiveness of the caudal block CB with other methods of postoperative pain release.
- Conditions
- Analgesia, Pain, Postoperative, Pain, Acute
- Trial name
- paincontrol (NCT06086106)
- Testing
- caudal block, Dorsal Penile Nerve Block DPNB, Systemic opioids
- Where
- Bahrain
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Salmaniya Medical Complex
Post Operative Pain, Anesthesia
Dexmedetomidine and Dexamethasone Added as Adjuvant Infraclavicular Brachial Plexus Block in Upper Limb Surgery
The aim of this study was to investigate the effect of dexmedetomidine and dexamethasone added during USG-guided infraclavicular block on block onset time, total block time and time to first analgesic need in patients undergoing…
- Conditions
- Post Operative Pain, Anesthesia, Acute Pain
- Trial name
- NCT06779604
- Testing
- Infraclavicular Block with Dexmedetomidine and Dexamethasone
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Umraniye Education and Research Hospital
Appendicitis Acute
Low vs Medium Pressure Pneumoperitoneum
The purpose of this study is to asses whether the pressure used for the pneumoperitoneum during laparoscopic surgery in children affects their postoperative pain levels.
- Trial name
- LoMePneu (NCT04949659)
- Testing
- Laparoscopic appendectomy
- Where
- Switzerland
- Volunteers
- 250 people
- Sponsor
- University Children's Hospital, Zurich
Pain, Postoperative, Complication, Postoperative
Optimizing Acute Post-Operative Dental Pain Management Using New Health Information Technology
The investigators seek to implement a dental patient reported outcomes system using mobile phone and text messaging to target the over-reliance on pre-emptively prescribed opioids by dental providers.
- Trial name
- AHRQPRO (NCT03881891)
- Testing
- Follow-app intervention arm
- Where
- 2 sites in United States
- Volunteers
- 1,525 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Pain, Postoperative, Ketamine Adverse Reaction
Efficacy of Ketamine in Post Anesthesia Recovery Room
Observational study to assess efficacy of IV ketamine bolus when used in the post anesthesia recovery unit for uncontrolled pain despite use of opioids.
- Conditions
- Pain, Postoperative, Ketamine Adverse Reaction, Pain, Refractory, Pain, Intractable
- Trial name
- NCT04701008
- Testing
- Ketamine
- Where
- Canada
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Lung Cancer
Acute and Chronic Pain After Video-assisted Thoracoscopic Surgery for Lung Cancer
The aim of this study is to evaluate whether preoperative CT- guided hookwire localization would influence the incidence and intensity of acute and chronic pain after VATS.
- Trial name
- NCT05478460
- Testing
- Hookwire localization
- Where
- China
- Volunteers
- 161 people
- Sponsor
- Fudan University
Pain
Pregabalin on Interleukin-6 Levels in Living Donor Kidney
Pregabalin, a ligand for alfa2delta subunits of voltage-gated calcium channels, has been shown to be an effective adjuvant therapy for acute postoperative pain, by inhibiting central sensitization.
- Trial name
- NCT01529190
- Testing
- Pregabalin
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Federal University of São Paulo
Post Operative Pain, Acute
Comparing Efficacy of Different Drugs Combinations for Serratus Anterior Block for Thoracotomy
We aim to compare efficacy and efficiency of serratus anterior block with bupivacaine alone to bupivacaine/magnesium and bupivacaine /nalbuphine in postoperative analgesia for thoracotomy surgery.
- Trial name
- NCT05565235
- Testing
- patients will receive intraoperative serratus block with bupivacaine, serratus block with bupivacaine /magnesium, serratus block with bupivacaine with nalbuphine
- Where
- Egypt
- Volunteers
- 78 people
- Sponsor
- Cairo University
Pain, Postoperative
Efficacy and Safety of Intranasal Morphine for Pain After Elective Orthopedic Surgery
Multiple-center, multiple-dose, randomized, double-blind, six-arm, active- and placebo-controlled study in patients with moderate to severe post-surgical pain from elective orthopedic surgery with safety observed for a total of…
- Trial name
- NCT00390039
- Testing
- Intranasal Morphine, IV morphine
- Where
- 7 sites in United States
- Volunteers
- 256 people
- Sponsor
- Javelin Pharmaceuticals
Fascial Plane Block, Pain, Postoperative
Transverse vs. Longitudinal Serratus Anterior Plane Block in Breast Surgery
The aim of this prospective, randomized controlled trial is to compare the analgesic efficacy of transverse versus longitudinal ultrasound probe orientations during Serratus Anterior Plane (SAP) block in patients undergoing…
- Conditions
- Fascial Plane Block, Pain, Postoperative, Breast Surgery, Acute Pain
- Trial name
- NCT07739277
- Testing
- Transverse SAP Block, Longitudinal SAP Block
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Ankara Etlik City Hospital
Postoperative Pain
Auricular Acupuncture for Pain Relief After Ambulatory Knee Arthroscopy
The aim was to investigate whether auricular acupuncture is superior to sham acupuncture in relief of acute postoperative pain and in reduction of analgesics consumption on demand and their side effects in patients after…
- Trial name
- NCT00233857
- Testing
- Auricular acupuncture
- Where
- Germany
- Volunteers
- 120 people
- Sponsor
- University Medicine Greifswald
Postoperative Acute Pain, Opioid Consumption
Erector Spinae Block -Dexmedetomidine
Postoperative pain is common after spinal surgeries, including lumbar disc surgery. Surgical anesthesia and perioperative analgesic regimen are aimed at complete intraoperative amnesia, deep analgesia, effective control of…
- Trial name
- esp -dex (NCT06264739)
- Testing
- esp Dexmedetomidine (dekstomid), esp remifentanyl (ultiva)
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people
- Sponsor
- Aydin Adnan Menderes University