Clinical trials: Acute Post-surgical Pain
Postoperative Pain, Acute
Erector Spinae Plane Block Versus Quadratus Lumborum Block for Open Renal Surgeries in Children
Open renal surgeries are associated with significant postoperative pain; early control of the perioperative pain is associated with decrease of hemodynamic variations during the surgery, early mobilization, better quality of…
- Trial name
- NCT05386121
- Testing
- Ultrasound-guided Erector Spinae Plane Block, Ultrasound-guided Quadratus Lumborum Block, Ultrasound Machine
- Volunteers
- 60 people
- Sponsor
- Cairo University
Laparoscopic Surgery, Post Operative Pain, Acute
Maneuvers to Reduce Laparoscopic Pain
Laparoscopic surgery has revolutionized surgical care by reducing morbidity and improving post operative recovery. Laparoscopic surgery involves the use of carbon dioxide for insufflation to achieve optimal visualization.
- Conditions
- Laparoscopic Surgery, Post Operative Pain, Acute, Pneumoperitoneum
- Trial name
- NCT07583433
- Testing
- Smoke Evacuation Group, Recruitment Breath Group, Control Group
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Acute Post-operative Pain, Nerve Block
Comparison of Analgesia Efficacy of Transversus Abdominis Plane Block and Posterior Approach Quadratus Lumborum Block
Prostate cancer is the second most common cancer and the fifth in cancer-related deaths. Open radical retropubic prostatectomy is the most common surgical treatment for localized prostate cancer.
- Conditions
- Acute Post-operative Pain, Nerve Block, Prostate Cancer
- Trial name
- NCT06075498
- Testing
- transversus abdominis plane block,
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Muğla Sıtkı Koçman University
Postoperative Depression
The Impact of Preoperative Chronic Pain on Postoperative Depressive States in Elderly Patients Undergoing Joint Replacement Surgery: A Secondary Analysis Based on Prospective Data
Background: Postoperative depression is a significant complication that hinders recovery in elderly patients undergoing joint replacement surgery.
- Trial name
- NCT07403838
- Where
- China
- Volunteers
- 575 people, healthy volunteers welcome
- Sponsor
- Chinese PLA General Hospital
Pain, Postoperative, Preemptive Peripheral Nerve Block
Preemptive Analgesic Effects of Popliteal Sciatic Nerve Block in Patients With Bilateral Hallux Valgus Surgery
The purpose of this study was to investigate the preemptive effect of ultrasound guided popliteal scistic nerve block on postoperative acute pain in patients with bilateral hallux valgus.
- Conditions
- Pain, Postoperative, Preemptive Peripheral Nerve Block, Acute Pain
- Trial name
- NCT03414593
- Testing
- Ultrasound guided popliteal sciatic nerve block with 0.2% ropivcaine
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Asan Medical Center
Appendicitis Acute, Pediatrics
TAP Block Versus Local Anesthesia Wound Infiltration for Postoperative Pain Relief After Appendicectomy in Children
When performing laparoscopic appendectomy in children, regional anesthetic techniques are rou-tinely used concomitantly with general anesthesia.
- Conditions
- Appendicitis Acute, Pediatrics, Analgesia
- Trial name
- PABLO (NCT04969133)
- Testing
- Levobupivacaine Hydrochloride 2.5 MG/ML
- Where
- France
- Volunteers
- 110 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Acute Pain, Opioid Analgesic Adverse Reaction
the Efficacy and Safety of Oliceridine Fumarate Injection for Acute Pain After Abdominal Surgery
The goal of this clinical trial is to learn if Oliceridine fumarate injection works to treat acute pain after abdominal surgery. It will also learn about the safety of Oliceridine fumarate injection.
- Trial name
- NCT06530563
- Testing
- Oliceridine Injection [Olinvyk], Sufentanil Citrate
- Where
- China
- Volunteers
- 606 people
- Sponsor
- Xiangya Hospital of Central South University
Breast Cancer, Post Operative Pain
Perioperative Mirogabalin for Pain Relief After Modified Radical Mastectomy
This study aims to evaluate whether perioperative mirogabalin can reduce postoperative pain and morphine consumption in female patients undergoing modified radical mastectomy for breast cancer.
- Trial name
- NCT07880821
- Testing
- Mirogabalin
- Volunteers
- 50 people
- Sponsor
- Cairo University
Acute Pulpitis
Postoperative Pain Associated With Three Endodontic Rotary Systems
Assessment of postoperative pain after root canal treatment using different rotary systems.
- Trial name
- NCT03065777
- Testing
- ONE ENDO, F6 SKYTaper, ProTaper Universal
- Where
- Egypt
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pain, Postoperative, Breast Cancer
Using Bupivacaine Locally in the Mastectomy Drains to Control Postoperative Pain
in this study we are investigating the role of instillation of Bupivacaine through surgical drains at the end of mastectomy surgeries in controlling post operative pain and decreasing their pain killers requirement in the early…
- Trial name
- NCT03799757
- Testing
- 40ml of 0.25% bupivacaine, 40ml of 0.9% normal saline
- Where
- Egypt
- Volunteers
- 168 people
- Sponsor
- Alexandria University
Acute Pain
The Effect of Erector Spinae Plane Block Performed Under Direct Vision on Postoperative Pain in Spine Surgery
Spine surgery is typically associated with severe postoperative pain. Although the number of spine surgeries has increased day by day, postoperative pain management have been limited.
- Trial name
- ESPOUSES (NCT03960528)
- Testing
- Erector spinae plane block, Control group
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Bezmialem Vakif University
Postoperative Pain After Cesarean Section
Interferential Current and Transcutaneous Electrical Nerve Stimulation for Pain After Cesarean Section
This study aims to compare the immediate and short-term effects of interferential current therapy and conventional transcutaneous electrical nerve stimulation (TENS) with placebo stimulation on pain and postpartum comfort…
- Trial name
- IC-TENS-CS (NCT07847502)
- Testing
- Conventional TENS, Interferential Current Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Dilara Özen Oruk
Acute Postoperative Pain, Motor Activity
Axillary Brachial Plexus Block Using 0.25% Bupivacaine Versus Using 0.19%Bupivacaine in Pediatrics
Postoperative pain is a common manifestation in orthopedic patients, mainly due to intraoperative tissue damage and inadequate intraoperative pain assessment and management .Axillary brachial plexus block provides motor and…
- Trial name
- NCT05386095
- Testing
- 0.25%Bupivacaine Axillary brachial plexus block, 0.19% Bupivacaine Axillary brachial plexus block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Acute Pain, Postoperative
Multicenter Study to Compare Intravenous and Oral Acetaminophen for the Treatment of Acute Moderate to Severe Pain
The purpose of this study is to compare intravenous (IV) and oral acetaminophen for the treatment of acute moderate to severe pain in combination with standard patient-controlled analgesia (PCA) in adult subjects following total…
- Trial name
- NCT02746263
- Testing
- IV acetaminophen, Oral acetaminophen, Morphine
- Where
- 2 sites in United States
- Volunteers
- 1 people
- Sponsor
- Mallinckrodt
Acute Pain, Postoperative, Postoperative Pain
Characterization of Acute Pain
This study aims to better understand how acute pain and responses to pain treatment can be measured in children and adolescents using a non-invasive device.
- Conditions
- Acute Pain, Postoperative, Postoperative Pain, Acute Pain
- Trial name
- NCT07336264
- Testing
- AlgometRx Nociometer
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Children's National Research Institute
Postoperative Pain, Postoperative Pain, Acute
Incidence of Chronic Pain After Sternotomy
Chronic postoperative pain is a well-known problem. Chronic postoperative pain is defined as pain that begins following a surgical procedure and persists for more than 2 months without other obvious causes such as infection or…
- Conditions
- Postoperative Pain, Postoperative Pain, Acute, Postoperative Pain, Chronic, Sternotomy
- Trial name
- NCT05357963
- Testing
- Sternotomy application
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Ankara City Hospital Bilkent
Acute Pain
Analgesic Efficacy of Paravertebral Morphine
The investigator will test the analgesic efficacy of paravertebral morphine as an adjuvant to local anesthetics for acute postoperative pain following breast surgery and renal surgery
- Trial name
- NCT03379987
- Testing
- PVB morphine, PVB bupivacaine
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Assiut University
Pain, Postoperative, Multimodal Analgesia
Comparison of the Rhomboid Intercostal Block and Serratus Posterior Superior Intercostal Plane Block
Video-assisted thoracic surgery (VATS) is widely performed for the management of various thoracic pathologies and is generally associated with reduced surgical trauma compared with open thoracotomy.
- Conditions
- Pain, Postoperative, Multimodal Analgesia, Rhomboid Intercostal Block, Serratus Posterior Superior Intercostal Plane Block
- Trial name
- NCT07650877
- Testing
- Rhomboid Intercostal Block, Serratus Posterior Superior Intercostal Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Ankara City Hospital Bilkent
Postoperative;Pain Management
Effects of Serratus Posterior Superior Intercostal Plane Block and Pectoralis Nerve Block in Coronary Artery Surgery
Postoperative analgesia is a critical risk factor for the development of pulmonary and cardiovascular complications in all types of chest surgery, particularly coronary artery bypass graft (CABG) surgery.
- Trial name
- NCT06242431
- Testing
- Group serratus posterior superior intercostal plane block (SPSIPB), Group pectoralis nerve block (PECS-II)
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Hitit University
Pain, Postoperative, Pain, Acute
'The Effect of Adding LFCN Block to PENG
The incidence of femoral neck fracture in Europe is 330/10000 per year. It is increasing every year due to the aging of the population.
- Conditions
- Pain, Postoperative, Pain, Acute, Nerve Block, Opioid Consumption
- Trial name
- NCT06226675
- Testing
- PENG Block, LFCN block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University