Clinical trials: Acute Post-surgical Pain
Postoperative Pain, Adults
Safety and Efficacy Evaluation of S (+) - Ketamine in Adults
A multicenter, randomized, open-label, active controlled pragmatic clinical trial that evaluates the safety and efficacy of S (+) -ketamine for postoperative acute pain in adults in perioperative settings.
- Conditions
- Postoperative Pain, Adults, Anesthesia
- Trial name
- NCT04837170
- Testing
- Conventional therapy + S (+)-Ketamine, Conventional therapy
- Volunteers
- 12,000 people
- Sponsor
- Chinese PLA General Hospital
Coxarthrosis, Pain, Postoperative
Lumbar ESPB in Hip Replacement Surgery
In this study, continuous erector spinae plane block (ESPB) will be compared to continuous epidural analgesia in patients undergoing elective hip replacement surgery.
- Conditions
- Coxarthrosis, Pain, Postoperative, Pain, Acute, Pain, Chronic
- Trial name
- ESPB_HIP (NCT06282666)
- Testing
- Spinal anesthesia, lumbar erector spinae plane block, Epidural analgesia
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Medical University of Lublin
Chronic Post Operative Pain
Longitudinal Study of Chronic Postsurgical Pain in Children and Adolescents
Chronic postsurgical pain is defined as pain that develops or intensifies following a surgical procedure. After major surgery, around 20% of children and adolescents develop chronic postsurgical pain, and, as part of it, negative…
- Trial name
- NCT05816174
- Where
- 3 sites in Switzerland
- Volunteers
- 281 people
- Sponsor
- Helen Koechlin
Postoperative Pain
Virtual Reality in Postoperative Acute Pain Management in Thoracic Surgery
This randomized controlled study is to investigate the effectiveness of VR headsets in reducing postoperative pain intensity among patients after having undergone thoracic surgical procedures.
- Trial name
- VRThx (NCT06097520)
- Testing
- VR Intervention
- Where
- Switzerland
- Volunteers
- 39 people
- Sponsor
- University Hospital, Basel, Switzerland
Breast Cancer Female
Efficacy of Transdermal Fentanyl Patches in Relief of Acute Postoperative Pain After Mastectomy
to determine the safety, efficacy and tolerability of transdermal fentanyl in patients undergoing mastectomy, as well as the postoperative consumption of analgesic.
- Trial name
- NCT03051503
- Testing
- The Transdermal Therapeutic System-Fentanyl (TTS-F), Intravenous patient-controlled analgesia (PCA) morphine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- South Egypt Cancer Institute
Postoperative Pain, Hip Fracture
Transcutaneous Nerve Stimulation for Post-operative Acute and Chronic Pain
Aim of the study to assess the efficacy of two modes of transcutaneous electrical nerve stimulation (TENS) on relief of postoperative acute pain after hip fracture surgery.
- Trial name
- NCT02642796
- Testing
- transcutaneous electric nerve stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Mustafa Kemal University
Analgesia
Acute Post-operative Pain in Colon Resections
Objective of the study is to compare three different analgesic techniques in patients undergoing laparoscopic colon resections: peridural catheter, patient controlled analgesia of endovenous morphine and patient controlled…
- Trial name
- ERAS-PO (NCT03403842)
- Testing
- Sublingual sufentanil tablet system, Peridural catheter, PCA Morphine
- Where
- Italy
- Volunteers
- 159 people
- Sponsor
- IRCCS San Raffaele
Postoperative Pain
Massage After Surgery To Help Treat Post-Operative Pain
Postoperative pain is often undertreated. Although studies have demonstrated that many patients experience a substantial degree of unrelieved pain following operative procedures and that this pain can increase the incidence of…
- Trial name
- NCT00057148
- Testing
- massage treatment
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- US Department of Veterans Affairs
Mastectomy, Rhomboid Intercostal Block
Effects of Rhomboid Intercostal Block on Postoperative Pain Management and Chronic Pain Incidence in Mastectomies
The goal of this clinical trial is to evaluate the effects of the Rhomboid Intercostal Block (RIB) on postoperative chronic pain prevalence at 3 months (primary outcome) and on acute pain control, total opioid consumption, and…
- Conditions
- Mastectomy, Rhomboid Intercostal Block, Chronic Pain Following Surgical Procedure for Cancer
- Trial name
- NCT06756048
- Testing
- Rhomboid Intercostal Nerve Block
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Koç University
Postoperative Pain, Acute
Comparative Study Between Caudal Epidural Block and Bilateral Erector Spinae Plane Block in Lumbosacral Spine Surgeries.
It is widely believed that major lumbosacral spine surgeries are associated with severe postoperative pain that may delay the functional recovery of the patient.
- Trial name
- NCT05729308
- Testing
- caudal epidural block, bilateral erector spinae plane block, general anesthesia with intravenous analgesia.
- Where
- Egypt
- Volunteers
- 78 people
- Sponsor
- Ain Shams University
Thoracotomy, Pain, Postoperative
Gabapentin Dosages for Postoperative Analgesia Following Open Thoracotomy
Gabapentin is a nerve medication that treats pain. The specific aim of the study is to compare the difference in the postoperative use of no gabapentin, 300 mg gabapentin 3x daily, or 300 mg gabapentin once at night.
- Trial name
- NCT05172570
- Testing
- Gabapentin
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Indiana University
Post-operation Pain
A Feasibility Dose-escalating Study of MDT-10013 for Acute Postoperative Pain Following Total Knee Arthroplasty
This is an open-label dose-escalating study to evaluate the tolerability and systemic exposure of MDT-10013 in men and women at least 18 years of age who are undergoing primary unilateral TKA.
- Trial name
- NCT02263222
- Testing
- MDT-10013
- Where
- 3 sites in United States
- Sponsor
- Medtronic Spinal and Biologics
Irreversible Acute Pulpitis, Root Canal Treatment
Evaluation of the Effects of Different Irrigation Solutions and Activation Methods on Postoperative Pain and Quality of Life in Root Canal Treatment
Brief Summary: This prospective randomized controlled clinical trial aims to evaluate the effects of different irrigation solutions (NaOCl, HEDP) and activation methods (conventional syringe irrigation, EDDY, diode laser) on…
- Trial name
- NCT07241650
- Testing
- Irrigation with Sodium Hypochlorite and Conventional Syringe, Irrigation with Sodium Hypochlorite and EDDY, Procedure: Irrigation with Sodium Hypochlorite and Diode Laser
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Ankara Yildirim Beyazıt University
Acut Postoperative Pain, Erector Spinae Plane Block
Comparison of Intertransverse Process and Erector Spinae Plane Blocks in Acute Postoperative Analgesia Management for Laparoscopic Cholecystectomy Patients
Laparoscopic cholecystectomy is considered the gold standard for the surgical treatment of benign gallbladder diseases; however, despite its minimally invasive nature, a significant proportion of patients experience substantial…
- Conditions
- Acut Postoperative Pain, Erector Spinae Plane Block, Intertransverse Process Block
- Trial name
- NCT07504705
- Testing
- Intertransverse Process Block, Erector Spinae Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Konya City Hospital
Postoperative Pain, Acute, Regional Anesthesia
Comparation of Bilateral and Unilateral Erector Spinae Plane Block
Although laparoscopic cholecystectomy is a minimally invasive surgery with many advantages, it is one of the operations with high postoperative pain scores. Opioids are frequently used to prevent postoperative pain.
- Conditions
- Postoperative Pain, Acute, Regional Anesthesia, Multimodal Analgesia
- Trial name
- NCT05152602
- Testing
- Bilateral Erector spinae plane block, Unilateral Erector spinae plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Ankara City Hospital Bilkent
Acute Postoperative Pain, Trajectory
Pain Trajectories and Predictors After Noncardiac Surgery in Elderly Patients
This study will use group-based trajectory modeling to identify the different postoperative pain trajectory groups that exist in a mixed surgical population (non-cardiac surgery) of elderly patients during the first seven days…
- Trial name
- NCT05865366
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Feng Gao
Acute Pain
Preventive Treatment of Pain After Dental Implant Surgery
The objective of this prospective randomized double-blind study was to evaluate the effects of the preoperative administration of dexketoprofen trometamol (DKT) on the pain perceived by patients after oral surgery for implant…
- Trial name
- UMU (NCT03107338)
- Testing
- DEXKETOPROFEN TROMETAMOL
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Universidad de Murcia
Acute Postoperative Pain After Cesarean Delivery
LI4 and SP6 Acupuncture for Pain After Cesarean Delivery
This randomized, sham-controlled clinical trial will evaluate the effectiveness of acupuncture at bilateral LI4 and SP6 as an adjunct to standard postoperative analgesia for acute pain after cesarean delivery.
- Trial name
- NCT07869589
- Testing
- Bilateral Acupuncture Protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Nigde Omer Halisdemir University
Cesarean Delivery, Postoperative Pain
The Effect of Intrathecal Morphine and Erector Spina Plan Block on Serum Cytokine Levels and Chronic Pain in Caesarean Section Surgery
Working Title The Effect of Intrathecal Morphine and Erector Spina Plan Block on Serum Cytokine Levels and Chronic Pain in Caesarean Section Surgery Study Description This study aims to evaluate the effects of intrathecal…
- Conditions
- Cesarean Delivery, Postoperative Pain, Cytokine Levels, Chronic Pain, Postoperative
- Trial name
- NCT06684015
- Testing
- İNTRATECHAL MORPHİNE GROUP, Erector Spinae Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Ankara University
Post Operative Pain, Acute, Arthroscopic Shoulder Surgery
Comparison Between Dexametidomedine\Bupivacaine and Plain Bupivacaine in Superior Trunk Block for Arthroscopic Shoulder Surgeries
Comparison between dexametidomedine\bupivacaine and plain bupivacaine in superior trunk block for arthroscopic shoulder surgeries
- Trial name
- NCT07046325
- Testing
- dexametedomidine, Bupivacain
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Ain Shams University