Clinical trials: Acute Post-surgical Pain
Postoperative Pain, Acute
Comparision of M-TAPA Versus TAPB After Laparoscopic Cholecystectomy
This randomized controlled study is designed to evaluate the postoperative analgesic effect of the ultrasound-guided modified thoracoabdominal nerves block through perichondrial approach (M-TAPA) in patients undergoing…
- Trial name
- NCT05207306
- Testing
- Type of interfascial plane block
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Seoul National University Hospital
Cardiac Surgery
Efficacy of Ultrasound Guided PIFB Versus Lidocaine Infusion on Postoperative Pain After Sternotomy
Chronic pain is a common complication after cardiothoracic surgery. The prevalence of post-sternoyomy pain syndrome (PSPS) ranges from 33% to 91%.
- Trial name
- NCT05885230
- Testing
- pecto intercostal fascial block using bupivacaine 0.25%, lidocaine infusion
- Where
- Egypt
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University
Pain, Postoperative, Acute Pain
EFFECT - EFFectiveness of ESPB (Erector Spinae Plane Block) in Laparoscopic Cοlectomies Trial
The aim of the trial is to study the efficacy of continuous bilateral Erector Spinae Plane Block (ESPB) in managing perioperative pain in patients who undergo elective laparoscopic colectomy.
- Conditions
- Pain, Postoperative, Acute Pain, Postoperative Complications, Pain
- Trial name
- EFFECT (NCT04879004)
- Testing
- Ropivacaine injection
- Where
- Greece
- Volunteers
- 40 people
- Sponsor
- Democritus University of Thrace
Pain
Remote Ischemic PreConditioning Effect on Postsurgical Pain
Remote Ischemic PreConditioning (RIPC) will improve the postoperative pain experience in patients undergoing abdominal surgery. Although abdominal surgery can be a lifesaving procedure many people have a significant amount of…
- Trial name
- RIPCEPP (NCT01383317)
- Testing
- Thigh Tourniquet (VBM Single Use Tourniquet Cuff Items 20-34-722SLZ-1)
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Wake Forest University Health Sciences
Acute Post-operative Pain
Panda: Evaluation of a Smartphone-based Perioperative Pain Assessment Tool
This study will evaluate Panda, a smartphone-based pain assessment tool. During a child's recovery from surgery, a Post-Anesthetic Care Unit nurse will assess their pain, which helps determine what medication they need.
- Trial name
- Panda (NCT01610882)
- Testing
- Panda first followed by manual pain assessment, Manual first followed by Panda pain assessment
- Where
- Canada
- Volunteers
- 144 people
- Sponsor
- University of British Columbia
Postoperative Pain, Cholelithiasis
Comparative Efficacy of ESPB and EOPB for Postoperative Analgesia in Laparoscopic Cholecystectomy: A Randomized Controlled Trial (External Oblique Intercostal Plan Block (EOPB) and Erector Spina Plan Block (ESPB) )
This randomized controlled clinical trial investigates the comparative efficacy of two novel regional anesthesia techniques - the Erector Spinae Plane Block (ESPB) and the External Oblique Intercostal Plane Block (EOPB) - for…
- Conditions
- Postoperative Pain, Cholelithiasis, Acute Pain
- Trial name
- NCT07057934
- Testing
- ESPB Block, EOPB Block, Standard Systemic Analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Pain, Postoperative, Intrathoracic Procedure
Cryoablation Effects on Acute and Chronic Pain After Thoracotomy and Thoracoscopy
The researchers will compare the common methods of post-surgical pain control, such as epidural or intercostal nerve block with a newer method called cryoablation.
- Trial name
- NCT06384664
- Testing
- Atricure's crysoSPHERE probe, Standard of Care
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Post Operative Pain, Acute
Subcostal Transversus Abdominis Block Versus Erector Spinae Block in Open Cholecystectomy
Open cholecystectomy is a surgical procedure involving the removal of the gallbladder through a traditional, open abdominal incision the surgeon makes an incision in the upper abdomen, exposes the gallbladder, and carefully…
- Trial name
- NCT06410911
- Testing
- Subcostal Transversus Abdominis Plane block in patients undergoing open cholecystectomy surgery., Erector Spinae Block in patients undergoing open cholecystectomy, Sbcostal transversus Abdominis block and erector spinae block for both groups
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sohag University
Postoperative Pain, Pain, Acute
Oral Use of Dexketoprofen/Tramadol for Acute Postoperative Pain in Total Hip Replacement With a Direct Anterior Approach.
Pain is a global public health issue and represents the most common reason for both physician consultation and hospital admissions .
- Trial name
- NCT04178109
- Testing
- Dexketoprofen/tramadol (27mg/75mg), Tramadol hydrochloride, Paracetamol
- Where
- Greece
- Volunteers
- 226 people, healthy volunteers welcome
- Sponsor
- KAT General Hospital
Acute Pre and Post Operative Pain
Acute Pain Assessment Using Facial Expression Analysis
Managing pain, which affects 20-50% of the population, is a major issue in daily clinical practice. Evaluation of pain intensity is essential to adapt treatment but as it mainly relies on self-report, this assessment is difficult…
- Trial name
- DEF-I (NCT03957967)
- Testing
- video taken
- Where
- France
- Volunteers
- 1,000 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Cardiac Surgery, Sternotomy
Pecto-Intercostal Fascial Plane Block Catheter Trial for Reduction of Sternal Pain
One of the most painful aspects of open heart surgery is the incision made through the skin and the sternum to access the heart (a "sternotomy").
- Conditions
- Cardiac Surgery, Sternotomy, Acute Pain
- Trial name
- NCT05054179
- Testing
- Ropivacaine 0.2% Injectable Solution Bolus, Normal Saline Infusion, Ropivacaine 0.2% Injectable Solution Infusion
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- University of British Columbia
Postoperative Pain, Acute
Modified Versus Conventional Serratus Anterior Plane Block
comparing preemptive analgesia with ultrasound guided modified serratus anterior plane block versus ultrasound guided serratus anterior plane block
- Trial name
- NCT05661253
- Testing
- 25 ml of bupivacaine 0.25% via serratus anterior block, 25 ml of bupivacaine 0.25% via modified serratus anterior palne block
- Where
- Egypt
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Acute Appendicitis, Acute Abdomen
Transversus Abdominis Plane Block in Acute Appendicitis Pain Managment
In this study, it was aimed to investigate the analgesic efficacy of the preoperatively applied Transversus Abdominis Plane (TAP) Block in the management of acute appendicitis-related abdominal pain and post-appendectomy pain.
- Conditions
- Acute Appendicitis, Acute Abdomen, Postoperative Pain
- Trial name
- NCT05004532
- Volunteers
- 22 people
- Sponsor
- Erol Olcok Corum Training and Research Hospital
the Effect of Instrumentation Kinematics on Intraoperative and Post-operative Pain
Effect of Instrumentation Kinematics on Intraoperative and Post-operative Pain in Maxillary Premolars With Acute Irreversible Pulpitis
Post-endodontic pain refers to the discomfort experienced following endodontic procedures. The incidence of post-operative pain is reported to be 25-40% regardless of the pulp and periradicular condition.
- Trial name
- Instrumentatio (NCT07250399)
- Testing
- EdgeOne Fire reciprocating system, JZ file system
- Where
- Egypt
- Volunteers
- 56 people
- Sponsor
- Al-Azhar University
Pain, Postoperative, Pain Uterus
Effects of Tapentadol Versus Oxycodone After Hysterectomy.
Opioids remain the first-line drugs for the treatment of moderate to severe postoperative pain, but the use is limited by well-known side-effects, most of which are dose-dependent.
- Conditions
- Pain, Postoperative, Pain Uterus, Pain, Acute, Opioid Use
- Trial name
- NCT03314792
- Testing
- Tapentadol, Oxycodone
- Where
- Norway
- Volunteers
- 86 people
- Sponsor
- Oslo University Hospital
Liver Neoplasms, Hepatic Resection
Erector Spinae Plane Block Versus Thoracic Epidural Analgesia for Open Liver Resection
Background: Open liver resection is associated with severe postoperative pain. While thoracic epidural analgesia (TEA) is considered the gold standard for pain control, its clinical application is often limited by postoperative…
- Conditions
- Liver Neoplasms, Hepatic Resection, Liver Cancer
- Trial name
- NCT07642336
- Testing
- Continuous Erector Spinae Plane block, Thoracic Epidural Analgesia (TEA)
- Where
- Vietnam
- Volunteers
- 60 people
- Sponsor
- Nguyen Toan Thang
Acute Pain
Study to Evaluate Analgesic Effect of Intravenous Administration of Kappa Agonist CR845 After Hysterectomy Surgery
The purpose of this study is to determine the effectiveness and safety of single intravenous doses of the kappa opioid agonist CR845 in relieving pain in patients following laparoscopic-assisted hysterectomy surgery.
- Trial name
- NCT00877799
- Testing
- CR845
- Where
- 12 sites in United States
- Volunteers
- 114 people
- Sponsor
- Cara Therapeutics, Inc.
Pain, Postoperative, Pain, Acute
A Study of the Effects of Intravenous Magnesium Sulphate on Anaesthesia and Analgesia in Elective General Surgery Patients
The aim of this double-blind randomized study will be to evaluate the effect an intravenous infusion of magnesium has on recovery outcomes after elective laparoscopic cholecystectomy
- Conditions
- Pain, Postoperative, Pain, Acute, Pain, Nociceptive, Analgesia
- Trial name
- NCT05598307
- Testing
- magnesium bolus followed by normal saline infusion, magnesium bolus followed by magnesium infusion, normal saline bolus followed by normal saline infusion
- Where
- Greece
- Volunteers
- 90 people
- Sponsor
- Aretaieion University Hospital
Acute Postoperative Pain, Non-steroidal Anti-inflammatory Drugs
Non-steroidal Anti-inflammatory in Cardiac Surgery
Non-steroidal anti-inflammatory drugs (NSAID) are part the multimodal strategy in pain management after surgery. However, major concerns are raised in cardiac surgery given the potential side effects of NSAID with more bleeding…
- Conditions
- Acute Postoperative Pain, Non-steroidal Anti-inflammatory Drugs, Cardiac Surgery, Pain Intensity
- Trial name
- KETOPAIN (NCT06381063)
- Testing
- pain management, ketoprofen
- Where
- France
- Volunteers
- 238 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Pain, Pain Postoperative
The Effects of Body Mass Index on Erector Spinae Plane Block Analgesia
In recent years, obesity has become one of the leading health problems worldwide. It is known that obesity can cause various diseases and negatively impact the quality of life.
- Conditions
- Pain, Pain Postoperative, Pain Acute, Erector Spinae Plane Block
- Trial name
- NCT06257953
- Testing
- Erector spinae plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Atatürk Chest Diseases and Chest Surgery Training and Research Hospital