Clinical trials: Acute Post-surgical Pain
Chronic Pain Following Surgical Procedure for Cancer
A Comparison of Gabapentin and Ketamine in Acute and Chronic Pain After Inguinal Hernia Repair
Patients were randomized into two groups: Group Gabapentine ( G group) received 600 mg of Gabapentin (two tablets) two hours prior to surgery and saline solution before induction of spinal anesthesia and group Ketamine ( K group)…
- Trial name
- NCT04700592
- Testing
- Gabapentin versus Ketamine
- Where
- Tunisia
- Volunteers
- 60 people
- Sponsor
- University Tunis El Manar
Postoperative Pain, Acute
Effect of Dexmedetomidine Versus Dexamethasone as Adjuvant to Bupivacaine in Ultrasound Guided Erector Spinae Plane Block on Postoperative Analgesia in Myasthenic Patients Undergoing Thoracoscopic Thymectomy
This current comparative study involved 54 patients undergoing thoracoscopic thymectomy who were distributed randomly into three equal groups to receive ultrasound (US)-guided ESPB using 20 ml bupivacaine 0.25% (group B) , 20 ml…
- Trial name
- NCT07424599
- Testing
- Erector Spinae Plane Block
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Pain, Postoperative, Pain, Acute
Comparison of Quadratus Lumborum Intramuscular and Transmuscular in Postoperative Pain
Acute pain is reported in approximately 80% of patients undergoing postoperative care for various types of surgical procedures in the United States.
- Conditions
- Pain, Postoperative, Pain, Acute, Cesarean Section Complications
- Trial name
- NCT05005871
- Testing
- Quadratus lumborum block after C-section surgery as postoperative pain management
- Where
- Indonesia
- Volunteers
- 48 people
- Sponsor
- Udayana University
Postoperative Pain, Acute, Postoperative Pain, Chronic
Application of Non-invasive Neurophysiological Methods in Predicting and Evaluating Postoperative Pain in Adult Patients Undergoing Major Thoracic Surgery
The primary aim of this study is to explore the relationship between alpha electroencephalographic oscillations, particularly Peak Alpha Frequency (PAF), pupillometry, intraoperative Nociception Level (NOL) and postoperative pain…
- Conditions
- Postoperative Pain, Acute, Postoperative Pain, Chronic, Postoperative Pain After Thoracic Surgery
- Trial name
- NCT06731010
- Where
- 2 sites in Greece
- Volunteers
- 20 people
- Sponsor
- National and Kapodistrian University of Athens
Acute Postoperative Pain, Chronic Postoperative Pain
Comparison of the Efficacy and Safety of Intravenous Buprenorphine Administered Via PCA System Versus Oxycodone in the Management of Postoperative Pain After Video-Assisted Thoracoscopic Surgery
The goal of this clinical trial is to learn whether intravenous buprenorphine administered via a patient-controlled analgesia (PCA) system provides effective and safer postoperative pain control than intravenous oxycodone PCA in…
- Conditions
- Acute Postoperative Pain, Chronic Postoperative Pain, Toracosurgery, Video-assisted Thoracis Surgery (VATS)
- Trial name
- NCT07434427
- Testing
- Group B (Buprenorphine), Group O (Oxycodone)
- Where
- Poland
- Volunteers
- 200 people
- Sponsor
- Medical University of Silesia
Benign Gynecological Disease
Predicting Acute Postoperative Pain by the Preoperative Lower Back Pain
To investigate if the level of preoperative lower back pain has the effect on the acute postoperative pain after gynecological laparoscopy
- Trial name
- NCT04793191
- Where
- South Korea
- Volunteers
- 150 people
- Sponsor
- The Catholic University of Korea
Breast Cancer
Efficacy of Thoracic Paravertebral Block in the Reduction of Acute Post-surgical Pain in Patients With Breast Cancer
Surgical treatment of breast cancer is frequently associated with postoperative pain in the surgical area. Persistent pain after breast cancer management has considerable negative effects on the quality of life of survivors.
- Trial name
- NCT02609321
- Testing
- Thoracic Paravertebral Block, Surgical Wound Infiltration
- Where
- Colombia
- Volunteers
- 60 people
- Sponsor
- Instituto de Cancerología S.A.
Hypertensive Disease, Pain, Postoperative
Effect of Acute Arterial Hypertension on Morphine's Requirements and Postsurgical Pain.
The purpose of this randomized clinical trial is to evaluate the effect of acute arterial hypertension maintained during surgery on morphine's requirements in patients undergoing laparoscopic cholecystectomy
- Trial name
- NCT01897155
- Testing
- SBP 20-30% over baseline, SBP 20-30% under baseline
- Where
- Chile
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidad Catolica de Chile
Cervical, Erector Spinae Plane Block
Cervical Erector Spinae Plane Block vs Cervical Plexus Block in Controlling Acute Postoperative Pain After Thyroidectomy
This study aims to compare the efficacy and safety of cervical erector spinae plane block vs. cervical plexus block in controlling acute postoperative pain after thyroidectomy.
- Conditions
- Cervical, Erector Spinae Plane Block, Cervical Plexus Block, Postoperative Pain
- Trial name
- NCT06974630
- Testing
- Cervical erector spinae plane block, Cervical plexus block
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Postoperative Pain, Acute
Comparison of Transversus Abdominis Plane and Erector Spinae Plane Blocks for Pain Control After Renal Laparoscopy
The goal of this study is to compare the analgesic efficacy of ultrasound-guided transversus abdominis plane (TAP) block versus erector spinae plane block (ESPB) in adult patients undergoing laparoscopic renal surgeries.
- Trial name
- TAP-ESPB (NCT07781930)
- Testing
- TAP Block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Knee Arthropathy
Persistent Post Surgical Pain After Total Knee Arthroplasty
Patients undergone total knee replacement are randomized to receive a "fast track" regional anesthesia protocol or a "traditional" regional anesthesia continuous infusion by both a femoral and sciatic catheter to assess if this…
- Trial name
- NCT06182059
- Testing
- continuous peripheral nerve block
- Where
- Italy
- Volunteers
- 436 people
- Sponsor
- Policlinico di Monza SpA
Anterior Cruciate Ligament Injury
Preemptive Analgesia in Cruciate Reconstruction
The aims of this study was to compare analgesic efficacy of preoperative administration of etoricoxib versus celecoxib for post-operative pain relief after arthroscopic anterior cruciate ligament reconstruction.
- Trial name
- NCT01017380
- Testing
- Celecoxib, etoricoxib
- Where
- Thailand
- Volunteers
- 30 people
- Sponsor
- Prince of Songkla University
Postoperative Pain, Acute
Pain Treatment With Combinations of NSAIDs
The search for new safe and effective methods of pain relief after surgery on large joints is still an urgent problem. The most optimal approach in the treatment of postoperative pain is the use of multimodal analgesia with a…
- Trial name
- NCT05994287
- Testing
- Aspirin, Ketorolac, Celecoxib
- Where
- Russia
- Volunteers
- 105 people
- Sponsor
- Federal State Budgetary Organization, Federal Center for Traumatology, Orthopedics and Arthroplasty
Phantom Limb Pain, Neuropathic Pain
Intrathecal Dexmedetomidine and Acute Neuropathic Pain After Lower Limb Amputation
This randomized controlled trial evaluated the effect of adding intrathecal dexmedetomidine (10 µg) to hyperbaric bupivacaine (11 mg) for spinal anesthesia in patients undergoing lower limb amputation.
- Conditions
- Phantom Limb Pain, Neuropathic Pain, Lower Limb Amputation
- Trial name
- DEX-RCT (NCT07565662)
- Testing
- Hyperbaric Bupivacaine plus Saline, Hyperbaric Bupivacaine plus Dexmedetomidine
- Where
- Mexico
- Volunteers
- 30 people
- Sponsor
- Universidad Juárez Autónoma de Tabasco
Post Operative Pain, Acute
Bupivacaine Alone vs Bupivacaine With Tramadol in Local Anesthesia Procedures
This study looked at two different medicines used during local anesthesia to control pain after surgery. Investigators compared bupivacaine alone with bupivacaine mixed with tramadol.
- Trial name
- NCT07469826
- Testing
- Tramadol, Bupivacaine
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Jinnah Postgraduate Medical Centre
Postoperative Pain, Postoperative Pain, Acute
Incidence of Chronic Pain After Video-Assisted Thoracic Surgery
Video-assisted thoracic surgery (VATS) is frequently performed in thoracic surgery. It is widely accepted that VATS causes acute pain.
- Conditions
- Postoperative Pain, Postoperative Pain, Acute, Postoperative Pain, Chronic, VATS
- Trial name
- NCT05187390
- Testing
- VATS application
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Atatürk Chest Diseases and Chest Surgery Training and Research Hospital
Pain, Postoperative
Caffeine Study for Pain Control Following Total Joint Replacement
A prospective, double blinded, single center, randomized controlled study to evaluate the efficacy of caffeine in combination with acetyl salicylic acid (ASA) in the management of postoperative pain in patients undergoing total…
- Trial name
- NCT04280263
- Testing
- Caffeine
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Rothman Institute Orthopaedics
Acute Postoperative Pain, Chronic Postoperative Pain
Menstrual Phase and Postoperative Pain
Fluctuations of female sex hormones during the menstrual cycle influence pain perception. Endogenous pain is pronounced in the follicular phase of the menstrual cycle.
- Trial name
- NCT02137135
- Testing
- HAD scale, The SF 12 test, Visual analogue score
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Necrotic Pulp, Acute Apical Periodontitis of Pulpal Origin
Clinical Efficacy of Novel Jasminum-based Calcium Hydroxide Medicament
A triple-blind, parallel group, randomized trial with an allocation ratio of 1:1. Participants randomly allocated into two groups A and B.
- Trial name
- NCT06653608
- Testing
- Nano-reinforced calcium hydroxide medicament, Calcium hydroxide without nanoparicles
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Pakistan Institute of Medical Sciences
Pain, Postoperative, Pain, Acute
Opioid-free Anesthesia in Laparoscopic Cholecystectomies
The aim of this study will be to investigate the effect of an opioid-free anesthesia regimen with a mixture of dexmedetomidine-lidocaine-ketamine in the same syringe versus fentanyl analgesia in elective laparoscopic…
- Conditions
- Pain, Postoperative, Pain, Acute, Pain, Chronic, Cholecystectomy
- Trial name
- NCT05089526
- Testing
- ketamine-lidocaine-dexmedetomidine, fentanyl
- Where
- Greece
- Volunteers
- 70 people
- Sponsor
- Aretaieion University Hospital