Clinical trials: Acute Postoperative Pain
Postoperative Pain
Preventive Analgesia With Anrikefon in Laparoscopic Cholecystectomy
This study will determine the optimal timing for Anrikefon administration. It will also assess the quality of patient recovery. Laparoscopic cholecystectomy (LC) is a routine surgical procedure.
- Trial name
- ANIPAP (NCT07566663)
- Testing
- Anrikefon for Preventive Analgesia, Anrikefon for bridging analgesia
- Where
- China
- Volunteers
- 274 people
- Sponsor
- Xuanwu Hospital, Beijing
Postoperative Pain, Acute, Postoperative Nausea and Vomiting
The Impact of Breath Exercise Training on Postoperative Pain, Anxiety, and Nausea-Vomiting in General Surgery Patients
This study was conducted to determine the effect of breath exercise on post-operative anxiety level, pain, and nausea-vomiting after general surgery. This was a randomized, controlled experimental study.
- Conditions
- Postoperative Pain, Acute, Postoperative Nausea and Vomiting, Patient Relations, Nurse
- Trial name
- NCT06546514
- Testing
- Breath Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 149 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Postoperative Pain, Analgesia
PENG Block Combined to Wound Infiltration for Hip Replacement
This study analyze the effect of Pericapsular Nerve Group (PENG) Block combined to wound infiltration for analgesia after elective hip replacement.
- Conditions
- Postoperative Pain, Analgesia, Hip Arthropathy, Acute Pain
- Trial name
- NCT04306133
- Testing
- PENG block, Wound Infiltration
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Campus Bio-Medico University
Thoracic Anesthesia, Thoracotomy
Opioid Consumption After Thoracotomy and Factors Affecting Postoperative Acute Pain
Thoracic surgery operations constitute a significant portion of surgical procedures performed in hospitals. In the United States, more than 50,000 thoracic surgical procedures are performed annually, and more than 80% of these…
- Conditions
- Thoracic Anesthesia, Thoracotomy, Opioid, Postoperative Pain Management
- Trial name
- NCT07329855
- Testing
- Opioid Analgesic, Pain Medicine
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- Ankara Ataturk Sanatorium Training and Research Hospital
Gynecologic Disease
the Effect of Dexmedetomidine and Licodaine on Acute Postoperative Pain in Gynecological Laparoscopy
The aim of this study is to investigate the effect of opioid-free anesthesia using dexmedetomidine and lidocaine instead of remifentanil infusion, on the acute postoperative pain after the gynecological laparoscopy
- Trial name
- NCT04906889
- Testing
- Dexmedetomidine Hydrochloride, Remifentanil Hydrochloride, Lidocaine Hydrochloride
- Where
- 2 sites in South Korea
- Sponsor
- The Catholic University of Korea
Post-operative Pain, Acute
To Compare the Skin Incision Made by the Electrocautery and Scalpel in Inguinal Hernia Repair
The Groin hernia repair is a commonly performed general surgery procedure in both adults and children with inguinal hernias constituting more than 95% of all groin hernia repairs.
- Trial name
- NCT05666973
- Testing
- Open Mesh Hernioplasty
- Volunteers
- 60 people
- Sponsor
- Tribhuvan University Teaching Hospital, Institute Of Medicine.
Pain, Postoperative, Multimodal Analgesia
Comparison of the Rhomboid Intercostal Block and Serratus Posterior Superior Intercostal Plane Block
Video-assisted thoracic surgery (VATS) is widely performed for the management of various thoracic pathologies and is generally associated with reduced surgical trauma compared with open thoracotomy.
- Conditions
- Pain, Postoperative, Multimodal Analgesia, Rhomboid Intercostal Block, Serratus Posterior Superior Intercostal Plane Block
- Trial name
- NCT07650877
- Testing
- Rhomboid Intercostal Block, Serratus Posterior Superior Intercostal Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Ankara City Hospital Bilkent
Pain, Acute
Evaluation of Pericapsular Nerve Group Block on Positioning Pain for Spinal Anesthesia in Hip Fracture Patients
The purpose of this study is to evaluate of analgesic effects of pericapsullar nerve group block which is performed preoperatively to assist positioning patients for performance of spinal anesthesia.
- Trial name
- NCT04871061
- Testing
- PENG Block, Conventional opioid analgesia (Fentanyl)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Cigli Regional Training Hospital
Postoperative Pain
The Ketamine for Acute Postoperative Analgesia (KAPA) Trial
Postoperative pain remains an important challenge for both patients and clinicians. Despite advances in pain management techniques, many patients continue to describe their pain as moderate to severe immediately after surgery.
- Trial name
- KAPA (NCT04646694)
- Testing
- Ketamine
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University Health Network, Toronto
Labor Pain, Pain, Postoperative
Spinal Analgesia as Fast Track Painless Labor
The purpose of this prospective, randomized, and controlled trial was to compare the efficacy of single-shot spinal analgesia to typical conventional treatments (continuous epidural analgesia and spinal-epidural combination) in…
- Conditions
- Labor Pain, Pain, Postoperative, Pain, Acute
- Trial name
- NCT05271760
- Testing
- Single-shot spinal analgesia, Continuous epidural analgesia, Combined spinal-epidural analgesia
- Where
- Saudi Arabia
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Prince Sattam Bin Abdulaziz University
Acute Post-operative Pain
Panda: Evaluation of a Smartphone-based Perioperative Pain Assessment Tool
This study will evaluate Panda, a smartphone-based pain assessment tool. During a child's recovery from surgery, a Post-Anesthetic Care Unit nurse will assess their pain, which helps determine what medication they need.
- Trial name
- Panda (NCT01610882)
- Testing
- Panda first followed by manual pain assessment, Manual first followed by Panda pain assessment
- Where
- Canada
- Volunteers
- 144 people
- Sponsor
- University of British Columbia
Post-operative Pain, Acute, Pain Threshold
Cold Press Test and Post Operative Pain Relationship
The goal of this clinical trial is to investigate whether it is possible to get a preliminary idea about the postoperative pain in the patient with the results of a practical cold press test applied to American Society of…
- Trial name
- NCT05904873
- Testing
- Mandibular Third Molar Surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sinem Büşra Kıraç Can
Phantom Limb Pain, Neuropathic Pain
Intrathecal Dexmedetomidine and Acute Neuropathic Pain After Lower Limb Amputation
This randomized controlled trial evaluated the effect of adding intrathecal dexmedetomidine (10 µg) to hyperbaric bupivacaine (11 mg) for spinal anesthesia in patients undergoing lower limb amputation.
- Conditions
- Phantom Limb Pain, Neuropathic Pain, Lower Limb Amputation
- Trial name
- DEX-RCT (NCT07565662)
- Testing
- Hyperbaric Bupivacaine plus Saline, Hyperbaric Bupivacaine plus Dexmedetomidine
- Where
- Mexico
- Volunteers
- 30 people
- Sponsor
- Universidad Juárez Autónoma de Tabasco
Pain, Postoperative, Liposomal Bupivacaine
Liposomal Bupivacaine Plus Plain Bupivacaine Versus Dexamethasone Plus Plain Bupivacaine in the Supraclavicular Brachial Plexus Block in Patients With Risk Factors for Severe Acute Postoperative Pain
The supraclavicular brachial plexus block (BPB) is a frequently used anaesthetic method for upper limb surgeries, including distal radial fracture surgery.
- Conditions
- Pain, Postoperative, Liposomal Bupivacaine, Dexamethasone, Supraclavicular Brachial Plexus Block
- Trial name
- NCT07665762
- Testing
- 10ml 0.5% plain bupivacaine with 10ml 1.33% liposomal bupivacaine, 19ml 0.5% plain bupivacaine with 1ml (4mg) dexamethasone
- Where
- Hong Kong
- Volunteers
- 90 people
- Sponsor
- The University of Hong Kong
Postoperative Pain, Adults
Safety and Efficacy Evaluation of S (+) - Ketamine in Adults
A multicenter, randomized, open-label, active controlled pragmatic clinical trial that evaluates the safety and efficacy of S (+) -ketamine for postoperative acute pain in adults in perioperative settings.
- Conditions
- Postoperative Pain, Adults, Anesthesia
- Trial name
- NCT04837170
- Testing
- Conventional therapy + S (+)-Ketamine, Conventional therapy
- Volunteers
- 12,000 people
- Sponsor
- Chinese PLA General Hospital
Postoperative Pain, Acute, Postoperative Pain, Chronic
Application of Non-invasive Neurophysiological Methods in Predicting and Evaluating Postoperative Pain in Adult Patients Undergoing Major Thoracic Surgery
The primary aim of this study is to explore the relationship between alpha electroencephalographic oscillations, particularly Peak Alpha Frequency (PAF), pupillometry, intraoperative Nociception Level (NOL) and postoperative pain…
- Conditions
- Postoperative Pain, Acute, Postoperative Pain, Chronic, Postoperative Pain After Thoracic Surgery
- Trial name
- NCT06731010
- Where
- 2 sites in Greece
- Volunteers
- 20 people
- Sponsor
- National and Kapodistrian University of Athens
Anesthesia, Postoperative Pain
Opioid-free Anesthesia and Acute Postoperative Pain
Control of intraoperative and postoperative pain with the use of opioids constitutes normal practice. Opioid free anesthesia (OFA) is a relatively recent anesthesiology practice according to which opioids are not administered…
- Conditions
- Anesthesia, Postoperative Pain, Cognitive Impairment, Variable
- Trial name
- NCT04976842
- Testing
- OFA, OBA
- Where
- Greece
- Volunteers
- 200 people
- Sponsor
- Attikon Hospital
Pain, Postoperative, Postoperative Pain, Acute
Impact of Preoperative Opioid-free Multimodal Analgesia on Time to Trial of Void in Ambulatory Urogynecologic Surgeries
This is a double-arm randomized control trial evaluating the impact of preoperative opioid-free analgesia on time to trial of void in ambulatory urogynecologic surgeries.
- Trial name
- NCT06379425
- Testing
- Acetaminophen, Celecoxib, Gabapentin
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Post Operative Pain, Acute, Irreversible Pulpitis
To Evaluate Post Operative Pain Using Two Different Kind of Sealers in Obturation of Teeth With Symptomatic Irreversible Pulpitis During Second Visit When the Patient is Painless
The goal of this randomized clinical trial is to evaluate pain after root canal treatment using two different kinds of sealers during obturation in 60 healthy , male and female patients ages between 18 to 40 years.
- Trial name
- NCT07266974
- Testing
- AH-Plus Epoxy Resin Sealer, bioceramic sealer
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Jaweria Gul Keyani
Post-operative Pain
IV Acetaminophen for Acute Post Operative Pain in C-Section Patients
Post-operative pain management after C-section is an important topic as the number of elective c-sections increases each year. Pain is managed either by giving opioids or by using non-opioids.
- Trial name
- NCT02069184
- Testing
- IV Acetaminophen
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Montefiore Medical Center