Clinical trials: Acute Renal Injury
Respiratory Distress Syndrome, Adult, Respiration, Artificial
PEEP-induced Changed in RRI as Physiological Background of Ventilator-induced Kidney Injury
The renal Doppler resistive index (RRI) is a noninvasive tool that has been used to assess renal perfusion in the intensive care unit (ICU) setting. Many parameters have been described as influential on the values of renal RI.
- Conditions
- Respiratory Distress Syndrome, Adult, Respiration, Artificial, Acute Kidney Injury
- Trial name
- PRE-VIKI (NCT03969914)
- Testing
- PEEP changes
- Where
- 2 sites in Italy
- Volunteers
- 105 people
- Sponsor
- Università degli Studi di Ferrara
Renal Cell Carcinoma (RCC), Renal Function Abnormal
Ischemic Preconditioning Reduces the Severity of Acute Kidney Injury After Partial Nephrectomy
It is demonstrated that remote ischemic preconditioning can alleviate the degree of acute renal injury on the operated side in patients undergoing partial nephrectomy.
- Trial name
- NCT07497958
- Testing
- Ischemic preconditioning, NO ischemic preconditioning
- Where
- China
- Volunteers
- 174 people
- Sponsor
- Sun Yat-sen University
Acute Kidney Failure
Immune Function in Acute Kidney Injury
The immune response to kidney damage during acute kidney injury (AKI) is an important contributor to the prolonged lack of renal function and progression of kidney injury.
- Trial name
- NCT02470507
- Testing
- AKI
- Where
- United Kingdom
- Volunteers
- 120 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Acute Kidney Injury, Severe Sepsis
Acute Kidney Injury in Septic Critically Ill Patients : Are Aminoglycosides Really Harmful?
The purpose of the present study is to determine whether administration of aminoglycosides in septic critically ill patient is a risk factor for acute kidney injury
- Trial name
- REAMICHOC (NCT01932814)
- Where
- France
- Volunteers
- 317 people
- Sponsor
- Université Victor Segalen Bordeaux 2
Early Acute Kidney Injury
Neutrophil Gelatinase-Associated Lipocalin: Biomarker of Acute Kidney Injury After Cardiac Surgery
The following objectives were used for comparison: 1)primary objective: Evaluate the urinary excretion of NGAL as a marker of early development of acute kidney injury in patients undergoing cardiac surgery.
- Trial name
- NCT00594919
- Where
- Brazil
- Volunteers
- 150 people
- Sponsor
- Hospital de Base
Acute Kidney Injury, Outcome, Fatal
Effect of Weekend Admission on Mortality Associated With Severe Acute Kidney Injury in England: a Propensity Score Matched, Population-based Study
Increased in-hospital mortality associated with weekend admission has been reported for many acute conditions, but no study has investigated "weekend effect" for acute kidney injury requiring dialysis (AKI-D).
- Trial name
- NCT02947698
- Volunteers
- 53,878 people
- Sponsor
- University Hospitals of Derby and Burton NHS Foundation Trust
Urinary Activin A in AKI
Urinary Activin A as Apredictive Marker for Assessement of Acute Kidney Injury Severity in Patient Admitted at Assuit University Hospital
Urinary Activin A as amarker for assessement of acute kidney injury severity in patient admitted at Assuit University Hospital
- Trial name
- NCT06188533
- Testing
- Urinary activin A in AKI
- Volunteers
- 70 people
- Sponsor
- Assiut University
Drug-induced Crystalline Nephropathy, Drug-induced Crystalluria
Drug-induced Crystalluria in Sulfamethoxazole, High Dose Ciprofloxacin and High Dose Amoxicillin
This study examines in hospitalized patients, treated with sulfamethoxazole, high dose ciprofloxacin or high dose iv amoxicillin, the incidence of drug-induced urinary crystal formation and its association with acute kidney…
- Conditions
- Drug-induced Crystalline Nephropathy, Drug-induced Crystalluria, Infections Treated With Sulfamethoxazole, High Dose Ciprofloxacin or High Dose iv Amoxicillin
- Trial name
- CRYSTALLINE (NCT07772752)
- Testing
- Crystalluria examination
- Where
- Belgium
- Volunteers
- 290 people
- Sponsor
- Universitair Ziekenhuis Brussel
Sepsis, Acute Kidney Injury Due to Sepsis
Renin Angiotensin Aldosterone System In Septic Kids
Prospective observational cohort study; pediatric sepsis vs. healthy pediatric subjects and pediatric sepsis with acute kidney injury (AKI) vs without AKI.
- Conditions
- Sepsis, Acute Kidney Injury Due to Sepsis, Acute Kidney Injury (Nontraumatic)
- Trial name
- RISK (NCT06295393)
- Where
- United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Ischemia Reperfusion Injury, Myocardial Injury
NAD+ Augmentation in Cardiac Surgery Associated Myocardial Injury Trial
A Randomized, Double-blind, placebo-controlled Trial to Evaluate the Efficacy of Oral Nam for the Prevention of Acute Kidney Injury in Patients Undergoing On-Pump Cardiac Surgery
- Conditions
- Ischemia Reperfusion Injury, Myocardial Injury, Acute Kidney Injury
- Trial name
- NACAM (NCT04750616)
- Testing
- Niacinamide
- Where
- United States
- Volunteers
- 331 people
- Sponsor
- Kaiser Permanente
Acute Kidney Injury
Serum MIF in Acute Kidney Injury
Acute kidney injury (AKI) is a common complication in critical care patients. Currently no parameters are available for early prognosis of AKI.
- Trial name
- NCT02352506
- Testing
- Blood draw for measurement of MIF
- Where
- Austria
- Volunteers
- 500 people
- Sponsor
- Medical University of Vienna
Postoperative Delirium, Acute Kidney Injury
Correlation Between Preoperative Sleep and Postoperative Brain and Renal Dysfunction
To explore the correlation between preoperative sleep parameter clustering and postoperative brain and renal dysfunction.
- Trial name
- NCT07518992
- Where
- China
- Volunteers
- 549 people
- Sponsor
- Xijing Hospital
Acute Kidney Injury, Anesthesia
The Effect of Propofol or Sevoflurane on Renal Function
This study investigates the role of the anesthetic agents propofol and sevoflurane on renal function in otherwise healthy patients undergoing basic back surgery.
- Trial name
- NCT03336801
- Testing
- Back Surgery, Propofol, Sevoflurane
- Where
- Sweden
- Volunteers
- 37 people
- Sponsor
- Uppsala University
Contrast-induced Acute Kidney Injury, ST Elevation Myocardial Infarction
A Randomized Trial of Rosuvastatin Loading Combined With Early hydrAtion Versus Standard-of-care Medications for the Prevention of CIAKI in Patient With AMI Undergoing Emergency PCI
The CIAKI,as the third complication of PCI, was associated with adverse cardiac events after procedure. Moreover, because the rate of periprocedure hydration is inadequate in STEMI patients before primary PCI, the incidence of…
- Conditions
- Contrast-induced Acute Kidney Injury, ST Elevation Myocardial Infarction, Primary PCI, Rosuvastatin
- Trial name
- TRACK-AMI (NCT03526367)
- Testing
- hydration plus rosuvastatin therapy, Standard therapy
- Where
- China
- Sponsor
- Shenyang Northern Hospital
Sepsis, Septic Shock
The Effect of Dexmedetomidine on the Renal Functions in Septic Critically Ill Patients
This clinical trial aims to evaluate the effect of dexmedetomidine in Sepsis-Associated Acute Kidney Injury in critically ill patients by answering the following questions: 1.
- Conditions
- Sepsis, Septic Shock, Acute Kidney Injury
- Trial name
- NCT06570187
- Testing
- Dexmedetomidine, Propofol
- Where
- Egypt
- Volunteers
- 128 people
- Sponsor
- Cairo University
Acute Kidney Injury
Care Bundle and Acute Kidney Injury Progression
The goal of this clinical interventional study is to learn about the effect of implementing a care bundle in the progression of acute kidney injury (AKI) in critical patients.
- Trial name
- NCT05597332
- Testing
- Care bundle for AKI
- Volunteers
- 400 people
- Sponsor
- University of Campinas, Brazil
Acute Kidney Injury, Fluid Overload
Restrictive Versus Liberal Rate of Extracorporeal Volume Removal Evaluation in Acute Kidney Injury
Critically ill patients with acute kidney injury and fluid overload who are frequently treated by fluid removal during dialysis are at an increased risk of complications and death.
- Conditions
- Acute Kidney Injury, Fluid Overload, Hypotension, Dialysis; Complications
- Trial name
- RELIEVE-AKI (NCT05306964)
- Testing
- Restrictive UFnet Rate Strategy, Liberal UFnet Rate Strategy
- Where
- 2 sites in United States
- Volunteers
- 99 people
- Sponsor
- University of Pittsburgh
Early Ventilator Associated Pneumonia, Acute Brain Injuries
PK/PD Target Attainment of Ceftriaxone for the Prevention of Early Ventilator-associated Pneumonia in Neurologically Injured Patients
Critically ill patients admitted for acute brain injury are exposed to many heath-care associated infections such as ventilator associated pneumoniae (VAP).
- Trial name
- NeuroPKVAP (NCT07450404)
- Where
- 2 sites in France
- Volunteers
- 60 people
- Sponsor
- Central Hospital, Nancy, France
Acute Kidney Injury
Prevention of Post-Cardiac Surgery Acute Kidney Injury by Proton Pump Inhibitor
The purpose of this study is to determine whether perioperative intravenous administration of pantoprazole will improve kidney function parameters following cardiac surgery with cardiopulmonary bypass compared to famotidine and…
- Trial name
- NCT06154226
- Testing
- Pantoprazole, Famotidine
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- The University of Texas Health Science Center, Houston
Patients Undergoing Valvular Heart Surgery
Relationship Between Postoperative Tempeartive and Acute Kidney Injury
The investigators aimed to identify body temperature trajectory classes based on core temperature changes during the first 12 hours post-surgery and to explore their relationship with postoperative acute kidney injury in patients…
- Trial name
- NCT06647771
- Where
- South Korea
- Volunteers
- 3,274 people
- Sponsor
- Yonsei University