Clinical trials: Acute Respiratory Viral Infections
Corona Virus Infection, Acute Respiratory Distress Syndrome
Post-exposure Prophylaxis / Preemptive Therapy for SARS-Coronavirus-2
Study Objective: 1. To test if post-exposure prophylaxis with hydroxychloroquine can prevent symptomatic COVID-19 disease after known exposure to the SARS-CoV-2 coronavirus. 2.
- Conditions
- Corona Virus Infection, Acute Respiratory Distress Syndrome, SARS-CoV Infection, Coronavirus
- Trial name
- COVID-19 PEP (NCT04308668)
- Testing
- Hydroxychloroquine
- Where
- 5 sites in United States, Canada
- Volunteers
- 1,312 people
- Sponsor
- University of Minnesota
Covid19, Stress, Psychological
Psychological Impact of COVID-19 Pandemic in Healthcare Workers
Background. The current coronavirus disease (COVID-19) has a great impact worldwide. Healthcare workers play an essential role and are one of the most exposed groups.Information about the psychosocial impact on healthcare workers…
- Conditions
- Covid19, Stress, Psychological, Work Related Stress, Epidemic Disease
- Trial name
- PSIMCOV (NCT04506515)
- Testing
- Psychological stress and adaptation at work score (PSAS)
- Where
- Spain
- Volunteers
- 3,000 people
- Sponsor
- Hospital General Universitario de Valencia
SARS-CoV, Nutrition Disorders
Nutritional Assessment of Hospitalized Patients With COVID-19
The nutritional consequences of the infection by the SARS-CoV-2 are as follows: A severe respiratory infection induces an inflammatory syndrome and hypercatabolism, as well as an increase in energy expenditure related to…
- Trial name
- DenutCOVID (NCT04503525)
- Testing
- Nutritional assessment
- Where
- France
- Volunteers
- 90 people
- Sponsor
- Lille Catholic University
Covid19, SARS-CoV Infection
Collection of the Thrombo-VaxCov Cohort
In the context of anti-Covid19 vaccination, atypical thrombosis have occured and potential link with vaccination is under investigation.
- Conditions
- Covid19, SARS-CoV Infection, Venous Thrombosis, Thrombocytopenia
- Trial name
- THROMBO-VAXCOV (NCT04889326)
- Testing
- Retrospective data and biological samples
- Where
- France
- Sponsor
- University Hospital, Lille
COVID-19, Severe Acute Respiratory Syndrome Coronavirus 2
Monocytes and NK Cells Activity in Covid-19 Patients
SARS-CoV-2 belong to beta-coronavirus family and its transmission route and symptoms follow those of all community-acquired coronaviruses.
- Conditions
- COVID-19, Severe Acute Respiratory Syndrome Coronavirus 2, Immunomodulation
- Trial name
- NCT04375176
- Testing
- Study of immune-mediated mechanisms in patients tested positive for SARS-CoV-2
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- Università degli Studi dell'Insubria
Acute Bronchiolitis
FeNO and Cytokines in Respiratory Syncytial Virus (RSV) and Non RSV Bronchiolitis in Relation to Future Asthma
The purpose of this study is to determine Fractional exhaled Nitric-Oxide (FeNO)levels and blood cytokines during acute bronchiolitis, and to seek for correlation between these markers and future development of asthma.
- Trial name
- NCT02093715
- Where
- Israel
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
PASC Post Acute Sequelae of COVID 19
Physiological and QoL Benefits of Qi-Gong in Post-acute Sequelae of Covid-19
The goal of this clinical trial is to determine whether Qi-Gong can improve physiological function and quality of life (QoL) in individuals with post-acute sequelae of SARS-CoV-2 infection (PASC).
- Trial name
- QG-PASC (NCT06879925)
- Testing
- QI-GONG and control
- Where
- 2 sites in Taiwan
- Volunteers
- 80 people
- Sponsor
- POCHIWU
Immune and Microbial Reconstitution, Systemic Viral Infection
Monitoring of Immune and Microbial Reconstitution in (HCT) and Novel Immunotherapies
This protocol serves as a mechanism to collect, store, and distribute bodily fluid and tissue samples obtained from Hematopoietic Cell Transplant (HCT) or novel immunotherapy patients and their donors at the Masonic Cancer Center…
- Conditions
- Immune and Microbial Reconstitution, Systemic Viral Infection, Acute-graft-versus-host Disease, Chronic Graft-versus-host-disease
- Trial name
- NCT03557749
- Testing
- Blood Sample, Stool Sample, Urine Sample
- Where
- United States
- Volunteers
- 210 people
- Sponsor
- Masonic Cancer Center, University of Minnesota
Covid19, Post-COVID / Long-COVID
Post-coronavirus Disease-2019 Fatigue
Background: COVID-19 is consistently spreading throughout the world, and the number of recovered patients is steadily increasing.
- Trial name
- NCT04851561
- Testing
- Cardiopulmonary stress test (CPET)
- Where
- Israel
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Rabin Medical Center
Post-COVID-19 Syndrome, Long-COVID-19 Syndrome
Fat Oxidation Capacity in Patients With Post Covid-19 Syndrome
Post-COVID-19 Syndrome (PCS) is characterized by symptoms, including fatigue, reduced physical performance, dyspnea, cognitive impairment, and psychological distress.
- Trial name
- NCT06468722
- Testing
- Exercise-based rehabilitation
- Where
- Germany
- Volunteers
- 187 people
- Sponsor
- University of Witten/Herdecke
Mild to Moderate COVID-19
Evaluate the Efficacy and Safety of FB2001 for Inhalation in Patients With Mild to Moderate COVID-19
This study is a double-blind,randomized,placebo-controlled study to evaluate the efficacy and safety of FB2001 for Inhalation in patients with mild to moderate Coronavirus Disease 2019(COVID-19).
- Trial name
- NCT05675072
- Testing
- FB2001
- Where
- China
- Volunteers
- 1,336 people
- Sponsor
- Frontier Biotechnologies Inc.
Bone Marrow Transplant Infection, Infection in Marrow Transplant Recipients
Respiratory Syncytial Virus - RSV Protocol
The goal of this clinical research study is to learn if ribavirin can help to control RSV in patients with immune systems that have been weakened by a stem cell transplant.
- Conditions
- Bone Marrow Transplant Infection, Infection in Marrow Transplant Recipients, Respiratory Syncytial Virus Infections, Respiratory Syncytial Virus Pneumonia
- Trial name
- NCT01502072
- Testing
- Ribavirin
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- M.D. Anderson Cancer Center
Persistent COVID Condition
Predictors of Long-Term Evolution in Long COVID; 4-Year Follow-Up. (BioICOPER Follow-up Study)
Long COVID (persistent COVID) represents a major global health challenge due to its high prevalence (approximately 7%), significant impact on quality of life, and socioeconomic burden.
- Trial name
- NCT07295483
- Testing
- BioICOPER Long COVID Cohort
- Where
- Spain
- Volunteers
- 400 people
- Sponsor
- Instituto de Investigación Biomédica de Salamanca
SARS-CoV Infection
Electrocardiogram Analysis in COVID-19 Patients
Electrocardiographic (ECG) evaluation of patients with severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2) infection. The present study involves three different phases of evaluation of the ECG traces of hospitalized…
- Trial name
- ELCOVID (NCT04367129)
- Testing
- ECG
- Where
- Italy
- Volunteers
- 1,014 people
- Sponsor
- University Hospital of Ferrara
COVID-19
Disability Following Hospitalization in People of Working-age Surviving SARS-CoV-2 Infection - COVID-19
The purpose of the study is to describe disability following hospitalization in people of working-age surviving COVID-19.
- Trial name
- DisCOVID (NCT04724395)
- Testing
- Hospitalization
- Where
- France
- Volunteers
- 530 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
ARDS
MultiStem Administration for COVID-19 Induced ARDS (MACoVIA)
Multicenter investigation featuring an open-label lead-in followed by a double blinded, randomized, placebo-controlled Phase 2/3 part to evaluate the safety and efficacy of MultiStem therapy in subjects with moderate to severe…
- Trial name
- MACoVIA (NCT04367077)
- Testing
- MultiStem
- Where
- 4 sites in United States
- Volunteers
- 22 people
- Sponsor
- Healios K.K.
Oxygen Deficiency, Coronavirus Infection
Awake Proning in COVID-19 Patients With Hypoxemic Respiratory Failure
The purpose of this study is to retrospectively review clinical data to determine whether awake proning improves oxygenation in spontaneously breathing patients with COVID-19 severe hypoxemic respiratory failure.
- Trial name
- NCT04408222
- Testing
- Awake proning
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Columbia University
Covid19, Telogen Effluvium
COVID-19 Induced Telogen Effluvium
This study inquires about the development of Telogen effluvium following the SARS-CoV-2 infection
- Conditions
- Covid19, Telogen Effluvium, SARS-CoV Infection, Alopecia
- Trial name
- NCT04834102
- Testing
- Blood Tests
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Istanbul Medeniyet University
Respiratory Viral Infection, Covid19
Reducing Acute Severe Respiratory Events in Health Care Workers During the Covid-19 Pandemic With OM85
Parallel group, Wait-list design, with treatment delayed for 3 months. Participants will be randomized on a 1:1 ratio with 500 participants per group in Australia. Group 1: Wait-list control.
- Trial name
- COVIDRASP (NCT04496245)
- Testing
- Broncho-Vaxom®
- Where
- 3 sites in Australia
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- The University of Queensland
Coronary Artery Disease, Congestive Heart Failure
Prognostic Indicators as Provided by the EPIC ClearView
The objective of this study is to determine whether the finger tip images captured by the EPIC ClearView device, when analyzed via the ClearView software, produce a Response Scale that characterizes trends consistent with known…
- Conditions
- Coronary Artery Disease, Congestive Heart Failure, Valvular Heart Disease, Atrial Fibrillation
- Trial name
- GBMC (NCT01476995)
- Where
- United States
- Volunteers
- 353 people, healthy volunteers welcome
- Sponsor
- Epic Research & Diagnostics, Inc.