Clinical trials: Acute Rhinitis
Upper Respiratory Tract Infection, Nasal Congestion
Evaluation of Efficacy and Safety of Tablets of Paracetamol, Dimethindene Maleate and Phenylephrine Hydrochloride in Reducing Symptoms of Common Cold and Flu
The study is a clinical evaluation of an over the counter (OTC) combination product containing paracetamol (500 mg), dimethindene maleate (1 mg), phenylephrine hydrochloride (10 mg) compared to paracetamol (500 mg) alone in the…
- Conditions
- Upper Respiratory Tract Infection, Nasal Congestion, Rhinorrhea, Sneezing
- Trial name
- NCT01448057
- Testing
- Paracetamol (500 mg)/dimethindene maleate (1 mg)/ phenylephrine hydrochloride (10 mg) tablets, Paracetamol (500 mg) tablets
- Where
- 6 sites in Brazil
- Volunteers
- 341 people
- Sponsor
- Novartis
Common Cold, Infections, Upper Respiratory Tract
Acute Cough Study In Children
15 mg dextromethorphan hydrobromide will be better than placebo with respect to reducing the number of coughs over 6 hours and reducing the subjective severity of cough over 6 hours.
- Trial name
- NCT01257542
- Testing
- Dextromethorphan
- Where
- 4 sites in United States
- Volunteers
- 140 people
- Sponsor
- Pfizer
Acute Respiratory Infection
University of Wisconsin Meditation & Exercise Cold Study
The primary goal of this project is to determine whether behavioral training in mindfulness meditation or moderate intensity sustained exercise will lead to reductions in acute respiratory infection (ARI) illness, such as common…
- Trial name
- MEPARI-2 (NCT01654289)
- Testing
- Mindfulness Meditation, Exercise
- Where
- United States
- Volunteers
- 413 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Common Cold
Testing the Efficacy in Adults With Cold of HEalsea Rescue*
Healsea® Rescue* is a CE-marked class I medical device. This is a saline-based nasal spray supplemented with a natural Symbiofilm™ extract (0.04%) isolated from the marine bacteria.
- Trial name
- TEACHER (NCT05819190)
- Testing
- Healsea Rescue*
- Where
- Bulgaria
- Volunteers
- 200 people
- Sponsor
- Lallemand Pharma AG
Acute Respiratory Infections, Acute Rhinosinusitis
Treatment of Acute Sinusitis
This study will compare the symptom relief provided by 5 cold medicines versus the symptom relief provided by the same 5 cold medicines plus the antibiotic, amoxicillin, in people who have sinus infections.
- Trial name
- NCT00377403
- Testing
- Acetaminophen, Amoxicillin, Dextromethorphan hydrobromide with guaifenesin
- Where
- United States
- Volunteers
- 172 people
- Sponsor
- Washington University School of Medicine
Upper Respiratory Infection, Common Cold
The Natural History of Viral Upper Respiratory Infections in Children Aged 6 to Less Than 14 Years
This study examines the cold processes of children aged 6 to less than 14. Children will be seen by the study staff 6 days in a row during the course of their naturally-acquired colds.
- Trial name
- NCT00405509
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- West Penn Allegheny Health System
Otitis Media
Effect of Simethicone on Eustachian Tube Dysfunction
This study is designed to measure the effects of a chewable Simethicone tablet taken by mouth on middle-ear pressure in adults with a common cold and evidence of abnormal middle-ear pressure.
- Trial name
- NCT01312038
- Testing
- Simethicone
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Pittsburgh
Vasomotor Rhinitis
Efficacy of Esomeprazole for Non-Allergic Rhinitis: A Double-blind, Placebo Controlled Trial
The purpose of this study was to see if high dose esomeprazole (40mg bid) was effective in treating non-allergic rhinitis
- Trial name
- NCT00745849
- Testing
- esomeprazole
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- University of Texas Southwestern Medical Center
Common Cold
Warming Sensation and Tolerability Study of Acetylcysteine 2% Oral Solution for Productive Cough
This is a 1-treatment arm, open label design. This 1-day study includes a screening on day of attendance at clinic, followed by a washout period of 30 minutes to 8 hours (if participants are eligible for dosing the same day).
- Trial name
- NCT02822287
- Testing
- Acetylcystine
- Where
- Germany
- Volunteers
- 58 people
- Sponsor
- GlaxoSmithKline
Rhinitis
Treatment With Rhinospray Plus in Patients With Acute Rhinitis in the Everyday Curative Routine in Hungary
Multi-centre, open-label, prospective, uncontrolled, single-arm, non-interventional study (NIS) with objective to collect and evaluate data concerning treatment with Rhinospray Plus in everyday curative routine treatment of acute…
- Trial name
- NCT01971086
- Where
- 4 sites in Hungary
- Volunteers
- 300 people
- Sponsor
- Boehringer Ingelheim
Common Cold
Iota-Carrageenan Nasal Spray in Common Cold
The aim of this clinical trial is to investigate the effect of Iota-Carrageenan treatment on cold symptoms. The effect of treatment on the duration of the cold and the patients viral load plus cytokine level indicating the…
- Trial name
- NCT01944631
- Testing
- Iota-Carrageenan
- Where
- United Kingdom
- Volunteers
- 200 people
- Sponsor
- Boehringer Ingelheim
Vasomotor Rhinitis
Nasal Physiologic Reactivity of Nonallergic Rhinitics to Cold Air Provocation
This study seeks to compare patients with vasomotor rhinitis ("perennial nonallergic rhinitis," "idiopathic rhinitis") with normal controls with respect to their nasal physiologic reactivity to cold air challenge.
- Trial name
- NCT00415493
- Testing
- Cold-dry air provocation, Warm-moist air provocation
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Associated Scientists to Help Minimize Allergies
Rhinitis
SB705498 Proof of Concept Chamber Challenge in Subjects With Non Allergic Rhinitis
The purpose of this study is to assess the pharmacodynamic (PD) effects (Total Symptom Score (TSS) and its individual components: rhinorrhoea, nasal congestion, post-nasal drip) of intranasal, repeat dose SB-705498 in…
- Trial name
- NCT01424514
- Testing
- SB-705498
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- GlaxoSmithKline
Sore Throat Due to a Common Cold
Efficacy and Safety of a Sore Throat Lozenge Containing Lidocaine and Cetylpyridinium Chloride in Patients With Sore Throat Due to a Common Cold.
This study will compare the efficacy and safety of a single dose of a lidocaine 8 mg + cetylpyridimium chloride (CPC) 2 mg lozenge with a single dose of a lidocaine 1 mg + CPC 2 mg lozenge in the treatment of sore throat due to a…
- Trial name
- NCT01265446
- Testing
- Lidocaine 8mg + CPC 2mg, Lidocaine 1mg + CPC 2mg
- Where
- Germany
- Volunteers
- 250 people
- Sponsor
- Novartis
Common Cold
A Nasal Spray With Glucose Oxidase as a Treatment of Common Cold
Healthy persons are invited to participate in the study and are given a home protocol (WURSS21), nasal spray and a sample pin. The included persons are told to make a nasopharyngeal sampling from the nose when they are sure that…
- Trial name
- NCT01883453
- Testing
- Glucose oxidase+5%glucose, Saline+5%glucose
- Where
- 2 sites in Sweden
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Umeå University
Rhinitis, Allergic, Seasonal
Study of a Topical Nasal Spray to Ease the Symptoms of Hayfever
The purpose of this study is to see if a new nasal spray can reduce the signs and symptoms of allergic rhinitis (hayfever). Subjects' participation in the study will last approximately 4 to 6 weeks, and each of three study visits…
- Trial name
- NCT01500629
- Testing
- C-1266-7
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- McNeil Consumer Healthcare Division of McNEIL-PPC, Inc.
Common Cold
Otrivine: Quality of Life (QoL) Impact in a Real-World Setting
This study is designed to generate real world data from participants with nasal congestion acquired from common cold following treatment with a marketed nasal spray.
- Trial name
- NCT05556148
- Testing
- Otrivine Congestion Relief
- Where
- United Kingdom
- Volunteers
- 136 people
- Sponsor
- HALEON
Rhinosinusitis
Efficacy and Safety of Acetylcysteine for the Treatment of Acute Uncomplicated Rhinosinusitis
The trial was conducted as a prospective, randomized, multinational, multicenter, double-blind study in 4 parallel groups of patients.
- Trial name
- NCT04123405
- Testing
- acetylcysteine
- Where
- 37 sites in Bulgaria, Germany and 2 more
- Volunteers
- 944 people
- Sponsor
- Sandoz
Common Cold
To Evaluate the Efficacy and Safety of 1146A Nasal Spray in Adult Participants With Symptoms of Common Cold
This study will be conducted in adult participants with symptoms of common cold assessing if 1146A nasal spray reduces the severity of symptoms of the common cold compared to placebo.
- Trial name
- NCT03005067
- Testing
- Carbomer 980 (1146A)
- Where
- 24 sites in United States
- Volunteers
- 171 people
- Sponsor
- GlaxoSmithKline
Rhinitis, Allergic, Perennial
A Pilot Study In Adults And Adolescents With Irritant (Non-Allergic) Rhinitis
The purpose of this pilot study is to compare the effects (effectiveness and safety)of an intranasal corticosteroid (fluticasone furoate nasal spray [FFNS]) with a placebo nasal spray for the treatment of irritant (non-allergic)…
- Trial name
- NCT00730756
- Testing
- Fluticasone Furoate Nasal Spray
- Where
- 5 sites in Thailand
- Volunteers
- 102 people
- Sponsor
- GlaxoSmithKline