Clinical trials: Acute Sinusitis, active
Rhinosinusitis, Rhinosinusitis Acute
The Efficacy and Safety of Raphamin in the Treatment of Acute Rhinosinusitis in Adult Patients
Multicenter double-blind placebo-controlled randomized in parallel groups clinical trial of the efficacy and safety of Raphamin in the treatment of acute rhinosinusitis in adult patients.
- Trial name
- NCT06901297
- Testing
- Raphamin
- Where
- 44 sites in Russia
- Volunteers
- 552 people
- Sponsor
- Materia Medica Holding
Rhinitis Acute, Rhinitis Viral
RhinAV_Evaluation of Treatments for Acute Viral Rhinitis, Rhinosinusitis, and Rhinopharyngitis
The objective of this study is to conduct post-marketing clinical follow-up of four products: NS, NHE, NHG, and PIR. This follow-up will consist of collecting clinical data in real-life conditions to confirm the tolerance…
- Conditions
- Rhinitis Acute, Rhinitis Viral, Rhinosinusitis Acute, Rhinopharyngitis
- Trial name
- RhinAV (NCT07383493)
- Testing
- PIR, NS, NHE
- Where
- France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Clermont-Ferrand
Chronic Sinusitis, Acute Sinusitis
Efficacy of Bee Venom Phonophoresis in Treating Chronic Sinusitis:
This double-blind, randomized controlled trial (BEE-SONIC) aims to evaluate the efficacy of bee venom phonophoresis in the treatment of chronic sinusitis.
- Conditions
- Chronic Sinusitis, Acute Sinusitis, Rhinosinusitis
- Trial name
- BEE-SONIC (NCT07151313)
- Testing
- Bee Venom Phonophoresis, Standard Care (oral decongestants + saline nasal irrigation)
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Sinai University
Acute Rhinitis, Nasal Obstruction
Performance and Safety Assessment of the Mechanical Decongestant Seawater Spray Enriched With Essential Oils From Laboratoires Gilbert in Patient With Acute Rhinitis Associated With Nasal Obstruction
The purpose of this post-market clinical investigation is to assess the performance and the safety of the mechanical decongestant seawater spray enriched with essential oils from Laboratoires Gilbert.
- Conditions
- Acute Rhinitis, Nasal Obstruction, Rhinosinusitis, Rhinopharyngitis
- Trial name
- DEMECA (NCT06580210)
- Where
- 3 sites in France
- Volunteers
- 114 people
- Sponsor
- Laboratoires Gilbert
Chronic Rhinosinusitis Without Polyps
Thermosensitive Gel Nasal Spray With Exosomes, Azelastine, and Interferon for Acute Phase of Chronic Sinusitis
This study tests a new nasal spray for adults (18-65 years) with chronic sinusitis experiencing an acute phase. The spray contains a temperature-sensitive gel that turns into a soft gel inside the nose to slowly release three…
- Trial name
- CRS (NCT07635459)
- Testing
- Exosomes, Azelastine, and Interferon alpha-2b, Azelastine and Interferon alpha-2b
- Volunteers
- 108 people
- Sponsor
- The First Affiliated Hospital of Xinxiang Medical College
Acute Rhinitis, Nasal Obstruction
Safety and Performance Assessment of the Decongestant Seawater Spray Pocket Valve Enriched With Essential Oils in Patients With Acute Rhinitis Associated With Nasal Obstruction: "DEVALPO"
The purpose of this pre-market clinical investigation is to assess the safety and the performance of decongestant seawater spray pocket valve enriched with essential oils by Gilbert Laboratories.
- Conditions
- Acute Rhinitis, Nasal Obstruction, Rhinosinusitis, Rhinopharyngitis
- Trial name
- DEVALPO (NCT05494346)
- Testing
- Measurement of peak nasal flow.
- Where
- 5 sites in France
- Volunteers
- 101 people
- Sponsor
- Laboratoires Gilbert
Nasal Obstruction, Common Cold
Observational Study of RHINOSEDAL in Acute Nasal Obstruction
This prospective, multicenter, national, observational, non-interventional post-market clinical follow-up study evaluates the performance and safety of RHINOSEDAL in children and adults presenting with acute nasal obstruction…
- Conditions
- Nasal Obstruction, Common Cold, Allergic Rhinitis, Non-allergic Rhinitis
- Trial name
- RHINOSEDAL (NCT07620522)
- Testing
- RHINOSEDAL
- Where
- France
- Volunteers
- 126 people
- Sponsor
- Laboratoires Elerte
Sinus Infection, Acute Sinusitis
Nasal Steroids, Irrigation, Oral Antibiotics, and Subgroup Targeting for Effective Management of Acute Sinusitis
Sinus infections (also called acute rhinosinusitis or ARS) affect about 15% of adults each year, and are one of the top reasons people receive antibiotics in outpatient settings.
- Trial name
- NOSES (NCT06076304)
- Testing
- amoxicillin/clavulanate potassium, Budesonide nasal spray
- Where
- 7 sites in United States
- Volunteers
- 3,720 people
- Sponsor
- Daniel Merenstein
Angina, Acute Bronchiolitis
Impact of a Multimodal Intervention on Antibiotic Prescribing for Respiratory Infections in Primary Care
Antimicrobial resistance (AMR), considered one of the greatest global threats by the WHO, justifies the development of initiatives to promote appropriate antibiotic use-especially in primary care, where most antibiotics in France…
- Conditions
- Angina, Acute Bronchiolitis, Acute Bronchitis, COPD Exacerbation (AECOPD)
- Trial name
- GRASP (NCT07359287)
- Testing
- Antibiotic prescribing according to guidelines
- Where
- France
- Volunteers
- 4,500 people
- Sponsor
- University Hospital, Caen
ACUTE SINUSITIS, Sinusitis
Comparative Effectiveness of Available Treatments for Sinus and Ear Infections in Children (Acute Sinusitis)
This study is being conducted at multiple hospitals and clinics to better understand whether antibiotics truly help children feel better when they have a sinus infection (acute sinusitis).
- Trial name
- MEASURE (NCT07732699)
- Testing
- Amoxicillin, Amoxi Clavulanate
- Where
- 5 sites in United States
- Volunteers
- 1,100 people
- Sponsor
- Nader Shaikh
Tonsillitis Acute, Pneumonia - Bacterial
Comparative Study of Adherence to Antibiotic Therapy Among Pediatric Patients: Hospital Emergency Department vs. Primary Care Center
This study was initiated because of the limited litterature available on this topic. The objective was to compare adherence to antibiotic therapy among a pediatric population treated in two healthcare settings in France: the…
- Conditions
- Tonsillitis Acute, Pneumonia - Bacterial, Otitis Media Acute, Cystitis Acute
- Trial name
- ObsATBGignaUrg (NCT07711756)
- Volunteers
- 191 people
- Sponsor
- University Hospital, Montpellier
Acute Bronchitis, ACUTE SINUSITIS
Improving Patient-centered Communication and Antibiotic Use With Information Sheets for Acute Respiratory Tract Infections: A Study Protocol
The goal of this trial is to investigate if the use of information sheets regarding acute respiratory tract infections will lead to more rational antibiotic prescribing and increase patient-centered communication i Danish general…
- Conditions
- Acute Bronchitis, ACUTE SINUSITIS, Sore Throat
- Trial name
- NCT07383350
- Testing
- ARTI Info-sheets
- Where
- Denmark
- Volunteers
- 1,144 people
- Sponsor
- Research Unit for General Practice in Aalborg
Community Acquired Pneumonia (CAP), Sinusitis
Reducing Antibiotic Use by Implementation of Stewardship in Primary and Urgent Care
The goal of this project is to reduce unnecessary antibiotic use for children with ARTIs (Acute Respiratory Tract Infections) by implementing "outpatient antibiotic stewardship" across the Children's Hospital of Philadelphia…
- Conditions
- Community Acquired Pneumonia (CAP), Sinusitis, Strep Pharyngitis, Acute Otitis Media (AOM)
- Trial name
- RAISIN (NCT07217002)
- Testing
- Online Educational Modules, Prescribing Feedback Reports, Clinical Decision Support
- Where
- United States
- Volunteers
- 420 people
- Sponsor
- Children's Hospital of Philadelphia