Clinical trials: Acute Stroke, open to volunteers
Fatty Liver, Acute Ischemic Cerebral Stroke
Burden Fatty Liver Among Acute Ischemic Cerebral Stroke Patients
1. Assess frequency of hepatic steatosis among patients in patients with Ischemic stroke without previous risk factors 2. Assess outcomes morbidity and mortality ischemic stroke in correlation with hepatic steatosis .
- Trial name
- NCT06628700
- Volunteers
- 97 people
- Sponsor
- Assiut University
Acute Ischemic Stroke
The Intensive Care Bundle with Mortality Reduction in Acute Ischemic Stroke Trial
Ischemic stroke, also known as cerebral infarction, accounts for as high as 60% to 80% of all stroke cases, and it is characterized by high morbidity, high disability rate, and high mortality rate.
- Trial name
- ICB-MRAIS (NCT06628817)
- Testing
- The Intensive Care Bundle with Mortality Reduction
- Volunteers
- 55,000 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Acute Ischemic Stroke
Safety and Efficacy of Levofloxacin Combined With Intravenous Thrombolysis for Acute Ischemic Stroke
The purpose of this study is to determine the efficacy and safety of levofloxacin combined with intravenous thrombolysis in treating acute ischemic stroke
- Trial name
- NCT05741905
- Testing
- Levofloxacin, Levofloxacin simulant
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Yi Yang
Acute Ischemic Stroke
Safety and Efficacy of Levofloxacin for Acute Ischemic Stroke
The purpose of this study is to determine the efficacy and safety of levofloxacin in treating acute ischemic stroke.
- Trial name
- NCT05799326
- Testing
- Levofloxacin, Levofloxacin simulant
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Yi Yang
Ischemic Cerebrovascular Disease, Acute Ischemic Stroke
Efficacy and Safety of Calculus Bovis Sativus (CBS) for Ischemic Cerebral Vascular Disease (CBSinICVD)
The most common cause of death for Chinese patients is ischemic cerebrovascular diseases(ICVD), particularly cerebral infarction.
- Conditions
- Ischemic Cerebrovascular Disease, Acute Ischemic Stroke, Cerebral Small Vessel Diseases
- Trial name
- NCT06474507
- Testing
- Calculus bovis sativus (CBS)
- Where
- 2 sites in China
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Tongji Hospital
Ischemic Stroke, Acute
A Multicenter Study Based on Multi-omics Analysis to Predict the Early Prognosis and Recurrence Risk of Acute Ischemic Stroke
Through a multicenter prospective AIS cohort study, we analyze the potential association of human proteome, microbiome and metabolome alterations with AIS prognosis, searching for key proteins, differential organisms and…
- Trial name
- NCT06584565
- Testing
- microbiome; metabolomics; proteomics
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Acute Ischemic Stroke
Predictive Role of sTREM in Endovascular Thrombectomy Outcomes
Soluble triggering receptor expressed on myeloid cells (sTREM), which reflects microglia activation, has been reported closely associated with neuronal injury and neuroinflammation.
- Trial name
- NCT06545591
- Where
- China
- Volunteers
- 300 people
- Sponsor
- The Affiliated Hospital of Xuzhou Medical University
Acute Ischemic Stroke
Prognostic Prediction Model of Patients With AcUte Stroke undeRgoing EndOvascular TheRApy (AURORA)
Stroke is the leading cause of disability-adjusted life years (DALYs) in China, imposing a heavy burden on society and families.
- Trial name
- AURORA (NCT06009315)
- Where
- China
- Volunteers
- 949 people
- Sponsor
- Beijing Tiantan Hospital
Stroke, Acute, Stroke, Ischemic
Carotid Artery Stenting During Endovascular Treatment of Acute Stroke
Rationale: Approximately 20% of the patients with acute ischemic stroke due to an intracranial large vessel occlusion (LVO) has a high-grade stenosis in the ipsilateral cervical carotid artery.
- Conditions
- Stroke, Acute, Stroke, Ischemic, Carotid Stenosis, Carotid Atherosclerosis
- Trial name
- CASES (NCT06511089)
- Testing
- carotid artery stenting during EVT, no carotid artery stenting during EVT
- Where
- Netherlands
- Volunteers
- 600 people
- Sponsor
- University Medical Center Groningen
Ischemic Stroke, Acute, TIA
Tirofiban for Patients With intraCranial Artery Stenosis and High-risk Acute Non-disabling Cerebrovascular Events(CHANCE-4）
This is a multicenter, double-blind, double-dummy, randomized clinical trial comparing the efficacy and safety of tirofiban versus placebo in preventing recurrence of stroke for patients with intracranial artery stenosis and…
- Conditions
- Ischemic Stroke, Acute, TIA, Symptomatic Intracranial Artery Stenosis
- Trial name
- NCT06319846
- Testing
- Tirofiban
- Where
- 5 sites in China
- Volunteers
- 4,674 people
- Sponsor
- Beijing Tiantan Hospital
Acute Stroke, Functional Recovery
Prognostic Recovery Observations and Guidance for Evaluating Stroke Survivors
This research delves into the acute prognostic factors influencing functional recovery in individuals who have experienced a stroke.
- Conditions
- Acute Stroke, Functional Recovery, Prognostic Factors
- Trial name
- PROGRESS (NCT06465758)
- Where
- Italy
- Volunteers
- 360 people
- Sponsor
- IRCCS San Raffaele
Quality of Life, Stroke, Acute
Cerebrovascular Disease: Quality of Life (CODE: QoL)
The goal of this observational study is to learn about quality of life, stress and caregiver burden in patients with stroke and their caregivers.
- Conditions
- Quality of Life, Stroke, Acute, Sexual Behavior, Stress
- Trial name
- CODE:QoL (NCT06443268)
- Testing
- questionnaire, hair samples, blood samples, clinical exam
- Where
- Switzerland
- Volunteers
- 680 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Acute Ischemic Stroke
Registry of Acute Ischemic Stroke With Large- or Medium-vessel Occlusion
This study is designed to observe the treatment options in real-world clinical practice as well as the safety and efficacy of different treatment strategies.
- Trial name
- LOMEVO (NCT05779215)
- Testing
- Visit at D90
- Where
- China
- Volunteers
- 50,000 people
- Sponsor
- Xuanwu Hospital, Beijing
Acute Ischemic Stroke
Mechanical Thrombectomy of Acute Ischemic Stroke Anterior Circulation Distal Vessel Occlusion
Ischemic stroke continues to be of the leading causes of disability and death. Distal vessel occlusion one of most presenting and disabling varieties of ischemic stroke.
- Trial name
- NCT06427187
- Testing
- an array of devices are used in thrombectomy. These include guide catheters, stent-retrievers, microcatheters, aspiration catheters, and aspiration pump systems
- Volunteers
- 30 people
- Sponsor
- Assiut University
Stroke, Acute Ischemic
Tirofiban for Successful Endovascular Stroke Thrombectomy
Up to 50% of acute ischemic stroke patients with large vessel occlusion failed to achieve functional independence even after successful reperfusion therapy, a phenomenon that is referred to as "futile recanalization".
- Trial name
- ADJUVANT-2 (NCT06373042)
- Testing
- Intraarterial and intravenous tirofiban
- Volunteers
- 712 people
- Sponsor
- Zhongming Qiu
Stroke, Acute, Pre-hospital Triage
Stroke Triage Optimization by Ambulance Paramedics in the Pre-hospital Setting
There are everal scales designed to help ambulance paramedics to identify a patient with a stroke and activate a stroke code. These scales were never tested in the field in a large unselected patient sample.
- Conditions
- Stroke, Acute, Pre-hospital Triage, Stroke Treatment, Stroke Code
- Trial name
- STROKE-APP (NCT06332989)
- Testing
- stroke-APP
- Where
- Netherlands
- Volunteers
- 3,000 people
- Sponsor
- Leiden University Medical Center
Acute Ischemic Stroke
Safety and Efficacy of Urinary Kallidinogenase for Large Artery Atherosclerosis Acute Ischemic Stroke
The purpose of this study is to evaluate the safety and efficacy of urinary kallidinogenase treatment in patients with large artery atherosclerotic acute ischemic stroke.
- Trial name
- NCT06137300
- Testing
- Urinary kallidinogenase for injection, Guideline-prescribed medical therapy
- Where
- China
- Volunteers
- 986 people
- Sponsor
- Yi Yang
Acute Ischemic Stroke
Effect of Ginkgo Biloba Extract on Cognitive Function in Acute Ischemic Stroke
The purpose of this study is to determine the effect of ginkgo biloba extract on cognitive function in acute ischemic stroke.
- Trial name
- NCT06140888
- Testing
- Ginkgo Biloba Extract
- Volunteers
- 356 people
- Sponsor
- Yi Yang
Stroke, Acute
Acute Stroke: Prehospital Versus In-HospitAL Initiation of Recanalization Therapy- ASPHALT
ASPHALT is an academic-driven open-label randomized controlled trial of Mobile Stroke Unit (MSU) deployment versus standard care in France, with blinded assessment of efficacy endpoints.
- Trial name
- ASPHALT (NCT05649670)
- Testing
- Mobile Stroke Unit deployment
- Where
- 11 sites in France
- Volunteers
- 450 people
- Sponsor
- Centre Hospitalier St Anne
Acute Ischemic Stroke, Thrombolysis
Application of Standardized Green Channel Treatment System for Ischemic Stroke in Xi 'an
Objective: To observe the practical application of the standardized green channel treatment system for stroke in Xi 'an in the real world.
- Conditions
- Acute Ischemic Stroke, Thrombolysis, Endovascular Treatment
- Trial name
- Asgctsis (NCT05424978)
- Testing
- Standardized green channel treatment methods for stroke
- Where
- China
- Volunteers
- 3,600 people
- Sponsor
- Xi'an No.3 Hospital