Clinical trials: Acute Stroke Intervention
Stroke
Direct Transfer to an Endovascular Center Compared to Transfer to the Closest Stroke Center in Acute Stroke Patients With Suspected Large Vessel Occlusion
To evaluate the hypothesis that direct transfer to an Endovascular Stroke Center, compared to transfer to the closest Local Stroke Center, offers a better outcome in the distribution of the modified Rankin Scale scores at 90 days…
- Trial name
- RACECAT (NCT02795962)
- Testing
- Direct transfer to an Endovascular Center
- Where
- 12 sites in Spain
- Volunteers
- 1,401 people
- Sponsor
- Fundacio Ictus Malaltia Vascular
Acute Stroke
International Multicenter Registry for Mechanical Recanalization Procedures in Acute Stroke
The purpose of the Endostroke Registry is to gather information on predictors of good or poor clinical outcome following mechanical recanalization therapies for acute ischemic stroke.
- Trial name
- ENDOSTROKE (NCT01399762)
- Testing
- mechanical recanalization
- Where
- 13 sites in Austria, Germany
- Volunteers
- 500 people
- Sponsor
- Goethe University
Acute Ichemic Stroke, Brain Ischemia
Multimodal Investigation of Intracranial Clot Environment
Analysis of peri clot blood collected at the acute phase of stroke in order to understand physiopathological mechanisms involved in the cerebrovascular damage
- Trial name
- MISO (NCT04421326)
- Testing
- Analysis of the clot
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Montpellier
Ischemic Stroke, Acute Stroke
Aerobic Exercise Training in Acute Ischaemic Stroke
Stroke is a leading cause of adult disability in the UK. There are few treatment options that improve long-term disability outcomes after stroke.
- Conditions
- Ischemic Stroke, Acute Stroke, Cerebrovascular Accident
- Trial name
- ATAS (NCT04742686)
- Testing
- Aerobic exercise training
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Sheffield Hallam University
Ischemic Stroke, Acute Ischemic Stroke
Virtual Intervention Stroke Initiative
The goal of this clinical trial is to determine if patients admitted to a primary stroke centre, such as the general internal medicine service of the Ottawa Hospitals General Campus, for acute ischemic stroke would benefit from a…
- Trial name
- VISION (NCT05875389)
- Testing
- Virtual assessment
- Volunteers
- 80 people
- Sponsor
- Ottawa Hospital Research Institute
Acute Stroke
Cerebral Blood Flow-guided Early Rehabilitation Intervention After Stroke: a Pilot Randomized Trial (STAND-OP)
The primary goal of most acute stroke interventions is to restore cerebral blood flow (CBF) in the affected region and prevent hypoperfusion during early clinical course.
- Trial name
- STAND-OP (NCT04848285)
- Testing
- Early Mobilization, Standard care
- Where
- Spain
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Acute Cerebrovascular Accident, Endovascular Procedures
PROMISE (Somatosensory Evoked POtEntials MonItoring During Acute Ischemic StrokE) Study
Endovascular treatment in patients with acute ischemic stroke due to large vessel occlusion does not always lead to good clinical and functional outcome, despite achieving complete arterial recanalization.
- Trial name
- PROMISE (NCT04099615)
- Testing
- Somatosensory Evoked Potentials
- Where
- Spain
- Volunteers
- 228 people
- Sponsor
- Fundació Institut Germans Trias i Pujol
Stroke
Wake up Symptomatic Stroke - Benefit of Intravenous Clot Busters or Endovascular Intervention
The purpose of the trial is to study the safety and the effectiveness of using CT Perfusion studies as an indicator to treat stroke patients with unknown time of onset.
- Trial name
- WASSABI (NCT01455935)
- Testing
- Anti-platelets and statin, alteplase, intra arterial intervention
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Jacobs Neurological Institute
Stroke, Ischemic
A Study of the Use of the Q Aspiration Catheter to Remove Clot in Stroke Patients
The purpose of this study is to collect real-world safety and performance data on the MIVI Neuroscience, Inc. Q Aspiration Catheter for use in the removal of fresh, soft emboli and thrombi in the neurovascular system during acute…
- Trial name
- TAPAS (NCT04089917)
- Testing
- Q Aspiration Catheter
- Where
- 4 sites in Spain
- Volunteers
- 45 people
- Sponsor
- MIVI Neuroscience, Inc.
Ischemic Stroke, Hypertension
Optimization of Blood Pressure Management After Acute Ischemic Stroke and Its Prognostic Significance
BOSS-Trial I is a phase 2 clinical trial with the following objectives; 1. to prove the feasibility of a Bluetooth-equipped sphygmomanometer system in real-world clinical practice and wireless connection to the main server; 2.
- Trial name
- NCT03024476
- Testing
- Behavioral intensification, Pharmacological intensification based on olmesartan, Bluetooth-equipped sphygmomanometer
- Where
- 3 sites in South Korea
- Volunteers
- 67 people
- Sponsor
- Seoul National University Bundang Hospital
Stroke, Apoplexy
Healthy Lifestyles After Stroke - Stroke Coach
The purpose of this study is to examine the efficacy of a lifestyle modification telehealth program on health-related behaviours in community-dwelling individuals living with stroke.
- Conditions
- Stroke, Apoplexy, Cerebral Stroke, Cerebrovascular Accident
- Trial name
- StrokeCoach (NCT02207023)
- Testing
- Healthy Lifestyle Training Program
- Where
- 7 sites in Canada
- Volunteers
- 126 people
- Sponsor
- University of British Columbia
Stroke, Brain Ischemia
Use of Dexmedetomidine in Acute Stroke and Cerebral Vasospasm Interventions
Dexmedetomidine is a unique sedative medication able to provide sedation without causing respiratory depression and maintaining neurological functions.
- Conditions
- Stroke, Brain Ischemia, Vasospasm, Intracranial, Hemorrhage, Intracranial
- Trial name
- NCT01845441
- Testing
- Dexmedetomidine, Fentanyl, Midazolam
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University Hospitals Cleveland Medical Center
Acute Ischemic Stroke
An Application That Can Provide Early Warning of Temperature Health Risks and Give Protective Suggestions or Personalized Suggestions Based on Patients' Own Secondary Prevention Risk Factors Was Applied to Intervene, and the Intervention Effect of APP on Stroke Recurrence Risk Was Analyzed
This study employs individualized temperature health risk early warning and risk factor management interventions for stroke, and explores their actual intervention effects.
- Trial name
- NCT06904664
- Testing
- Individualized temperature health risk early warning and risk factor management, Temperature health risk early warning, Risk factor management
- Volunteers
- 10,184 people
- Sponsor
- Xuanwu Hospital, Beijing
Acute Ischemic Stroke
C-arm Cone Beam CTP Guided Cerebrovascular Interventions
The study objective for the Phase 2 of this research is to demonstrate and confirm the substantial time savings that can be obtained using cone beam computed tomography (CB-CT) for both complete image acquisition and rapid image…
- Trial name
- NCT05536895
- Testing
- C-Arm Cone Beam Computed Tomography, Multi-detector Computed Tomography
- Where
- United States
- Sponsor
- University of Wisconsin, Madison
Stroke
The ARCAS Study: Auditory Rhythmical Cueing for Gait in Acute Stroke
Difficulties with walking is a common and distressing problem following stroke and can lead to reduced independence. Research suggests that using an auditory cue, such as a regular beat or pulse, as part of rehabilitation can…
- Trial name
- ARCAS (NCT04795115)
- Testing
- Auditory rhythmical cueing
- Where
- United Kingdom
- Volunteers
- 12 people
- Sponsor
- Northumbria Healthcare NHS Foundation Trust
Stroke, Acute
FRALYSE Trial: Comparison of the Classical Rt-PA Procedure With a Longer Procedure in Acute Ischemic Stroke
Data from the literature have suggested that a longer time of thrombolysis might be more effective in ischemic stroke. We, the investigators at Hospices Civils de Lyon, have designed a randomized protocol to test this hypothesis.
- Trial name
- NCT00132509
- Testing
- DFIL, NINDS
- Where
- France
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Acute Ischemic Stroke
Effectiveness of Early Intervention With Virtual Reality-Based Interactive Rehabilitation on Upper Extremity Muscle Strength, Cognitive Status, Hospital Anxiety, and Exercise Self-Efficacy in Patients With Acute Ischemic Stroke
This interventional study evaluates the impact of early virtual rehabilitation, starting 24 hours post-diagnosis of acute ischemic stroke, on upper limb strength, cognitive status, and self-efficacy.
- Trial name
- NCT07674329
- Testing
- Virtual reality-based interactive rehabilitation, bedside rehabilitation
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- Tri-Service General Hospital (TSGH)
Stroke, Acute, Stroke
Efficacy of a Telehealth Delivered Group Lifestyle Balance for People Post Stroke (tGLB-CVA)
Investigators will conduct a randomized controlled trial (RCT) to assess intervention efficacy of telehealth delivery of the GLB-CVA (tGLB-CVA) compared to a 6-month wait-list control (WLC) in partnership with a diverse group of…
- Conditions
- Stroke, Acute, Stroke, Stroke, Cardiovascular, Stroke (CVA) or TIA
- Trial name
- tGLB-CVA (NCT06569121)
- Testing
- Group Lifestyle Balance for People Post Stroke (GLB-CVA)
- Where
- United States
- Volunteers
- 94 people
- Sponsor
- Baylor Research Institute
Acute Ischemic Stroke, Large Vessel Occlusion
Direct Angio Suite Acute Stroke Intervention With CT/DSA Hybrid Emergency Stroke Unit
This study investigates whether direct transfer to an emergency stroke unit equipped with NeuAngio-CT reduces time to endovascular reperfusion in patients with acute ischemic stroke and suspected intracranial large-vessel…
- Trial name
- NCT07670065
- Testing
- Direct Angio Suite Acute Stroke Intervention With CT/DSA Hybrid Emergency Stroke Unit, Conventional Thrombectomy
- Where
- China
- Volunteers
- 232 people
- Sponsor
- Beijing Tiantan Hospital
Intracranial Aneurysm, Cerebral Aneurysm
Safety and Clinical Effectiveness of Pipeline™ Shield Devices for Intracranial Aneurysms
This observational, retrospective, single-arm, multi-centre cohort study will use real-world data (RWD) to develop real-world evidence (RWE) of the safety and clinical effectiveness of the Pipeline™ Flex Embolization Device with…
- Conditions
- Intracranial Aneurysm, Cerebral Aneurysm, Subarachnoid Hemorrhage, Stroke, Acute
- Trial name
- SCOPE-AUS (NCT03815149)
- Testing
- Pipeline™ Flex Embolization Device with Shield Technology™
- Where
- 4 sites in Australia
- Volunteers
- 500 people
- Sponsor
- Gold Coast Hospital and Health Service