Clinical trials: Acute Viral Bronchiolitis.
Acute Bronchiolitis, Viral Bronchiolitis
Internal Jugular Vein Respiratory Variability as a Marker of Disease Severity in Infant Bronchiolitis
This prospective observational cohort study evaluates whether respiratory-cycle variation in internal jugular vein (IJV) diameter, measured by point-of-care ultrasound, correlates with clinical disease severity in infants 1-23…
- Conditions
- Acute Bronchiolitis, Viral Bronchiolitis, Respiratory Syncytial Virus Infections
- Trial name
- IJV-BRONCH (NCT07778225)
- Testing
- Point-of-Care Ultrasonography
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Eskisehir Osmangazi University
Bronchiolitis
Inhaled Hypertonic Saline Use in the Emergency Department to Treat Acute Viral Bronchiolitis
Acute viral bronchiolitis is an extremely common childhood disease, responsible for approximately 17% of childhood admissions to hospital per year, with an annually cost that reaches U$ 500 million.
- Trial name
- NCT02045238
- Testing
- Hypertonic Saline, Chest X-Ray, Respiratory virus screening test
- Where
- Brazil
- Volunteers
- 32 people
- Sponsor
- University of Sao Paulo
Bronchiolitis, Respiratory Disease
Isotonic Saline for Children With Bronchiolitis
The goal of this randomized clinical trial is to investigate the optimal supportive treatment of bronchiolitis in infants from 0-12 months of age.
- Conditions
- Bronchiolitis, Respiratory Disease, Asthma in Children, Viral Infection
- Trial name
- NCT05902702
- Testing
- Nebulized isotonic saline, Nasal irrigation with isotonic saline
- Volunteers
- 300 people
- Sponsor
- Slagelse Hospital
Bronchiolitis, Viral
Efficacy and Safety of Curosurf® in Patients Invasively Ventilated for Severe Bronchiolitis Under 12 Months of Age
Background. Viral bronchiolitis is a common cause of hospitalization for acute respiratory insufficiency in young infants. Despite several RCT have tested the effectiveness of various agents, currently there is no proven specific…
- Trial name
- NCT03959384
- Testing
- Curosurf 80Mg/Ml Intratracheal Suspension, Ambient Air
- Where
- Italy
- Volunteers
- 9 people
- Sponsor
- Azienda Ospedaliera Universitaria Integrata Verona
Acute Viral Bronchiolitis
Respiratory Physiotherapy and Hospitalization in Infants With Bronchiolitis
Acute Viral Bronchiolitis (AVB) is one of the leading causes of respiratory illness and hospitalization among infants during the first year of life, generating a substantial burden on healthcare services and public health…
- Trial name
- BVA-RESP (NCT07682844)
- Testing
- Outpatient Respiratory Physiotherapy
- Where
- Brazil
- Volunteers
- 1,000 people
- Sponsor
- University of Sao Paulo
Bronchiolitis
Nebulized 5% Hypertonic Saline for the Treatment of Bronchiolitis
The investigators reasoned that a hypertonic saline concentration higher than 3% could be safe and more efficacious in the treatment of bronchiolitis, alleviating severe symptoms and preventing the need for hospitalization in…
- Trial name
- NCT01016249
- Testing
- Treatment 1. (5% Hypertonic saline + Epinephrine), Treatment 3. (3% Hypertonic saline + Epinephrine), Treatment 2. (Normal saline + Epinephrine)
- Where
- Qatar
- Volunteers
- 187 people
- Sponsor
- Hamad Medical Corporation
Bronchiolitis, Viral
Single Injection of Dexamethasone for Acute Bronchiolitis in Young Children
The purpose of this study was to determine whether a single intramuscular injection of dexamethasone decreased the duration of symptoms of acute bronchiolitis in young children.
- Trial name
- NCT00122785
- Testing
- dexamethasone
- Where
- Thailand
- Volunteers
- 170 people
- Sponsor
- Khon Kaen University
Bronchiolitis, Viral, Pneumonia, Viral
Pediatric Helmet CPAP Pilot Study
This a research study to find out whether giving Continuous Positive Airway Pressure (CPAP) through a Helmet is the same or better than giving CPAP through a Facemask, Nasal Mask, or Nasal Prongs.
- Conditions
- Bronchiolitis, Viral, Pneumonia, Viral, Pneumonia, Bacterial
- Trial name
- NCT04764929
- Testing
- Helmet CPAP
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Columbia University
Acute Bronchiolitis Due to Respiratory Syncytial Virus, Bronchiolitis Acute
Mucociliary Clearance Techniques for Acute Bronchiolitis
To assess the efficacy of mucociliary clearance techniques in non-hospitalised infants with a first episode of mild to moderate acute bronchiolitis.
- Conditions
- Acute Bronchiolitis Due to Respiratory Syncytial Virus, Bronchiolitis Acute, Bronchiolitis Acute Viral
- Trial name
- CLEARBRONCH (NCT06689631)
- Testing
- Respiratory Physiotherapy
- Volunteers
- 70 people
- Sponsor
- Universidad de León
Bronchiolitis Acute Viral
Oral Prednisolone for Acute Rhinovirus Induced Wheezing in Children Less Than 2 Years of Age
The aim of the trial is to evaluate whether the use of oral prednisolone directed by point-of-care testing is useful in acute wheezing caused by rhinovirus in children aged 6-24 months.
- Trial name
- RhinoPOCRCT (NCT05444699)
- Testing
- Prednisolone Sodium Phosphate, Sugar syrup
- Where
- 2 sites in Finland
- Volunteers
- 210 people
- Sponsor
- University of Oulu
Acute Viral Bronchiolitis.
HYPERTONIC SALINE IN ACUTE VIRAL BRONCHIOLITIS: A RANDOMIZED CLINICAL TRIAL
The purpose of this study is to determine whether nebulized hypertonic saline solution reduces the admission rate 48 hours after initial treatment in the emergency department, when compared to normal saline solution (placebo).
- Trial name
- NCT00729274
- Testing
- normal saline solution
- Where
- Canada
- Sponsor
- Laval University
Bronchiolitis, Wheezing
Montelukast for Acute Bronchiolitis and Postbronchiolitis Viral Induced Wheezing
The aim of the current study is to evaluate the effect of Montelukast in treatment of acute bronchiolitis and postbronchiolitis viral induced wheezing of infants 3 to 12 months of age in Bandar Abbas Children' hospital.
- Conditions
- Bronchiolitis, Wheezing, Cough
- Trial name
- NCT01370187
- Testing
- Montelukast
- Where
- Iran
- Volunteers
- 146 people
- Sponsor
- Hormozgan University of Medical Sciences
Immune and Microbial Reconstitution, Systemic Viral Infection
Monitoring of Immune and Microbial Reconstitution in (HCT) and Novel Immunotherapies
This protocol serves as a mechanism to collect, store, and distribute bodily fluid and tissue samples obtained from Hematopoietic Cell Transplant (HCT) or novel immunotherapy patients and their donors at the Masonic Cancer Center…
- Conditions
- Immune and Microbial Reconstitution, Systemic Viral Infection, Acute-graft-versus-host Disease, Chronic Graft-versus-host-disease
- Trial name
- NCT03557749
- Testing
- Blood Sample, Stool Sample, Urine Sample
- Where
- United States
- Volunteers
- 210 people
- Sponsor
- Masonic Cancer Center, University of Minnesota
Acute Viral Bronchiolitis
KL-6 Protein as a Biomarker of Lung Injury in Viral Bronchiolitis
Serum KL-6 protein has been described as a biomarker of epithelial lung injury in Respiratory Syncytial Virus bronchiolitis. The investigators can imagine that epithelial injury intensity has consequences on immediate and later…
- Trial name
- NCT01437956
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Bronchiolitis, Viral
Etude PROTECT : Prognostic Role of Tapse Evaluation in Children's bronchioliTis
In this prospective study, we aim to evaluate the association between an echocardiographic marker of right ventricular systolic function, the TAPSE (Tricuspid Annular Plane Systolic Excursion), and poor outcome in patients…
- Trial name
- PROTECT (NCT07209956)
- Testing
- Echocardiographic assessment of TAPSE
- Where
- France
- Volunteers
- 46 people
- Sponsor
- University Hospital, Bordeaux
Bronchiolitis
Trial of Montelukast for Treatment of Acute Bronchiolitis
The primary rationale for this study is to evaluate the effect of once daily montelukast on duration of acute illness in infants with first-time bronchiolitis.
- Trial name
- NCT00863317
- Testing
- montelukast sodium, sucrose
- Where
- United States
- Volunteers
- 141 people
- Sponsor
- Medical College of Wisconsin
Bronchiolitis, Bronchiolitis Acute Viral
Analysis of Variability in the Management of Respiratory Infections in Hospitalized Patients Under 2 Years of Age
Medical practice variability refers to differences in treatment and clinical outcomes that cannot be solely explained by patient characteristics or medical conditions.
- Trial name
- NCT07202585
- Where
- Argentina
- Volunteers
- 127 people
- Sponsor
- Hospital General de Niños Pedro de Elizalde
Hepatitis C
DAA-based Therapy for Recently Acquired Hepatitis C II (DAA = Directly Acting Antiviral)
The purpose of the study is to examine whether patients who have acute or early chronic hepatitis C virus (HCV) infection can be treated effectively and safely with an interferon-sparing regimen that combines a new direct acting…
- Trial name
- DARE-C II (NCT02156570)
- Testing
- Sofosbuvir and ribavirin
- Where
- 5 sites in Australia, New Zealand
- Volunteers
- 20 people
- Sponsor
- Kirby Institute
Viral Bronchiolitis
Evaluation of Chest Physiotherapy for Acute Bronchiolitis in Toddlers (BRONKINOU)
The purpose of this study is to determine whether chest physiotherapy with forced expiratory technique reduces delay of healing in acute bronchiolitis of children between 15 days and 24 months of age.
- Trial name
- BRONKINOU (NCT00125450)
- Testing
- Chest Physiotherapy with Forced Expiratory Technique, Nasopharyngeal Aspiration
- Where
- 7 sites in France
- Volunteers
- 500 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Acute Bronchiolitis
Efficacy Of Combined Nebulized Hypertonic Saline and Chest Percussion Therapy in Acute Viral Bronchiolitis
This study will examine the efficacy of combined nebulized hypertonic saline with chest percussion therapy in patients age 0 to 24 months admitted to the general inpatient pediatrics unit with acute bronchiolitis.
- Trial name
- NCT06441162
- Testing
- Nebulized 3% sodium chloride solution, Chest percussion cups
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- NYU Langone Health